49 research outputs found

    Letter to President H.A. Morgan from John R. Weathers with News Article Enclosed

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    How Postsecondary Education Improves Adult Outcomes for Supplemental Security Income Children with Severe Hearing Impairments

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    This is a case study of SSI children who apply for postsecondary education at the National Technical Institute of the Deaf (NTID) within the Rochester Institute of Technology. We estimate the likelihood that an SSI child will graduate from NTID relative to other hearing impaired NTID applicants and estimate the influence of graduation from NTID on participation in the SSI adult program and later success in the labor market. To do so we create a unique longitudinal administrative records data set (n=5,638) based on administrative records from NTID linked to Social Security Administration (SSA) microdata. We find that SSI children who graduate from NTID spend less time on the SSI adult program and have higher earnings than those who do not graduate. However, we also find that SSI children who apply to NTID have a greater risk of not graduating than their fellow deaf students who did not participate in the SSI program as children. Our findings suggest that greater effort may be necessary to prepare SSI children for postsecondary education and that the currently SSA-funded youth transition demonstration projects are necessary to explore how such efforts can improve adult outcomes for SSI children with disabilities

    Macrosystems ecology: Understanding ecological patterns and processes at continental scales

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    Macrosystems ecology is the study of diverse ecological phenomena at the scale of regions to continents and their interactions with phenomena at other scales. This emerging subdiscipline addresses ecological questions and environmental problems at these broad scales. Here, we describe this new field, show how it relates to modern ecological study, and highlight opportunities that stem from taking a macrosystems perspective. We present a hierarchical framework for investigating macrosystems at any level of ecological organization and in relation to broader and finer scales. Building on well-established theory and concepts from other subdisciplines of ecology, we identify feedbacks, linkages among distant regions, and interactions that cross scales of space and time as the most likely sources of unexpected and novel behaviors in macrosystems. We present three examples that highlight the importance of this multiscaled systems perspective for understanding the ecology of regions to continents

    Training macrosystems scientists requires both interpersonal and technical skills

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    Macrosystems science strives to integrate patterns and processes that span regional to continental scales. The scope of such research often necessitates the involvement of large interdisciplinary and/or multi-institutional teams composed of scientists across a range of career stages, a diversity that requires researchers to hone both technical and interpersonal skills. We surveyed participants in macrosystems projects funded by the US National Science Foundation to assess the perceived importance of different skills needed in their research, as well as the types of training they received. Survey results revealed a mismatch between the skills participants perceive as important and the training they received, particularly for interpersonal and management skills. We highlight lessons learned from macrosystems training case studies, explore avenues for further improvement of undergraduate and graduate education, and discuss other training opportunities for macrosystems scientists. Given the trend toward interdisciplinary research beyond the macrosystems community, these insights are broadly applicable for scientists involved in diverse, collaborative projects.https://esajournals.onlinelibrary.wiley.com/doi/full/10.1002/fee.228

    Anti-plasmodial polyvalent interactions in Artemisia annua L. aqueous extract – possible synergistic and resistance mechanisms

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    Artemisia annua hot water infusion (tea) has been used in in vitro experiments against P. falciparum malaria parasites to test potency relative to equivalent pure artemisinin. High performance liquid chromatography (HPLC) and mass spectrometric analyses were employed to determine the metabolite profile of tea including the concentrations of artemisinin (47.5±0.8 mg L-1), dihydroartemisinic acid (70.0±0.3 mg L-1), arteannuin B (1.3±0.0 mg L-1), isovitexin (105.0±7.2 mg L-1) and a range of polyphenolic acids. The tea extract, purified compounds from the extract, and the combination of artemisinin with the purified compounds were tested against chloroquine sensitive and chloroquine resistant strains of P. falciparum using the DNA-intercalative SYBR Green I assay. The results of these in vitro tests and of isobologram analyses of combination effects showed mild to strong antagonistic interactions between artemisinin and the compounds (9-epi-artemisinin and artemisitene) extracted from A. annua with significant (IC50 <1 μM) anti-plasmodial activities for the combination range evaluated. Mono-caffeoylquinic acids, tri-caffeoylquinic acid, artemisinic acid and arteannuin B showed additive interaction while rosmarinic acid showed synergistic interaction with artemisinin in the chloroquine sensitive strain at a combination ratio of 1:3 (artemisinin to purified compound). In the chloroquine resistant parasite, using the same ratio, these compounds strongly antagonised artemisinin anti-plasmodial activity with the exception of arteannuin B, which was synergistic. This result would suggest a mechanism targeting parasite resistance defenses for arteannuin B’s potentiation of artemisinin

    Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study

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    <p>Abstract</p> <p>Background</p> <p>The long term adverse effects of Severe Acute Respiratory Syndrome (SARS), a viral disease, are poorly understood.</p> <p>Methods</p> <p>Sleep physiology, somatic and mood symptoms of 22 Toronto subjects, 21 of whom were healthcare workers, (19 females, 3 males, mean age 46.29 yrs.+/- 11.02) who remained unable to return to their former occupation (mean 19.8 months, range: 13 to 36 months following SARS) were compared to 7 healthy female subjects. Because of their clinical similarities to patients with fibromyalgia syndrome (FMS) these post-SARS subjects were similarly compared to 21 drug free female patients, (mean age 42.4 +/- 11.8 yrs.) who fulfilled criteria for fibromyalgia.</p> <p>Results</p> <p>Chronic post-SARS is characterized by persistent fatigue, diffuse myalgia, weakness, depression, and nonrestorative sleep with associated REM-related apneas/hypopneas, an elevated sleep EEG cyclical alternating pattern, and alpha EEG sleep anomaly. Post- SARS patients had symptoms of pre and post-sleep fatigue and post sleep sleepiness that were similar to the symptoms of patients with FMS, and similar to symptoms of patients with chronic fatigue syndrome. Both post-SARS and FMS groups had sleep instability as indicated by the high sleep EEG cyclical alternating pattern rate. The post-SARS group had a lower rating of the alpha EEG sleep anomaly as compared to the FMS patients. The post-SARS group also reported less pre-sleep and post-sleep musculoskeletal pain symptoms.</p> <p>Conclusions</p> <p>The clinical and sleep features of chronic post-SARS form a syndrome of chronic fatigue, pain, weakness, depression and sleep disturbance, which overlaps with the clinical and sleep features of FMS and chronic fatigue syndrome.</p

    How Postsecondary Education Improves Adult Outcomes for Supplemental Security Income Children with Severe Hearing Impairments

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    For more information on this paper, contact Robert Weathers: [email protected] is a case study of SSI children who apply for postsecondary education at the National Technical Institute of the Deaf (NTID) within the Rochester Institute of Technology. We estimate the likelihood that an SSI child will graduate from NTID relative to other hearing impaired NTID applicants and estimate the influence of graduation from NTID on participation in the SSI adult program and later success in the labor market. To do so we create a unique longitudinal administrative records data set (n=5,638) based on administrative records from NTID linked to Social Security Administration (SSA) microdata. We find that SSI children who graduate from NTID spend less time on the SSI adult program and have higher earnings than those who do not graduate. However, we also find that SSI children who apply to NTID have a greater risk of not graduating than their fellow deaf students who did not participate in the SSI program as children. Our findings suggest that greater effort may be necessary to prepare SSI children for postsecondary education and that the currently SSA-funded youth transition demonstration projects are necessary to explore how such efforts can improve adult outcomes for SSI children with disabilities.DE95A_PDF1.pdf: 143 downloads, before Oct. 1, 2020
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