2,121 research outputs found

    Performance of school-age children of prenatal cocaine exposure: Five case studies

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    The purpose of this study was to examine the social and learning performance of school age children of prenatal cocaine exposure. The Behavioral Assessment System for Children (BASC) was used along with interviews, observations and document analysis for each individual case studied. The data collected through these methods was coded and examined for patterns and relationships in each case, and across cases.;Data analysis revealed that each case varied in the effects exhibited on a continuum from subtle to severe, as indicated in the literature. Social and behavioral patterns appeared to be most severely affected, while the language area was found to be within normal parameters for children their age. Additionally, all cases experienced tremendous environmental factors which may have impacted their performance such as trauma, abuse, and passive exposure to cocaine and other drugs

    Managing Global Training Utilizing Distance Learning Technologies and Techniques: The United States Army Readiness Training

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    Distance learning (e-learning) is expanding at a very rapid pace as organizations throughout the world search for economical, responsive, and effective means to train workers to meet the challenges of the information age workplace. The Army Distance Learning Program (TADLP) model is discussed in the context of the global e-learning environment. Both e-learning infrastructure and management issues are identified, with emphasis on: (1) developing policy, (2) measuring performance, (3) managing resources, (4) maintaining standards, and (5) satisfying users. The TADLP program is challenging to manage effectively, and difficult to accurately assess program outcomes. The TADLP program is shown to have a well-executed infrastructure plan, quality management of both facilities and services by contractor-supplied staff, and well-designed classrooms. However, the program suffers from limited courseware, creating a bottleneck for full program utilization. A discussion follows relating the Army program to public and private e-learning programs and expectations.

    Emerging regulatory issues for human stem cell medicine

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    20 pages.Discusses the issues involved in regulating the products of stem cell research in the United Kingdom

    Evaluating the Impact of a SNAP Challenge on University Participant Attitudes Toward Poverty

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    Objective: The purpose of this study was to evaluate whether a week-long SNAP Challenge completed by university participants influenced perceptions about poverty. Design: Pretest and posttest questionnaires measured changes in attitudes toward poverty after the SNAP Challenge using the Attitude Toward Poverty Short Form scale comprised of three factors: Personal Deficiency, Stigma, and Structural Perspective. Dispositional empathy was measured with the Interpersonal Reactivity Index and analyzed as a potential mediating variable of attitude change. Subjects: Student and non-student subjects were recruited from Winthrop University. Four hundred forty-six pretest questionnaires were initiated, 363 were completed, and 363 were eligible for inclusion. One hundred forty-three posttest questionnaires were initiated, 121 were completed, and 117 were eligible for inclusion. Eighty matched pairs met study inclusion criteria. Results: Attitudes toward poverty related to Stigma, but not Personal Deficiency or Structural Perspective improved significantly (t(79) = -3.421, p = .001, d = 0.38). There was no correlation between days participants completed the SNAP Challenge and changes in attitudes toward poverty. Human Nutrition participants did not differ from other participants in the magnitude of attitude change observed. Empathy did not mediate the relationship between the SNAP Challenge experience and attitude change. Conclusion: The SNAP Challenge improved attitudes related to Stigma. It offers a unique experiential learning method for broadening perspectives about poverty. The Challenge should be integrated with classroom teaching about poverty and re-evaluated

    The Health of Aging Lesbian, Gay and Bisexual Adults in California

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    Examines rates of diabetes, hypertension, poor mental health, physical disability, and fair or poor self-reported health status among homosexual adults ages 50 to 70 compared with their heterosexual peers. Recommends enhancing policies and practices

    The Status of Women and Entrepreneurship in Utah

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    Is Utah a good place for women to start and run businesses? You may be misled if you rely on what the media has been reporting the past few years about women in Utah. A host of state rankings has continually put Utah as one of the worst states in the nation for women. For example, Utah did not fare well in the WalletHubā€™s recent ā€œ2015ā€™s Best and Worst States for Womenā€™s Equality.ā€ Utah was also included in the New York Postā€™s ā€œ5 Places Women Shouldnā€™t Spend Their Travel Dollars,ā€ and in 2014 Utah was ranked as the worst state for women on the ā€œ10 Worst States for Womenā€ list at 24/7Wallst.com. In addition, Utah did poorly in the Center for American Progress report, ā€œThe State of Women in America: A 50-State Analysis of How Women are Faring Across the Nation.ā€4 Although it is clear that we need to improve the representation of women in leadership and decision-making roles, in the gender wage gap, and in funding for programs and efforts that support the well-being of Utah women, these rankings were based on limited criteria. However, one area not included in these criteria that would have strengthened Utah rankings is women and entrepreneurship

    Rapid determination of the active fraction of DNA repair glycosylases: a novel fluorescence assay for trapped intermediates

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    Current methods to measure the fraction of active glycosylase molecules in a given enzyme preparation are slow and cumbersome. Here we report a novel assay for rapidly determining the active fraction based on molecular accessibility of a fluorescent DNA minor groove binder, 4ā€²,6-diamidino-2-phenylindole (DAPI). Several 5,6-dihydrouracil-containing (DHU) DNA substrates were designed with sequence-dependent DAPI-binding sites to which base excision repair glycosylases were covalently trapped by reduction. Trapped complexes impeded the association of DAPI in a manner dependent on the enzyme used and the location of the DAPI-binding site in relation to the lesion. Of the sequences tested, one was shown to give an accurate measure of the fraction of active molecules for each enzyme tested from both the Fpg/Nei family and HhH-GPD Nth superfamily of DNA glycosylases. The validity of the approach was demonstrated by direct comparison with current gel-based methods. Additionally, the results are supported by in silico modeling based on available crystal structures

    Risk and protective factors for suicidality among lesbian, gay, bisexual, transgender and queer (LGBTQ+) young people, from countries with a high global acceptance index (GAI), within the context of the socio-ecological model: A scoping review

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    Introduction: Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) young people experience higher prevalence rates of suicidality than their heterosexual and/or cisgender peers. However, there is limited research that can inform suicide prevention efforts. Our aim was to synthesize quantitative, qualitative, and mixed methods research on risk and protective factors among LGBTQ+ young people, from countries with a high Global Acceptance Index.Methods: A scoping review guided by Arksey and O'Malley's fiveā€stage framework, using the Preferred Reporting Items for Systematic Reviews and Metaā€analysis Extension for Scoping Reviews protocol. Five databases and grey literature were searched for relevant studies. Identified factors were clustered by thematic type, according to the socioā€ecological model to identify empirical trends and knowledge gaps. The mixed methods appraisal tool was used for quality assessment of studies. Results: Sixtyā€six studies met our inclusion criteria. Overall, 59 unique risk factors and 37 unique protective factors were identified. Key risk factors include past suicidality, adverse childhood experiences, internalized queerphobia, minority stress, interpersonal violence, bullying, familial conflict, and antiā€LGBTQ+ policies/ legislation. Key protective factors include selfā€affirming strategies, adult/peer support, atā€school safety, access to inclusive healthcare, family connectedness, positive coming out experiences, genderā€affirming services and LGBTQ+ inclusive policies and legislation.Conclusions: Overall, our findings affirm that multiple risk and protective factors, at all levels of the socioā€ecological model, interact in complex, unique and diverse ways upon suicidality among LGBTQ+ young people. Implications for suicide prevention are discussed. Further empirical studies are required, particularly at the communities, policies, and societal levels of the socioā€ecological model, and these studies should include a focus on protective factors and significant withinā€group differences

    The ISCIP Analyst, Volume XVI, Issue 5

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    This repository item contains a single issue of The ISCIP Analyst, an analytical review journal published from 1996 to 2010 by the Boston University Institute for the Study of Conflict, Ideology, and Policy
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