Passive Thermal Control of the Primordial Inflation Polarization Explorer (PIPER) Flight Electronics

The scientific balloon program at NASA offers an exciting and open area of opportunity for testing new technologies and for conducting meaningful experimentation at a fraction of the cost of a space mission. This paper outlines a simple thermal model developed and employed for the Primordial Inflation Polarization ExplorER (PIPER). The sub-orbital environment that PIPER operates in hosts an interesting mix of atmospheric and space thermal challenges. The work done was to mitigate thermal loads and passively cool the payload's exterior mounted electronics at an altitude of 36.6 km. This was done by characterizing the thermal environment and then designing solutions for the heat loads through a combined radiation and conduction passive cooling radiator system thermal model. Despite the simplicity and subsequent limitations of the model, as well as some unexpected payload operational events, the model produced results between 0.31% and 11.8% difference between the predicted values and measured average temperatures. From these results, the model was able to successfully provide estimates for the electronics temperatures. Additional flights will be needed to eliminate unknowns encountered in this flight in order to further refine the model for higher accuracy

Child Labor Trafficking in the United States: A Hidden Crime

Emerging research brings more attention to labor trafficking in the United States. However, very few efforts have been made to better understand or respond to labor trafficking of minors. Cases of children forced to work as domestic servants, in factories, restaurants, peddling candy or other goods, or on farms may not automatically elicit suspicion from an outside observer as compared to a child providing sexual services for money. In contrast to sex trafficking, labor trafficking is often tied to formal economies and industries, which often makes it more difficult to distinguish from ”legitimate” work, including among adolescents. This article seeks to provide examples of documented cases of child labor trafficking in the United States, and to provide an overview of systemic gaps in law, policy, data collection, research, and practice. These areas are currently overwhelmingly focused on sex trafficking, which undermines the policy intentions of the Trafficking Victims Protection Act (2000), the seminal statute criminalizing sex and labor trafficking in the United States, its subsequent reauthorizations, and international laws and protocols addressing human trafficking

P16/Ki-67 Immunostaining is Useful in Stratification of Atypical Metaplastic Epithelium of the Cervix

Cervical metaplastic squamous epithelium exhibiting atypia insufficient for a diagnosis of cervical intraepithelial neoplasia (CIN) is usually reported as “atypical squamous metaplasia” (ASM). Stratification impacts treatment since the differential is often between reactive and high grade CIN (CIN II, III). Diagnosis with H&E is associated with low intra/interobserver concurrence. P16/Ki-67 immunostains are helpful to assess cervical biopsies for HPV-associated lesions but staining in metaplastic squamous epithelium has received little attention. This study aims to establish staining characteristics of metaplastic squamous epithelium and determine if p16/Ki-67 is useful in ASM stratification. 80 cervical biopsies containing morphologically normal and dysplastic squamous metaplasia were retrieved to determine the staining characteristics of metaplastic epithelium utilizing p16/Ki-67 immunostains. These included 21 benign squamous metaplasia (BSM) from benign cervices, 15 BSM present adjacent to HPV/CIN lesions, and 44 CIN involving squamous metaplasia. Serial sections with controls were stained for p16 and Ki-67 and in-situ hybridization (ISH) for low-risk (LR) and high-risk (HR) HPV was performed. P16 was recorded as negative, spotty, or band-like. Ki-67 was recorded as positive when present in >50% of lesional nuclei. Results were correlated with H&E diagnosis. 95% of the BSMs, whether from normal cervices or adjacent to HPV/CIN were p16/Ki-67 negative. 81% HG CINs involving squamous metaplasia were p16 band/Ki-67 positive. Low grade CIN (CIN I) involving metaplastic epithelium showed a broad distribution of p16/Ki-67 staining patterns. Based on these criteria, 20 ASM were evaluated. 10% of the ASM cases were p16 band/Ki-67 positive indicating HG CIN. 60% of the ASMs were p16/Ki-67 negative indicating reactive change (all with the exception of one case being HPV negative). The remaining 30% of the ASM cases showed variable positivity for p16 and Ki-67 and could not be stratified into the two categories. Thus p16/Ki-67 staining is helpful in stratification of ASM as reactive or CIN

Performance based staffing for detectives

Suggests that performance based selection of detectives is best for the department and community

Nos Non Abolere Ordo Lectionum: The History of the Historic Lectionary as Retained by the Lutheran Church

The history of the Historic Lectionary from a Lutheran perspective provided great insight into its development and retention in the 21st century. This paper reviews the long history of the Historic Lectionary, previously the lectionary of the Western church, and compares its value in light of recent lectionary developments. This study reveals a Lutheran perspective in light of the lectionary debate in the Lutheran Church–Missouri Synod and succinctly sets forth centuries of lectionary history in the West