1,102 research outputs found
A Co(TAML)-based artificial metalloenzyme for asymmetric radical-type oxygen atom transfer catalysis
We show that the incorporation of a biotinylated Co(TAML) cofactor within streptavidin enables asymmetric radical-type oxygen atom transfer catalysis with improved activity and enantioselectivity.</p
String Necklaces and Primordial Black Holes from Type IIB Strings
We consider a model of static cosmic string loops in type IIB string theory,
where the strings wrap cycles within the internal space. The strings are not
topologically stabilised, however the presence of a lifting potential traps the
windings giving rise to kinky cycloops. We find that PBH formation occurs at
early times in a small window, whilst at late times we observe the formation of
dark matter relics in the scaling regime. This is in stark contrast to previous
predictions based on field theoretic models. We also consider the PBH
contribution to the mass density of the universe, and use the experimental data
to impose bounds on the string theory parameters.Comment: 45 pages, 9 figures, LaTeX; published versio
Non-Abelian (p,q) Strings in the Warped Deformed Conifold
We calculate the tension of -strings in the warped deformed conifold
using the non-Abelian DBI action. In the large flux limit, we find exact
agreement with the recent expression obtained by Firouzjahi, Leblond and
Henry-Tye up to and including order terms if is also taken to be
large. Furthermore using the finite prescription for the symmetrised trace
operation we anticipate the most general expression for the tension valid for
any . We find that even in this instance, corrections to the tension
scale as which is not consistent with simple Casimir scaling.Comment: 18 pages, Latex, 1 figure; Added a discussion of the case when the
warp factor parameter and typos correcte
Association of MRI T1 relaxation time with neuropsychological test performance in manganese- exposed welders
This study examines the results of neuropsychological testing of 26 active welders and 17 similar controls and their relationship to welders' shortened MRI T1 relaxation time, indicative of increased brain manganese (Mn) accumulation. Welders were exposed to Mn for an average duration of 12.25 years to average levels of Mn in air of 0.11±0.05mg/m3. Welders scored significantly worse than controls on Fruit Naming and the Parallel Lines test of graphomotor tremor. Welders had shorter MRI T1 relaxation times than controls in the globus pallidus, substantia nigra, caudate nucleus, and the anterior prefrontal lobe. 63% of the variation in MRI T1 relaxation times was accounted for by exposure group. In welders, lower relaxation times in the caudate nucleus and substantia nigra were associated with lower neuropsychological test performance on tests of verbal fluency (Fruit Naming), verbal learning, memory, and perseveration (WHO-UCLA AVLT). Results indicate that verbal function may be one of the first cognitive domains affected by brain Mn deposition in welders as reflected by MRI T1 relaxation times
Polarization coupling and pattern selection in a type-II optical parametric oscillator
We study the role of a direct intracavity polarization coupling in the
dynamics of transverse pattern formation in type-II optical parametric
oscillators. Transverse intensity patterns are predicted from a stability
analysis, numerically observed, and described in terms of amplitude equations.
Standing wave intensity patterns for the two polarization components of the
field arise from the nonlinear competition between two concentric rings of
unstable modes in the far field. Close to threshold a wavelength is selected
leading to standing waves with the same wavelength for the two polarization
components. Far from threshold the competition stabilizes patterns in which two
different wavelengths coexist.Comment: 14 figure
Electrified Fuzzy Spheres and Funnels in Curved Backgrounds
We use the non-Abelian DBI action to study the dynamics of coincident
-branes in an arbitrary curved background, with the presence of a
homogenous world-volume electric field. The solutions are natural extensions of
those without electric fields, and imply that the spheres will collapse toward
zero size. We then go on to consider the intersection in a curved
background and find various dualities and automorphisms of the general
equations of motion. It is possible to map the dynamical equation of motion to
the static one via Wick rotation, however the additional spatial dependence of
the metric prevents this mapping from being invertible. Instead we find that a
double Wick rotation leaves the static equation invariant. This is very
different from the behaviour in Minkowski space. We go on to construct the most
general static fuzzy funnel solutions for an arbitrary metric either by solving
the static equations of motion, or by finding configurations which minimise the
energy. As a consistency check we construct the Abelian -brane world-volume
theory in the same generic background and find solutions consistent with energy
minimisation. In the 5-brane background we find time dependent solutions to
the equations of motion, representing a time dependent fuzzy funnel. These
solutions match those obtained from the -string picture to leading order
suggesting that the action in the large limit does not need corrections. We
conclude by generalising our solutions to higher dimensional fuzzy funnels.Comment: 38 pages, Latex; references adde
Managing groundwater supplies subject to drought: perspectives on current status and future priorities from England (UK)
Effective management of groundwater resources during drought is essential. How is groundwater currently managed during droughts, and in the face of environmental change, what should be the future priorities? Four themes are explored, from the perspective of groundwater management in England (UK): (1) integration of drought definitions; (2) enhanced fundamental monitoring; (3) integrated modelling of groundwater in the water cycle; and (4) better information sharing. Whilst these themes are considered in the context of England, globally, they are relevant wherever groundwater is affected by drought
X-wave mediated instability of plane waves in Kerr media
Plane waves in Kerr media spontaneously generate paraxial X-waves (i.e.
non-dispersive and non-diffractive pulsed beams) that get amplified along
propagation. This effect can be considered a form of conical emission (i.e.
spatio-temporal modulational instability), and can be used as a key for the
interpretation of the out of axis energy emission in the splitting process of
focused pulses in normally dispersive materials. A new class of spatio-temporal
localized wave patterns is identified. X-waves instability, and nonlinear
X-waves, are also expected in periodical Bose condensed gases.Comment: 4 pages, 6 figure
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