38,612 research outputs found
Noise suppression characteristics of peripherally segmented duct liners
The acoustic fields and transmission losses produced in semi-infinite circular ducts with peripherally segmented liners are analyzed using a series expansion of hard-wall duct modes. The coefficients of the series are computed using Galerkin's method. Unlike finite element approaches, this analysis includes the effects of realistic sources and the number of peripheral strips need not be small. It is shown that peripherally segmented liners redistribute the acoustic energy in waves composed of only a single circumferential mode at the source into other waves which contain a multitude of circumferential modes in the lined section. The accuracy of eigenfunctions computed from the analysis was observed to increase as either the frequency or radial mode order increased. The transmission losses were found to be accurate at frequencies above the cut-on value of the first-order radial mode in a hard-wall duct. The results show that for plane wave sources, peripherally segmented liners may attenuate as much sound as an optimized uniform liner at the optimal point while giving more noise suppression at most other frequencies
A method for determining acoustic-liner admittance in ducts with sheared flow in two-cross-sectional directions
A method is developed for determining the acoustic admittance of a test liner installed in the wall of a grazing flow impedance tube. The mean flow is permitted flow gradients in both cross-sectional directions of the tube. The unknown admittance value is obtained by solving an eigenvalue problem. This eigenvalue problem results from the application of the finite-element method to the partial differential equation and boundary conditions governing the acoustic field. The credibility of the method is established by comparing results with exact solutions obtained for a constant mean-flow profile and with previous results for cases involving shear in only one cross-sectional direction. Excellent comparisons are obtained in both cases. The analysis is used in conjunction with a limited amount of experimental data and shows that the flow must be accurately modeled in order to determine the acoustic-liner properties
A new method for determining acoustic-liner admittance in a rectangular duct with grazing flow from experimental data
A method is developed for determining acoustic liner admittance in a rectangular duct with grazing flow. The axial propagation constant, cross mode order, and mean flow profile is measured. These measured data are then input into an analytical program which determines the unknown admittance value. The analytical program is based upon a finite element discretization of the acoustic field and a reposing of the unknown admittance value as a linear eigenvalue problem on the admittance value. Gaussian elimination is employed to solve this eigenvalue problem. The method used is extendable to grazing flows with boundary layers in both transverse directions of an impedance tube (or duct). Predicted admittance values are compared both with exact values that can be obtained for uniform mean flow profiles and with those from a Runge Kutta integration technique for cases involving a one dimensional boundary layer
Assessment of Axial Wave Number and Mean Flow Uncertainty on Acoustic Liner Impedance Eduction
International audienceA key parameter in designing and assessing advanced broadband acoustic liners to achieve the current and future noise reduction goals is the acoustic impedance presented by the liner. This parameter, intrinsic to a specific liner configuration, is dependent on sound pressure level and grazing flow velocity. Current impedance eduction approaches have, in general, provided excellent results and continue to be employed throughout the acoustic liner community. However, some recent applications have indicated a possible dependence of the educed impedance on the direction of incident waves relative to the mean flow. The purpose of the current study is to investigate this unexpected behavior for various impedance eduction methods based on the Pridmore-Brown and convected Helmholtz equations. Specifically, the effects of flow profile and axial wavenumber uncertainties on educed impedances for upstream and downstream sources are investigated. The uniform flow results demonstrate the importance of setting a correct Mach number value in obtaining consistent educed impedances for upstream and downstream sources. In fact, the consistency of results over the two source locations was greatly improved by a slight modification of the uniform flow Mach number. In addition, uncertainty in educed axial wavenumber was also illustrated to correlate well with differences in the educed impedances, even with modified uniform flow Mach number. Finally, while less straightforward than in the uniform flow case, it appears that modification of the mean flow profile may also improve consistency of results for upstream and downstream results when shear flow is included
A new method for the inversion of atmospheric parameters of A/Am stars
We present an automated procedure that derives simultaneously the effective
temperature , the surface gravity logg, the metallicity [Fe/H], and
the equatorial projected rotational velocity vsini for "normal" A and Am stars.
The procedure is based on the principal component analysis inversion method of
Paletou et al. (2015a). A sample of 322 high resolution spectra of F0-B9 stars,
retrieved from the Polarbase, SOPHIE, and ELODIE databases, were used to test
this technique with real data. We have selected the spectral region from
4400-5000\AA\ as it contains many metallic lines and the Balmer H line.
Using 3 datasets at resolving powers of R=42000, 65000 and 76000, about
6.6x synthetic spectra were calculated to build a large learning
database. The Online Power Iteration algorithm was applied to these learning
datasets to estimate the principal components (PC). The projection of spectra
onto the few PCs offered an efficient comparison metric in a low dimensional
space. The spectra of the well known A0- and A1-type stars, Vega and Sirius A,
were used as control spectra in the three databases. Spectra of other well
known A-type stars were also employed in order to characterize the accuracy of
the inversion technique. All observational spectra were inverted and
atmospheric parameters derived. After removal of a few outliers, the
PCA-inversion method appears to be very efficient in determining ,
[Fe/H], and vsini for A/Am stars. The derived parameters agree very well with
previous determinations. Using a statistical approach, deviations of around 150
K, 0.35 dex, 0.15 dex, and 2 km/s were found for , logg, [Fe/H], and
vsini with respect to literature values for A-type stars. The PCA-inversion
proves to be a very fast, practical, and reliable tool for estimating stellar
parameters of FGK and A stars, and deriving effective temperatures of M stars.Comment: 16 pages, 9 figures. Accepted in A&
Human platelet activation by Escherichia coli: roles for FcγRIIA and integrin αIIbβ3
Gram-negative Escherichia coli cause diseases such as sepsis and hemolytic uremic syndrome in which thrombotic disorders can be found. Direct platelet–bacterium interactions might contribute to some of these conditions; however, mechanisms of human platelet activation by E. coli leading to thrombus formation are poorly understood. While the IgG receptor FcγRIIA has a key role in platelet response to various Gram-positive species, its role in activation to Gram-negative bacteria is poorly defined. This study aimed to investigate the molecular mechanisms of human platelet activation by E. coli, including the potential role of FcγRIIA. Using light-transmission aggregometry, measurements of ATP release and tyrosine-phosphorylation, we investigated the ability of two E. coli clinical isolates to activate platelets in plasma, in the presence or absence of specific receptors and signaling inhibitors. Aggregation assays with washed platelets supplemented with IgGs were performed to evaluate the requirement of this plasma component in activation. We found a critical role for the immune receptor FcγRIIA, αIIbβ3, and Src and Syk tyrosine kinases in platelet activation in response to E. coli. IgG and αIIbβ3 engagement was required for FcγRIIA activation. Moreover, feedback mediators adenosine 5’-diphosphate (ADP) and thromboxane A₂ (TxA₂) were essential for platelet aggregation. These findings suggest that human platelet responses to E. coli isolates are similar to those induced by Gram-positive organisms. Our observations support the existence of a central FcγRIIA-mediated pathway by which human platelets respond to both Gram-negative and Gram-positive bacteria
Materials technology assessment for stirling engines
A materials technology assessment of high temperature components in the improved (metal) and advanced (ceramic) Stirling engines was undertaken to evaluate the current state-of-the-art of metals and ceramics, identify materials research and development required to support the development of automotive Stirling engines, and to recommend materials technology programs to assure material readiness concurrent with engine system development programs. The most critical component for each engine is identified and some of the material problem areas are discussed
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Titanocene anticancer complexes and their binding mode of action to human serum albumin: a computational study
Due to the pivotal role played by human serum albumin (HSA) in the transport and cytotoxicity of titanocene complexes, a docking study has been performed on a selected set of titanocene complexes to aid in the current understanding of the potential mode of action of these titanocenes upon binding HSA. Analysis of the docking results has revealed potential binding at the known drug binding sites in HSA and has provided some explanation for the specificity and subsequent cytotoxicity of these titanocenes. Additionally, a new alternative binding site for these titanocenes has been postulated
An assessment of an F2 or N2O4 atmospheric injection from an aborted space shuttle mission
Assuming a linear relationship between the stratosphere loading of NOx and the magnitude of the ozone perturbation, the change in ozone expected to result from space shuttle ejection of N2O4 was calculated based on the ozone change that is predicted for the (much greater) NOx input that would accompany large-scale operations of SSTs. Stratospheric fluorine reactions were critically reviewed to evaluate the magnitude of fluorine induced ozone destruction relative to the reduction that would be caused by addition of an equal amount of chlorine. The predicted effect on stratospheric ozone is vanishingly small
Evaluation of a Multizone Impedance Eduction Method
A computational study is used to evaluate the PyCHE impedance eduction method developed at the NASA Langley Research Center. This method combines an aeroacoustic duct propagation code based on numerical solution to the convected Helmholtz equation with a global optimizer that uses the Differential Evolution algorithm. The efficacy of this method is evaluated with acoustic pressure data simulated to represent that measured with one-zone, two-zone, and three-zone liners mounted in the NASA Langley Grazing Flow Impedance Tube. The PyCHE method has a normalized impedance error of approximately 0.2 for (uniform) one-zone liners with a length of at least 5, and produces quite reasonable results for liners as short as 2. Whereas the impedance of the liner has an effect on eduction accuracy, the amount of attenuation is shown to be the dominant parameter. Similar results are observed for two-zone liners, for which the impedance of each zone is unique. The two-zone results also indicate it is more difficult to accurately educe resistance than reactance, and a zone length of at least 6 (slightly longer than for uniform liners) is needed to limit the normalized error to 0.2. The PyCHE method is also demonstrated to successfully educe the impedances for each zone of a three-zone liner. These results are sufficiently encouraging to warrant the continued usage of the PyCHE impedance eduction method for single and multizone liners
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