Chlamydia diagnosis rate in England in 2012: an ecological study of local authorities

Objectives Local authorities (LAs) in England commission chlamydia screening as part of the National Chlamydia Screening Programme. It is recommended that LAs achieve a chlamydia diagnosis rate of ≥2300 cases per 100 000 population aged 15–24. We describe national patterns in attainment of the chlamydia diagnosis rate recommendation and possible implications of using it to measure LA-level performance. Methods We used publicly available data sets from England (2012) to explore the association between LAs attaining the recommended chlamydia diagnosis rate and population size, socioeconomic deprivation, test setting and sex. Results We used data from 1 197 121 recorded chlamydia tests in females and 564 117 in males. The chlamydia diagnosis rate recommendation was achieved by 22% (72/324) of LAs overall (43% female population; 8% male population). LAs in the highest deprivation quintile were more likely to reach the recommendation than those in the least-deprived quintile for both sexes (women: unadjusted prevalence ratio (UPR) 7.43, 95% CI 3.65 to 15.11; men: UPR 7.00, 95% CI 1.66 to 29.58). The proportion of tests performed in genitourinary medicine clinics was negatively associated with attainment of the recommended diagnosis rate (UPR 0.95, 0.93 to 0.97). Conclusions Chlamydia diagnosis rate recommendations that reflect local area deprivation (as a proxy for disease burden) may be more appropriate than a single national target if the aim is to reduce health inequalities nationally. We suggest LAs monitor their chlamydia diagnosis rate, test coverage and test positivity across a range of measures (including setting and sex) and pre/post changes to commissioned services. Critical evaluation of performance against the recommendation should be reflected in local commissioning decisions

Discharge chamber studies for mercury bombardment ion thrusters

Discharge chamber performance optimization for mercury bombardment ion thruster

The Taurus Boundary of Stellar/Substellar (TBOSS) Survey I: far-IR disk emission measured with Herschel

With Herschel/PACS 134 low mass members of the Taurus star-forming region spanning the M4-L0 spectral type range and covering the transition from low mass stars to brown dwarfs were observed. Combining the new Herschel results with other programs, a total of 150 of the 154 M4-L0 Taurus members members have observations with Herschel. Among the 150 targets, 70um flux densities were measured for 7 of the 7 ClassI objects, 48 of the 67 ClassII members, and 3 of the 76 ClassIII targets. For the detected ClassII objects, the median 70um flux density level declines with spectral type, however, the distribution of excess relative to central object flux density does not change across the stellar/substellar boundary in the M4-L0 range. Connecting the 70um TBOSS values with the results from K0-M3 ClassII members results in the first comprehensive census of far-IR emission across the full mass spectrum of the stellar and substellar population of a star-forming region, and the median flux density declines with spectral type in a trend analogous to the flux density decline expected for the central objects. SEDs were constructed for all TBOSS targets covering the optical to far-IR range and extending to the submm/mm for a subset of sources. Based on an initial exploration of the impact of different physical parameters; inclination, scale height and flaring have the largest influence on the PACS flux densities. From the 24um to 70um spectral index of the SEDs, 5 new candidate transition disks were identified. The steep 24um to 70um slope for a subset of 8 TBOSS targets may be an indication of truncated disks in these systems.Two examples of mixed pair systems that include secondaries with disks were measured. Finally, comparing the TBOSS results with a Herschel study of Ophiuchus brown dwarfs reveals a lower fraction of disks around the Taurus substellar population.Comment: 64 pages, 33 figures, 12 tables, accepted for publication in A&

Optical Subcarrier Communications

This paper discusses the use of rf subcarriers placed on optical beams for communication purposes. Through the use of advanced optical beam processing and post detection electronic processing, the advantages of optical frequency techniques can be combined with the mature background of the rf technology. These techniques are expected to find applications for long range wideband communication, spacecraft tracking and rendezvous, and altimetry, as well as for aircraft and spacecraft landing aids

A new method for monitoring global volcanic activity

The ERTS Data Collection System makes it feasible for the first time to monitor the level of activity at widely separated volcanoes and to relay these data rapidly to one central office for analysis. While prediction of specific eruptions is still an evasive goal, early warning of a reawakening of quiescent volcanoes is now a distinct possibility. A prototypical global volcano surveillance system was established under the ERTS program. Instruments were installed in cooperation with local scientists on 15 volcanoes in Alaska, Hawaii, Washington, California, Iceland, Guatemala, El Salvador and Nicaragua. The sensors include 19 seismic event counters that count four different sizes of earthquakes and six biaxial borehole tiltmeters that measure ground tilt with a resolution of 1 microradian. Only seismic and tilt data are collected because these have been shown in the past to indicate most reliably the level of volcano activity at many different volcanoes. Furthermore, these parameters can be measured relatively easily with new instrumentation

Recent applications of NMR spectroscopy in plant metabolomics

Recent research has established NMR as a key method for high-throughput comparative analysis of plant extracts. We discuss recent examples of the use of NMR to provide metabolomic data for various applications in plant science and look forward to the key role that NMR will play in data provision for plant systems biology