Channel-Aware Peer Selection in Multi-View Peer-to-Peer Multimedia Streaming

Motivated by the success of the Picture in Picture feature of the traditional TV, several commercial Peer-to-Peer Multi-Media Streaming (P2PMMS) applications now support the multi-view feature, with which a user can simultaneously watch multiple channels on its screen. This paper considers the peer selection problem in multi-view P2PMMS. This problem has been well studied in the traditional single-view P2PMMS; however, it becomes more complicated in multi-view P2PMMS, mainly due to the fact that a peer watching multiple channels joins multiple corresponding overlays. In this paper, we propose a novel peer selection algorithm, called Channel-Aware Peer Selection (CAPS), where a peer selects its neighboring peers based on the channel subscription of the system, in order to efficiently utilize the bandwidth of all peers in the system, especially those peers watching multiple channels. The results of a large-scale simulation with 10,000 peers and 4 channels shows that CAPS can significantly improve the system performance over the straightforward Random Peer Selection (RPS), which is widely used in single-view P2PMMS networks

Network Architectures for Live Peer-to-Peer Media Streaming

Peer-to-Peer (P2P) media streaming networks, motivated by the huge success of P2P file downloading networks, have recently attracted a lot of research interest. However, it is challenging to design P2P media streaming networks because of the stringent time constraints on the delivered media streams, which require more efficient and resilient overlay architectures. In this paper, we focus on live P2P media streaming networks, a promising application flourishing in the Internet and which requires the distribution of live (not stored) multimedia content to subscribers. We review the architectures for live P2P media streaming networks, and consider both overlay topologies and their construction

Variable Neighbor Selection in Live Peer-to-Peer Multimedia Streaming Networks

Data-driven (or swarming based) streaming is one of the popular ways to distribute live multimedia streaming traffic over Peer-to-Peer (P2P) networks. The efficiency and user satisfaction highly depend on the constructed overlays. The common neighbor selection algorithms in existing overlay construction schemes usually randomly select a fixed number of neighbors which satisfy the selection requirements, such as end-to-end delay or a peer\u27s sojourn time. However, this fixed random neighbor-selection algorithm (FRNS) neglects the peers\u27 upload bandwidth heterogeneity and therefore, the upload bandwidth cannot be efficiently used. In this paper, we propose a variable random neighbor-selection (VRNS) scheme to alleviate the problems due to bandwidth heterogeneity, and in which the number of neighbors with different upload bandwidths is dynamically determined by the statistical bandwidth information of the system. Our proposed scheme is shown to outperform FRNS based upon a large volume of carefully designed simulations

In Situ Fabrication of Polymeric Microcapsules by Ink-Jet Printing of Emulsions

Phase separation driven by solvent evaporation of emulsions can be used to create polymeric microcapsules. The combination of emulsion solvent evaporation with ink-jet printing allows the rapid fabrication of polymeric microcapsules at a target location on a surface. The ink is an oil-in-water emulsion containing in the dispersed phase a shell-forming polymer, a core-forming fluid that is a poor solvent for the polymer, and a low-boiling good solvent. After the emulsion is printed onto the substrate, the good solvent evaporates by diffusion through the aqueous phase, and the polymer and the poor solvent phase separate to form microcapsules. The continuous aqueous phase contains polyvinyl alcohol that serves as an emulsifier and a binder of the capsules to the substrate. This method is demonstrated for microcapsules with various shell-forming polymers (polystyrene, poly(methylmethacrylate) and poly(l-lactide)) and core-forming poor solvents (hexadecane and a 4-heptanone/sunflower oil mixture). Cargoes such as fluorescent dyes (Nile Red and tetracyanoquinodimethane) or active ingredients (e.g., the fungicide tebuconazole) can be encapsulated. Uniform microcapsules are obtained by printing emulsions containing monodisperse oil droplets produced in a microfluidic device. We discuss the physical parameters that need to be controlled for the successful fabrication of microcapsules in inkjet printing. The method for rapid, in situ encapsulation could be useful for controlled-release applications such as in agrochemical sprays, fragrances, functional coatings, and topical medicines

Linear Programming Models For Multi-Channel P2P Streaming Systems

Most of the commercial P2P video streaming deployments support hundreds of channels and are referred to as multichannel systems. Measurement studies show that bandwidth resources of different channels are highly unbalanced and thus recent research studies have proposed various protocols to improve the streaming qualities for all channels by enabling cross-channel cooperation among multiple channels. However, there is no general framework for comparing existing and potential designs for multi-channel P2P systems. The goal of this paper is to establish tractable models for answering the fundamental question in multi-channel system designs: Under what circumstances, should a particular design be used to achieve the desired streaming quality with the lowest implementation complexity? To achieve this goal, we first classify existing and potential designs into three categories, namely Naive Bandwidth allocation Approach (NBA), Passive Channel-aware bandwidth allocation Approach (PCA) and Active Channel-aware bandwidth allocation Approach (ACA). Then, we define the bandwidth satisfaction ratio as a performance metric to develop linear programming models for the three designs. The proposed models are independent of implementations and can be efficiently solved due to the linear property, which provides a way of numerically exploring the design space of multi-channel systems and developing closedform solutions for special systems

The effect of anti-VEGF drugs (bevacizumab and aflibercept) on the survival of patients with metastatic colorectal cancer (mCRC)

Significant progression has been achieved in the treatment of metastatic colorectal cancer (mCRC) in recent years. This has been partly attributed to successfully incorporating new drugs into combination chemotherapy. In addition to the traditional cytotoxic chemotherapeutic agents, molecularly targeted agents began to play an important role in the treatment of advanced solid tumors. To date, two classes of molecularly targeted agents have been approved for treatment of patients with mCRC: (1) antivascular endothelial growth factor (anti-VEGF) agents (such as bevacizumab and aflibercept) and (2) antiendothelial cell growth factor receptor (anti-EGFR) agents (such as cetuximab and panitumumab). Aflibercept is a new member of anti-VEGF agents which has demonstrated efficacy for treatment of mCRC. With the commencement of clinical trials and basic research into aflibercept, more data from the bedside and the bench have been obtained. This review will outline the application of anti-VEGF agents by reviewing clinic experiences of bevacizumab and aflibercept, and try to add perspectives on the use of anti-VEGF agents in mCRC

The phylogeny and taxonomy of Upretia (Caloplacoideae, Teloschistaceae), reveal three new species from Southwestern China

Several specimens of Upretia from Southwest China are morphologically and phylogenetically distinct from currently recognized species in the genus. These specimens are here accommodated within a new species, Upretia zeorina Li J. Li & Printzen. It is characterized by an areolate to squamulose thallus with brown to blackish brown upper surface, pruinose, zeorine type apothecia, black discs, narrowly bacilliform conidia, and the production of gyrophoric acid. Two other specimens of Upretia from China are distinct from currently accepted species and tentatively referred to as Upretia sp. 1 and Upretia sp. 2. A key to all known species of Upretia is also provided