The interpretation of TIROS radiation data for practical use in synoptic weather analysis

Interpretation of TIROS III radiation data to demonstrate practical applications in synoptic weather analyse

Characterisation of a Coriolis flow meter for fuel consumption measurements in realistic drive cycle tests

When testing light-duty and heavy-duty vehicles on chassis dynamometers, as in the WLTP, or engines on engine test benches, as in the WHDC, it is required to measure the fuel consumption. In the preferable case, the measurement of the fuel consumption is carried out with suitable flow meters. These require high measurement accuracy in a wide flow range, independent of the fuel type, as the flow rate range is often very large and depends on the power range of the vehicle engines. Moreover, the fuel flow rate in the test cycles is very dynamically related to the loads. In the scope of the ongoing EMPIR Joint Research Project 20IND13 SAFEST the dynamic flow behaviour as well as the measurement accuracy of flow meters for different types of fuels are investigated. This paper presents first results from the realisation of dynamic flow profiles, and flow measurements with a Coriolis Flow Meter with different representative fuels in a wide density and viscosity range and a wide flow rate range at different fuel temperatures

Turbulent dynamo with advective magnetic helicity flux

Many astrophysical bodies harbor magnetic fields that are thought to be sustained by a dynamo process. However, it has been argued that the production of large-scale magnetic fields by mean-field dynamo action is strongly suppressed at large magnetic Reynolds numbers owing to the conservation of magnetic helicity. This phenomenon is known as {\it catastrophic quenching}. Advection of magnetic fields by stellar and galactic winds toward the outer boundaries and away from the dynamo is expected to alleviate such quenching. Here we explore the relative roles played by advective and turbulent--diffusive fluxes of magnetic helicity in the dynamo. In particular, we study how the dynamo is affected by advection. We do this by performing direct numerical simulations of a turbulent dynamo of $\alpha^2$ type driven by forced turbulence in a Cartesian domain in the presence of a flow away from the equator where helicity changes sign. Our results indicate that in the presence of advection, the dynamo, otherwise stationary, becomes oscillatory. We confirm an earlier result for turbulent--diffusive magnetic helicity fluxes that for small magnetic Reynolds numbers (\Rm\lesssim 100...200, based on the wavenumber of the energy-carrying eddies) the magnetic helicity flux scales less strongly with magnetic Reynolds number (\Rm^{-1/2}) than the term describing magnetic helicity destruction by resistivity (\Rm^{-1}). Our new results now suggest that for larger \Rm the former becomes approximately independent of \Rm, while the latter falls off more slowly. We show for the first time that both for weak and stronger winds, the magnetic helicity flux term becomes comparable to the resistive term for \Rm\gtrsim 1000, which is necessary for alleviating catastrophic quenching.Comment: 9 pages, 9 figures, accepted for publication in MNRA

Sterol 3β-glucosyltransferase biocatalysts with a range of selectivities, including selectivity for testosterone

The main objectives of this work were to characterise a range of purified recombinant sterol 3β-glucosyltransferases and show that rational sampling of the diversity that exists within sterol 3β-glucosyltransferase sequence space can result in a range of enzyme selectivities. In our study the catalytically active domain of the Saccharomyces cerevisiae 3β-glucosyltransferase was used to mine putative sterol 3β-glucosyltransferases from the databases. Selected diverse sequences were expressed in and purified from Escherichia coli and shown to have different selectivities for the 3β-hydroxysteroids ergosterol and cholesterol. Surprisingly, three enzymes were also selective for testosterone, a 17β-hydroxysteroid. This study therefore reports for the first time sterol 3β-glucosyltransferases with selectivity for both 3β- and 17β-hydroxysteroids and is also the first report of recombinant 3β-glucosyltransferases with selectivity for steroids with a hydroxyl group at positions other than C-3. These enzymes could therefore find utility in the pharmaceutical industry for the green synthesis of a range of glycosylated compounds of medicinal interest

Torpor in marsupials: Recent advances

We report new findings about torpor in marsupials with regard to three energy demanding processes: (i) development and growth, (ii) reproduction, and (iii) rewarming. Young marsupials use torpor extensively after they develop endothermy, and torpor is generally deeper and longer than in the same individuals when they reach adult size. Adult marsupials also employ torpor during pregnancy and/or lactation to reduce energy expenditure and perhaps to store fat for later use. Moreover, to enhance the energy-conserving potential of torpor, desert marsupials bask during arousal to minimize energy costs of rewarming. We show that the functions of torpor extend beyond merely reducing energy expenditure during food shortages and that torpor can save substantial amounts of energy even during the rewarming process

Solidification of small para-H2 clusters at zero temperature

We have determined the ground-state energies of para-H$_2$ clusters at zero temperature using the diffusion Monte Carlo method. The liquid or solid character of each cluster is investigated by restricting the phase through the use of proper importance sampling. Our results show inhomogeneous crystallization of clusters, with alternating behavior between liquid and solid phases up to N=55. From there on, all clusters are solid. The ground-state energies in the range N=13--75 are established and the stable phase of each cluster is determined. In spite of the small differences observed between the energy of liquid and solid clusters, the corresponding density profiles are significantly different, feature that can help to solve ambiguities in the determination of the specific phase of H$_2$ clusters.Comment: 17 pages, accepted for publication in J. Phys. Chem.

Simulations of Solar and Stellar Dynamos and Their Theoretical Interpretation

This is the final version. Available on open access from Springer via the DOI in this recordWe review the state of the art of three dimensional numerical simulations of solar and stellar dynamos. We summarize fundamental constraints of numerical modelling and the techniques to alleviate these restrictions. Brief summary of the relevant observations that the simulations seek to capture is given. We survey the current progress of simulations of solar convection and the resulting large-scale dynamo. We continue to studies that model the Sun at different ages and to studies of stars of different masses and evolutionary stages. Both simulations and observations indicate that rotation, measured by the Rossby number which is the ratio of rotation period and convective turnover time, is a key ingredient in setting the overall level and characteristics of magnetic activity. Finally, efforts to understand global 3D simulations in terms of mean-field dynamo theory are discussed.Deutsche Forschungsgemeinschaft (DFG)European Union Horizon 2020European Research Council (ERC)CNRS/INSUCNESObservatory OSUPSUniversité Paris-SaclayUniversité Paris CitéScience and Technology Facilities Council (STFC)NAS

Does negative auto-regulation increase gene duplicability?

BACKGROUND: A prerequisite for a duplication to spread through and persist in a given population is retaining expression of both gene copies. Yet changing a gene's dosage is frequently detrimental to fitness. Consequently, dosage-sensitive genes are less likely to duplicate. However, in cases where the level of gene product is controlled, via negative feedback, by its own abundance, an increase in gene copy number can in principle be decoupled from an increase in protein while both copies remain expressed. Using data from the transcriptional networks of E. coli and S. cerevisiae, we test the hypothesis that genes under negative auto-regulation show enhanced duplicability. RESULTS: Controlling for several known correlates of duplicability, we find no statistically significant support in either E. coli or S. cerevisiae that transcription factors under negative auto-regulation hold a duplicability advantage over transcription factors with no auto-regulation. CONCLUSION: Based on the analysis of transcriptional networks in E. coli and S. cerevisiae, there is no evidence that negative auto-regulation has contributed, on a genome-wide scale, to the variability in gene family sizes in these species