Can the memsahib speak? A re-examination of the tropes and stereotypes surrounding the Anglo-Indian female during the Indian Rebellion of 1857

This essay offers an exploration of the tropes and stereotypes that came to define the Anglo-Indian female during the Indian Rebellion of 1857. Powerful at the time, these notions of imperial femininity survived within subsequent androcentric historical discourse. Through an in depth analysis of female accounts of the Rebellion, evidence can be uncovered that gainsays these accepted 'truths,' particularly the mutual exclusivity of male and female realms. This essay documents how the dominant stereotypes of women as 'helpless,' 'domestic' and 'passive' were founded in male narratives of 1857, but also subverted in those of female authorship. The most potent and lasting trope of femininity surrounding the Rebellion, the 'fallen woman,' is also shown to be a product of a heavily gendered discourse in which women were conspicuously silenced

Investigating Moral Underpinnings Of Attitudes About Abortion

The present study examines the ways in which moral values, specifically purity and fairness, may influence individual attitudes about abortion. Participants were asked to complete the Moral Foundations Questionnaire (MFQ) and read a scenario created for the purposes of this study about a hypothetical woman who decides to have an abortion. After reading this, participants rated how warmly they felt towards this woman, how they perceived her moral character, to what extent they believed she deserved blame, and lastly, whether they believed abortion access today should remain the same or to what extent they felt it should be increased or decreased. We hypothesized that those who endorsed purity values would be more likely to feel less warmly toward the woman in the story, rate her moral character negatively, think she deserved more blame, and support a decrease in abortion access. Conversely, we expected those who endorsed fairness would feel more warmth, report higher rankings of moral character, attribute less blame, and support an increase in abortion access. The results supported these predictions and interestingly, the moral values of purity and fairness remain the main predictor of one’s attitudes on abortion, even when controlling for political ideology. This study could have implications for weakening the partisan divide regarding abortion debates and suggestions for future studies on this topic

Food safety investments in East Africa

Foodborne diseases are a threat to public health. They also impose an enormous economic burden, affect food and nutrition security, and can hinder market access and disrupt livelihoods. In 2017–2018, the Global Food Safety Partnership (GFSP), a public-private initiative hosted by the World Bank, undertook an intensive analysis of recent food safety investments in sub-Saharan Africa. GFSP built a database of projects and interviewed key informants. We reviewed the food safety investment database, and data related to countries in East Africa was extracted

Resolving the unresolved: online microdialysis coupled to ICPQQQ for the simultaneous sampling and analysis of dissolved elements in soil solution

Assessing rapid chemical-elemental reactions in soils is significantly inhibited by the spatial and temporal resolution of current sampling techniques [RhizonTM samplers, diffusive gradients in thin films (DGTs)]1 . Soil chemistry is typically investigated over hours-days-weeks and with poor sampling density; the vast majority of reactions occur within seconds-minutes. Microdialysis (MD) is a new technique in the field of soil science that uses small probes to sample compounds dissolved in soil solution, with minimal disturbance to the external environment2 . Initially developed for use in neuroscience, MD has the potential for translation to environmental geochemistry to define soil chemical/physical parameters, and better inform predictive models for soil-to-plant transfer of potentially harmful elements (PHEs) or essential nutrients. One considerable experimental challenge for MD is balancing the target analyte recovery efficiency with the sample volume required for the analytical chemistry technique, which can significantly affect how often elemental speciation changes and soil fixation events can be measured3 . To overcome this challenge, we have begun development of a novel integrated online MD sampling and analysis technique, through direct coupling of MD probes with triple quadrupole inductively coupled plasma mass spectrometry (ICP-QQQ) using a microflow total consumption nebulizer with no additional modifications. This poster will present the initial setup, optimisation and application of the technique to the sampling and analysis of multiple elements in soil solution, alongside future perspectives on how information gained from this promising technique can contribute to the management of global societal and agricultural issues (e.g. nutrient supply to staple crops, contaminated land remediation)

Detection and management of familial hypercholesterolaemia in primary care in Australia: protocol for a pragmatic cluster intervention study with pre-post intervention comparisons

Introduction: Familial hypercholesterolaemia (FH), an autosomal dominant disorder of lipid metabolism, results in accelerated onset of atherosclerosis if left untreated. Lifelong treatment with diet, lifestyle modifications and statins enable a normal lifespan for most patients. Early diagnosis is critical. This protocol trials a primary care-based model of care (MoC) to improve detection and management of FH. Methods and analysis: Pragmatic cluster intervention study with pre-post intervention comparisons in Australian general practices. At study baseline, current FH detection practice is assessed. Medical records over 2 years are electronically scanned using a data extraction tool (TARB-Ex) to identify patients at increased risk. High-risk patients are clinically reviewed to provide definitive, phenotypic diagnosis using Dutch Lipid Clinic Network Criteria. Once an index family member with FH is identified, the primary care team undertake cascade testing of first-degree relatives to identify other patients with FH. Management guidance based on disease complexity is provided to the primary care team. Study follow-up to 12 months with TARB-Ex rerun to identify total number of new FH cases diagnosed over study period (via TARB-Ex, cascade testing and new cases presenting). At study conclusion, patient and clinical staff perceptions of enablers/barriers and suggested improvements to the approach will be examined. Resources at each stage will be traced to determine the economic implications of implementing the MoC and costed from health system perspective. Primary outcomes: increase in number of index cases clinically identified; reduction in low-density lipoprotein cholesterol of treated cases. Secondary outcomes: increase in the number of family cases detected/contacted; cost implications of the MoC. Ethics and dissemination: Study approval by The University of Notre Dame Australia Human Research Ethics Committee Protocol ID: 0 16 067F. Registration: Australian New Zealand Clinical Trials Registry ID: 12616000630415. Information will be disseminated via research seminars, conference presentations, journal articles, media releases and community forums

The Student Movement Volume 107 Issue 21: Evensong Vespers Honors President Luxton\u27s Gift of Service

HUMANS Apple vs Android, Grace No Senior Plans, Interviewed by: Solana Campbell Student Workers: Claudia Ruiz, Interviewed by: Nora Martin ARTS & ENTERTAINMENT WAUS: An Update on our Beloved Campus Radio Station, Grace No Creatives on Campus: Mateo Banks, Grace No Meditation for the Easter Season: Community Celebrates President Luxton, Lily Burke and Alannah Tjhatra NEWS A Night of Avant-Garde, Solana Campbell Environmental Events Bring Awareness to Berrien County, Andrew Francis Interview with Dr. Heather Thompson Day: Becoming an Author and Inspiring Change, Brendan Oh The Living Library: Stories from the Andrews Community, Isabella Koh IDEAS Enough with the Self Help Books, Valerie Akinyi Social Media and Authenticity, Nathaniel Reid The Resurgence of the Jim Crow Era in America, Shania Watts PULSE At Home at Andrews University, Elizabeth Dovich Sex Education in Adventist Institutions, Lexie Dunham The Importance of the Office of Culture and Inclusion, Zothile Sibanda LAST WORD Last Word, Solana Campbellhttps://digitalcommons.andrews.edu/sm-107/1020/thumbnail.jp

The Student Movement Volume 106 Issue 14: Climb Every Mountain, Tube Every Hill

HUMANS Getting to Know AU\u27s New Photography Professor Dan Weber. Interviewed by Karenna Lee Interview with BSCF President Khaylee Sands, Interviewed by: Timmy Duado Military to Music: Interview with Marcus Carter, Interviewed by: Grace No ARTS & ENTERTAINMENT Black Entertainers Who Inspire Me, Hannah Cruse In the Words of AU: Why Black Art is Important, Solana Campbell Know Your Roots by Marcel Mattox, Interviewed by: Kaela McFadden NEWS Embracing the New Normal, Jenae Rogers Mask Off: Andrews University Updates Covid-19 Guidelines, Abigail Lee Panic: Understanding the War Over Ukraine, Chris Ngugi Winter Storms Flurry Through the Midwest and the South, Nathan Mathieu IDEAS Kanye West and Paternal Accountability: Why it Matter, Alyssa Henriquez Should Joe Biden Cancel Student Debt? Who Has to Save The World?, Qualyn Robinson PULSE Cardinals vs. Golden Eagles: A Few Last Flights at the Season\u27s End, Alannah Tjhatra Fun Weekend Winter Activities, Shania Watts Thoughts on the Beijing 2022 Winter Olympics, Kaela McFadden THE LAST WORD Please Lamson Hall, Can I Have Some More?, Abigail Leehttps://digitalcommons.andrews.edu/sm-106/1013/thumbnail.jp

SOD2 Deficiency in Cardiomyocytes Defines Defective Mitochondrial Bioenergetics as a Cause of Lethal Dilated Cardiomyopathy

Electrophilic aldehyde (4-hydroxynonenal; 4-HNE), formed after lipid peroxidation, is a mediator of mitochondrial dysfunction and implicated in both the pathogenesis and the progression of cardiovascular disease. Manganese superoxide dismutase (MnSOD), a nuclear-encoded antioxidant enzyme, catalyzes the dismutation of superoxide radicals (O2•-) in mitochondria. To study the role of MnSOD in the myocardium, we generated a cardiomyocyte-specific SOD2 (SOD2Δ) deficient mouse strain. Unlike global SOD2 knockout mice, SOD2Δ mice reached adolescence; however, they die at ~4 months of age due to heart failure. Ultrastructural analysis of SOD2Δ hearts revealed altered mitochondrial architecture, with prominent disruption of the cristae and vacuole formation. Noninvasive echocardiographic measurements in SOD2Δ mice showed dilated cardiomyopathic features such as decreased ejection fraction and fractional shortening along with increased left ventricular internal diameter. An increased incidence of ventricular tachycardia was observed during electrophysiological studies of the heart in SOD2Δ mice. Oxidative phosphorylation (OXPHOS) measurement using a Seahorse XF analyzer in SOD2Δ neonatal cardiomyocytes and adult cardiac mitochondria displayed reduced O2 consumption, particularly during basal conditions and after the addition of FCCP (H+ ionophore/uncoupler), compared to that in SOD2fl hearts. Measurement of extracellular acidification (ECAR) to examine glycolysis in these cells showed a pattern precisely opposite that of the oxygen consumption rate (OCR) among SOD2Δ mice compared to their SOD2fl littermates. Analysis of the activity of the electron transport chain complex identified a reduction in Complex I and Complex V activity in SOD2Δ compared to SOD2fl mice. We demonstrated that a deficiency of SOD2 increases reactive oxygen species (ROS), leading to subsequent overproduction of 4-HNE inside mitochondria. Mechanistically, proteins in the mitochondrial respiratory chain complex and TCA cycle (NDUFS2, SDHA, ATP5B, and DLD) were the target of 4-HNE adduction in SOD2Δ hearts. Our findings suggest that the SOD2 mediated 4-HNE signaling nexus may play an important role in cardiomyopathy

The Student Movement Volume 107 Issue 18: Ain\u27t I A Woman? : AU Students Reflect on the Feminist Movement

HUMANS Interview with the WEAAU President, Interviewed by: Grace No What is Feminism to You?, Interviewed by: Caryn Cruz What\u27s Your Major?, Interviewed by: Nora Martin ARTS & ENTERTAINMENT Currently: The Idol, Solana Campbell Faculty Art Exhibition, Ysabelle Fernando Music Seniors: A Day in the Life, Aiko J. Ayala Rios Through the Paintings, Kaela McFadden NEWS Empowering our Neighbors: Interview with H.E.L.P. Program Director Carlisle Suttton, Isabella Koh John Wesley Taylor V Elected to be the Next Andrews University President Students Open the Month with Cultural Showcase, Andrew Francis The Agora at AU: A Conversation on Police Brutality, Solana Campbell What\u27s Going on East Palestine, Ohio?, Julia Randall IDEAS The Biblical Bechdel: How Much are Women Represented in the Bible?, Bella Hamann The Murder of Abby Choi: A Spotlight on Relationship Violence Against Women, Abby Shim PULSE Nilah Mataafa: An End to Period Poverty, Interviewed by: Chris Ngugi Remember the Ladies! : The Female Perspective on Women\u27s History Month, Amelia Stefanescu The Aerial Workout You\u27ve Never Heard Of, Melissa Moore LAST WORD Perfect Imperfections, Shania Wattshttps://digitalcommons.andrews.edu/sm-107/1017/thumbnail.jp

Access, acceptance and adherence to cancer prehabilitation: a mixed-methods systematic review

Purpose The purpose of this systematic review is to better understand access to, acceptance of and adherence to cancer prehabilitation. Methods MEDLINE, CINAHL, PsychINFO, Embase, Physiotherapy Evidence Database, ProQuest Medical Library, Cochrane Library, Web of Science and grey literature were systematically searched for quantitative, qualitative and mixed-methods studies published in English between January 2017 and June 2023. Screening, data extraction and critical appraisal were conducted by two reviewers independently using Covidence™ systematic review software. Data were analysed and synthesised thematically to address the question ‘What do we know about access, acceptance and adherence to cancer prehabilitation, particularly among socially deprived and minority ethnic groups?’ The protocol is published on PROSPERO CRD42023403776 Results Searches identified 11,715 records, and 56 studies of variable methodological quality were included: 32 quantitative, 15 qualitative and nine mixed-methods. Analysis identified facilitators and barriers at individual and structural levels, and with interpersonal connections important for prehabilitation access, acceptance and adherence. No study reported analysis of facilitators and barriers to prehabilitation specific to people from ethnic minority communities. One study described health literacy as a barrier to access for people from socioeconomically deprived communities. Conclusions There is limited empirical research of barriers and facilitators to inform improvement in equity of access to cancer prehabilitation