1,728 research outputs found

    Child abuse registration, fetal growth, and preterm birth: a population based study

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    Objectives: To study the relation of intra-uterine growth and gestational age with child protection registration in a 20 year whole population birth cohort. Setting: West Sussex area of England. Study design: Retrospective whole population birth cohort. Outcomes: Child protection registration; individual categories of registration—sexual abuse, physical abuse, emotional abuse, and neglect. Population and participants: 119 771 infants born in West Sussex between January 1983 and December 2001 with complete data including birth weight, gestational age, maternal age, and postcode. Results: In all categories of registration a linear trend was noted such that the lower the birth weight z score the higher the likelihood of child protection registration. Similar trends were noted for gestational age. All these trends were robust to adjustment for maternal age and socioeconomic status. Conclusions: The results of this study suggest that lower levels of fetal growth and shorter gestational duration are associated with increased likelihood of child protection registration in all categories including sexual abuse independent of maternal age or socioeconomic status. This study does not permit comment on whether poor fetal growth or preterm birth predispose to child abuse and neglect or the association arises because they share a common pathway

    Non-Parametric Confidence Intervals for Generalized Lorenz Curve using Modified Empirical Likelihood

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    The Lorenz curve portrays the inequality of income distribution. In this article, we develop three modified empirical likelihood (EL) approaches including adjusted empirical likelihood, transformed empirical likelihood, and transformed adjusted empirical likelihood to construct confidence intervals for the generalized Lorenz ordinate. We have shown that the limiting distribution of the modified EL ratio statistics for the generalized Lorenz ordinate follows the scaled Chi-Squared distributions with one degree of freedom. The coverage probabilities and mean lengths of confidence intervals are compared of the proposed methods with the traditional EL method through simulations under various scenarios. Finally, the proposed methods are illustrated using a real data application to construct confidence intervals.Comment: 20 page

    Community Broadband Initiatives: what makes them successful and why?

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    ACKNOWLEDGEMENTS The authors would like to thank the UK Engineering and Physical Sciences Research Council for their support through grant number (EP/G066051/1) Digital Economy Hub and grant number (EP/K003585/1) Communities and Cultures Network+Peer reviewedPublisher PD

    Is There an Association of Physical Activity with Brain Volume, Behavior, and Day-to-day Functioning? A Cross Sectional Design in Prodromal and Early Huntington Disease

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    Background: Huntington disease (HD) is a genetic neurodegenerative disease leading to progressive motor, cognitive, and behavioral decline. Subtle changes in these domains are detectable up to 15 years before a definitive motor diagnosis is made. This period, called prodromal HD, provides an opportunity to examine lifestyle behaviors that may impact disease progression. Theoretical Framework: Physical activity relates to decreased rates of brain atrophy and improved cognitive and day-to-day functioning in Alzheimer disease and healthy aging populations. Previous research has yielded mixed results regarding the impact of physical activity on disease progression in HD and paid little attention to the prodromal phase. Methods: We conducted analyses of associations among current physical activity level, current and retrospective rate of change for hippocampus and striatum volume, and cognitive, motor, and day-to-day functioning variables. Participants were 48 gene-expanded cases with prodromal and early-diagnosed HD and 27 nongene-expanded control participants. Participants wore Fitbit Ultra activity monitors for three days and completed the self-reported International Physical Activity Questionnaire (IPAQ). Hippocampal and striatal white matter volumes were measured using magnetic resonance imaging. Cognitive tests included the Stroop Color and Word Test, and the Symbol Digit Modalities Test (SDMT). Motor function was assessed using the Unified Huntington’s Disease Rating Scale total motor score (TMS). Day-to-day functioning was measured using the World Health Organization Disability Assessment Schedule (WHODAS) version 2.0. Results: Higher Fitbit activity scores were significantly related to better scores on the SDMT and WHODAS in case participants but not in controls. Fitbit activity scores tracked better with TMS scores in the group as a whole, though the association did not reach statistical significance in the case participants. Higher Fitbit activity scores related to less day-to-day functioning decline in retrospective slope analyses. Fitbit activity scores did not differ significantly between cases and controls. Conclusions: This is the first known study examining the associations between activity level and imaging, motor, cognitive, and day-to-day functioning outcomes in prodromal and early HD. Preliminary results suggest physical activity positively correlates with improved cognitive and day-to-day functioning and possibly motor function in individuals in the prodromal and early phase of the condition

    Investigating the physical properties of transiting hot Jupiters with the 1.5-m Kuiper Telescope

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    We present new photometric data of 11 hot Jupiter transiting exoplanets (CoRoT-12b, HAT-P-5b, HAT-P-12b, HAT-P-33b, HAT-P-37b, WASP-2b, WASP-24b, WASP-60b, WASP-80b, WASP-103b, XO-3b) in order to update their planetary parameters and to constrain information about their atmospheres. These observations of CoRoT-12b, HAT-P-37b and WASP-60b are the first follow-up data since their discovery. Additionally, the first near-UV transits of WASP-80b and WASP-103b are presented. We compare the results of our analysis with previous work to search for transit timing variations (TTVs) and a wavelength dependence in the transit depth. TTVs may be evidence of a third body in the system and variations in planetary radius with wavelength can help constrain the properties of the exoplanet's atmosphere. For WASP-103b and XO-3b, we find a possible variation in the transit depths that may be evidence of scattering in their atmospheres. The B-band transit depth of HAT-P-37b is found to be smaller than its near-IR transit depth and such a variation may indicate TiO/VO absorption. These variations are detected from 2-4.6σ\sigma, so follow-up observations are needed to confirm these results. Additionally, a flat spectrum across optical wavelengths is found for 5 of the planets (HAT-P-5b, HAT-P-12b, WASP-2b, WASP-24b, WASP-80b), suggestive that clouds may be present in their atmospheres. We calculate a refined orbital period and ephemeris for all the targets, which will help with future observations. No TTVs are seen in our analysis with the exception of WASP-80b and follow-up observations are needed to confirm this possible detection.Comment: 18 pages, 7 figures, 9 Tables. Light Curves available online. Accepted to MNRAS (2017 August 25

    The Transcendence of the Social: Durkheim, Weismann, and the Purification of Sociology

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    Building on Fox Keller’s acute genealogy of the nature–nurture opposition as located in a certain specific social, cultural, and political history in the late nineteenth century (2010), in this paper, I address a parallel problem: the making of a really modern (i.e., non-biological) sociology nearly at the same time as the “hard disjunction” (Keller, 2010) between heredity and the environment, nature and nurture, was made. I argue rather provocatively that traces of borrowing from hard heredity to sociology can be seen in Durkheim’s strategic usage of Weismann to destroy Lamarckian sociology. The transcendence of the social in Durkheim is entirely isomorphic to Weismann’s transcendence of the germ plasm: in both cases, they aimed to construct objective realities, radically independent and exterior from individual tendencies and peculiarities. Weismann offered Durkheim an important scientific companion to make boundaries between sociology and biology. In a Latourian sense (Latour, 1993), the purification strategy of Durkheim was actually helped by a hybridization with Weismann’s biology. In conclusion, by taking Weismann as an anticipator of the genetics revolution a few years later, I argue for a profound complicity between twentieth century non-biological sociology and genetics. They both made space for a neat distinction between biological heredity and sociocultural transmission, heredity, and heritage. If sociology and genetics thought of themselves as rivals and even enemies in explaining social facts, they should reconsider their positions
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