Moving from Class to Chambers: Five Tips for Training New Clerks to Write for You

For eleven years, I have taught new legal writers. I primarily teach UNC Law’s 1L research, writing, and advocacy class, but in recent years have also taught an upper-level seminar titled Judicial Clerkship Writing for those students interested in learning to write like a clerk. The students in both classes differ in skill level, naturally, but they have in common that they have never before done the type of writing the class requires of them. Judges do much the same. Each time a new clerk or intern joins your chambers, you start training and guiding anew. Below are five increasingly specific tips on how to make that process as smooth as possible

Maria Auxiliadora Hospital in Lima, Peru as a model for neurosurgical outreach to international charity hospitals

A myriad of geopolitical and financial obstacles have kept modern neurosurgery from effectively reaching the citizens of the developing world. Targeted neurosurgical outreach by academic neurosurgeons to equip neurosurgical operating theaters and train local neurosurgeons is one method to efficiently and cost effectively improve sustainable care provided by international charity hospitals. The International Neurosurgical Children’s Association (INCA) effectively improved the available neurosurgical care in the Maria Auxiliadora Hospital of Lima, Peru through the advancement of local specialist education and training. Neurosurgical equipment and training were provided for the local neurosurgeons by a mission team from the University of California at San Diego. At the end of 3 years, with one intensive week trip per year, the host neurosurgeons were proficiently and independently applying microsurgical techniques to previously performed operations, and performing newly learned operations such as neuroendoscopy and minimally invasive neurosurgery. Our experiences may serve as a successful template for the execution of other small scale, sustainable neurosurgery missions worldwide

A methodological quest for systematic literature mapping

This article develops an approach to systematic literature mapping that can contribute to advancing housing knowledge and theory in three ways. At a basic level, it informs more systematic, balanced and transparent literature reviews than currently performed in housing studies. As a self-contained project, it unravels research gaps, highlights where rich evidence already exists, and indicates changing conceptual approaches. Lastly, as an opening stage to evidence reviews, it informs the review’s questions, directions and dimensions. Our approach to literature mapping systematically identifies and explores a comprehensive but non-exhaustive literature related to a broad academic or policy theme. We have adapted established methodological approaches from systematic reviews to our much broader aims and shorter timeframe. By reflecting on five projects, we detail the methodological process so that it could be replicated or adapted in future studies. Besides reflecting on the systematic and less biased retrieval of relevant literature―pertinent to any academic project―we present insights into synthesising its temporal, geographical, conceptual and thematic trends. We also reflect on some inevitable methodological challenges faced in this process of translation of aims into the narration of findings, which have a wider currency across the social sciences

School toilets : queer, disabled bodies and gendered lessons of embodiment

In this paper we argue that school toilets function as one civilising site (Elias, 1978) in which children learn that disabled and queer bodies are out of place. This paper is the first to offer queer and crip perspectives on school toilets. The small body of existing school toilet literature generally works from a normative position which implicitly perpetuates dominant and oppressive ideals. We draw on data from Around the Toilet, a collaborative research project with queer, trans and disabled people (aroundthetoilet.wordpress.com) to critically interrogate this work. In doing this we consider ‘toilet training’ as a form of ‘civilisation’, that teaches lessons around identity, embodiment and ab/normal ways of being in the world. Furthermore, we show that ‘toilet training’ continues into adulthood, albeit in ways that are less easily identifiable than in the early years. We therefore call for a more critical, inclusive, and transformative approach to school toilet research

To investigate relative effectiveness of the dimensions of interactivity

This thesis is about interactivity. It is about the dimensions of interactive communication which have become a major element of contemporary marketing practice. The concept of interactivity has been explored in the fields of advertising research, and communication and media studies. However, there is an overall absence of any published work concerning research into the dimensions of interactivity, in the marketing domain. This thesis seeks to correct this situation and investigates the relative effectiveness of the dimensions of interactivity, set in the context of travel weblogs. The aim is to determine how three principal dimensions of interactivity namely, active control, two-way communication, and real-time communication, affects users‟ attitudes and usage intentions. This thesis also examines the effect of motive factors, such as social interaction, information of travel weblogs, and enjoyment, upon a user‟s attitudes and usage intentions. The relationships among these variables are examined within a research framework provided by this study. Data was collected through an online questionnaire and semi-structured interviews. The findings verify that the dimensions of interactivity and motivation factors can have positive influence upon users‟ attitudes and usage intentions.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Approaches to link RNA secondary structures with splicing regulation

In higher eukaryotes, alternative splicing is usually regulated by protein factors, which bind to the pre-mRNA and affect the recognition of splicing signals. There is recent evidence that the secondary structure of the pre-mRNA may also play an important role in this process, either by facilitating or by hindering the interaction with factors and small nuclear ribonucleoproteins (snRNPs) that regulate splicing. Moreover, the secondary structure could play a fundamental role in the splicing of yeast species, which lack many of the regulatory splicing factors present in metazoans. This review describes the steps in the analysis of the secondary structure of the pre-mRNA and its possible relation to splicing. As a working example, we use the case of yeast and the problem of the recognition of the 3-prime splice site.Comment: 21 pages, 7 figure

GC content around splice sites affects splicing through pre-mRNA secondary structures

<p>Abstract</p> <p>Background</p> <p>Alternative splicing increases protein diversity by generating multiple transcript isoforms from a single gene through different combinations of exons or through different selections of splice sites. It has been reported that RNA secondary structures are involved in alternative splicing. Here we perform a genomic study of RNA secondary structures around splice sites in humans (<it>Homo sapiens</it>), mice (<it>Mus musculus</it>), fruit flies (<it>Drosophila melanogaster</it>), and nematodes (<it>Caenorhabditis elegans</it>) to further investigate this phenomenon.</p> <p>Results</p> <p>We observe that GC content around splice sites is closely associated with the splice site usage in multiple species. RNA secondary structure is the possible explanation, because the structural stability difference among alternative splice sites, constitutive splice sites, and skipped splice sites can be explained by the GC content difference. Alternative splice sites tend to be GC-enriched and exhibit more stable RNA secondary structures in all of the considered species. In humans and mice, splice sites of first exons and long exons tend to be GC-enriched and hence form more stable structures, indicating the special role of RNA secondary structures in promoter proximal splicing events and the splicing of long exons. In addition, GC-enriched exon-intron junctions tend to be overrepresented in tissue-specific alternative splice sites, indicating the functional consequence of the GC effect. Compared with regions far from splice sites and decoy splice sites, real splice sites are GC-enriched. We also found that the GC-content effect is much stronger than the nucleotide-order effect to form stable secondary structures.</p> <p>Conclusion</p> <p>All of these results indicate that GC content is related to splice site usage and it may mediate the splicing process through RNA secondary structures.</p