On Béziau’s logic Z

In [1] Béziau developed the paraconsistent logic Z, which is definitionally equivalent to the modal logic S5 (cf. Remark 2.3), and gave an axiomatization of the logic Z: the system HZ. In the present paper, we prove that some axioms of HZ are not independent and then propose another axiomatization of Z. We also discuss a new perspective on the relation between S5 and classical propositional logic (CPL) with the help of the new axiomatization of Z. Then we conclude the paper by making a remark on the paraconsistency of HZ

Some new results on PCL1 and its related systems

In [Waragai & Shidori, 2007], a system of paraconsistent logic called PCL1, which takes a similar approach to that of da Costa, is proposed. The present paper gives further results on this system and its related systems. Those results include the concrete condition to enrich the system PCL1 with the classical negation, a comparison of the concrete notion of “behaving classically” given by da Costa and by Waragai and Shidori, and a characterisation of the notion of “behaving classically” given by Waragai and Shidori

The Function of Religious Language in the Media: A Comparative Analysis of the Japanese, German and American Newspaper Coverage about the 2011 Great East Japan Earthquake and Tsunami

When an incident or event in a certain region will be reported by the mass media in a different language, the choice of expressions, the perspective and aim of their message will differ. This study analyzes the news coverage of events related to the 2011 Great East Japan Earthquake and Tsunami in German, American and Japanese newspapers. It will aim to uncover expressional differences in the coverage on a similar topic reported in different languages. This research especially focuses on the use of religious language in the coverage, which in this paper refers to religious metaphors and symbols originating from a Christian context. Previous research shows that the use of religious language in the media, affects consumers mentally and emotionally. Based on that theory, this study compares how religious language is used in the coverage and tries to clarify the functions of religious expressions through a critical discourse analysis. The results show that religious language appears continuously in German and American news reports related to the disaster. Religious language is mostly used symbolically as well as metaphorically in order to illustrate the destruction caused by the earthquake, tsunami and nuclear disaster, while at the same time conveying emotions such as the fear of the victims. It is also used to describe the difficulties, suffering and hope of the people in the disaster-hit area. Moreover religious language provokes emotions in the readers and makes it easier for them to understand the situation in Japan as well as the feelings of the disaster refugees.  A difference between the German and American news coverage was seen in the description of the situation at the nuclear power plant and the state of the victims in Fukushima and the Tohoku region. In Germany, religious language can change the viewpoint of and provoke emotions in the readers. It is also employed to emphasize domestic social and political problems related to German energy policy

Bridging Molecular Genetics and Biomarkers in Lewy Body and Related Disorders

Recent advances have been made in defining the genetic and molecular basis of dementia with Lewy bodies (DLBs) and related neurodegenerative disorders such as Parkinson's disease (PD) and Parkinson's disease dementia (PDD) which comprise the spectrum of “Lewy body disorders” (LBDs). The genetic alterations and underlying disease mechanisms in the LBD overlap substantially, suggesting common disease mechanisms. As with the other neurodegenerative dementias, early diagnosis in LBD or even identification prior to symptom onset is key to developing effective therapeutic strategies, but this is dependent upon the development of robust, specific, and sensitive biomarkers as diagnostic tools and therapeutic endpoints. Recently identified mutations in the synucleins and other relevant genes in PD and DLB as well as related biomolecular pathways suggest candidate markers from biological fluids and imaging modalities that reflect the underlying disease mechanisms. In this context, several promising biomarkers for the LBD have already been identified and examined, while other intriguing possible candidates have recently emerged. Challenges remain in defining their correlation with pathological processes and their ability to detect DLB and related disorders, and perhaps a combined array of biomarkers may be needed to distinguish various LBDs

Clinical significance of serum Wisteria floribunda agglutinin-positive Mac-2 binding protein in pancreatic ductal adenocarcinoma

博士（医学）福島県立医科大

α-Synuclein and DJ-1 as Potential Biological Fluid Biomarkers for Parkinson’s Disease

Parkinson’s disease (PD) is the most common form of movement disorder and affects approximately 4% of the population aged over 80 years old. Currently, PD cannot be prevented or cured, and no single diagnostic biomarkers are available. Notably, recent studies suggest that two familial PD-linked molecules, α-synuclein and DJ-1, are present in cerebrospinal fluid (CSF) and that their levels may be altered during the progression of PD. In this regard, sensitive and accurate methods for evaluation of α-synuclein and DJ-1 levels in the CSF and blood have been developed, and the results suggest that the levels of both molecules are significantly decreased in the CSF in patients with PD compared with age-matched controls. Furthermore, specific detection and quantification of neurotoxic oligometric forms of α-synuclein in the blood using enzyme-linked immunosorbent assays might be expected as potential peripheral biomarkers for PD, although further validation is required. Currently, neither α-synuclein nor DJ-1 is satisfactory as a single biomarker for PD, but combinatory evaluation of these biological fluid molecules with other biomarkers and imaging techniques may provide reliable information for diagnosis of PD

Neuroinflammation in Parkinson's Disease and Related Disorders: A Lesson from Genetically Manipulated Mouse Models of α-Synucleinopathies

Neuroinflammation in Parkinson's disease (PD) is a chronic process that is associated with alteration of glial cells, including astrocytes and microglia. However, the precise mechanisms remain obscure. To better understand neuroinflammation in PD, we focused on glial activation in α-synuclein (αS) transgenic and related model mice. In the majority of αS transgenic mice, astrogliosis was observed concomitantly with accumulation of αS during the early stage of neurodegeneration. However, microglia were not extensively activated unless the mice were treated with lipopolysaccharides or through further genetic modification of other molecules, including familial PD risk factors. Thus, the results in αS transgenic mice and related model mice are consistent with the idea that neuroinflammation in PD is a double-edged sword that is protective in the early stage of neurodegeneration but becomes detrimental with disease progression

Transport in α\alpha-Sexithiophene Films

The field-effect mobility of hole polarons in $\alpha$-sexithiophene, measured in thin film transistors, was shown to be well fitted by Holstein's small polaron theory. Unfortunately, Holstein's formulation is based on an integral that does not converge. We show that the data are well fitted by a theory of polaron transport that was successful in accounting for mobility in molecular crystals of naphthalene.Comment: 10 pages, RevTex, one PostScript file aviable upon reques

Ground state properties of ferromagnetic metal/conjugated polymer interfaces

We theoretically investigate the ground state properties of ferromagnetic metal/conjugated polymer interfaces. The work is partially motivated by recent experiments in which injection of spin polarized electrons from ferromagnetic contacts into thin films of conjugated polymers was reported. We use a one-dimensional nondegenerate Su-Schrieffer-Heeger (SSH) Hamiltonian to describe the conjugated polymer and one-dimensional tight-binding models to describe the ferromagnetic metal. We consider both a model for a conventional ferromagnetic metal, in which there are no explicit structural degrees of freedom, and a model for a half-metallic ferromagnetic colossal magnetoresistance (CMR) oxide which has explicit structural degrees of freedom. The Fermi energy of the magnetic metallic contact is adjusted to control the degree of electron transfer into the polymer. We investigate electron charge and spin transfer from the ferromagnetic metal to the organic polymer, and structural relaxation near the interface. Bipolarons are the lowest energy charge state in the bulk polymer for the nondegenerate SSH model Hamiltonian. As a result electrons (or holes) transferred into the bulk of the polymer form spinless bipolarons. However, there can be spin density in the polymer localized near the interface.Comment: 7 figure