12,348 research outputs found
Perceptual impairment in face identification with poor sleep
Previous studies have shown impaired memory for faces following restricted sleep. However, it is not known whether lack of sleep impairs performance on face identification tasks that do not rely on recognition memory, despite these tasks being more prevalent in security and forensic professionsâfor example, in photo-ID checks at national borders. Here we tested whether poor sleep affects accuracy on a standard test of face-matching ability that does not place demands on memory: the Glasgow Face-Matching Task (GFMT). In Experiment 1, participants who reported sleep disturbance consistent with insomnia disorder show impaired accuracy on the GFMT when compared with participants reporting normal sleep behaviour. In Experiment 2, we then used a sleep diary method to compare GFMT accuracy in a control group to participants reporting poor sleep on three consecutive nightsâand again found lower accuracy scores in the short sleep group. In both experiments, reduced face-matching accuracy in those with poorer sleep was not associated with lower confidence in their decisions, carrying implications for occupational settings where identification errors made with high confidence can have serious outcomes. These results suggest that sleep-related impairments in face memory reflect difficulties in perceptual encoding of identity, and point towards metacognitive impairment in face matching following poor sleep
Which sexual abuse victims receive a forensic medical examination? : The impact of Children\u27s Advocacy Centers
Abstract Objective This study examines the impact of Children\u27s Advocacy Centers (CAC) and other factors, such as the child\u27s age, alleged penetration, and injury on the use of forensic medical examinations as part of the response to reported child sexual abuse. Methods This analysis is part of a quasi-experimental study, the Multi-Site Evaluation of Children\u27s Advocacy Centers, which evaluated four CACs relative to within-state non-CAC comparison communities. Case abstractors collected data on forensic medical exams in 1,220 child sexual abuse cases through review of case records. Results Suspected sexual abuse victims at CACs were two times more likely to have forensic medical examinations than those seen at comparison communities, controlling for other variables. Girls, children with reported penetration, victims who were physically injured while being abused, White victims, and younger children were more likely to have exams, controlling for other variables. Non-penetration cases at CACs were four times more likely to receive exams as compared to those in comparison communities. About half of exams were conducted the same day as the reported abuse in both CAC and comparison communities. The majority of caregivers were very satisfied with the medical professional. Receipt of a medical exam was not associated with offenders being charged. Conclusions Results of this study suggest that CACs are an effective tool for furthering access to forensic medical examinations for child sexual abuse victims
Water Delivery and Giant Impacts in the 'Grand Tack' Scenario
A new model for terrestrial planet formation (Hansen 2009, Walsh et al. 2011)
has explored accretion in a truncated protoplanetary disk, and found that such
a configuration is able to reproduce the distribution of mass among the planets
in the Solar System, especially the Earth/Mars mass ratio, which earlier
simulations have generally not been able to match. Walsh et al. tested a
possible mechanism to truncate the disk--a two-stage, inward-then-outward
migration of Jupiter and Saturn, as found in numerous hydrodynamical
simulations of giant planet formation. In addition to truncating the disk and
producing a more realistic Earth/Mars mass ratio, the migration of the giant
planets also populates the asteroid belt with two distinct populations of
bodies--the inner belt is filled by bodies originating inside of 3 AU, and the
outer belt is filled with bodies originating from between and beyond the giant
planets (which are hereafter referred to as `primitive' bodies).
We find here that the planets will accrete on order 1-2% of their total mass
from primitive planetesimals scattered onto planet-crossing orbits during the
formation of the planets. For an assumed value of 10% for the water mass
fraction of the primitive planetesimals, this model delivers a total amount of
water comparable to that estimated to be on the Earth today. While the radial
distribution of the planetary masses and the dynamical excitation of their
orbits are a good match to the observed system, we find that the last giant
impact is typically earlier than 20 Myr, and a substantial amount of mass is
accreted after that event. However, 5 of the 27 planets larger than half an
Earth mass formed in all simulations do experience large late impacts and
subsequent accretion consistent with the dating of the Moon-forming impact and
the estimated amount of mass accreted by Earth following that event
Outcomes from COVID-19 Clinical Trials in Hospitalized Patients: Seeking the Truth That Matters
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Broadcasting Flu Messages â Citywide Transmission and Community Reception: An Evaluation of Ready New Yorkâs pandemic influenza outreach campaign
Public health risk communication is a central feature of New York Cityâs pandemic flu preparedness plan. Particularly in the early stages of a pandemic, before effective therapeutic measures are available, non-pharmaceutical interventions such as social distancing, personal protective hygiene, and voluntary isolation are critical strategies for suppressing the spread of a novel viral strain. New York City health and emergency management officials have decided to use the cityâs risk communication structure â the Office of Emergency Managementâs Ready New York outreach and dissemination capacities â as one of the primary means to communicate pandemic flu health messages. In October 2008, NCDP contracted with Public Health Solutions and the Office of Emergency Management (OEM) to evaluate the reach and effectiveness of its planned Ready NY Pandemic Flu community outreach campaign
Culture of airway epithelial cells from neonates sampled within 48-hours of birth
Peer reviewedPublisher PD
Who abandons embryos after IVF?
This investigation describes features of in vitro fertilisation (IVF) patients who never returned to claim their embryos following cryopreservation. Frozen embryo data were reviewed to establish communication patterns between patient and clinic; embryos were considered abandoned when 1) an IVF patient with frozen embryo/s stored at our facility failed to make contact with our clinic for \u3e 2 yrs and 2) the patient could not be located after a multi-modal outreach effort was undertaken. For these patients, telephone numbers had been disconnected and no forwarding address was available. Patient, spouse and emergency family contact/s all escaped detection efforts despite an exhaustive public database search including death records and Internet directory portals. From 3244 IVF cycles completed from 2000 to 2008, \u3e or = 1 embryo was frozen in 1159 cases (35.7%). Those without correspondence for \u3e 2 yrs accounted for 292 (25.2%) patients with frozen embryos; 281 were contacted by methods including registered (signature involving abandoned embryos did not differ substantially from other patients. The goal of having a baby was achieved by 10/11 patients either by spontaneous conception, adoption or IVF. One patient moved away with conception status unconfirmed. The overall rate of embryo abandonment was 11/1159 (\u3c 1%) in this IVF population. Pre-IVF counselling minimises, but does not totally eliminate, the problem of abandoned embryos. As the number of abandoned embryos from IVF accumulates, their fate urgently requires clarification. We propose that clinicians develop a policy consistent with relevant Irish Constitutional provisions to address this medical dilemma
On the Fence: The Impact of Education on Support for Electric Fencing to Prevent Conflict between Humans and Baboons in Kommetjie, South Africa
Few studies test whether education can help increase support for wildlife management interventions. This mixed methods study sought to test the importance of educating a community on the use of a baboon-proof electric fence to mitigate negative interactions between humans and Chacma baboons (Papio ursinus) in a residential suburb of the City of Cape Town, South Africa. An educational video on the welfare, conservation and lifestyle benefits of a baboon-proof electric fence was included in a short online survey. The positioning of the video within the survey was randomised either to fall before or after questions probing the level of support for an electric fence. The results showed that watching the video before most survey questions increased the average marginal probability of supporting an electric fence by 15 percentage points. The study also explored whether the educational video could change people’s minds. Those who saw the video towards the end of the survey were questioned again about the electric fence. Many changed their minds after watching the video, with support for the fence increasing from 36% to 50%. Of these respondents, the results show that being female raised the average marginal probability of someone changing their mind in favour of supporting the fence by 19%. Qualitative analysis revealed that support for or against the fence was multi-layered and that costs and concern for baboons were not the only relevant factors influencing people’s choices. Conservation often needs to change people’s behaviours. We need to know what interventions are effective. We show in the real world that an educational video can be effective and can moderately change people’s opinions and that women are more likely to change their position in light of the facts than men. This study contributes to the emerging literature on the importance of education in managing conservation conflicts and the need for evidence-based interventions
Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression.
Vascular cell adhesion molecule-1 (VCAM-1) plays important roles in development and inflammation. Tumor necrosis factor-α (TNF-α) and focal adhesion kinase (FAK) are key regulators of inflammatory and integrin-matrix signaling, respectively. Integrin costimulatory signals modulate inflammatory gene expression, but the important control points between these pathways remain unresolved. We report that pharmacological FAK inhibition prevented TNF-α-induced VCAM-1 expression within heart vessel-associated endothelial cells in vivo, and genetic or pharmacological FAK inhibition blocked VCAM-1 expression during development. FAK signaling facilitated TNF-α-induced, mitogen-activated protein kinase activation, and, surprisingly, FAK inhibition resulted in the loss of the GATA4 transcription factor required for TNF-α-induced VCAM-1 production. FAK inhibition also triggered FAK nuclear localization. In the nucleus, the FAK-FERM (band 4.1, ezrin, radixin, moesin homology) domain bound directly to GATA4 and enhanced its CHIP (C terminus of Hsp70-interacting protein) E3 ligase-dependent polyubiquitination and degradation. These studies reveal new developmental and anti-inflammatory roles for kinase-inhibited FAK in limiting VCAM-1 production via nuclear localization and promotion of GATA4 turnover
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