10 research outputs found
Estudo de roteirização de veículos para distribuição de carga em Santa Catarina
- Author
- Publication venue
- Florianópolis, SC
- Publication date
- 24/11/2016
- Field of study
TCC (graduação) - Universidade Federal de Santa Catarina. Centro Tecnológico. Engenharia Civil.O presente trabalho pretende analisar a distribuição de carga de uma empresa hipotética, com o apoio de funcionalidades específicas de um sistema de informações geográficas. Esta ferramenta foi aplicada para a resolução de um Problema de Roteirização e Programação de Veículos com Janela de Tempo (PRPVJT), que é caracterizado por possuir uma frota de veículos homogênea e clientes com demandas determinísticas. Inicialmente é feita uma revisão de literatura sobre o transporte rodoviário de cargas, sobre os grafos, que constituem o embasamento teórico do problema, sobre os sistemas de informações geográficas, que representam a ferramenta utilizada, sobre o custo do transporte rodoviário, que faz parte da solução do problema, e sobre os problemas de roteirização de veículos. Em seguida é feita a caracterização do problema, além de apresentar um procedimento para a modelagem da área de estudo e de apresentar a ferramenta utilizada. Como resultados são apresentadas as rotas otimizadas segundo o critério de menor tempo de percurso, o dimensionamento da frota de veículos e os custos operacionais de cada veículo. Após gerados, os resultados são comparados com dados de volumes médios diários das rodovias para fins de validação
Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial
- Author
- Abaterusso Cataldo
- Abdul Kadir Khalid
- Abrahamovych Orest
- Acharya Shamasunder
- Acosta Idalia
- Adam Noor
- Adams Luthando
- Adawi Faiad
- Adolphe Allen
- Ahmad Ghazali
- Ahmed Azazuddin
- Ahmed Ziauddin
- Ahn Kyu Jeung
- Alcantara-Gonzalez Altagracia Aurora
- Aldrete Jorge
- Ali Norhaliza Mohd
- Almirall Jaume
- Alscher Mark
- Alvarado Odilon
- Alvarez German
- Alvarisqueta Andres
- Amin Mohammad
- Amodeo Celso
- Andress Dennis L
- Annand Andrew
- Antunes Ferreira Manuel Anibal
- Anzai Jiichi
- Apostolou Theofanis
- Arauz-Pacheco Carlos
- Arciszewska Malgorzata
- Argoud Georges
- Arif Ahmed
- Aronson Ronnie
- Arrieta Lezama Javier
- Assefi Ali
- Ato Keita
- Atray Naveen
- Awua-Larbi Stella
- Aziz Nor Azizah
- Azuma Nobuyuki
- Bai Liqun
- Bailey Gordon
- Bajaj Harpreet Singh
- Bakdash Wa'El
- Baker John
- Baker Penelope
- Bako Gabriel
- Bakris George
- Bakris George
- Bansal Shweta
- Bar-Dayan Yosefa
- Bardymova Tatiana
- Barendregt Jnm
- Barengolts Elena
- Bartaskova Dagmar
- Bau Cho-Tsan
- Bayliss George
- Beddhu Srinivasan
- Bedros Fadi
- Belledonne Mario
- Belo Diogo
- Bentsianov Marie
- Bhargava Anuj
- Bhorat Qasim
- Bieler Tasso
- Birne Rita
- Blagoveshchenskaya Olga
- Bloom Scott
- Blumenthal Samuel
- Bochicchio-Ricardelli Tomasso
- Bock Andreas
- Bohm Guillermo
- Boiskin Mark
- Bonet Sol Josep
- Borges Joao Lindolfo
- Bowman-Stroud Cynthia
- Brantley Roman
- Bressler Peter
- Brown Eric
- Brunati Chiara
- Brusco Osvaldo
- Bucek Petr
- Budde Klemens
- Burga Nunez Jose
- Burgos-Calderon Rafael
- Busch Robert
- Butt Salman
- Cabrita Antonio
- Calderon Ortiz Ricardo
- Calderon Ticona Jorge
- Calero Gonzalez Francesca
- Cangiano Jose
- Capasso Giovambattista
- Carranza-Madrigal Jaime
- Castillo Alvaro
- Castro-Alonso Cristina
- Cathcart Harold
- Cercato Cintia
- Cha Dae-Ryong
- Chan Doris
- Chatha Rupi
- Chen Ching-Chu
- Chen Jung-Fu
- Chen Nan
- Cheung Siu Fai
- Chevaile-Ramos Jose
- Chew Wong Alfredo
- Chmelickova Hana
- Cho Ho Chan
- Cho Yong-Wook
- Choi Kyung Mook
- Choi Moon-Gi
- Chow Stephen
- Christofides Elena
- Chu Chih-Hsun
- Chuang Peale
- Chung Choon Hee
- Ciechanowski Kazimierz
- Cigarran Guldris Secundino
- Coetzee Kathleen
- Cohen Josef
- Combe Christian
- Comulada-Rivera Angel
- Conte Giuseppe
- Cooke Duncan
- Correa-Rotter Ricardo
- Costa e Forti Adriana
- Cournoyer Serge
- Cruz Lucita
- Cusumano Ana
- D'Avila Domingos
- Dahl Neera
- Danin Vargas Alfredo
- Daoud Deeb
- Davis Tim
- de Arteaga Javier
- De Cosmo Salvatore
- De la Calle Gilda
- de Lourdes Noronha Irene
- de Zeeuw Dick
- Deboni Luciane
- Delgado-Butron Cesar
- Dellanna Frank
- Desai Sachin
- Dextre Espinoza Augusto
- Ding Guohua
- Ding Xiaoqiang
- Distiller Larry
- Dixon Brad
- Doo-Man Kim
- Doshi Ankur
- Draibe Sergio
- Dudar Iryna
- Dulude Emily
- Duma Livia
- Dussol Bertrand
- Egido Jesus
- Egstrup Kenneth
- El-Shahawy Mohamed
- Elbert Alicia
- Elder John
- Eliaschewitz Freddy
- Ellis Graham
- Endre Zoltan
- Esnault Vincent
- Esposito Ciro
- Essaian Ashot
- Eustace Joseph
- Fang Michael
- Farfan-Aspilcueta Julio
- Farias Eduardo
- Fekete Jozef
- Felicio Joao
- Fellstrom Bengt
- Fernandez Fresnedo Gema
- Fernandez Giraldez Elvira
- Fernando Ronald
- Fitz-Patrick David
- Flores Jose
- Foo Marjorie Wai Yin
- Fraenkel Margaret
- Fraige Filho Fadlo
- Frajewicki Victor
- Frias Juan
- Fried Linda
- Fu Ping
- Fu Shuxia
- Fujii Shinya
- Fujita Akira
- Fulopova Alla
- Fung Samuel
- Fung Yin Khet
- Furuya Ryuichi
- Fushtey Ivan
- Galan Antonio
- Galfre Andrea
- Galindo Ramos Eugenia
- Gallagher Martin
- Galphin Claude
- Galushchak Olga
- Gansevoort Ronald
- Gaona Raul
- Garcia Mendez Isabel
- Gesualdo Loreto
- Gilbert John
- Gillard Pieter
- Gnudi Luigi
- Godoy Gonzalo
- Goh Bak Leong
- Goldfarb David
- Golestaneh Laden
- Goluch Richard
- Gonzalez Gonzalez Jose
- Gonzalez Fernando
- Gonzalez-Galvez Guillermo
- Goto Daisuke
- Gouge Steven
- Goumenos Dimitrios
- Graf Ronald
- Greenwood Gregory
- Greloni Gustavo
- Guadiz Ramon
- Guasch Antonio
- Gundroo Aijaz
- Guo Xiaohui
- Gutierrez Vicente
- Halimi Jean-Michel
- Hall Karen
- Hames Melanie
- Hancu Nicolae
- Hanson Lenita
- Hao Chuanming
- Harada Hiroyuki
- Hashiguchi Yasuhiro
- Hassan Wan Hasnul Halimi Wan
- Hasslacher Christoph
- Heerspink Hiddo J L
- Hellberg Olof
- Herman Lee
- Hernandez-Jaras Julio
- Herrada Orue Benjamin
- Herrero Calvo Jose
- Hershon Kenneth
- Hirano Fuminori
- Honova Vaclava
- Horwitz Edward
- Hou Fan-Fan
- Hou Fanfan
- Hougardy Jean
- Huang Chien-Ning
- Hugo Christian
- Hussein Zanariah
- Iehara Noriyuki
- Iitsuka Tadashi
- Ijaz Adeel
- Ikeda Naoko
- Imura Mitsuo
- Inoue Toshihiko
- Ionutiu Lavinia
- Ishikawa Kazuo
- Ishiko Tamayo
- Israel Ezra
- Itabashi Naoki
- Ivanova Svetlana
- Iwaoka Hideaki
- Jabbour Serge
- Jadoul Michel
- Jamal Aamir
- James Sam
- Jang Hak Chul
- Jardula Michael
- Jere Charles
- Ji Linong
- Jia Weiping
- Jiang Ju-Ying
- John Rekha
- Jolly Shivinder
- Jones Audrey
- Joshi Sucharit
- Joshi Sudhir
- Juncos Luis
- Kalender Betul
- Kalirao Paramjit
- Kalra Phillip
- Kanai Hidetoshi
- Kaneko Shizuka
- Kantola Ilkka
- Kantor Samuel
- Karim Shahana
- Karonova Tatiana
- Karpova Irina
- Kashihara Naoki
- Kashine Susumu
- Kayali Zeid
- Keitel Elizete
- Kenis Irina
- Khandwala Hasnain
- Kim Beom Seok
- Kim Byung-Joon
- Kim In-Joo
- Kim Min Seon
- Kim Sang Yong
- Kim Sin-Gon
- Kishimoto Rui
- Kitzman Dalane W
- Kiyosue Arihiro
- Klimontov Vadim
- Klodawska Katarzyna
- Knobler Hilla
- Kobayashi Kunihisa
- Kohan Donald
- Kolenyk Mykola
- Kolesarova Eva
- Kolmakova Elena
- Kon Sui Phin
- Kopyt Nelson
- Korpachev Vadym
- Kosch Christine
- Kostynenko Tetyana
- Kosuge Keiichiro
- Kovesdy Csaba
- Koziolova Natalya
- Kronfli Saeed
- Kumar Jayant
- Kuskalo Petro
- Kuzin Anatoly
- Lahtela Jorma
- Lalwani Tarik
- Lantseva Olga
- Lauro Davide
- Laverman Gozewijn
- Lavin Peter
- Lawrence Mary
- Lee Hyoung Woo
- Lee Jae Hyuk
- Lee Joseph
- Lee Kang-Wook
- Lee Kwan Woo
- Lee Moon-Kyu
- Lee Sang Ah
- Leguizamo-Dimas Aniceto
- Legun Oleg
- Leite Silmara
- Leon-Forero Carlos
- Levin Ellis
- Levine Andrew
- Li Yuxiu
- Liakopoulos Vasilios
- Liberanskaya Natalia
- Lien Yeong-Hau
- Liew Adrian
- Lin Ching-Ling
- Link Michael
- Liss Kenneth
- Liu Bicheng
- Liu Zhangsuo
- Lui Sing Leung
- Luik Peter
- Lunt Helen
- Luo Qun
- Macisaac Richard
- Maddukuri Geetha
- Madero Rovalo Magdalena
- Madu Ivy-Joan
- Maeda Hajime
- Maeda Yoshitaka
- Maffei Laura
- Makan Hemant
- Makino Hirofumi
- Makino Shinya
- Makita Yuichiro
- Maksudova Adelya
- Malberti Fabio
- Mangoo-Karim Roberto
- Mankovskyy Borys
- Manley John
- Marasaev Vyacheslav
- Marder Bradley
- Marino Francesco
- Mark Patrick
- Markell Mariana
- Marques Vidas Maria
- Martins Munoz Judith
- Martynenko Vladimir
- Martynyuk Liliya
- Matsuda Hirofumi
- Matsuhisa Munehide
- Matsutani Akira
- Matta Fontanet Evelyn
- Mavromatidis Konstantinos
- Maxwell Peter
- Mayer Gert
- Mazur Stanislaw
- Mcfadden Christopher
- Mcmurray John J V
- Medina-Santander Boris
- Melish John
- Melnick Joel Z
- Menefee Judson
- Merican Nor Shaffinaz Yusuf Azmi
- Mersey James
- Milagres Rosangela
- Miller Alan
- Miller Michael G
- Miller Steven
- Minasian Raffi
- Minga Todd
- Minguela Pesquera Jose Ignacio
- Mistodie Cristina
- Mitha Essack
- Miyaoka Hiroaki
- Mohamed Mafauzy
- Mok Ji Oh
- Molas Coten Jose Ramon
- Montero Manuel
- Montero Nuria
- Mordovin Viktor
- Moura Neto Jose Andrade
- Moya Hechevarria Jaynier
- Muehlfeld Anja
- Mukasa Koji
- Mulloy Laura
- Munoz Rodrigo
- Muoneke Rosemary
- Nagai Sou
- Nagayama Koji
- Naiker Puvenesvari
- Naka Motoji
- Nakamura Takehiro
- Nakashima Eitaro
- Nakazawa Jun
- Nakhle Samer
- Nam-Goong Il-Seong
- Nammour Michael
- Nappi Felice
- Navarro Gonzalez Juan
- Nazeer Imran
- Necki Miroslaw
- Nesrallah Gihad
- Newman George
- Ni Zhaohui
- Nica Romanita
- Nik Ahmad Nik Nur Fatnoon
- Nimura Toshinori
- Nino-Cruz Jose
- Nishimura Motonobu
- Nowicki Michal
- O'Shaughnessy Andrew
- O'Shea Donal
- Obetkova Ida
- Oczachowska-Kulik Anna
- Oh Tae Keun
- Okamoto Hideki
- Oksa Adrian
- Onishi Yukiko
- Ono Keiko
- Ono Yasuhiro
- Oplustilova Alexandra
- Oroszova Aniko
- Osama Sayed
- Osonoi Takeshi
- Ostergaard Ove
- Ozaki Risa
- Panichi Vincenzo
- Panina Svitlana
- Park Kyong-Soo
- Park Tae-Sun
- Parving Hans-Henrik
- Paschoalin Raphael
- Pascual Julio
- Passadakis Ploumis
- Patel Dipesh
- Pavlova Maria
- Pecoits Filho Roberto
- Peguero-Rivera Alfredo
- Pei Dee
- Pergola Pablo
- Pergola Pablo E
- Perkovic Vlado
- Perlman Alan
- Petit Catherine
- Petr Martin
- Petrica Ligia
- Petrosyan Olena
- Phillips Lawrence
- Pichette Vincent
- Pikalova Natalia
- Pilmore Helen
- Pintilei Ella
- Pistrosch Frank
- Pollock Carol
- Pontoriero Giuseppe
- Popenda Grazyna
- Povlsen Johan
- Powell Thomas
- Praga Terente Manuel
- Prager Rudolf
- Prieto Velasco Mario
- Prompt Carlos Alberto
- Pugliese Giuseppe
- Punt Zelda
- Quesada-Suarez Luis
- Rabbat Christian
- Rabindranath Kannaiyan
- Ramlachan Padaruth
- Ramos Aura
- Rampino Teresa
- Raslova Katarina
- Rassi Nelson
- Rastogi Anjay
- Ravera Maura
- Rechkova Elena
- Reichel Ronald
- Reisin Efrain
- Rendell Marc
- Renoirte Lopez Karina
- Rico Hernandez Raul
- Riella Miguel Carlos
- Robey Brooks
- Rodriguez-Perez Jose
- Roger Simon
- Rombola Giuseppe
- Ropero-Cartier Armando
- Rosado Carlos
- Rosenberger Jaroslav
- Rossing Peter
- Roy Louise
- Ruggenenti Piero
- Russo Domenico
- Rychlik Ivan
- Saba Fadi
- Sakai Takashi
- Sakhrani Lakhi
- Salles Joao
- Samoylova Yulia
- Santamaria Olmo Rafael
- Santoro Domenico
- Santos Canani Luis
- Santos Juan
- Sari Ramazan
- Sasaki Hiromitsu
- Sasaki Nobuhiro
- Satman Ilhan
- Sato Nobuyuki
- Sato Toshiaki
- Sato Yuichi
- Sauque Reyna Leobardo
- Savin Virginia
- Sayfutdinov Rustam
- Schenkenberger Isabelle
- Schmidt Alice
- Schmidt Rebecca
- Schmidt-Guertler Hans
- Scott David
- Segiet Thomas
- Sekikawa Takashi
- Sensenbrenner John
- Seo Ji A
- Seron Daniel
- Sezer Siren
- Shahid Newman
- Shamkhalova Minara
- Shaw Sylvia
- Sheu Wayne
- Shi Bingyin
- Shi Wei
- Shibagaki Yugo
- Shin Mijung
- Shinoda Junji
- Shon Ho Sang
- Shvarts Yuri
- Siamopoulos Konstantinos
- Sigitova Olga
- Simon Eric
- Skokowska Ewa
- Sligh Teresa
- Sloan Lance
- Slover Judith
- Smak Gregoor Peter
- Smolko Peter
- Smolyarchuk Elena
- Solomon Richard
- Solovev Oleg
- Soto Gonzalez Alfonso
- Sreenan Seamus
- Stack Austin
- Stanislavchuk Mykola
- Stefanidis Ioannis
- Stoica George
- Strand Jorma
- Stranks Stephen
- Stryzhak Vasyl
- Su Benli
- Suh Sung Hwan
- Sukor Norlela
- Sun Shiren
- Suranyi Michael
- Suzuki Katsunori
- Szerlip Harold
- Tadika Takenobu
- Takeda Tetsuro
- Taliercio John
- Tam Paul
- Tan Kathryn
- Tanaka Tsuyoshi
- Tanaka Yukio
- Tang Sydney
- Tarkan Joshua
- Taya Noriyasu
- Tentolouris Nikolaos
- Teo Boon Wee
- Tesar Vladimir
- Thakar Charuhas
- Thomson Stephen
- Tien Kai-Jen
- Tietjen David
- Timar Romulus
- Tindall Hilary
- Tkac Ivan
- Tkach Sergii
- Tobe Sheldon
- Tobe Sheldon
- Tokui Mikiya
- Tomilina Natalia
- Topchii Ivan
- Toussaint Nigel
- Trokis Julien
- Tseng Shih-Ting
- Tsuchida Kenichi
- Tsujimoto Tetsuro
- Tsutsui Masahiro
- Tulloch Brian
- Tuta Liliana
- Tutescu Adriana
- Ueda Shinichiro
- Ujihara Makoto
- Umayahara Yutaka
- Urena Torres Pablo
- Vaithilingam Indralingam
- Valera Cortes Ildefonso
- Vallejos Augusto
- Van Vlem Bruno
- Van Zyl Louis
- Vargas-Gonzales Rolando
- Varghese Freemu
- Vazquez-Tanus Jose
- Vengadasalam V Paranthaman P
- Vercammen Chris
- Vicks Steven
- Vielhauer Volker
- Vijayasingham Shalini
- Villevalde Svetlana
- Vogel Daniel
- Vogt Liffert
- Wainstein Julio
- Wang Song
- Wanner Christoph
- Warling Xavier
- Watanabe Shuichi
- Weinstein Debra
- Weinstein Talia
- Weiss Robert
- Weng Jian
- Whaley-Connell Adam
- Wiecek Andrzej
- Wigderson Melissa
- Wise Jonathan
- Wong Hin Seng
- Woo Jeong-Taek
- Wruk Michal
- Wu Du-An
- Wu Mai-Szu
- Xiao Guanqing
- Xing Changying
- Xu Gang
- Xu Yan
- Yagil Yoram
- Yalcin Murat
- Yamada Daishiro
- Yamaguchi Yukinari
- Yamamoto Masahiro
- Yamauchi Akira
- Yambe Yuko
- Yang Jinkui
- Yavdosyuk Andrey
- Yeoh Lee Ying
- Yeung Vincent
- Yi Joo Hark
- Yi Tingting
- Yildiz Alaattin
- Yoo Soon-Jib
- Yoon Kun Ho
- Yoon Sun Ae
- Youmbissi Joseph
- Yu Shengqiang
- Yu Tae Yang
- Zahumensky Emil
- Zanella Maria
- Zaoui Philippe
- Zapata-Rincon Luis
- Zea-Nunez Carlos Antonio
- Zeig Steven
- Zhao Hongwen
- Zhao Jiajun
- Zhao Minghui
- Zieve Franklin
- Zolotaikina Viktoriia
- Zrazhevskiy Konstantin
- Zucchini Alfredo
- Zuo Li
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
Background: Short-term treatment for people with type 2 diabetes using a low dose of the selective endothelin A receptor antagonist atrasentan reduces albuminuria without causing significant sodium retention. We report the long-term effects of treatment with atrasentan on major renal outcomes. Methods: We did this double-blind, randomised, placebo-controlled trial at 689 sites in 41 countries. We enrolled adults aged 18–85 years with type 2 diabetes, estimated glomerular filtration rate (eGFR)25–75 mL/min per 1·73 m 2 of body surface area, and a urine albumin-to-creatinine ratio (UACR)of 300–5000 mg/g who had received maximum labelled or tolerated renin–angiotensin system inhibition for at least 4 weeks. Participants were given atrasentan 0·75 mg orally daily during an enrichment period before random group assignment. Those with a UACR decrease of at least 30% with no substantial fluid retention during the enrichment period (responders)were included in the double-blind treatment period. Responders were randomly assigned to receive either atrasentan 0·75 mg orally daily or placebo. All patients and investigators were masked to treatment assignment. The primary endpoint was a composite of doubling of serum creatinine (sustained for ≥30 days)or end-stage kidney disease (eGFR <15 mL/min per 1·73 m 2 sustained for ≥90 days, chronic dialysis for ≥90 days, kidney transplantation, or death from kidney failure)in the intention-to-treat population of all responders. Safety was assessed in all patients who received at least one dose of their assigned study treatment. The study is registered with ClinicalTrials.gov, number NCT01858532. Findings: Between May 17, 2013, and July 13, 2017, 11 087 patients were screened; 5117 entered the enrichment period, and 4711 completed the enrichment period. Of these, 2648 patients were responders and were randomly assigned to the atrasentan group (n=1325)or placebo group (n=1323). Median follow-up was 2·2 years (IQR 1·4–2·9). 79 (6·0%)of 1325 patients in the atrasentan group and 105 (7·9%)of 1323 in the placebo group had a primary composite renal endpoint event (hazard ratio [HR]0·65 [95% CI 0·49–0·88]; p=0·0047). Fluid retention and anaemia adverse events, which have been previously attributed to endothelin receptor antagonists, were more frequent in the atrasentan group than in the placebo group. Hospital admission for heart failure occurred in 47 (3·5%)of 1325 patients in the atrasentan group and 34 (2·6%)of 1323 patients in the placebo group (HR 1·33 [95% CI 0·85–2·07]; p=0·208). 58 (4·4%)patients in the atrasentan group and 52 (3·9%)in the placebo group died (HR 1·09 [95% CI 0·75–1·59]; p=0·65). Interpretation: Atrasentan reduced the risk of renal events in patients with diabetes and chronic kidney disease who were selected to optimise efficacy and safety. These data support a potential role for selective endothelin receptor antagonists in protecting renal function in patients with type 2 diabetes at high risk of developing end-stage kidney disease. Funding: AbbVie
The Changing Landscape for Stroke\ua0Prevention in AF: Findings From the GLORIA-AF Registry Phase 2
- Author
- Abban Dzifa
- Abdul Nasser
- Abelson Mark
- Ackermann Alan
- Adams Fran
- Adams Luthando
- Adrag\ue3o Pedro
- Ageno Walter
- Aggarwal Rajesh
- Agosti Sergio
- Aguilar Linares Julio Alberto
- Aguilar Francisco
- Aguinaga Luis
- Ahmad Zia
- Ainsworth Paul
- Al Dallow Raed
- Al Ghalayini Kamal
- Al Ismail Saad
- Al Joundi Tammam
- Al Mahameed Soufian
- Al Obaidi Mohamed
- Al Zoebi Ayham
- Alasfar Abdelfatah
- Alawwa Abdul
- Alderson Lisa
- Alexopoulos Dimitrios
- Ali Abdullah
- Ali Malik
- Aliyar Pareed
- Almassi Hossein
- Almuti Khalid
- Alshehri Mohamed
- Altmann Ute
- Alves Alvaro Rabelo
- Amara Walid
- Amelot Mathieu
- Amjadi Nima
- Ammirati Fabrizio
- Andrawis Nabil
- Angela Koh Su Mei
- Angoulvant Denis
- Annoni Giorgio
- Ansalone Gerardo
- Antonescu Sorin Alexandru
- Ariani Mehrdad
- Arias Juan Carlos
- Armero S\ue9bastien
- Arora Chander
- Arora Rohit
- Ashcraft William
- Aslam M. Shakil
- Astesiano Alfredo
- Audouin Philippe
- Augenbraun Charles
- Aydin S.
- Azar Rabih
- Azim Abul
- Aziz Shahid
- B\uf8hmer Ellen
- Backes Luciano Marcelo
- Baig Mirza
- Bains Suchdeep
- Bakbak Asaad
- Baker Seth
- Bakhtiar Karim
- Bala Richard
- Banayan Jonathan
- Bandh Stellan
- Bando Shigenobu
- Banerjee Subhash
- Bank Alan
- Bar\uf3n Gonzalo
- Barbarash Olga
- Barr Craig
- Barrera Carlos
- Bartels Dorothee B.
- Barton John
- Baula Giovanni
- Bayeh Hamid
- Bazargani Nooshin
- Behrens Steffen
- Bell Alan
- Benezet Mazuecos Juan
- Benhalima Bouziane
- Berdagu\ue9 Philippe
- Berg van den B. J.
- Bergen van P. F. M. M.
- Berngard Edvard
- Bernstein Richard
- Berrospi Percy
- Berti Sergio
- Bertomeu Vicente
- Berz Andrea
- Bettencourt Paulo
- Betzu Robert
- Beyer Westendorf Jan
- Bhagwat Ravi
- Black Toby
- Blanco Ibaceta Jorge Hugo
- Bloom Stephen
- Blumberg Edwin
- Bo Mario
- Bockisch Valerie
- Bongiorni Maria Grazia
- Boriani Giuseppe
- Borret Mariano Ruiz
- Bosch Ralph
- Boswijk D. J.
- Bott Jochen
- Bottacchi Edo
- Brandes Axel
- Bratland Bj\uf8rn
- Brautigam Donald
- Breton Nicolas
- Briones Ignacio Rodriguez
- Brkljacic Diana Delic
- Brouwers P. J. A. M.
- Browne Kevin
- Bruguera Jordi
- Brunehaut Myriam
- Brunschwig Claude
- Bryan Yan Ping Yen
- Buathier Herv\ue9
- Buenostro Gabriel Contreras
- Buhl Aur\ue9lie
- Bullinga John
- Butcher Kenneth
- Cabrera Honorio Jose Walter
- Caccavo Alberto
- Cadinot Didier
- Cai Shanglang
- Caiedo Carolina Guevara
- Calin Podoleanu Cristian Gheorghe
- Calvi Valeria
- Camm John
- Candeias Rui
- Cao Phai G\ue9rald Phan
- Capo James
- Capucci Alessandro
- Cardoso Juliano Novaes
- Carlson Brian
- Carvalho Paula
- Cary Susanna
- Casanova Rene
- Casu Gavino
- Cattan Simon
- Cavallini Claudio
- Cayla Guillaume
- Cha Kwang Soo
- Cha Tae Joon
- Chaaban Said
- Chae Jei Keon
- Challappa Krishnan
- Chand Sunil
- Chandrashekar Harinath
- Chang Mark
- Charbel Paul
- Chartier Ludovic
- Chatterjee Kausik
- Cheema Aamir
- Chen Shih Ann
- Chevallereau Pierre
- Chiang Fu Tien
- Chiarella Francesco
- Chih Chan Lin
- Cho Yong Keun
- Choi Dong Ju
- Chouinard Guy
- Chow Hoi Fan
- Chreih Rami Mihail
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- Chumakova Galina
- Cieza Lara Tomas
- Ciobotaru Vlad
- Cislowski David
- Citerne Olivier
- Claus Matthias
- Clay Anthony
- Clifford Piers
- Cocina Emilio Gonzalez
- Cohen Andrew
- Cohen Serge
- Colivicchi Furio
- Collins R\uf3n\ue1n
- Compton Steve
- Connors Sean
- Conti Alberto
- Coodley Gregg
- Cooper Martin
- Corbett Lynn
- Corey Oran
- Coronel Juli\ue1n
- Corrigan John
- Cotrina Pereyra Rosa Ysabel
- Cottin Yves
- Coutu Benoit
- Cracan Aurel
- Crean Peter
- Crenshaw James
- Crijns H. J. G. M.
- Crump Charles
- Cucher Fred
- Cudmore David
- Cui Lianqun
- Culp John
- D'Souza Anthony
- Daniel Oh Chia Theng
- Danny Null
- Darius Harald
- Dary Patrick
- Dascotte Olivier
- Dauber Ira
- Davee Thomas
- Davies Ruth
- Davis Gershan
- Davy Jean Marc
- Dayer Mark
- De La Briolle Axel
- de Los Rios Ibarra Manuel Odin
- de Mora Manuel
- de Souza Olga Ferreira
- De Teresa Eduardo
- De Wolf Luc
- Decoulx Eric
- Deepak Sasalu
- Defaye Pascal
- Del Carpio Munoz Freddy
- Deluche Laurent
- Destrac Sylvain
- Deumite N. Joseph
- Di Legge Silvia
- Dibon Olivier
- Diemberger Igor
- Diener Hans Christoph
- Dillinger Jean
- Dion\uedsio Pedro
- Dotani Imran
- Dotcheva Elena
- Duarte Vera Yan Carlos
- Dubner Sergio J.
- Dubrey Simon
- Ducrocq Xavier
- Dupljakov Dmitry
- Duthinh Vuong
- Dutra Oscar Pereira
- Dutta Dipankar
- Duvilla Nathalie
- Dy Johnny
- Dziewas Rainer
- Eaton Charles
- Eaves William
- Ebinger Matthew
- Eck van J. W. M.
- Edwards Tim
- Egocheaga Isabel
- Ehrlich Clifford
- Eisenberg Steven
- El Hallak Abdel
- El Hamdani Mehiar
- El Jabali Adnan
- El Mahmoud Rami
- El Sayed Hassan
- El Shahawy Mahfouz
- Eldadah Zayd
- Elghelbazouri Fouad
- Elhag Omar
- Elias Darlene
- Ellery Adam
- Elsaesser Amelie
- Elvan A.
- Erickson Bernard
- Espaliat Eric
- Essandoh Louis
- Everington Tamara
- Evonich Rudolph
- Ezhov Andrey
- F\ue1cila Lorenzo
- Farsad Ramin
- Fayard Maxime
- Fedele Francesco
- Ferreira Daniel
- Ferrier Anna
- Finsen Alexandra
- First Brian
- Fisher Raymond
- Floyd John
- Folk Thomas
- Fonseca Catarina
- Fonseca Luisa
- Fonteles Ritt Luiz Eduardo
- Forman Steven
- Forsgren Magnus
- Foster Malcolm
- Foster Nathan
- Frais Michael
- Frandsen Brad
- Frapp\ue9 Thierry
- Freixa Ramon
- French William
- Freydlin Marina
- Frickel Siegfried
- Fruntelata Ana Gabriela
- Fujii Shigeru
- Fujino Yusuke
- Fukunaga Hiroshi
- Furukawa Yutaka
- G\uf6tte Andreas
- Gabelmann Matthias
- Gabris Michael
- Gadsb\uf8ll Niels
- Galin Pavel
- Galinier Michel
- Ganim Ricky
- Garcia Ronnie
- Gartenlaub Olivier
- Genz Conrad
- Georger Fr\ue9d\ue9ric
- Georges Jean Louis
- Georgeson Steven
- Ghanbasha Ali
- Giedrimas Evaldas
- Gierba Mariusz
- Gillespie Eve
- Giniger Alberto
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- Golitsyn Sergey
- Gomes Ferreira Luis Gustavo
- Gomez Lopez Efrain Alonso
- Gomez Mesa Juan Esteban
- Gonzalez Efrain
- Gorbunov Vladimir
- Gordon Brian
- Gorka Herv\ue9
- Gornick Charles
- Gorog Diana
- Goss Franz
- Goube Pascal
- Goudevenos Ioannis
- Goulden Dudley
- Gr\uf6nefeld Gerian
- Graham Brett
- Grande Angel
- Greco Cesare
- Green Martin
- Greer Gerald
- Gremmler Uwe
- Grena Paul
- Grinshstein Yuriy
- Grond Martin
- Gronda Edoardo
- Grondin Francois
- Groot de J. R.
- Guardigli Gabriele
- Guarnieri Thomas
- Guignier Alexandre
- Gulizia Michele
- Gumbley Michael
- Gupta Dhiraj
- Hack Terrence
- Haerer Winfried
- Hakas Joseph
- Hall Christian
- Halperin Jonathan L.
- Hampsey James
- Hananis Georgios
- Hanbali Basel
- Handel Franklin
- Hargrove Joe
- Hargroves David
- Harris Kenneth
- Hartley David
- Haruna Tetsuya
- Hata Yoshiki
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- Healey Jeff
- Hearne Steven
- Heggelund Geir
- Hemels M. E. W.
- Hemery Yann
- Henein Sam
- Henz Benhur
- Her Sung Ho
- Hermany Paul
- Hern\ue1ndez Norberto Matadamas
- Hernandes Mauro Esteves
- Higashino Yorihiko
- Hill Michael
- Hisadome Tetsuo
- Hishida Eiji
- Hitchcock James
- Hoffer Etienne
- Hoghton Matthew
- Holmes Clare
- Hong Suk Keun
- Houppe Nousse Marie Paule
- Howard Victor
- Hsu Li Fern
- Huang Chi Hung
- Huckins David
- Huehnergarth Kier
- Huisman Menno V
- Huizenga A.
- Huntley Richard
- Hussein Gamal
- Hwang Gyo Seung
- Igbokidi Oyidie
- Iglesias Ignacio
- Ikpoh Margaret
- Imberti Davide
- Ince H\ufcseyin
- Indolfi Ciro
- Ionova Tatiana
- Ip John
- Irles Didier
- Iseki Harukazu
- Ismail Younus
- Israel Noah
- Isserman Steven
- Iteld Bruce
- Ivanchura Galina
- Iyer Ramakrishnan
- Iyer Venkat
- Iza Villanueva Ruben Omar
- J\ue4ger Frank
- Jackson Voyzey Ewart
- Jaffrani Naseem
- Jain Manish
- James Martin
- Jamon Yann
- Jang Sung Won
- Jarmukli Nabil
- Jeanfreau Robert
- Jenkins Ronald
- Jiang Heng
- Jiang Nan
- Jiang Tiemin
- Jiang Xianyan
- Jimenez Javier
- Jobe Robert
- Joffe Ian
- Johansson Bengt
- Jones Nick
- Jos\ue9 Roberto Chuquiure Valenzuela Eduardo Juli\ue1n
- Jouve Bernard
- Juanatey Carlos Gonzalez
- Jundi Mayar
- Jung Byung Chun
- Jung Kyung Tae
- Jung Werner
- K\uf6hrmann Martin
- K\ufcmler Thomas
- K\ufcppers Achim
- Kabbani Samer
- Kabour Ameer
- Kafkala Chrystalenia
- Kajiwara Koji
- Kalan Marica Bracic
- Kalinina Larisa
- Kampus Priit
- Kanda Junji
- Kapadia Shaival
- Karim Amin
- Karolyi Laszlo
- Kashou Hisham
- Kastrup Andreas
- Katsivas Apostolos
- Kaufman Elizabeth
- Kawai Kazuya
- Kawajiri Kenji
- Kazmierski John
- Keeling Phil
- Kerfes Galal Ali
- Kerr Saraiva Jos\ue9 Francisco
- Kes Vanja Basic
- Ketova Galina
- Khaira Ajit
- Khalid Muhammad
- Khludeeva Elena
- Khripun Aleksey
- Kim Dae Kyeong
- Kim Doo Il
- Kim Jeong Su
- Kim Jin bae
- Kim June Soo
- Kim Ki Seok
- Kim Nam Ho
- Kim Young Hoon
- Kinova Elena
- Klein Alexander
- Kleinschnitz Christoph
- Kmetzo James
- Kneller G. Larsen
- Knezevic Aleksandar
- Koch Stanley
- Koenig Kai
- Koons Jay
- Korabathina Ravikiran
- Korennova Olga
- Koschutnik Martin
- Kosinski Edward
- Kovacic Dragan
- Kowalczyk Jacek
- Koziolova Natalya
- Kragten J. A.
- Krause Lars Udo
- Kreidieh Imad
- Krenning B. J.
- Krishnaswamy Kannappan
- Krysiak Waldemar
- Kuck Karl Heinz
- Kumar Somnath
- Kuniss Malte
- Kuo Jen Yuan
- Kurrelmeyer Karla
- Kwan Tak
- Kyo Eisho
- L\uf3pez Send\uf3n Jos\ue9
- Labovitz Arthur
- Lacroix Alain
- Lam Andy
- Lanas Zanetti Fernando Tomas
- Landau Charles
- Landini Giancarlo
- Lang Wilfried
- Larsen Torben Bjerregaard
- Laske Volker
- Lavandier Karine
- Law Nicki
- Lawrence Wong Ka Sing
- Lee Daniel
- Lee Moon Hyoung
- Leit\ue3o Ana
- Lejay Dominique
- Lelonek Malgorzata
- Lenarczyk Radoslaw
- Leprince Patrick
- Lequeux Benoit
- Leschke Matthias
- Ley Nicolas
- Li Weihua
- Li Xiaodong
- Li Yansheng
- Li Zhanquan
- Li Zicheng
- Liang Jianqiu
- Lieber Ira
- Lillestol Michael
- Limon Rodriguez Ramon Horacio
- Lin Hailong
- Lip Gregory
- Lip Gregory Y. H.
- Litchfield Jennifer
- Liu Feng
- Liu Wenhui
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- Liu Yalin
- Liu Zhitao
- Llamas Esperon Guillermo Antonio
- Llisterri Jose Luis
- Lo Eric
- Lo Ted
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- Lodde Bernhard Paul
- Loiselet Philippe
- Lorga Filho Adalberto Menezes
- Lori Ido
- Luo Ming
- Lupovitch Steven
- Lyrer Philippe
- M\ufcgge Andreas
- Ma Chang Sheng
- Ma Changsheng
- Ma Genshan
- Ma Hong
- Madariaga Irene
- Maeno Koji
- Magnin Dominique
- Mahmood Shahid
- Mahood Karen
- Maid Gustavo
- Mainigi Sumeet
- Makaritsis Konstantinos
- Maldonado Villalon Jos\ue9 Arturo
- Malhotra Rohit
- Malik Amir
- Mallecourt Catherine
- Mallik Rajiv
- Manning Rickey
- Manolis Athanasios
- Mantas Ioannis
- Manzur Jattin Fernando Gabriel
- Mar\uedn Francisco
- Marcionni Niccolo'
- Marin Javier Aguila
- Martinez Jorge
- Martinez Luis
- Maskova Petra
- Matskeplishvili Simon
- Matsuda Katsuhiro
- Mavri Alenka
- May Erik
- Mayer Nolan
- Mazon Pilar
- Mcclure John
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- Mcgarity William
- Mcguire Michael
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- Mehta Paresh
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- Mena Amparo
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- Michel Patrik
- Mikdadi Ghiath
- Mikhail Magdy
- Mikus Milan
- Milicic Davor
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- Miller Gary
- Milonas Christos
- Minescu Bogdan
- Mintale Iveta
- Miralles Aur\ue9lien
- Mirault Tristan
- Mistry Dinesh
- Mitchell George
- Miu Nicoleta Violeta
- Miyamoto Naomasa
- Moccetti Tiziano
- Mohammed Akber
- Molina de Salazar Dora Ines
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- Moodley Rajendra
- Moore Roger
- Morales Oscar Saenz
- Mori Kiyoo
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- Morka Jacek
- Moschos Nikitas
- Mota Gomes Marco Ant\uf4nio
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- Mousallem Nicolas
- Moya Angel
- Mulhearn Thomas
- Muller Jean Joseph
- Muresan Carmen Manuela
- Muse Derek
- Musial Wlodzimierz
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- Nakagawa Hidemitsu
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- Nakayama Toru
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- Nerheim Pamela
- Neuenschwander Fernando Carvalho
- Nica Violeta Cindea
- Nishida Kunihiro
- Nizov Alexey
- Nor Azlisham Mohd
- Novikova Tatiana
- Novo Salvatore
- Nowalany Kozielska Ewa
- Nsah Emmanuel
- Nunez Fragoso Juan Carlos
- Nyvad Ole
- O'Donnell Martin
- O'Donnell Philip
- O'Hara Gilles
- Oh Dong Jin
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- Oikonomou Kostas
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- Olivari Zoran
- Oliver Richard
- Olympios Christoforos
- Osborne John
- Osca Joaquin
- Osman Raed
- Osunkoya Abayomi
- Padanilam Benzy
- Panchenko Elizaveta
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- Paraschos Alexander
- Pardell Herbert
- Park Hyung Wook
- Park Jong Sung
- Parkash Ratika
- Parker Ian
- Parrens Eric
- Parris Robert
- Pascual Carlos Rodr\uedguez
- Passamonti Enrico
- Patel Jaydutt
- Patel Rajesh
- Pentz William H.
- Pereira Jardim Cesar Augusto
- Persic Viktor
- Perticone Francesco
- Peters Patrick
- Petkar Sanjiv
- Pezo Luis Felipe
- Pham David
- Phlaum Stephen
- Pineau Julien
- Pineda Velez Armando
- Pini Riccardo
- Pinter Arnold
- Pinto Fausto
- Pirelli Salvatore
- Pivac Nediljko
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- Pocanic Darko
- Polanczyk Carisi Anne
- Polasek Petr
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- Pollock Stewart
- Polo Jose
- Poock James
- Poppert Holger
- Porro Yamile
- Pose Antonio
- Poulain Fran\ue7ois
- Poulard Jean Ernst
- Pouzar Joe
- Povolny Petr
- Pozzer Domingo
- Pras Athanasios
- Prasad Neeraj
- Prevot S\ue9bastien
- Protasov Konstantin
- Prunier Laurent
- Puleo John
- Pye Maurice
- Qaddoura Fatma
- Quedillac Jean Michel
- Quintana Antonio Garcia
- Raev Dimitar
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- Ranjith Naresh
- Raposo Nuno
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- Raters Christa
- Rauch Kroehnert Ursula
- Rebane Thomas
- Regner Stefan
- Renzi Michael
- Reyes Rocha Miguel Agustin
- Reyes Humberto Rodriguez
- Reza Shabbir
- Ria Luigi
- Ribeiro Moreira Dalmo Antonio
- Richter Dimitrios
- Rickli Hans
- Rickner Kyle
- Rieker Werner
- Rigo Fausto
- Ripoll Tomas
- Roberts Douglas
- Roelke Marc
- Roman Mark
- Romeo Francesco
- Ronner E.
- Ronziere Thomas
- Rooyer F. A.
- Rosenbaum David
- Roth Sherryn
- Rothman Kenneth J.
- Rozkova Nadezda
- Rubacek Miroslav
- Rubalcava Frank
- Rubanenko Olesya
- Rubin Andrew
- Rybak Karin
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- Sakai Tetsuo
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- Salecker Ilsbe
- Salem Adrien
- Salfity Marwan
- Salguero Rafael
- Salvioni Alessandro
- Samson Mercedes
- Sanchez Gregorio
- Sandesara Chirag
- Santana Antonio Mart\uedn
- Santos Jos\ue9 Ferreira
- Saporito Wladmir Faustino
- Sasaoka Taishi
- Sattar Payman
- Savard Daniel
- Scala Pierre Jean
- Scemama Jacques
- Sch\uf6n Norbert
- Schaupp Thierry
- Schellinger Peter
- Scherr Carlos
- Schmitz Bettina
- Schmitz Karl Heinz
- Schmitz Lisa
- Schnitzler Robert
- Schnupp Steffen
- Schoeniger Peter
- Schuster Stefan
- Schwimmbeck Peter
- Seamark Clare
- Seebass Ruediger
- Seidl Karl Heinz
- Seidman Barry
- Sek Jaroslaw
- Sekaran Lakshmanan
- Seko Yoshinori
- Sepulveda Varela Pablo Andres
- Sevilla Bego\uf1a
- Shah Aman
- Shah Anil
- Shah Neerav
- Shah Vinay
- Shanes Jeffrey
- Sharareh Ali
- Sharma Vijay Kumar
- Shaw Louise
- Shimizu Yutaka
- Shimomura Hideki
- Shin Dong Gu
- Shin Eun Seok
- Shite Junya
- Shoukfeh Mohammad
- Shoultz Charles
- Silver Frank
- Sime Iveta
- Simmers T. A.
- Singal Dinesh
- Singh Narendra
- Siostrzonek Peter
- Sirajuddin Mohiburrahman
- Skeppholm Mika
- Smadja Didier
- Smith David
- Smith Richard
- Soda Hassan
- Sofley C. Wilson
- Sokal Adam
- Sotolongo Rodolfo
- Sparby Jon Arne
- Spinar Jindrich
- Sprigings David
- Spyropoulos Alex
- Stakos Dimitrios
- Steinberg Alon
- Steinwender Clemens
- Stergiou Georgios
- Stites H. William
- Stoikov Anastas
- Strasser Ruth
- Streb Witold
- Styliadis Ioannis
- Su Guohai
- Su Xi
- Suarez Rafael Martin
- Sudnik Wanda
- Sueyoshi Atsushi
- Sukles Kai
- Sun Li
- Suneja Randeep
- Svensson Peter
- Szavits Nossan Janko
- Taggeselle Jens
- Takagi Yuichiro
- Takhar Amrit
- Tallet Julio
- Tamm Angelika
- Tanaka Katsumi
- Tanaka Shozo
- Tang Aylmer
- Tang Sherman
- Tassinari Tiziana
- Tayama Shinji
- Tayebjee Muzahir
- Tebbe Ulrich
- Teixeira Jose
- Tesloianu Dan Nicolae
- Tessier Pascal
- Teutsch Christine
- The S. H. K.
- Thevenin J\ue9rome
- Thomas Harold
- Timsit Serge
- Topkis Robert
- Torosoff Mikhail
- Touze Emmanuel
- Traissac Thalie
- Trendafilova Elina
- Troyan Barry
- Tsai Wenchi Kevin
- Tse Hung Fat
- Tsutsui Hiroshi
- Tsutsui Takashi
- Tuininga Y. S.
- Turakhia Minang
- Turk Samir
- Turner Wayne
- Tveit Arnljot
- Twiddy Shannon
- Tytus Richard
- Ukrainski Gerald
- Valdovinos Chavez Salvador Bruno
- Van De Graaff Eric
- Vanacker Peter
- Vardas Panagiotis
- Vargas Michael
- Vassilikos Vassilios
- Vazquez Juan
- Venkataraman Asok
- Verdecchia Paolo
- Vester Ernst G\ufcnter
- Vial Hubert
- Vicenzo de Paola Angelo Amato
- Vinereanu Dragos
- Vlastaris Anthony
- Vogel Craig
- vom Dahl J\ufcrgen
- von Mering Matthias
- Vora Kishor
- Wakefield Paul
- Walia Jasjit
- Walter Thomas
- Wang Feng
- Wang Kuo Yang
- Wang Mingsheng
- Wang Ningfu
- Wang Xinhua
- Wang Zulu
- Watanabe Kouki
- Wei Jeanne
- Weimar Christian
- Weinrich Renate
- Wen Ming Shien
- Wheelan Kevin
- Wicke Jens
- Wiemer Marcus
- Wild Beate
- Wilke Andreas
- Willems Stephan
- Williams David
- Williams Marcus
- Winkler Andreas
- Wirtz Jost Henner
- Witzenbichler Bernhard
- Wong Brian
- Wong Danny H. K.
- Wozakowska Kaplon Beata
- Wu Shulin
- Wu Zhaohui
- Wyatt Nell
- Xu Xiangdong
- Xu Yong
- Yamada Akira
- Yamamoto Kazuya
- Yamanoue Hiroki
- Yamashita Takeshi
- Yang Tianlun
- Yang Yanmin
- Yao Jing
- Yarlagadda Chakri
- Yeh Kuo Ho
- Yotov Yoto
- Yvorra Serge
- Zahn Ralf
- Zamorano Jos\ue9
- Zanini Roberto
- Zarich Stuart
- Zebrack James
- Zenin Sergei
- Zeuthen Elisabeth Louise
- Zhang Dadong
- Zhang Donghui
- Zhang Huanyi
- Zhang Quansan
- Zhang Xingwei
- Zhao Shuiping
- Zhao Xinwen
- Zheng Qiangsun
- Zheng Yang
- Zhou Jian
- Zhou Jing
- Ziekenhuis Antonius
- Zimmermann Rainer
- Zimmermann Sergio Luiz
- Zint Kristina
- Zuhairy Hamed M.
- Zukerman L. Steven
- Zwaan van der C.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2017
- Field of study
Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non\u2013vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase 1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients\u2019 baseline characteristics. Atrial fibrillation disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age 6575 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score 652; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc = 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N = 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in Asia and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
- Avila Aaron
- Avis Terry
- Ayele Mulu
- Babayan Primo
- Babbage Anne
- Babbage Sarah
- Bach Phil
- Bachatsang Pasang
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- Kruchowski Scott S.
- Kube Michael
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- Lowry Stephen
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- Un Chun
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- Upson Darren
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- Wickremasinghe Manosha I.
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- Wilkinson Jane
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- Williamson Helen
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- Wong Gane K-S
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- Wooden Steven H.
- Woodeson Sharon
- Woodfine Kathryn
- Woodmansey Rebecca
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- Worley Kim Carlyle
- Woyke Tanja
- Wray Matthew
- Wray Paul
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- Wright Debbie
- Wright Kathrine
- Wright Kristin
- Wright Rita A.
- Wu Chungen
- Wu Dongying
- Wu Jiaqian
- Wu Jung-Rung
- Wu Kevin
- Wu Qingfa
- Wu Qingfa
- Wu Ruiming
- Wu Xiao
- Wu Xiaojing
- Wu Zaining
- Wyatt Julia
- Wycoff-Montenegro Melissa
- Wylie Kris
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- Xi Yan
- Xi Yingying
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- Xu Alex
- Xu Jing
- Xu Jing
- Xu Ruqin
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- Xu Xinlai
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- Xu Yuning
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- Xu Zuyuan
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- Xue Rui
- Yada Tetsushi
- Yadav Shailendra
- Yakub Syed
- Yamamoto Lynn
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- Yamamoto Yuko
- Yamashita Yasue
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- Yang Hao
- Yang Huanming
- Yang Huanming
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- Yang Shudong
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- Yang Xiaonan
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- Yao Zhijian
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- Ye Chen
- Yeager Shane
- Yeh Mimi
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- Yeshitela Rahel Retta
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- Zhang Guohua
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- Zhang Haiqing
- Zhang Haiqing
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- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
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- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
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- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
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- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials
- Author
- Aaronson Keith
- Abadier Rafik
- Abbasi Siddique A.
- Abdullah Shuaib
- Abelson Mark
- Abhayaratna Walter
- Ablasser Klemens
- Aboyans Victor
- Abo‐Auda Wael
- Abuannadi Mohammad
- Adams Kirkwood
- Adams Kirkwood F.
- Adhya Shaumik
- Adler Alexander
- Aggarwala Gaurav
- Agostoni Piergiuseppe
- Ahmad Saad
- Aiub Jorge Roberto
- Al Mohammad Abdallah
- Alharethi Rami
- Alieksieieva Liudmyla
- Almeida Filipa
- Almousalli Omar
- Amano Tetsuya
- Amanullah Aman
- Ambardekar Amrut
- Amerena John
- Anand Inder
- Anderson William
- Ando Kenji
- Andreka Peter
- Antalik Lubomir
- Aradi Daniel
- Araiza Raul Reyes
- Arbolishvili Georgy
- Ariani Mehrdad
- Arias‐Mendoza Alexandra
- Arora Raveen
- Arroyo Julian Alonso Coronel
- Artis Andre
- Asakura Masanori
- Asano Hiroshi
- Ashcom Thomas
- Aslam Shamaila
- Asubiaro Joshua
- Atherton John
- Avaca Horacio Alberto
- Babapulle Mohan
- Bacal Fernando
- Badak Ozer
- Badariene Jolita
- Badat Aysha
- Baker Mathue
- Balsam Pawel
- Banerji Sourin
- Barbarash Olga
- Barbetseas Ioannis
- Barr Craig
- Barros e Silva Pedro Gabriel Melo
- Barua Rajat
- Bauerlein Eugene Joseph
- Baweja Paramdeep
- Bednarkiewicz Zbigniew
- Beelen Driek
- Begg Alistair
- Bekar Lutfu
- Belenkiy Dmitriy
- Belohlavek Jan
- Beltrame John
- Berdague Philippe
- Berglund Stefan
- Berk Martin
- Berkowski Piotr
- Berra Fernando Colombo
- Bertolet Barry
- Besada Diego Alejandro
- Beug Daniel
- Bezzegh Katalin
- Bhagwat Ravi
- Bhargava Rakesh
- Biering‐Sørensen Tor
- Bilato Claudio
- Blicharski Tomasz
- Boccalandro Fernando
- Boehm Michael
- Boehmer John
- Bogaev Roberta
- Bolshakova Olga
- Boman Kurt
- Bonderman Diana
- Bonet Luis Almenar
- Bonfanti Alberto Cadena
- Bordonava Anselmo Paulino
- Bostick Brian
- Boswijk Dirk
- Bourgeois Ronald
- Bourhaial Hakima
- Bouza Manuel
- Braga Joao Carlos
- Brasca Daniela Garcia
- Brinkley Douglas
- Brito Dulce
- Brunetti Natale Daniele
- Bruno Marco Raul Litvak
- Bu Peili
- Burgess Lesley
- Busak Ladislav
- Buynak Robert
- Buysschaert Ian
- Bykov Alexander
- Böhm Michael
- Caccavo Alberto
- Canesin Manoel
- Cardona Jose
- Cardoso Juliano
- Carluccio Erberto
- Carrasco Jose Alfredo Pagola
- Carson Peter
- Castillo Armando Garcia
- Cavallini Claudio
- Cavusoglu Yuksel
- Cech Vladimir
- Celik Ahmet
- Celutkiene Jelena
- Cepelak Michal
- Cerci Rodrigo Julio
- Chandra Lokesh
- Chandrasekaran Badrinathan
- Chang David
- Chaves Renato
- Chehayeb Raja
- Cheirif Jorge
- Chen Guoqin
- Chen Jiyan
- Chmielak Zbigniew
- Chouchane Iman
- Chung Eugene
- Cid Maria Cristina Schnettler
- Civitello Andrew
- Clark Andrew
- Cleland John G.F.
- Clifford Piers
- Coletti Andrew
- Collins John
- Colque Roberto
- Constance Christian
- Contreras Johanna
- Corbalan Ramon
- Corbalan Ramon
- Correa Luis Eduardo Echeverria
- Corredor Miguel Alfredo Moncada
- Cosansu Kahraman
- Costa‐Vitali Atilio
- Cotarlan Vladimir
- Coufal Zdenek
- Cox Jeremy
- Crespo‐Leiro Maria G.
- Cruz Kimberly
- Cubero Javier Segovia
- Cui Hanbin
- Cymerman Krzysztof
- Dahlström Ulf
- Damy Thibaud
- Dauber Ira
- De Geeter Guillaume
- De los Rios Ibarra Manuel Odin
- De Pasquale Carmine
- Decoulx Eric
- Demir Mesut
- Desai Pratik
- Diaz Rafael
- Diaz Rafael
- Diaz Victor Alfonso Jimenez
- Dib Nabil
- Diez Mirta
- Dimov Bojidar
- Doblas Juan Jose Gomez
- Doi Masayuki
- Domae Hiroshi
- Donal Erwan
- Dong Yugang
- Donnelly Patrick
- Dorobantu Maria
- Dovgolis Svetlana
- Doyle Timothy
- Drexel Heinz
- Dronov Dmitry
- Droogne Walter
- Drozdz Jaroslaw
- Duarte Tatiana
- Duengen Hans‐Dirk
- Dujardin Karl
- Dupont Matthias
- Duran Ruben Omar Garcia
- Duzenli Mehmet
- Dzupina Andrej
- Eaton Charles
- Ebato Mio
- Ebelt Henning
- Eberly Arthur
- Ebner Christian
- Echeverria Correa Luis E.
- Elliott James
- Elmahi Einas
- Elvan Arif
- Esperon Guillermo Antonio Llamas
- Ezekowitz Justin
- Ezhov Marat
- Fang James
- Fang James C.
- Farris Neil
- Feitell Scott
- Felker G. Michael
- Fernandez Alberto
- Fernando Ronald
- Ferraz Almir
- Figal Domingo Andres Pascual
- Filho Otavio Coelho
- Filho Pedro Pimentel
- Filippatos Gerasimos
- Fisher Daniel
- Florea Viorel
- Flores Ana Maria De Leon
- Floresta Agata Marina
- Fonseca Candida
- Fonseca Cândida
- Forman Steven
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- Fortes Jose Augusto Ribas
- Fourie Nyda
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- Frank Theodore
- Frankenstein Lutz
- Freire Ramon Bover
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- Friedman Keith
- Frigerio Maria
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- Fu Xin
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- Fujiwara Wakaya
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- Gabriel George
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- Galinier Michel
- Ganeshram Vedampattu
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- Garrido Marcelo Alejandro
- Gass Alan
- Gaudet Daniel
- Geltman Edward
- Gemignani Anthony
- Genth‐Zotz Sabine
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- Glover Jason
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- Gola Zbigniew
- Goloshchekin Boris
- Goncalvesova Eva
- Goncalvesova Eva
- Goncharov Ivan
- Gonsorcik Jozef
- Gonzalez Ricardo Garcia
- Gonzalez Salvador Leon
- Gordon Brian
- Gorodeski Eiran
- Gottlieb Stephen
- Goudev Assen
- Goudev Assen R.
- Gray Wayne
- Grazette Luanda
- Greco Oswaldo
- Grewal Gurinder
- Groote Pascal De
- Gueffet Jean‐Pierre
- Guerrero Rodolfo Andres Ahuad
- Gupta Dinesh
- Gupta Milan
- Guray Umit
- Haddad Tariq
- Haehling Stephan
- Hajko Erik
- Hal John
- Halpern Stephen
- Hametz Craig
- Hamilton Andrew
- Han Qinghua
- Han Yajun
- Handel Franklin
- Hara Hisao
- Harris John
- Hart Hamish
- Hart Terence
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- Hasni Syed
- Hata Yoshiki
- Hattler Brack
- Hearne Steven
- Hedgepeth Chester
- Heilman Karl
- Heitner John
- Henderson David
- Herczeg Bela
- Hermans Walter
- Herzog William
- Hidaka Takayuki
- Hidalgo Mario Yanez
- Higashino Yorihiko
- Hiroi Shitoshi
- Hominal Miguel Angel
- Horacek Thomas
- Houra Marek
- Houston Brian
- Howlett Jonathan G.
- Huang He
- Huber Kurt
- Huelsmann Martin
- Hullin Roger
- Hunter Vernon
- Huynh Thao
- Ibañez Julio
- Ibrahim Hassan
- Indolfi Ciro
- Inomata Takayuki
- Iseki Harukazu
- Ishikawa Masahiro
- Isnard Richard
- Isshiki Takaaki
- Itchhaporia Dipti
- Ito Hiroshi
- Jackson Bruce
- Jacob Binu
- Jadbabaie Farid
- Jaeger Cristiano Pederneiras
- Jaffrani Naseem
- Jalaf Margarita Gertrudis Vejar
- Janik Matthew
- Jankowski Piotr
- Janmohamed Munir
- Jarasuniene Dalia
- Jattin Fernando Manzur
- Javier Julian
- Jeppesen Jorgen
- Jerabek Ondrej
- Jimenez Juan Francisco Delgado
- Jofre Christian Paolo Pincetti
- Jondeau Guillaume
- Jones Alonzo
- Joseph Susan
- Juanatey Jose Ramon Gonzalez
- Judkins Christopher
- Kadel Christoph
- Kadokami Toshiaki
- Kafara Mariusz
- Kai Hisashi
- Kaiser‐Nielsen Peter
- Kajinami Kouji
- Kalarus Zbigniew
- Kalecinska‐Krystkiewicz Ewa
- Kalra Paul
- Kaluski Edo
- Kanda Junji
- Kania Grzegorz
- Kao John
- Karavidas Apostolos
- Karim Amin
- Karlstrom Patric
- Karpenko Oleksandr
- Karvounis Haralambos
- Kasai Toshio
- Kassiotis Christos
- Katz Richard
- Kawakami Hideo
- Kawamitsu Katsunori
- Kawasaki Tomohiro
- Kazemi Navid
- Kazinczy Rita
- Kearney Leighton
- Keeling Philip
- Kellnerova Ivana
- Khalife Wissam
- Kida Keisuke
- Killat Holger
- Kindel Carlos Conejeros
- King Anthony
- Kirma Cevat
- Kitaoka Hiroaki
- Klimsa Zdenek
- Klug Eric
- Kobalava Zhanna
- Kochiadakis George
- Koga Tokushi
- Koike Akihiro
- Koizumi Tomomi
- Koldas Zehra Lale
- Koleckar Pavel
- Komiyama Nobuyuki
- Kondo Nicholas
- Konieczynska Malgorzata
- Kono Alan
- Koo Charles
- Kopaczewski Jerzy
- Korczyk Dariusz
- Koren Michael
- Korzh Oleksii
- Kosmacheva Elena
- Kostenko Viktor
- Kotelnikov Mikhail
- Kowalski Robert
- Kracz Igor
- Krantz Mori
- Krishnamoorthy Arun
- Krupicka Jiri
- Kryza Radim
- Kubota Toru
- Kulibaba Elena
- Kulynych Oleksii
- Kurtz Christopher E.
- Kwan Michael
- Lader Ellis
- Lakatos Ferenc
- Lakshminarayanan Batlagundu
- Lancellotti Patrizio
- Lanfear David E.
- Lang Chim
- Lang Christopher
- Laperche Thierry
- Laszlo Zoltan
- Leaes Paulo Ernesto
- Lefebvre Jean‐Marie
- Legg Jason C.
- Leiro Maria Generosa Crespo
- Lelonek Malgorzata
- Lenartowska Lucyna
- Lenner Egon
- Leon Jose Luis Arenas
- Leonardi Sergio
- Lepor Norman
- LeWinter Martin
- Lewis Neil
- Li Dongye
- Li Jianjun
- Li Tianfa
- Li Weimin
- Li Yinjun
- Li Zhangquan
- Li Zhaoping
- Lighezan Daniel
- Lindholm Carl‐Johan
- Linssen Gerardus
- Liu Feng
- Llamas Edmundo Alfredo Bayram
- Llerena Sara
- Lohr Nicole
- Londono Juan
- Lopez Gabriel Arturo Ramos
- Lopez Luis Horacio Atehortua
- Lopez Rodrigo Botero
- Lovell Charles
- Ludman Andrew
- Luengas Carlos Alberto
- Lukacova Jana
- Lukyanov Yury
- Lund Marianne
- Lund Mayanna
- Lupkovics Geza
- Lupovitch Steven
- Luquez Hugo
- Lymar Yurii
- Lynch Mary
- Ma Shumei
- Macarie Cezar‐Eugen
- Macdonald Peter
- Macdonald Peter
- Machado Gustavo Francisco Mendez
- Machova Vilma
- Macias Leonardo
- Mackinnon Ignacio
- Maejima Yasuhiro
- Magro Michael
- Mahemuti Ailiman
- Mahmood Shahid
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- Mamdani Shafiq
- Mancini Donna
- Manenti Euler Roberto Fernandes
- Manita Mamoru
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- Mareev Vyacheslav
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- Ramires Felix J. A.
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- Ranadive Nandkishore
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- Rossini Roberta
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- Skrobakova Janka
- Slapikas Rimvydas
- Sliwa Karen
- Sluis Aize
- Smart Frank
- Smik Rudolf
- Smilde Tom
- Sobkowicz Bozena
- Sochor Karel
- Sokos George
- Solomon Scott D.
- Solovev Oleg
- Souza Weimar Kunz Barroso
- Spacek Rudolf
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- Spinar Jindrich
- Spinarova Lenka
- Spiridon Marilena Renata
- Spyra Janusz
- Stahl Llyod
- Stamate Sorin
- Stanciulescu Gabriela
- Stanislavchuk Mykola
- Stankiewicz Anna
- Starling Randall
- Stepek David
- Stets Roman
- Stevlik Jan
- Stewart Robert
- Stoddard Marcus
- Straburzynska‐Migaj Ewa
- Strader J Russell
- Styliadis Ioannis
- Störk Stefan
- Sugino Hiroshi
- Sulemanjee Nasir
- Sun Yuemin
- Sussex Bruce
- Suter Thomas
- Suter Thomas M.
- Suzuki Masahiro
- Sverdlov Aaron
- Sweitzer Nancy
- Szabo Barna
- Szakal Imre
- Szasz Gyula
- Szczasny Marcin
- Szto Gregory
- Taggeselle Jens
- Tahirkheli Naeem
- Takagi Atsutoshi
- Takahashi Natsuki
- Takaishi Hiroshi
- Takama Noriaki
- Takata Theodore
- Takeishi Yasuchika
- Takenaka Takashi
- Tallet Julio
- Tanabe Jun
- Tanaka Takahiro
- Tang Huifang
- Tarasov Nikolay
- Tartiere Jean‐Michel
- Tatebe Shunsuke
- Taylor Justin
- Teerlink John R.
- Terasaki Toshiro
- Terasawa Akihiro
- Tereschenko Sergey
- Timofeev Alexander
- Tisheva‐ Gospodinova Snezhanka
- Tocchetti Carlo Gabriele
- Todorov Georgi
- Tognon Alexandre
- Tomcsanyi Janos
- Tomcsanyi Janos
- Toth Kalman
- Treasure Charles
- Trebacz Jaroslaw
- Trevelyan Jasper
- Triana Miguel Urina
- Trichon Benjamin
- Trochu Jean Noel
- Tsabedze Nqoba
- Tsao Lana
- Tseluyko Vira
- Tsioufis Konstantinos
- Tsujimoto Mitsuru
- Tuncer Mustafa
- Turgut Okan Onur
- Tyl Petr
- Tzekova Maria
- Tziakas Dimitrios
- Ueda Yasunori
- Ueno Hideki
- Uhliar Rudolf
- Ujino Keiji
- Uretsky Barry
- Usui Makoto
- Utsu Noriaki
- Vaccari Christopher
- Vakaliuk Igor
- Van Eck Jacob
- Van Kesteren Henricus
- Van Zyl Louis
- Vandekerckhove Hans
- Vandekerckhove Hans
- Vanhecke Thomas
- Varin Claire
- Vasallo Javier
- Vasilev Ivaylo
- Vasilyeva Larysa
- Vaz Garth
- Vazquez Eduardo Salcido
- Vega Mario
- Velikov Chavdar
- Venegas Manuel Eduardo Rodriguez
- Videbaek Lars
- Vidotti Maria Helena
- Vijay Nampalli
- Vilamajo Oscar Alberto Gomez
- Vilchez Francisco Gonzalez
- Villani Giovanni Quinto
- Villoch Mario
- Villota Julio Eduardo Nuñez
- Vinanska Daniela
- Vincenzi Antonella
- Vinereanu Dragos
- Vinereanu Dragos
- Vishnevsky Alexander
- Voevoda Mikhail
- Vogel Daniel
- Voicu Olga‐Cristina
- Volterrani Maurizio
- Voors Adriaan
- Voors Adriaan A.
- Voronkov Leonid
- Vraa Soren
- Wada Atsuyuki
- Wahid Faisal
- Wal Ruud
- Wang Yi
- Wang Zhifang
- Watanabe Naoki
- Wei Yu
- Weir Robin
- Westenfeld Ralf
- Wheeler Matthew
- Whellan David
- Wiggers Henrik
- Wilkett Matt
- Willems Frank
- Williams Celeste
- Wlodarczyk Aleksander
- Wodlin Peter
- Wong Kenneth
- Wozakowska‐Kaplon Beata
- Wu Weiheng
- Yagensky Andriy
- Yamamoto Mitsutaka
- Yan Jing
- Yang Ping
- Yang Xuming
- Yang Zhenyu
- Yeoman Gary
- Yigit Zerrin
- Yilmaz Mehmet B.
- Yoshida Takeshi
- Yoshikawa Masaki
- Yousuf Kabir
- Yuan Zuyi
- Yuge Masaru
- Zabowka Maciej
- Zaca Valerio
- Zaidman Cesar
- Zanetti Fernando Tomas Lanas
- Zannad Faiez
- Zapata Gerardo
- Zdrenghea Dumitru
- Zeman Kamil
- Zeymer Uwe
- Zhang Jinguo
- Zhang Lily
- Zhang Shouyan
- Zhang Xuelian
- Zhang Yuhui
- Zhang Yuqing
- Zheng Yang
- Zheng Zhe
- Zhou Changyong
- Zieroth Shelley
- Zilahi Zsolt
- Zimmet Hendrik
- Zolty Ronald
- Zrazhevskiy Konstantin
- Zwaan Coenraad
- Publication venue
- 'Wiley'
- Publication date
- 01/11/2020
- Field of study
Aims:
The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTIC‐HF) trial. Here we describe the baseline characteristics of participants in GALACTIC‐HF and how these compare with other contemporary trials.
Methods and Results:
Adults with established HFrEF, New York Heart Association functional class (NYHA) ≥ II, EF ≤35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokinetic‐guided dosing: 25, 37.5 or 50 mg bid). 8256 patients [male (79%), non‐white (22%), mean age 65 years] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NT‐proBNP 1971 pg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTIC‐HF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressure < 100 mmHg (n = 1127), estimated glomerular filtration rate < 30 mL/min/1.73 m2 (n = 528), and treated with sacubitril‐valsartan at baseline (n = 1594).
Conclusions:
GALACTIC‐HF enrolled a well‐treated, high‐risk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation
Cardiac myosin activation with omecamtiv mecarbil in systolic heart failure
- Author
- A Alan Chu
- A Shekhar Pandey
- Aaron Sverdlov
- Abbasi S. A.
- Abdallah Al Mohammad
- Abdul Al-Hesayen
- Adams K. F.
- Adnan Malik
- Adriaan Voors
- Adrian Shandling
- Agata Marina Floresta
- Ahmet Celik
- Ailiman Mahemuti
- Aize van der Sluis
- Akihiro Koike
- Akihiro Nakamura
- Akihiro Terasawa
- Alan Gass
- Alan Kono
- Alan Meholick
- Alberto Caccavo
- Alberto Cadena Bonfanti
- Alberto Esteban Bazzoni Ruiz
- Alberto Fernandez
- Alberto Margonato
- Aldo Prado
- Alejandro Recio Mayoral
- Aleksander Wlodarczyk
- Aleksandra Manolova
- Alessandro Fucili
- Alex Mauricio Villablanca Sepulveda
- Alexander Adler
- Alexander Bykov
- Alexander Parkhomenko
- Alexander Sherenkov
- Alexander Timofeev
- Alexander Vishnevsky
- Alexandr Schee
- Alexandra Arias Mendoza
- Alexandre Tognon
- Alexey Repin
- Alicia Contreras Rodriguez
- Alina Giuca
- Alisdair Ryding
- Alistair Begg
- Almir Ferraz
- Alonzo Jones
- Amal Muthumala
- Aman Amanullah
- Amarinder Bindra
- Amin Karim
- Amin Yehya
- Amit Shah
- Amrut Ambardekar
- Ana Maria De Leon Flores
- Anand I.
- Anays Santana Izquierdo
- Andras Papp
- Andre Artis
- Andrea Mortara
- Andrej Dzupina
- Andres Iñiguez Romo
- Andrew Boyle
- Andrew Civitello
- Andrew Clark
- Andrew Coletti
- Andrew Hamilton
- Andrew Ludman
- Andrew Sauer
- Andrew Sindone
- Andriy Yagensky
- Andrzej Rynkiewicz
- Aniko Papp
- Anil Shah
- Anna Paszczuk
- Anna Stankiewicz
- Anselmo Paulino Bordonava
- Anthony Gemignani
- Anthony King
- Antonella Vincenzi
- Antonio Juan Castro Fernandez
- Antonio Lara Padron
- Apostolos Karavidas
- Arias-Mendoza A.
- Arif Elvan
- Arman Postadzhiyan
- Armando Garcia Castillo
- Arnold Seto
- Arthur Eberly 3rd
- Arun Krishnamoorthy
- Arunima Misra
- Assad Mouhaffel
- Assen Goudev
- Athanasios Manolis
- Atilio Costa-Vitali
- Atsushi Hirayama
- Atsutoshi Takagi
- Atsuyuki Wada
- Attila Mohacsi
- Aurelio Ortiz
- Aysha Badat
- Badrinathan Chandrasekaran
- Balgit Chhokar
- Barbara Pisani
- Barna Szabo
- Barry Bertolet
- Barry H Greenberg
- Barry Uretsky
- Batlagundu Lakshminarayanan
- Beat Knusel
- Beata Wozakowska-Kaplon
- Beatriz Diaz Molina
- Bela Herczeg
- Bela Merkely
- Benjamin Trichon
- Bhola Rama
- Biering-Sorensen T.
- Binoy Skaria
- Binu Jacob
- Bohm M.
- Bojidar Dimov
- Bonderman D.
- Boris Goloshchekin
- Bozena Sobkowicz
- Brack Hattler
- Bradley Weinberg
- Brenda Lemus
- Brenda Peart
- Brian Bostick
- Brian Claggett
- Brian Gordon
- Brian Houston
- Bruce Jackson
- Bruce Sussex
- Bruno Paolino
- Candida Fonseca
- Carl-Johan Lindholm
- Carlo Gabriele Tocchetti
- Carlos Alberto Luengas
- Carlos Arrieta Garcia
- Carlos Conejeros Kindel
- Carlos Poy
- Carmine De Pasquale
- Carol Davila
- Carsten Schmalfuss
- Celeste Williams
- Cesar Zaidman
- Cevat Kirma
- CezarEugen Macarie
- Changyong Zhou
- Charles Eaton
- Charles Koo
- Charles Lovell
- Charles Treasure
- Chavdar Velikov
- Chester Hedgepeth
- Chiara Melloni
- Chim Lang
- Christian Constance
- Christian Ebner
- Christian Mueller
- Christian Paolo Pincetti Jofre
- Christoph Kadel
- Christopher E Kurtz
- Christopher Judkins
- Christopher Lang
- Christopher Pickett
- Christopher Rowan
- Christopher Vaccari
- Christos Kassiotis
- Ciro Indolfi
- Claire Varin
- Clara Ines Saldarriaga Giraldo
- Claudia Raineri
- Claudio Bilato
- Claudio Cavallini
- Claudio Rodolfo Majul
- Cleland J. G. F.
- Coenraad van der Zwaan
- Constantin Militaru
- Corbalan R.
- Craig Barr
- Craig Hametz
- Crespo-Leiro M. G.
- Cristian Gheorghe Podoleanu
- Cristiano Pederneiras Jaeger
- Cristina Danila
- Csaba Salamon
- Dahlstrom U.
- Dalia Jarasuniene
- Dallas Price
- Dalton McLean
- Daniel Aradi
- Daniel Beug
- Daniel Fisher
- Daniel Gaudet
- Daniel Lenihan
- Daniel Lighezan
- Daniel Pauly
- Daniel Savard
- Daniel Vogel
- Daniela Garcia Brasca
- Daniela Pini
- Daniela Vinanska
- Dariusz Korczyk
- David Chang
- David F Kong
- David Henderson
- David Lanfear
- David Murray
- David Rawitscher
- David Schultz
- David Stepek
- David Whellan
- Debashis Roy
- Deddo Moertl
- Denis-Carl Phaneuf
- Dennis Rupka
- Deovrat Singh
- Devesh Patel
- Diana Bonderman
- Diaz R.
- Diego Alejandro Besada
- Diego Felipe Martinez
- Dimitrios Tziakas
- Dinesh Gupta
- Dipti Itchhaporia
- Dirk Boswijk
- Dirk Lok
- Dirk Schellings
- Dmitriy Belenkiy
- Dmitry Dronov
- Dmytro Reshotko
- Domenico Bonaduce
- Domingo Andres Pascual Figal
- Dongye Li
- Donna Mancini
- Dora Ines Molina de Salazar
- Douglas Brinkley
- Douglas Martel
- Douglas Sawyer
- Dragos Vinereanu
- Driek Beelen
- Dulce Brito
- Dumitru Zdrenghea
- Echeverria L. E.
- Edmundo Alfredo Bayram Llamas
- Edo Kaluski
- Eduardo Perna
- Eduardo Salcido Vazquez
- Edward Geltman
- Edward Portnay
- Egon Lenner
- Eileen O'Meara
- Einas Elmahi
- Eiran Gorodeski
- Elena Cowan
- Elena Kosmacheva
- Elena Kulibaba
- Elena Shutemova
- Ellis Lader
- Elvin Kedhi
- Erberto Carluccio
- Eric Decoulx
- Eric Klug
- Erik Hajko
- Ersel Onrat
- Ertugrul Okuyan
- Erwan Donal
- Eugene Chung
- Eugene Joseph Bauerlein
- Euler Roberto Fernandes Manenti
- Eva Goncalvesova
- Eva Peterfai
- Ewa Kalecinska-Krystkiewicz
- Ewa Straburzynska-Migaj
- Fabiana Rollini
- Fabio Silveira
- Fady I Malik
- Faiez Zannad
- Faisal Wahid
- Fang J. C.
- Farid Jadbabaie
- Felice Achilli
- Felix Ramires
- Feng Liu
- Ferenc Lakatos
- Fernando Bacal
- Fernando Boccalandro
- Fernando Colombo Berra
- Fernando Manzur Jattin
- Fernando Soto Loureiro
- Fernando Tomas Lanas Zanetti
- Filipa Almeida
- Filippatos G.
- Flavio Brito
- Flavio Eduardo Giorgeto
- Florence Rothenberg
- Florin Mitu
- Fonseca C.
- Fragkiskos Parthenakis
- Francesco Franchi
- Francisco Gonzalez Vilchez
- Francois Roubille
- Frank McGrew
- Frank Smart
- Frank Willems
- Franklin Handel
- François Picard
- Freny Mody
- Friedrich Fruhwald
- Fumi Yamamoto
- G Michael Felker
- Gabriel Arturo Ramos Lopez
- Gabriela Stanciulescu
- Gabriele Jakl-Kotauschek
- Gaetano Maria De Ferrari
- Garth Vaz
- Gary Yeoman
- Gaurav Aggarwala
- Georg Noll
- George Gabriel
- George Kochiadakis
- George Marzouka
- George Sokos
- Georgi Todorov
- Georgiy Dzyak
- Georgy Arbolishvili
- Gerardo Zapata
- Gerardus Linssen
- Gerasimos Filippatos
- Gerhard Poelzl
- Geza Lupkovics
- Giancarlo Piovaccari
- Gianfranco Sinagra
- Gianpiero Perna
- Gilmar Reis
- Gintare Sakalyte
- Giovanni Geronilla
- Giovanni Quinto Villani
- Giuseppe Ambrosio
- Giuseppe Musumeci
- Glenn Hamroff
- Goncalvesova E.
- Gordon Moe
- Gordon Reeves
- Goudev A. R.
- Gregorio Sanchez Vallejo
- Gregory Sampognaro
- Gregory Szto
- Gregory Thomas
- Grigorios Giamouzis
- Grzegorz Kania
- Grzegorz Skonieczny
- Guillaume De Geeter
- Guillaume Jondeau
- Guillermo Antonio Llamas Esperon
- Guoqin Chen
- Gurinder Grewal
- Gurusher Panjrath
- Gustavo Francisco Mendez Machado
- Guy Proulx
- Gyula Szasz
- Hakima Bourhaial
- Hal Skopicki
- Hamish Hart
- Hanbin Cui
- Hans Vandekerckhove
- Hans-Dirk Duengen
- Haralambos Karvounis
- Harinder Gogia
- Harukazu Iseki
- Hassan Ibrahim
- He Huang
- Heinz Drexel
- Hendrik Zimmet
- Henning Ebelt
- Henricus Van Kesteren
- Henrik Wiggers
- Henry Dargie
- Henry Ooi
- Hernan Emilio Francisco Polo Friz
- Hideki Ueno
- Hideo Izawa
- Hideo Kawakami
- Hideyuki Tsuboi
- Hiroaki Kitaoka
- Hiroaki Kiyokawa
- Hiroki Uehara
- Hiroshi Asano
- Hiroshi Domae
- Hiroshi Ito
- Hiroshi Meno
- Hiroshi Sugino
- Hiroshi Takaishi
- Hiroyuki Kawata
- Hisao Hara
- Hisashi Kai
- Holger Killat
- Honarpour N.
- Horacio Alberto Avaca
- Howlett J. G.
- Hugo Luquez
- Huifang Tang
- Ian Buysschaert
- Ibrahim Haldun Muderrisoglu
- Ichiro Michishita
- Ignacio Mackinnon
- Igor Kraiz
- Igor Motylev
- Igor Vakaliuk
- Iman Chouchane
- Imre Szakal
- Inder Anand
- Inder Singh
- Ioannis Barbetseas
- Ioannis Mantas
- Ioannis Styliadis
- Ira Dauber
- Irina Osipova
- Irina Semenova
- Iurii Rudyk
- Ivan Goncharov
- Ivan Majercak
- Ivana Kellnerova
- Ivaylo Vasilev
- Ivo Petrov
- Ivo Podpera
- J Dedrick Jordan
- J Russell Strader
- Jacob Eifer Moller
- Jacob Van Eck
- Jadwiga Nessler
- Jagadeesh Ganji
- James Elliott
- James Fang
- James L Januzzi
- James Rider
- James Watts
- Jan Belohlavek
- Jan Stevlik
- Jana Lukacova
- Janka Skrobakova
- Janos Tomcsanyi
- Janusz Spyra
- Jaroslaw Drozdz
- Jaroslaw Trebacz
- Jason C Legg
- Jason Glover
- Jasper Trevelyan
- Javed Butler
- Javier Segovia Cubero
- Javier Vasallo
- Jean Etienne Ricci
- Jean-Louis Georges
- Jean-Marie Lefebvre
- Jean-Michel Tartiere
- Jean-Noel Trochu
- Jean-Pierre Gueffet
- Jeffrey Martindale
- Jelena Celutkiene
- Jenica N Upshaw
- Jennifer Cook
- Jens Taggeselle
- Jeremy Cox
- Jeroen Schaap
- Jerzy Kopaczewski
- Jianjun Li
- Jindrich Spinar
- Jing Li
- Jing Yan
- Jinguo Zhang
- Jiri Krupicka
- Jiyan Chen
- Joao Carlos Braga
- Joaquin Martinez-Arraras
- Johanna Contreras
- Johannes Remmen
- John Amerena
- John Andrew Morrow
- John Atherton
- John Beltrame
- John Boehmer
- John Cleland
- John Collins
- John Corbelli
- John French
- John Groarke
- John Harris
- John Heitner
- John J V McMurray
- John Kao
- John Mignone
- John Murray
- John Parissis
- John van Hal
- Jolita Badariene
- Jonathan Howlett
- Jooyoung Shin
- Jorge Cheirif
- Jorge Leonardo Cobos Segarra
- Jorge Roberto Aiub
- Jorgen Jeppesen
- Jose Alfredo Pagola Carrasco
- Jose Augusto Ribas Fortes
- Jose Cardona
- Jose Francisco Saraiva
- Jose Luis Accini Mendoza
- Jose Luis Arenas Leon
- Jose Luis Lambert Rodriguez
- Jose Maria Arizon Del Prado
- Jose Ramon Gonzalez Juanatey
- Joseph Massaro
- Joseph Radojevic
- Joseph Rahman
- Joshua Asubiaro
- Jozef Gonsorcik
- Juan Francisco Delgado Jimenez
- Juan Jose Gomez Doblas
- Juan Londono
- Juan Luis Bonilla Palomas
- Julian Alonso Coronel Arroyo
- Julian Javier
- Juliano Cardoso
- Julio Eduardo Nuñez Villota
- Julio Ibañez
- Julio Tallet
- Jun Tanabe
- Junji Kanda
- Justin Ezekowitz
- Justin Taylor
- Kabir Yousuf
- Kahraman Cosansu
- Kalman Toth
- Kamil Zeman
- Kaoru Okishige
- Karel Peterka
- Karel Sochor
- Karen P Alexander
- Karen Sliwa
- Karl Dujardin
- Karl Heilman
- Katalin Bezzegh
- Katerina Naka
- Katsunori Kawamitsu
- Kazuhisa Mitsuo
- Keiji Ujino
- Keijiro Saku
- Keisuke Kida
- Keith Aaronson
- Keith Friedman
- Kenji Ando
- Kenji Onoue
- Kenneth Wong
- Kenshi Fujii
- Kentaro Nakamura
- Keyur Shah
- Kimberly Cruz
- Kimiaki Nagase
- Kirkwood Adams
- Klemens Ablasser
- Kodangudi Ramanathan
- Koichi Node
- Koichiro Sugimura
- Konstantin Zrazhevskiy
- Konstantinos Tsioufis
- Kotaro Numaguchi
- Kouji Kajinami
- Krzysztof Cymerman
- Kumiko Nakayama
- Kunihiko Makino
- Kurt Boman
- Kurt Huber
- Kurtz C. E. GALACTIC-HF Investigators: John R Teerlink
- Ladislav Busak
- Lana Tsao
- Lanfear D. E.
- Larry Allen
- Lars Videbaek
- Larysa Mishchenko
- Larysa Vasilyeva
- Laszlo Mark
- Laszlo Nagy
- Laura Jordan Martinez
- Laurie Letarte
- Lawrence Galitz
- Lawrence J Lesko
- Legg J. C.
- Leighton Kearney
- Lenka Spinarova
- Leonard Pianko
- Leonardo Macias
- Leonardo Novaretto
- Leonid Pimenov
- Leonid Rudenko
- Leonid Voronkov
- Leopoldo Soares Piegas
- Lesley Burgess
- Lesya Rasputina
- Li J.
- Libor Nechvatal
- Lidia Ana Zytynski Moura
- Lidia Pawlowicz
- Lilia Luz Lobo Marquez
- Lilia Nigro Maia
- Lilia Schiavi
- Liliana Nicolosi
- Lily Zhang
- Lisa Mielniczuk
- Liudmyla Alieksieieva
- Lixin Jiang
- Llyod Stahl
- Lokesh Chandra
- Louis Van Zyl
- Luanda Grazette
- Lubomir Antalik
- Luc Pierard
- Lucie Sharpsten
- Lucyna Lenartowska
- Luis Almenar Bonet
- Luis Beck da Silva Neto
- Luis de la Fuente Galan
- Luis Eduardo Echeverria
- Luis Eduardo Echeverria
- Luis Horacio Atehortua Lopez
- Luis Martinez
- Luis Oliveira
- Luis Santos
- Lund M.
- Lutfu Bekar
- Lutz Frankenstein
- Macdonald P.
- Maciej Zabowka
- Madhusudhan Pamganamamula
- Magnus Peterson
- Mahazarin Ginwalla
- Makoto Nakahama
- Makoto Usui
- Malgorzata Konieczynska
- Malgorzata Lelonek
- Malik F. I.
- Mamoru Manita
- Manoel Canesin
- Manohara Senaratne
- Manuel Bouza
- Manuel Eduardo Rodriguez Venegas
- Manuel Martinez-Selles D Oliveira Soares
- Manuel Odin De Los Rios Ibarra
- Marat Ezhov
- Marc Simon
- Marcelo Alejandro Garrido
- Marcin Szczasny
- Marco Metra
- Marcos Amuchastegui
- Marcos Raul Litvak Bruno
- Marcus Mittag
- Marcus Sandri
- Marcus Stoddard
- Marcus Vinicius Simoes
- Mareev V.
- Marek Houra
- Marek Piatek
- Margarita Gertrudis Vejar Jalaf
- Maria Alexandra Arias Mendoza
- Maria Cristina Schnettler Cid
- Maria Dorobantu
- Maria Frigerio
- Maria Generosa Crespo Leiro
- Maria Helena Vidotti
- Maria Leonor Parody
- Maria Sanali Paiva
- Maria Sitnikova
- Maria Teresa Blasco Peiro
- Maria Tzekova
- Mariel Rivero
- Mariela Rasmussen
- Marilena Renata Spiridon
- Mario Vega
- Mario Villoch
- Mario Yanez Hidalgo
- Marisa Crespo Leiro
- Marisa Orgera
- Mariusz Kafara
- Mark Abelson
- Mark Ramos
- Mark Smith
- Mark Zucker
- Martin Berk
- Martin Huelsmann
- Martin LeWinter
- Marvin A Konstam
- Mary Lynch
- Masahiro Ishikawa
- Masahiro Suzuki
- Masaki Yoshikawa
- Masanori Asakura
- Masaru Yuge
- Masayoshi Ajioka
- Masayuki Doi
- Masuki Mori
- Mateusz Sidor
- Mathue Baker
- Matt Wilkett
- Matteo Di Biase
- Matthew Janik
- Matthew Wheeler
- Matthias Dupont
- Maurizio Volterrani
- Mayanna Lund
- McMurray J. J. V.
- Mehmet Birhan Yilmaz
- Mehmet Birhan Yilmaz
- Mehmet Duzenli
- Mehrdad Ariani
- Melchor Alpizar Salazar
- Melvin Martinez-Castrillon
- Mesut Demir
- Metra M.
- Michael Boehm
- Michael Böhm
- Michael Felker G.
- Michael Hartleib
- Michael Koren
- Michael Kwan
- Michael Magro
- Michael Miyamoto
- Michael Pham
- Michael Radin
- Michal Cepelak
- Michel Galinier
- Michel Ovize
- Michele Hamilton
- Michele Senni
- Miguel Alfredo Moncada Corredor
- Miguel Angel Hominal
- Miguel Urina Triana
- Mikhail Kotelnikov
- Mikhail Voevoda
- Milan Gupta
- Mio Ebato
- Mircea Ioachim Popescu
- Mirta Diez
- Mitsuhiro Shimomura
- Mitsuru Tsujimoto
- Mitsutaka Yamamoto
- Mohammad Abuannadi
- Mohan Babapulle
- Momomura S.
- Monica Lopez Pareja
- Mori Krantz
- Mukesh Sharma
- Munir Janmohamed
- Muriel Salvat
- Mustafa Tuncer
- Mustafa Vural
- Mykola Rishko
- Mykola Stanislavchuk
- Nabil Dib
- Nadia Giannetti
- Naeem Tahirkheli
- Nampalli Vijay
- Nancy Sweitzer
- Nandini Nair
- Nandkishore Ranadive
- Naoki Sato
- Naoki Watanabe
- Narimon Honarpour
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- Valerio Zaca
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- Vladimir Cech
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- Vladimir Salukhov
- Vladislav Mitrokhin
- Voors A. A.
- Vyacheslav Mareev
- Vyacheslav Ryabov
- W Schuyler Jones
- Wael AboAuda
- Wakaya Fujiwara
- Walter Abhayaratna
- Walter Droogne
- Walter Hermans
- Wataru Shimizu
- Wayne Gray
- Weiheng Wu
- Weimar Kunz Barroso de Souza
- Weimin Li
- Wentang Niu
- Wilder Castaño Osorio
- William Anderson
- William Herzog
- William Nelson
- William Randall
- Wissam Khalife
- Xin Fu
- Xuelian Zhang
- Xuming Yang
- Yafei Mi
- Yajun Han
- Yang Zheng
- Yanling Qu
- Yann Rosamel
- Yasuchika Takeishi
- Yasuhiro Maejima
- Yasuki Kihara
- Yasunori Ueda
- Yasuo Okumura
- Yasushi Sakata
- Yevgeniya Svishchenko
- Yi Wang
- Yilmaz M. B.
- Yinjun Li
- Yorihiko Higashino
- Yoshihiko Saito
- Yoshiki Hata
- Yoshinori Yasaka
- Yoshitoshi Urabe
- Yu Wei
- Yuemin Sun
- Yugang Dong
- Yuhui Zhang
- Yuji Nakazato
- Yukihiko Momiyama
- Yukihito Sato
- Yukiko Morita
- Yuksel Cavusoglu
- Yuqing Zhang
- Yurii Lymar
- Yuriy Mostovoy
- Yury Lukyanov
- Yury Shvarts
- Yutaka Akatsuka
- Yves Pesant
- Zannad F.
- Zbigniew Bednarkiewicz
- Zbigniew Chmielak
- Zbigniew Gola
- Zbigniew Kalarus
- Zbigniew Pijanowski
- Zbynek Pozdisek
- Zdenek Coufal
- Zdenek Klimsa
- Zdenek Monhart
- Zehra Lale Koldas
- Zerrin Yigit
- Zhanna Kobalava
- Zhanquan Li
- Zhaoping Li
- Zhe Zheng
- Zhenyu Yang
- Zhifang Wang
- Zoltan Laszlo
- Zsolt Zilahi
- Zuyi Yuan
- Zuzana Motovska
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2021
- Field of study
BACKGROUND The selective cardiac myosin activator omecamtiv mecarbil has been shown to improve cardiac function in patients with heart failure with a reduced ejection fraction. Its effect on cardiovascular outcomes is unknown. METHODS We randomly assigned 8256 patients (inpatients and outpatients) with symptomatic chronic heart failure and an ejection fraction of 35% or less to receive omecamtiv mecarbil (using pharmacokinetic-guided doses of 25 mg, 37.5 mg, or 50 mg twice daily) or placebo, in addition to standard heart-failure therapy. The primary outcome was a composite of a first heart-failure event (hospitalization or urgent visit for heart failure) or death from cardiovascular causes. RESULTS During a median of 21.8 months, a primary-outcome event occurred in 1523 of 4120 patients (37.0%) in the omecamtiv mecarbil group and in 1607 of 4112 patients (39.1%) in the placebo group (hazard ratio, 0.92; 95% confidence interval [CI], 0.86 to 0.99; P = 0.03). A total of 808 patients (19.6%) and 798 patients (19.4%), respectively, died from cardiovascular causes (hazard ratio, 1.01; 95% CI, 0.92 to 1.11). There was no significant difference between groups in the change from baseline on the Kansas City Cardiomyopathy Questionnaire total symptom score. At week 24, the change from baseline for the median N-terminal pro-B-type natriuretic peptide level was 10% lower in the omecamtiv mecarbil group than in the placebo group; the median cardiac troponin I level was 4 ng per liter higher. The frequency of cardiac ischemic and ventricular arrhythmia events was similar in the two groups. CONCLUSIONS Among patients with heart failure and a reduced ejection, those who received omecamtiv mecarbil had a lower incidence of a composite of a heart-failure event or death from cardiovascular causes than those who received placebo. (Funded by Amgen and others; GALACTIC-HF ClinicalTrials.gov number, NCT02929329; EudraCT number, 2016 -002299-28.)
The Changing Landscape for Stroke\ua0Prevention in AF
- Author
- Abban Dzifa
- Abdul Nasser
- Abelson Mark
- Ackermann Alan
- Adams Fran
- Adams Luthando
- Adrag\ue3o Pedro
- Ageno Walter
- Aggarwal Rajesh
- Agosti Sergio
- Aguilar Linares Julio Alberto
- Aguilar Francisco
- Aguinaga Luis
- Ahmad Zia
- Ainsworth Paul
- Al Ghalayini Kamal
- Al Ismail Saad
- Al Mahameed Soufian
- Al-Dallow Raed
- Al-Joundi Tammam
- Al-Obaidi Mohamed
- Al-Zoebi Ayham
- Alasfar Abdelfatah
- Alawwa Abdul
- Alderson Lisa
- Alexopoulos Dimitrios
- Ali Abdullah
- Ali Malik
- Aliyar Pareed
- Almassi Hossein
- Almuti Khalid
- Alshehri Mohamed
- Altmann Ute
- Alves Alvaro Rabelo
- Amara Walid
- Amelot Mathieu
- Amjadi Nima
- Ammirati Fabrizio
- Andrawis Nabil
- Angela Koh Su Mei
- Angoulvant Denis
- Annoni Giorgio
- Ansalone Gerardo
- Antonescu Sorin Alexandru
- Ariani Mehrdad
- Arias Juan Carlos
- Armero S\ue9bastien
- Arora Chander
- Arora Rohit
- Ashcraft William
- Aslam M. Shakil
- Astesiano Alfredo
- Audouin Philippe
- Augenbraun Charles
- Aydin S.
- Azar Rabih
- Azim Abul
- Aziz Shahid
- B\uf8hmer Ellen
- Backes Luciano Marcelo
- Baig Mirza
- Bains Suchdeep
- Bakbak Asaad
- Baker Seth
- Bakhtiar Karim
- Bala Richard
- Banayan Jonathan
- Bandh Stellan
- Bando Shigenobu
- Banerjee Subhash
- Bank Alan
- Bar\uf3n Gonzalo
- Barbarash Olga
- Barr Craig
- Barrera Carlos
- Bartels Dorothee B.
- Barton John
- Baula Giovanni
- Bayeh Hamid
- Bazargani Nooshin
- Behrens Steffen
- Bell Alan
- Benezet-Mazuecos Juan
- Benhalima Bouziane
- Berdagu\ue9 Philippe
- Berg van den B.J.
- Bergen van P.F.M.M.
- Berngard Edvard
- Bernstein Richard
- Berrospi Percy
- Berti Sergio
- Bertomeu Vicente
- Berz Andrea
- Bettencourt Paulo
- Betzu Robert
- Beyer-Westendorf Jan
- Bhagwat Ravi
- Black Toby
- Blanco Ibaceta Jorge Hugo
- Bloom Stephen
- Blumberg Edwin
- Bo Mario
- Bockisch Valerie
- Bongiorni Maria Grazia
- Boriani Giuseppe
- Borret Mariano Ruiz
- Bosch Ralph
- Boswijk D.J.
- Bott Jochen
- Bottacchi Edo
- Brandes Axel
- Bratland Bj\uf8rn
- Brautigam Donald
- Breton Nicolas
- Briones Ignacio Rodriguez
- Brkljacic Diana Delic
- Brouwers P.J.A.M.
- Browne Kevin
- Bruguera Jordi
- Brunehaut Myriam
- Brunschwig Claude
- Bryan Yan Ping Yen
- Buathier Herv\ue9
- Buenostro Gabriel Contreras
- Buhl Aur\ue9lie
- Bullinga John
- Butcher Kenneth
- Cabrera Honorio Jose Walter
- Caccavo Alberto
- Cadinot Didier
- Cai Shanglang
- Caiedo Carolina Guevara
- Calin Podoleanu Cristian Gheorghe
- Calvi Valeria
- Camm John
- Candeias Rui
- Cao Phai G\ue9rald Phan
- Capo James
- Capucci Alessandro
- Cardoso Juliano Novaes
- Carlson Brian
- Carvalho Paula
- Cary Susanna
- Casanova Rene
- Casu Gavino
- Cattan Simon
- Cavallini Claudio
- Cayla Guillaume
- Cha Kwang Soo
- Cha Tae Joon
- Chaaban Said
- Chae Jei Keon
- Challappa Krishnan
- Chand Sunil
- Chandrashekar Harinath
- Chang Mark
- Charbel Paul
- Chartier Ludovic
- Chatterjee Kausik
- Cheema Aamir
- Chen Shih-Ann
- Chevallereau Pierre
- Chiang Fu-Tien
- Chiarella Francesco
- Chih-Chan Lin
- Cho Yong Keun
- Choi Dong Ju
- Chouinard Guy
- Chow Hoi Fan
- Chreih Rami Mihail
- Chrysos Dimitrios
- Chumakova Galina
- Cieza-Lara Tomas
- Ciobotaru Vlad
- Cislowski David
- Citerne Olivier
- Claus Matthias
- Clay Anthony
- Clifford Piers
- Cocina Emilio Gonzalez
- Cohen Andrew
- Cohen Serge
- Colivicchi Furio
- Collins R\uf3n\ue1n
- Compton Steve
- Connors Sean
- Conti Alberto
- Coodley Gregg
- Cooper Martin
- Corbett Lynn
- Corey Oran
- Coronel Juli\ue1n
- Corrigan John
- Cotrina Pereyra Rosa Ysabel
- Cottin Yves
- Coutu Benoit
- Cracan Aurel
- Crean Peter
- Crenshaw James
- Crijns H.J.G.M.
- Crump Charles
- Cucher Fred
- Cudmore David
- Cui Lianqun
- Culp John
- D'Souza Anthony
- Daniel Oh Chia Theng
- Danny
- Darius Harald
- Dary Patrick
- Dascotte Olivier
- Dauber Ira
- Davee Thomas
- Davies Ruth
- Davis Gershan
- Davy Jean-Marc
- Dayer Mark
- De La Briolle Axel
- de Los Rios Ibarra Manuel Odin
- de Mora Manuel
- de Souza Olga Ferreira
- De Teresa Eduardo
- De Wolf Luc
- Decoulx Eric
- Deepak Sasalu
- Defaye Pascal
- Del-Carpio Munoz Freddy
- Deluche Laurent
- Destrac Sylvain
- Deumite N.Joseph
- Di Legge Silvia
- Dibon Olivier
- Diemberger Igor
- Diener Hans-Christoph
- Dillinger Jean
- Dion\uedsio Pedro
- Dotani Imran
- Dotcheva Elena
- Duarte Vera Yan Carlos
- Dubner Sergio J.
- Dubrey Simon
- Ducrocq Xavier
- Dupljakov Dmitry
- DuThinh Vuong
- Dutra Oscar Pereira
- Dutta Dipankar
- Duvilla Nathalie
- Dy Johnny
- Dziewas Rainer
- Eaton Charles
- Eaves William
- Ebinger Matthew
- Eck van J.W.M.
- Edwards Tim
- Egocheaga Isabel
- Ehrlich Clifford
- Eisenberg Steven
- El Hallak Abdel
- El Jabali Adnan
- El Mahmoud Rami
- El Shahawy Mahfouz
- El-Hamdani Mehiar
- El-Sayed Hassan
- Eldadah Zayd
- Elghelbazouri Fouad
- Elhag Omar
- Elias Darlene
- Ellery Adam
- Elsaesser Amelie
- Elvan A.
- Erickson Bernard
- Espaliat Eric
- Essandoh Louis
- Everington Tamara
- Evonich Rudolph
- Ezhov Andrey
- F\ue1cila Lorenzo
- Farsad Ramin
- Fayard Maxime
- Fedele Francesco
- Ferreira Daniel
- Ferrier Anna
- Finsen Alexandra
- First Brian
- Fisher Raymond
- Floyd John
- Folk Thomas
- Fonseca Catarina
- Fonseca Luisa
- Fonteles Ritt Luiz Eduardo
- Forman Steven
- Forsgren Magnus
- Foster Malcolm
- Foster Nathan
- Frais Michael
- Frandsen Brad
- Frapp\ue9 Thierry
- Freixa Ramon
- French William
- Freydlin Marina
- Frickel Siegfried
- Fruntelata Ana Gabriela
- Fujii Shigeru
- Fujino Yusuke
- Fukunaga Hiroshi
- Furukawa Yutaka
- G\uf6tte Andreas
- Gabelmann Matthias
- Gabris Michael
- Gadsb\uf8ll Niels
- Galin Pavel
- Galinier Michel
- Ganim Ricky
- Garcia Ronnie
- Gartenlaub Olivier
- Genz Conrad
- Georger Fr\ue9d\ue9ric
- Georges Jean-Louis
- Georgeson Steven
- Ghanbasha Ali
- Giedrimas Evaldas
- Gierba Mariusz
- Gillespie Eve
- Giniger Alberto
- Gkotsis Alexandros
- Gmehling Joachim
- Gniot Jacek
- Goethals Peter
- Goldberg Ronald
- Goldmann Britta
- Goldscher David
- Golitsyn Sergey
- Gomes Ferreira Luis Gustavo
- Gomez Lopez Efrain Alonso
- Gomez Mesa Juan Esteban
- Gonzalez Efrain
- Gorbunov Vladimir
- Gordon Brian
- Gorka Herv\ue9
- Gornick Charles
- Gorog Diana
- Goss Franz
- Goube Pascal
- Goudevenos Ioannis
- Goulden Dudley
- Gr\uf6nefeld Gerian
- Graham Brett
- Grande Angel
- Greco Cesare
- Green Martin
- Greer Gerald
- Gremmler Uwe
- Grena Paul
- Grinshstein Yuriy
- Grond Martin
- Gronda Edoardo
- Grondin Francois
- Groot de J.R.
- Guardigli Gabriele
- Guarnieri Thomas
- Guignier Alexandre
- Gulizia Michele
- Gumbley Michael
- Gupta Dhiraj
- Hack Terrence
- Haerer Winfried
- Hakas Joseph
- Hall Christian
- Halperin Jonathan L.
- Hampsey James
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- Hanbali Basel
- Handel Franklin
- Hargrove Joe
- Hargroves David
- Harris Kenneth
- Hartley David
- Haruna Tetsuya
- Hata Yoshiki
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- Healey Jeff
- Hearne Steven
- Heggelund Geir
- Hemels M.E.W.
- Hemery Yann
- Henein Sam
- Henz Benhur
- Her Sung-Ho
- Hermany Paul
- Hern\ue1ndez Norberto Matadamas
- Hernandes Mauro Esteves
- Higashino Yorihiko
- Hill Michael
- Hisadome Tetsuo
- Hishida Eiji
- Hitchcock James
- Hoffer Etienne
- Hoghton Matthew
- Holmes Clare
- Hong Suk Keun
- Houppe Nousse Marie-Paule
- Howard Victor
- Hsu Li Fern
- Huang Chi-Hung
- Huckins David
- Huehnergarth Kier
- Huisman Menno V.
- Huizenga A.
- Huntley Richard
- Hussein Gamal
- Hwang Gyo-Seung
- Igbokidi Oyidie
- Iglesias Ignacio
- Ikpoh Margaret
- Imberti Davide
- Ince H\ufcseyin
- Indolfi Ciro
- Ionova Tatiana
- Ip John
- Irles Didier
- Iseki Harukazu
- Ismail Younus
- Israel Noah
- Isserman Steven
- Iteld Bruce
- Ivanchura Galina
- Iyer Ramakrishnan
- Iyer Venkat
- Iza Villanueva Ruben Omar
- J\ue4ger Frank
- Jackson-Voyzey Ewart
- Jaffrani Naseem
- Jain Manish
- James Martin
- Jamon Yann
- Jang Sung Won
- Jarmukli Nabil
- Jeanfreau Robert
- Jenkins Ronald
- Jiang Heng
- Jiang Nan
- Jiang Tiemin
- Jiang Xianyan
- Jimenez Javier
- Jobe Robert
- Joffe Ian
- Johansson Bengt
- Jones Nick
- Jos\ue9 Roberto Chuquiure Valenzuela Eduardo Juli\ue1n
- Jouve Bernard
- Juanatey Carlos Gonzalez
- Jundi Mayar
- Jung Byung Chun
- Jung Kyung Tae
- Jung Werner
- K\uf6hrmann Martin
- K\ufcmler Thomas
- K\ufcppers Achim
- Kabbani Samer
- Kabour Ameer
- Kafkala Chrystalenia
- Kajiwara Koji
- Kalan Marica Bracic
- Kalinina Larisa
- Kampus Priit
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- Kastrup Andreas
- Katsivas Apostolos
- Kaufman Elizabeth
- Kawai Kazuya
- Kawajiri Kenji
- Kazmierski John
- Keeling Phil
- Kerfes Galal Ali
- Kerr Saraiva Jos\ue9 Francisco
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- Ketova Galina
- Khaira Ajit
- Khalid Muhammad
- Khludeeva Elena
- Khripun Aleksey
- Kim Dae Kyeong
- Kim Doo Il
- Kim Jeong Su
- Kim Jin bae
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- Kim Ki Seok
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- Kim Young-Hoon
- Kinova Elena
- Klein Alexander
- Kleinschnitz Christoph
- Kmetzo James
- Kneller G. Larsen
- Knezevic Aleksandar
- Koch Stanley
- Koenig Kai
- Koons Jay
- Korabathina Ravikiran
- Korennova Olga
- Koschutnik Martin
- Kosinski Edward
- Kovacic Dragan
- Kowalczyk Jacek
- Koziolova Natalya
- Kragten J.A.
- Krause Lars Udo
- Kreidieh Imad
- Krenning B.J.
- Krishnaswamy Kannappan
- Krysiak Waldemar
- Kuck Karl-Heinz
- Kumar Somnath
- Kuniss Malte
- Kuo Jen-Yuan
- Kurrelmeyer Karla
- Kwan Tak
- Kyo Eisho
- L\uf3pez-Send\uf3n Jos\ue9
- Labovitz Arthur
- Lacroix Alain
- Lam Andy
- Lanas Zanetti Fernando Tomas
- Landau Charles
- Landini Giancarlo
- Lang Wilfried
- Larsen Torben Bjerregaard
- Laske Volker
- Lavandier Karine
- Law Nicki
- Lawrence Wong Ka Sing
- Lee Daniel
- Lee Moon Hyoung
- Leit\ue3o Ana
- Lejay Dominique
- Lelonek Malgorzata
- Lenarczyk Radoslaw
- Leprince Patrick
- Lequeux Benoit
- Leschke Matthias
- Ley Nicolas
- Li Weihua
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- Li Yansheng
- Li Zhanquan
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- Liang Jianqiu
- Lieber Ira
- Lillestol Michael
- Limon Rodriguez Ramon Horacio
- Lin Hailong
- Lip Gregory
- Lip Gregory Y.H.
- Litchfield Jennifer
- Liu Feng
- Liu Wenhui
- Liu Xuebo
- Liu Yalin
- Liu Zhitao
- Llamas Esperon Guillermo Antonio
- Llisterri Jose Luis
- Lo Eric
- Lo Ted
- Lobos Jose Maria
- Lodde Bernhard-Paul
- Loiselet Philippe
- Lorga Filho Adalberto Menezes
- Lori Ido
- Luo Ming
- Lupovitch Steven
- Lyrer Philippe
- M\ufcgge Andreas
- Ma Chang Sheng
- Ma Changsheng
- Ma Genshan
- Ma Hong
- Madariaga Irene
- Maeno Koji
- Magnin Dominique
- Mahmood Shahid
- Mahood Karen
- Maid Gustavo
- Mainigi Sumeet
- Makaritsis Konstantinos
- Maldonado Villalon Jos\ue9 Arturo
- Malhotra Rohit
- Malik Amir
- Mallecourt Catherine
- Mallik Rajiv
- Manning Rickey
- Manolis Athanasios
- Mantas Ioannis
- Manzur Jattin Fernando Gabriel
- Mar\uedn Francisco
- Marcionni Niccolo'
- Marin Javier Aguila
- Martinez Jorge
- Martinez Luis
- Maskova Petra
- Matskeplishvili Simon
- Matsuda Katsuhiro
- Mavri Alenka
- May Erik
- Mayer Nolan
- Mazon Pilar
- McClure John
- McCormack Terry
- McGarity William
- McGuire Michael
- McIntyre Hugh
- McLaughlin Paul
- McLaurin Brent
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- Mehta Paresh
- Mehzad Reza
- Meinel Andreas
- Melandri Francesco
- Mena Amparo
- Meno Hirosi
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- Metcalf Kneale
- Meyer Beat
- Miarka Jacek
- Mibach Frank
- Michalski Dominik
- Michel Patrik
- Mikdadi Ghiath
- Mikhail Magdy
- Mikus Milan
- Milicic Davor
- Militaru Constantin
- Miller Gary
- Milonas Christos
- Minescu Bogdan
- Mintale Iveta
- Miralles Aur\ue9lien
- Mirault Tristan
- Mistry Dinesh
- Mitchell George
- Miu Nicoleta Violeta
- Miyamoto Naomasa
- Moccetti Tiziano
- Mohammed Akber
- Molina de Salazar Dora Ines
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- Moodley Rajendra
- Moore Roger
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- Morka Jacek
- Moschos Nikitas
- Mota Gomes Marco Ant\uf4nio
- Moura Jorge Jose Carlos
- Mousallem Nicolas
- Moya Angel
- Mulhearn Thomas
- Muller Jean-Joseph
- Muresan Carmen Manuela
- Muse Derek
- Musial Wlodzimierz
- Musumeci Francesco
- Nadar Venkatesh
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- Nair Priya
- Nakagawa Hidemitsu
- Nakamura Yuichiro
- Nakayama Toru
- Nam Ki-Byeong
- Napalkov Dmitry
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- Nayak Hemal
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- Neiman James
- Nerheim Pamela
- Neuenschwander Fernando Carvalho
- Nica Violeta Cindea
- Nishida Kunihiro
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- Nor Azlisham Mohd
- Novikova Tatiana
- Novo Salvatore
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- Nsah Emmanuel
- Nunez Fragoso Juan Carlos
- Nyvad Ole
- O'Donnell Martin
- O'Donnell Philip
- O'Hara Gilles
- Oh Dong Jin
- Oh Yong Seog
- Oikonomou Kostas
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- Olivari Zoran
- Oliver Richard
- Olympios Christoforos
- Osborne John
- Osca Joaquin
- Osman Raed
- Osunkoya Abayomi
- Padanilam Benzy
- Panchenko Elizaveta
- Pandey A. Shekhar
- Paquette Miney
- Paraschos Alexander
- Pardell Herbert
- Park Hyung Wook
- Park Jong Sung
- Parkash Ratika
- Parker Ian
- Parrens Eric
- Parris Robert
- Pascual Carlos Rodr\uedguez
- Passamonti Enrico
- Patel Jaydutt
- Patel Rajesh
- Pentz William H.
- Pereira Jardim Cesar Augusto
- Persic Viktor
- Perticone Francesco
- Peters Patrick
- Petkar Sanjiv
- Pezo Luis Felipe
- Pham David
- Phlaum Stephen
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- Polasek Petr
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- Polo Jose
- Poock James
- Poppert Holger
- Porro Yamile
- Pose Antonio
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- Poulard Jean-Ernst
- Pouzar Joe
- Povolny Petr
- Pozzer Domingo
- Pras Athanasios
- Prasad Neeraj
- Prevot S\ue9bastien
- Protasov Konstantin
- Prunier Laurent
- Puleo John
- Pye Maurice
- Qaddoura Fatma
- Quedillac Jean-Michel
- Quintana Antonio Garcia
- Raev Dimitar
- Rahimi Sidiqullah
- Raisaro Arturo
- Rama Bhola
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- Randall Katie
- Ranjith Naresh
- Raposo Nuno
- Rashid Haroon
- Raters Christa
- Rauch-Kroehnert Ursula
- Rebane Thomas
- Regner Stefan
- Renzi Michael
- Reyes Rocha Miguel Agustin
- Reyes Humberto Rodriguez
- Reza Shabbir
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- Rickner Kyle
- Rieker Werner
- Rigo Fausto
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- Roelke Marc
- Roman Mark
- Romeo Francesco
- Ronner E.
- Ronziere Thomas
- Rooyer F.A.
- Rosenbaum David
- Roth Sherryn
- Rothman Kenneth J.
- Rozkova Nadezda
- Rubacek Miroslav
- Rubalcava Frank
- Rubanenko Olesya
- Rubin Andrew
- Rybak Karin
- Sabbour Hani
- Sakai Tetsuo
- Salacata Abraham
- Salecker Ilsbe
- Salem Adrien
- Salfity Marwan
- Salguero Rafael
- Salvioni Alessandro
- Samson Mercedes
- Sanchez Gregorio
- Sandesara Chirag
- Santana Antonio Mart\uedn
- Santos Jos\ue9 Ferreira
- Saporito Wladmir Faustino
- Sasaoka Taishi
- Sattar Payman
- Savard Daniel
- Scala Pierre-Jean
- Scemama Jacques
- Sch\uf6n Norbert
- Schaupp Thierry
- Schellinger Peter
- Scherr Carlos
- Schmitz Bettina
- Schmitz Karl-Heinz
- Schmitz Lisa
- Schnitzler Robert
- Schnupp Steffen
- Schoeniger Peter
- Schuster Stefan
- Schwimmbeck Peter
- Seamark Clare
- Seebass Ruediger
- Seidl Karl-Heinz
- Seidman Barry
- Sek Jaroslaw
- Sekaran Lakshmanan
- Seko Yoshinori
- Sepulveda Varela Pablo Andres
- Sevilla Bego\uf1a
- Shah Aman
- Shah Anil
- Shah Neerav
- Shah Vinay
- Shanes Jeffrey
- Sharareh Ali
- Sharma Vijay Kumar
- Shaw Louise
- Shimizu Yutaka
- Shimomura Hideki
- Shin Dong Gu
- Shin Eun-Seok
- Shite Junya
- Shoukfeh Mohammad
- Shoultz Charles
- Silver Frank
- Sime Iveta
- Simmers T.A.
- Singal Dinesh
- Singh Narendra
- Siostrzonek Peter
- Sirajuddin Mohiburrahman
- Skeppholm Mika
- Smadja Didier
- Smith David
- Smith Richard
- Soda Hassan
- Sofley C. Wilson
- Sokal Adam
- Sotolongo Rodolfo
- Sparby Jon Arne
- Spinar Jindrich
- Sprigings David
- Spyropoulos Alex
- Stakos Dimitrios
- Steinberg Alon
- Steinwender Clemens
- Stergiou Georgios
- Stites H. William
- Stoikov Anastas
- Strasser Ruth
- Streb Witold
- Styliadis Ioannis
- Su Guohai
- Su Xi
- Suarez Rafael Martin
- Sudnik Wanda
- Sueyoshi Atsushi
- Sukles Kai
- Sun Li
- Suneja Randeep
- Svensson Peter
- Szavits-Nossan Janko
- Taggeselle Jens
- Takagi Yuichiro
- Takhar Amrit
- Tallet Julio
- Tamm Angelika
- Tanaka Katsumi
- Tanaka Shozo
- Tang Aylmer
- Tang Sherman
- Tassinari Tiziana
- Tayama Shinji
- Tayebjee Muzahir
- Tebbe Ulrich
- Teixeira Jose
- Tesloianu Dan Nicolae
- Tessier Pascal
- Teutsch Christine
- The S.H.K.
- Thevenin J\ue9rome
- Thomas Harold
- Timsit Serge
- Topkis Robert
- Torosoff Mikhail
- Touze Emmanuel
- Traissac Thalie
- Trendafilova Elina
- Troyan Barry
- Tsai Wenchi Kevin
- Tse Hung Fat
- Tsutsui Hiroshi
- Tsutsui Takashi
- Tuininga Y.S.
- Turakhia Minang
- Turk Samir
- Turner Wayne
- Tveit Arnljot
- Twiddy Shannon
- Tytus Richard
- Ukrainski Gerald
- Valdovinos Chavez Salvador Bruno
- Van De Graaff Eric
- Vanacker Peter
- Vardas Panagiotis
- Vargas Michael
- Vassilikos Vassilios
- Vazquez Juan
- Venkataraman Asok
- Verdecchia Paolo
- Vester Ernst G\ufcnter
- Vial Hubert
- Vicenzo de Paola Angelo Amato
- Vinereanu Dragos
- Vlastaris Anthony
- Vogel Craig
- vom Dahl J\ufcrgen
- von Mering Matthias
- Vora Kishor
- Wakefield Paul
- Walia Jasjit
- Walter Thomas
- Wang Feng
- Wang Kuo-Yang
- Wang Mingsheng
- Wang Ningfu
- Wang Xinhua
- Wang Zulu
- Watanabe Kouki
- Wei Jeanne
- Weimar Christian
- Weinrich Renate
- Wen Ming-Shien
- Wheelan Kevin
- Wicke Jens
- Wiemer Marcus
- Wild Beate
- Wilke Andreas
- Willems Stephan
- Williams David
- Williams Marcus
- Winkler Andreas
- Wirtz Jost Henner
- Witzenbichler Bernhard
- Wong Brian
- Wong Danny H.K.
- Wozakowska-Kaplon Beata
- Wu Shulin
- Wu Zhaohui
- Wyatt Nell
- Xu Xiangdong
- Xu Yong
- Yamada Akira
- Yamamoto Kazuya
- Yamanoue Hiroki
- Yamashita Takeshi
- Yang Tianlun
- Yang Yanmin
- Yao Jing
- Yarlagadda Chakri
- Yeh Kuo-Ho
- Yotov Yoto
- Yvorra Serge
- Zahn Ralf
- Zamorano Jos\ue9
- Zanini Roberto
- Zarich Stuart
- Zebrack James
- Zenin Sergei
- Zeuthen Elisabeth Louise
- Zhang Dadong
- Zhang Donghui
- Zhang Huanyi
- Zhang Quansan
- Zhang Xingwei
- Zhao Shuiping
- Zhao Xinwen
- Zheng Qiangsun
- Zheng Yang
- Zhou Jian
- Zhou Jing
- Ziekenhuis Antonius
- Zimmermann Rainer
- Zimmermann Sergio Luiz
- Zint Kristina
- Zuhairy Hamed M.
- Zukerman L. Steven
- Zwaan van der C.
- Publication venue
- Publication date
- 01/01/2017
- Field of study
Correction to: Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice: GLORIA-AF Registry
- Author
- Abban Dzifa Wosornu
- Abdul Nasser
- Abud Atilio Marcelo
- Adams Fran
- Addala Srinivas
- Adragão Pedro
- Ageno Walter
- Aggarwal Rajesh
- Agosti Sergio
- Agostoni Piergiuseppe
- Aguilar Francisco
- Aguinaga Luis
- Ahmed Jameel
- Aiello Allessandro
- Ainsworth Paul
- Aiub Jorge Roberto
- Al-Dallow Raed
- Alderson Lisa
- Alexopoulos Dimitrios
- Aliyar Pareed
- Almeida Luísa Fonseca
- Alonso David
- Alvaro Feliz
- Amado José
- Amara Walid
- Amelot Mathieu
- Amjadi Nima
- Ammirati Fabrizio
- Andrade Marianna
- Andrawis Nabil
- Annoni Giorgio
- Ansalone Gerardo
- Ariani M. Kevin
- Arias Juan Carlos
- Armero Sébastien
- Arora Chander
- Asensi Joaquín Osca
- Aslam Muhammad Shakil
- Asselman M.
- Audouin Philippe
- Augenbraun Charles
- Ayala Carlos Antero Chavez
- Aydin S.
- Ayryanova Ivaneta
- Aziz Emad
- Backes Luciano Marcelo
- Badings E.
- Bagni Ermentina
- Baker Seth
- Bala Richard
- Baldi Antonio
- Bando Shigenobu
- Banerjee Subhash
- Bank Alan
- Barr Craig
- Bartlett Maria
- Basic Kes Vanja
- Baula Giovanni
- Behrens Steffen
- Bell Alan
- Benedetti Raffaella
- Benhalima Bouziane
- Berg J.
- Bergler-Klein Jutta
- Berneau Jean-Baptiste
- Bernstein Richard
- Berrospi Percy
- Berti Sergio
- Berz Andrea
- Best Elizabeth
- Bettencourt Paulo
- Betzu Robert
- Bhagwat Ravi
- Bhatta Luna
- Biscione Francesco
- Bisignani Giovanni
- Black Toby
- Bloch Michael
- Bloom Stephen
- Blumberg Edwin
- Bo Mario
- Bodes Rafael Salguero
- Bollmann Andreas
- Bongiorni Maria Grazia
- Boriani Giuseppe
- Boswijk D.
- Bott Jochen
- Bottacchi Edo
- Bradman Drew
- Brautigam Donald
- Breton Nicolas
- Briones Ignacio Rodriguez
- Brkljacic Diana Delic
- Brouwers P.
- Browne Kevin
- Bruni A.
- Brunschwig Claude
- Buathier Hervé
- Buenostro Gabriel Contreras
- Buhl Aurélie
- Bullinga John
- Bøhmer Ellen
- Cabrera Jose Walter
- Caccavo Alberto
- Cai Shanglang
- Caine Sarah
- Calvi Valeria
- Calò Leonardo
- Campos Rodrigo Noronha
- Candeias Rui
- Capuano Vincenzo
- Capucci Alessandro
- Caputo Ronald
- Cardona Francisco
- Carolei Antonio
- Carreño Susana
- Carvalho Paula
- Cary Susanna
- Casu Gavino
- Cavallini Claudio
- Cayla Guillaume
- Celentano Aldo
- Cha Kwang Soo
- Cha Tae-Joon
- Chae Jei Keon
- Chalamidas Kathrine
- Challappa Krishnan
- Chand Sunil Prakash
- Chandrashekar Harinath
- Chartier Ludovic
- Chatterjee Kausik
- Cheema Aamir
- Cheema Amjad
- Chen Jyh Hong
- Chen Lin
- Chen Shih-Ann
- Chiang Fu-Tien
- Chiarella Francesco
- Chih-Chan Lin
- Cho Yong Keun
- Choi Dong Ju
- Choi Jong-Il
- Chouinard Guy
- Chow Danny Hoi-Fan
- Chreih Rami Mihail
- Chrysos Dimitrios
- Chumakova Galina
- Cislowski David
- Clay Anthony
- Clifford Piers
- Cohen Andrew
- Cohen Michael
- Cohen Serge
- Colivicchi Furio
- Collins Ronan
- Colonna Paolo
- Compton Steve
- Connolly Derek
- Conti Alberto
- Coodley Gregg
- Cooper Martin
- Coronel Julian
- Corso Giovanni
- Cortada Jordi Bruguera
- Cottin Yves
- Covalesky John
- Cracan Aurel
- Crea Filippo
- Crean Peter
- Crenshaw James
- Cullen Tina
- da Costa Darrieux Francisco Carlos
- da Costa Fernando Augusto Alves
- Dahl Jürgen Vom
- Darius Harald
- Dary Patrick
- Dascotte Olivier
- Dauber Ira
- Davalos Vicente
- Davies Ruth
- Davis Gershan
- Davy Jean-Marc
- Dayer Mark
- de Biasio Marzia
- de Bonis Silvana
- de Caterina Raffaele
- de Franceschi Teresiano
- de Groot J.
- de Horta José
- de La Briolle Axel
- de La Pena Topete Gilberto
- de Los Rios Ibarra Manuel Odin
- de Paola Angelo Amato Vicenzo
- de Souza Olga Ferreira
- de Souza Weimar
- de Veer A.
- de Wolf Luc
- Decoulx Eric
- Deepak Sasalu
- Defaye Pascal
- del Río Jorge Eduardo Hernández
- Deumite N. Joseph
- Di Legge Silvia
- Diemberger Igor
- Diener Hans-Christoph
- Dietz Denise
- Dionísio Pedro
- Dong Qiang
- dos Santos Fabio Rossi
- Dotcheva Elena
- Doukky Rami
- Dubner Sergio
- Dubrey Simon
- Ducrocq Xavier
- Dupljakov Dmitry
- Duque Mauricio
- Dutta Dipankar
- Duvilla Nathalie
- Duygun A.
- Dziewas Rainer
- D’souza Anthony
- Eaton Charles
- Eaves William
- Ebels-Tuinbeek L.
- Ehrlich Clifford
- Eichinger-Hasenauer Sabine
- Eisenberg Steven
- Escudero Aldo Edwin Rodriguez
- Esperon Guillermo Llamas
- Esquivias Gonzalo Barón
- Evonich Rudolph
- Evseeva Oksana
- Ezhov Andrey
- Fahmy Raed
- Fang Quan
- Farsad Ramin
- Fauchier Laurent
- Favale Stefano
- Fayard Maxime
- Fedele Francesco
- Fedele Jose Luis
- Fedorishina Olga
- Fera Steven
- Fernández Marcelo Sanmartín
- Ferreira Jorge
- Ferreira Luis Gustavo Gomes
- Ferri Claudio
- Ferrier Anna
- Ferro Hugo
- Filho Adalberto Menezes Lorga
- Filho Dario Sobral
- Finsen Alexandra
- First Brian
- Fischer Stuart
- Fonseca Catarina
- Forman Steven
- Fragoso Juan Carlos Nunez
- Frandsen Brad
- French William
- Friedman Keith
- Friese Athena
- Fruntelata Ana Gabriela
- Fujii Shigeru
- Fumagalli Stefano
- Fundamenski Marta
- Furukawa Yutaka
- Gabelmann Matthias
- Gabra Nashwa
- Gadsbøll Niels
- Galinier Michel
- Gammelgaard Anders
- Ganeshkumar Priya
- Gans Christopher
- Garcéa Jose Polo
- Gartenlaub Olivier
- Gaspardone Achille
- Genz Conrad
- Georger Frédéric
- Georges Jean-Louis
- Georgeson Steven
- Giedrimas Evaldas
- Gierba Mariusz
- Gillespie Eve
- Giniger Alberto
- Giudici Michael
- Gkotsis Alexandros
- Glotzer Taya
- Gmehling Joachim
- Gniot Jacek
- Goethals Peter
- Goldbarg Seth
- Goldberg Ronald
- Goldmann Britta
- Golitsyn Sergey
- Gonzalez Vicente Bertomeu
- González Salvador León
- Gorka Hervé
- Gornick Charles
- Gorog Diana
- Gottipaty Venkat
- Goube Pascal
- Goudevenos Ioannis
- Grado Carlos Antonio Raffo
- Graham Brett
- Greer G. Stephen
- Gremmler Uwe
- Grena Paul
- Grond Martin
- Gronda Edoardo
- Grönefeld Gerian
- Gu Xiang
- Guardigli Gabriele
- Guevara Carolina
- Guignier Alexandre
- Gulizia Michele
- Gumbley Michael
- Gurusamy Venkatesh Kumar
- Gómez Silvia
- Günther Albrecht
- Ha Andrew
- Hahalis Georgios
- Hakas Joseph
- Hall Christian
- Halperin Jonathan
- Han Bing
- Han Seongwook
- Hargrove Joe
- Hargroves David
- Haruna Tetsuya
- Hayek Emil
- Healey Jeff
- Hearne Steven
- Heffernan Michael
- Heggelund Geir
- Heijmeriks J.
- Hemels Maarten
- Hendriks I.
- Henein Sam
- Her Sung-Ho
- Hermany Paul
- Hermosillo Jesus Antonio Gonzalez
- Hernandes Mauro Esteves
- Hernandez Norberto Matadamas
- Higashino Yorihiko
- Hill Michael
- Hisadome Tetsuo
- Hishida Eiji
- Hoffer Etienne
- Hoghton Matthew
- Hong Kui
- Hong Suk Keun
- Horbach Stevie
- Horiuchi Masataka
- Hou Yinglong
- Hsing Jeff
- Huang Chi-Hung
- Huckins David
- Hughes Kathy
- Huisman Menno
- Huizinga A.
- Hulsman E.
- Hung Kuo-Chun
- Hurtado Helard Andres Manrique
- Hwang Gyo-Seung
- Ikpoh Margaret
- Imberti Davide
- Ince Hüseyin
- Indolfi Ciro
- Inoue Shujiro
- Irles Didier
- Iseki Harukazu
- Israel C. Noah
- Iteld Bruce
- Iyer Venkat
- Izal Ana Etxeberria
- Jabali Adnan El
- Jackson-Voyzey Ewart
- Jaffrani Naseem
- James Martin
- Jang Sung-Won
- Jaramillo Nicolas
- Jarmukli Nabil
- Jattin Fernando Manzur
- Jeanfreau Robert
- Jenkins Ronald
- Jimenez Javier
- Jimenez Ricardo Pavón
- Jobe Robert
- Joen-Jakobsen Tomas
- Jones Nicholas
- Jorge Jose Carlos Moura
- Jose Eena Padayattil
- Jouve Bernard
- Jung Byung Chun
- Jung Kyung Tae
- Jung Werner
- Jäger Frank
- Kachkovskiy Mikhail
- Kafkala Krystallenia
- Kalan Marica Bracic
- Kalinina Larisa
- Kallmünzer Bernd
- Kamali Farzan
- Kamo Takehiro
- Kampus Priit
- Kashou Hisham
- Kastrup Andreas
- Katsivas Apostolos
- Kaufman Elizabeth
- Kawai Kazuya
- Kawajiri Kenji
- Kazmierski John
- Keeling P.
- Ketova Galina
- Khaira Ajit Singh
- Khripun Aleksey
- Kim Dae Kyeong
- Kim Doo-Il
- Kim Jeong Su
- Kim Jin Bae
- Kim June Soo
- Kim Ki Seok
- Kim Nam Ho
- Kim Young Hoon
- Kinova Elena
- Klein Alexander
- Kmetzo James
- Kneller G. Larsen
- Knezevic Aleksandar
- Koh Su Mei Angela
- Koide Shunichi
- Kollias Anastasios
- Kooistra J.
- Koons Jay
- Koschutnik Martin
- Kostis William
- Kotalczyk Agnieszka
- Kovacic Dragan
- Kowalczyk Jacek
- Koziolova Natalya
- Kraft Peter
- Kragten Johannes
- Krantz Mori
- Krause Lars
- Krenning B.
- Krikke F.
- Kromhout Z.
- Krysiak Waldemar
- Kumar Priya
- Kuniss Malte
- Kuo Jen-Yuan
- Kurrelmeyer Karla
- Kwak Choong Hwan
- Kümler Thomas
- Küppers Achim
- Laboulle Bénédicte
- Labovitz Arthur
- Lam Andy
- Lam Yat Yin
- Lanas Zanetti Fernando
- Landau Charles
- Landini Giancarlo
- Lanna Figueiredo Estêvão
- Larsen Torben
- Lavandier Karine
- Leblanc Jessica
- Lee Chang-Hoon
- Lee Moon Hyoung
- Lehman John
- Leitão Ana
- Lellouche Nicolas
- Lelonek Malgorzata
- Lenarczyk Radoslaw
- Lenderink T.
- Leong-Sit Peter
- Leschke Matthias
- Ley Nicolas
- Li Weihua
- Li Xiaodong
- Li Xiaoming
- Li Zhanquan
- Lichy Christhoh
- Lieber Ira
- Lin Hailong
- Linares Julio Aguilar
- Lip Gregory
- Liu Feng
- Liu Hengliang
- Lo Eric
- Lokshyn Sergiy
- Lorraine Richard
- Luengas Alberto
- Luengas Carlos Alberto
- Luke Robert
- Luo Ming
- Lupovitch Steven
- Lyrer Philippe
- López Amador
- López Víctor Manuel González
- López-Sendón José Luís
- Ma Chang-Sheng
- Ma Changsheng
- Ma Genshan
- Madariaga Irene
- Maeno Koji
- Magnin Dominique
- Maid Gustavo
- Mainigi Sumeet
- Makaritsis Konstantinos
- Malhotra Rohit
- Manning Rickey
- Manolis Athanasios
- Mantas Ioannis
- Manterola Fernando Alfonso
- Maqueda Vicky
- Marchionni Niccolo
- Marler Sabrina
- Martinez Jorge
- Maskova Petra
- Matsuda Katsuhiro
- Maurer Tillmann
- Mauro Ciro
- May Erik
- Mayer Nolan
- Mazuecos Juan Benezet
- Mcclure John
- Mccormack Terry
- Mcgarity William
- Mcintyre Hugh
- Mclaurin Brent
- Melandri Francesco
- Meno Hiroshi
- Menzies Dhananjai
- Mercader Marco
- Mesa Juan Gomez
- Meyer Beat
- Meyer Christian
- Miarka Jacek
- Mibach Frank
- Michalski Dominik
- Michel Patrik
- Miguel Ricardo Nicolás
- Mikdadi Ghiath
- Mikus Milan
- Milicic Davor
- Militaru Constantin
- Minaie Sedi
- Minescu Bogdan
- Mintale Iveta
- Mirault Tristan
- Mirro Michael
- Mistry Dinesh
- Miu Nicoleta Violeta
- Miyamoto Naomasa
- Miño Mario Vega
- Moccetti Tiziano
- Mohammed Akber
- Mollerus Michael
- Molon Giulio
- Mondillo Sergio
- Moniz Patrícia
- Mont Lluis
- Montagud Vicente
- Montaña Oscar
- Monti Cristina
- Moretti Luciano
- Mori Kiyoo
- Moriarty Andrew
- Morka Jacek
- Moschini Luigi
- Moschos Nikitas
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/05/2022
- Field of study
International audienceIn this article, the name of the GLORIA-AF investigator Anastasios Kollias was given incorrectly as Athanasios Kollias in the Acknowledgements. The original article has been corrected
Patterns of oral anticoagulant use and outcomes in Asian patients with atrial fibrillation: a post-hoc analysis from the GLORIA-AF Registry
- Author
- Abban Dzifa Wosornu
- Abdul Nasser
- Abud Atilio Marcelo
- Adams Fran
- Addala Srinivas
- Adragão Pedro
- Ageno Walter
- Aggarwal Rajesh
- Agosti Sergio
- Agostoni Piergiuseppe
- Aguilar Francisco
- Aguinaga Luis
- Ahmed Jameel
- Aiello Allessandro
- Ainsworth Paul
- Aiub Jorge Roberto
- Al-Dallow Raed
- Alderson Lisa
- Aldrete Velasco Jorge Antonio
- Alexopoulos Dimitrios
- Aliyar Pareed
- Almeida Luísa Fonseca
- Alonso David
- Alves da Costa Fernando Augusto
- Amado José
- Amara Walid
- Amelot Mathieu
- Amjadi Nima
- Ammirati Fabrizio
- Andrade Marianna
- Andrawis Nabil
- Angela Koh Su Mei
- Annoni Giorgio
- Ansalone Gerardo
- Ariani M Kevin
- Arias Juan Carlos
- Armero Sébastien
- Arora Chander
- Asensi Joaquín Osca
- Aslam Muhammad Shakil
- Asselman M
- Audouin Philippe
- Augenbraun Charles
- Aydin S
- Ayryanova Ivaneta
- Aziz Emad
- Backes Luciano Marcelo
- Badings E
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- Shah Neerav
- Shah Shujahat
- Shah Vinay
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- Shaw Louise
- Sheikh Khalid H
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- Shimomura Hideki
- Shin Dong-Gu
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- Simmers Tim A
- Singh Takhar Amrit Pal
- Singh Narendra
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- Smadja Didier
- Smith David W
- Snitman Marcelo
- Soda Hassan
- Sofley Carl
- Sokal Adam
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- Sparby Jon Arne
- Spinar Jindrich
- Sprigings David
- Spyropoulos Alex C
- Stakos Dimitrios
- Steinwender Clemens
- Stergiou Georgios
- Stiell Ian
- Stoddard Marcus
- Stoikov Anastas
- Streb Witold
- Styliadis Ioannis
- Su Guohai
- Su Xi
- Sudnik Wanda
- Sukles Kai
- Sun Xiaofei
- Swart H
- Szavits-Nossan Janko
- Sánchez Carlos Jerjes
- Sánchez Mauricio Camarillo
- Taggeselle Jens
- Takagi Yuichiro
- Tamm Angelika
- Tanaka Katsumi
- Tanawuttiwat Tanyanan
- Tang Aylmer
- Tang Sherman
- Tarsi Giovanni
- Tassinari Tiziana
- Tayal Ashis
- Tayebjee Muzahir
- Tesloianu Dan
- The Salem HK
- Thomas Dierk
- Timsit Serge
- Tobaru Tetsuya
- Tomasik Andrzej R
- Topete Gilberto de la Pena
- Torosoff Mikhail
- Torres Torres Ivett Guadalupe
- Touze Emmanuel
- Trendafilova Elina
- Tsai W Kevin
- Tse Hung Fat
- Tsutsui Hiroshi
- Tu Tian Ming
- Tuininga Ype
- Turakhia Minang
- Turk Samir
- Turner Wayne
- Tveit Arnljot
- Tytus Richard
- Valadão C
- Valenzuela Chuquiure
- Vallejo Gregorio Sanchez
- van Bergen PFMM
- van de Borne Philippe
- van den Berg BJ
- van der Zwaan C
- Van Eck M
- Vanacker Peter
- Vasilev Dimo
- Vasilikos Vasileios
- Vasilyev Maxim
- Veerareddy Srikar
- Vera Tomas Ripolil
- Verdecchia Paolo
- Versaci Francesco
- Vester Ernst Günter
- Vial Hubert
- Vicenzo de Paola Angelo Amato
- Victory Jason
- Villamil Alejandro
- Vincent Marc
- Vlastaris Anthony
- Vora Kishor
- Vranian Robert B
- Wakefield Paul
- Wang Feng
- Wang Mingsheng
- Wang Ningfu
- Wang Tian
- Wang Xinhua
- Warner Alberta L
- Watanabe Kouki
- Wei Jeanne
- Weimar Christian
- Weiner Stanislav
- Weinrich Renate
- Wen Ming-Shien
- Wiemer Marcus
- Wiggers Preben
- Wilke Andreas
- Williams David
- Williams Marcus L
- Witzenbichler Bernhard
- Wong Brian
- Wozakowska-Kaplon Beata
- Wu Richard C
- Wu Shulin
- Wunderlich Silke
- Wyatt Nell
- Wylie John Jack
- Xu Xiangdong
- Xu Yong
- Yamanoue Hiroki
- Yamashita Takeshi
- Yang Tianlun
- Yao Jing
- Yeh Kuo-Ho
- Yin Wei Hsian
- Yotov Yoto
- Zahn Ralf
- Zanetti Fernando Lanas
- Zarich Stuart
- Zenin Sergei
- Zeuthen Elisabeth Louise
- Zhang Donghui
- Zhang Huanyi
- Zhang Jun
- Zhang Ping
- Zhang Xingwei
- Zhao Shui Ping
- Zhao Yujie
- Zhao Zhichen
- Zheng Yang
- Zhou Jing
- Zimmermann Sergio
- Zini Andrea
- Zizzo Steven
- Zong Wenxia
- Zukerman L Steven
- Publication venue
- Elsevier BV
- Publication date
- 01/01/2023
- Field of study
Background: Previous studies suggested potential ethnic differences in the management and outcomes of atrial fibrillation (AF). We aim to analyse oral anticoagulant (OAC) prescription, discontinuation, and risk of adverse outcomes in Asian patients with AF, using data from a global prospective cohort study. Methods: From the GLORIA-AF Registry Phase II-III (November 2011-December 2014 for Phase II, and January 2014-December 2016 for Phase III), we analysed patients according to their self-reported ethnicity (Asian vs. non-Asian), as well as according to Asian subgroups (Chinese, Japanese, Korean and other Asian). Logistic regression was used to analyse OAC prescription, while the risk of OAC discontinuation and adverse outcomes were analysed through Cox-regression model. Our primary outcome was the composite of all-cause death and major adverse cardiovascular events (MACE). The original studies were registered with ClinicalTrials.gov, NCT01468701, NCT01671007, and NCT01937377. Findings: 34,421 patients were included (70.0 ± 10.5 years, 45.1% females, 6900 (20.0%) Asian: 3829 (55.5%) Chinese, 814 (11.8%) Japanese, 1964 (28.5%) Korean and 293 (4.2%) other Asian). Most of the Asian patients were recruited in Asia (n = 6701, 97.1%), while non-Asian patients were mainly recruited in Europe (n = 15,449, 56.1%) and North America (n = 8378, 30.4%). Compared to non-Asian individuals, prescription of OAC and non-vitamin K antagonist oral anticoagulant (NOAC) was lower in Asian patients (Odds Ratio [OR] and 95% Confidence Intervals (CI): 0.23 [0.22-0.25] and 0.66 [0.61-0.71], respectively), but higher in the Japanese subgroup. Asian ethnicity was also associated with higher risk of OAC discontinuation (Hazard Ratio [HR] and [95% CI]: 1.79 [1.67-1.92]), and lower risk of the primary composite outcome (HR [95% CI]: 0.86 [0.76-0.96]). Among the exploratory secondary outcomes, Asian ethnicity was associated with higher risks of thromboembolism and intracranial haemorrhage, and lower risk of major bleeding. Interpretation: Our results showed that Asian patients with AF showed suboptimal thromboembolic risk management and a specific risk profile of adverse outcomes; these differences may also reflect differences in country-specific factors. Ensuring integrated and appropriate treatment of these patients is crucial to improve their prognosis. Funding: The GLORIA-AF Registry was funded by Boehringer Ingelheim GmbH
The Changing Landscape for Stroke Prevention in AF
- Author
- A. Elvan
- A. Huizenga
- A. Shekhar Pandey
- Aamir Cheema
- Abayomi Osunkoya
- Abdel El Hallak
- Abdelfatah Alasfar
- Abdul Alawwa
- Abdullah Ali
- Abraham Salacata
- Abul Azim
- Achim Küppers
- Adalberto Menezes Lorga Filho
- Adam Ellery
- Adam Sokal
- Adnan El Jabali
- Adrien Salem
- Ajit Khaira
- Akber Mohammed
- Akira Yamada
- Alain Lacroix
- Alan Ackermann
- Alan Bank
- Alan Bell
- Alberto Caccavo
- Alberto Conti
- Alberto Giniger
- Aleksandar Knezevic
- Aleksey Khripun
- Alenka Mavri
- Alessandro Capucci
- Alessandro Salvioni
- Alex Spyropoulos
- Alexander Klein
- Alexander Paraschos
- Alexandra Finsen
- Alexandre Guignier
- Alexandros Gkotsis
- Alexey Nizov
- Alfredo Astesiano
- Ali Ghanbasha
- Ali Sharareh
- Alon Steinberg
- Alvaro Rabelo Alves
- Aman Shah
- Ameer Kabour
- Amelie Elsaesser
- Amin Karim
- Amir Malik
- Amparo Mena
- Amrit Takhar
- Ana Gabriela Fruntelata
- Ana Leitão
- Anastas Stoikov
- Andrea Berz
- Andreas Götte
- Andreas Kastrup
- Andreas Meinel
- Andreas Mügge
- Andreas Wilke
- Andreas Winkler
- Andrew Cohen
- Andrew Moriarty
- Andrew Rubin
- Andrey Ezhov
- Andy Lam
- Angel Grande
- Angel Moya
- Angelika Tamm
- Angelo Amato Vicenzo de Paola
- Anil Shah
- Anna Ferrier
- Anthony Clay
- Anthony D'Souza
- Anthony Vlastaris
- Antonio Garcia Quintana
- Antonio Martín Santana
- Antonio Pose
- Antonius Ziekenhuis
- Apostolos Katsivas
- Armando Pineda-Velez
- Arnljot Tveit
- Arnold Pinter
- Arthur Labovitz
- Arturo Raisaro
- Asaad Bakbak
- Asok Venkataraman
- Athanasios Manolis
- Athanasios Pras
- Atsushi Sueyoshi
- Attilia Maria Pizzini
- Aurel Cracan
- Aurélie Buhl
- Aurélien Miralles
- Axel Brandes
- Axel De La Briolle
- Ayham Al-Zoebi
- Aylmer Tang
- Azlisham Mohd Nor
- B.J. Berg van den
- B.J. Krenning
- Barry Seidman
- Barry Troyan
- Basel Hanbali
- Beat Meyer
- Beata Wozakowska-Kaplon
- Beate Wild
- Begoña Sevilla
- Bengt Johansson
- Benhur Henz
- Benoit Coutu
- Benoit Lequeux
- Benzy Padanilam
- Bernard Erickson
- Bernard Jouve
- Bernhard Witzenbichler
- Bernhard-Paul Lodde
- Bettina Schmitz
- Bhola Rama
- Bjørn Bratland
- Bogdan Minescu
- Bouziane Benhalima
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- Brent McLaurin
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- C. Zwaan van der
- Camm
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- Carisi Anne Polanczyk
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- Changsheng Ma
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- Chi-Hung Huang
- Chia Theng Daniel Oh
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- Granger
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- Huisman
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