29 research outputs found

    El primado de la certeza : sobre la pérdida de la realidad en el realismo moderno

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    Fil: Wald, Berthold

    Josef Pieper como filósofo social

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    We reproduce here the presentation held by Berthold Wald in the International Congress “Josef Pieper and Contemporary Thought”, organized in 2005 by UCA for Josef Pieper’s centennial. In his youth, Pieper was involved in sociology and became interested in subjectsregarding the situation of the proletariat and the reconstruction of society. The author shows the political and social thought present in Pieper’s less known works and the synthesis he accomplished through the integration of empirical knowledge with a philosophical foundationof the social order.Aquí se reproduce la exposición que presentó Berthold Wald en el Congreso Internacional titulado “Josef Pieper y el pensamiento contemporáneo”, que se llevó a cabo en la UCA en el año 2005 con motivo del centenario del nacimiento del filósofo alemán. Pieper conoció dejoven la sociología y se involucró temprano con la temática proletaria y con la reconstrucción de la sociedad. El autor trae a la luz las consideraciones políticas y sociales que se encuentran en las obras menos conocidas de Pieper poniendo de relieve la síntesis que éste realizó integrando el conocimiento empírico con una fundamentación filosófica del orden social

    Folate catabolites in spot urine as non-invasive biomarkers of folate status during habitual intake and folic acid supplementation.

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    Folate status, as reflected by red blood cell (RCF) and plasma folates (PF), is related to health and disease risk. Folate degradation products para-aminobenzoylglutamate (pABG) and para-acetamidobenzoylglutamate (apABG) in 24 hour urine have recently been shown to correlate with blood folate. Since blood sampling and collection of 24 hour urine are cumbersome, we investigated whether the determination of urinary folate catabolites in fasted spot urine is a suitable non-invasive biomarker for folate status in subjects before and during folic acid supplementation. Immediate effects of oral folic acid bolus intake on urinary folate catabolites were assessed in a short-term pre-study. In the main study we included 53 healthy men. Of these, 29 were selected for a 12 week folic acid supplementation (400 µg). Blood, 24 hour and spot urine were collected at baseline and after 6 and 12 weeks and PF, RCF, urinary apABG and pABG were determined. Intake of a 400 µg folic acid bolus resulted in immediate increase of urinary catabolites. In the main study pABG and apABG concentrations in spot urine correlated well with their excretion in 24 hour urine. In healthy men consuming habitual diet, pABG showed closer correlation with PF (rs = 0.676) and RCF (rs = 0.649) than apABG (rs = 0.264, ns and 0.543). Supplementation led to significantly increased folate in plasma and red cells as well as elevated urinary folate catabolites, while only pABG correlated significantly with PF (rs = 0.574) after 12 weeks. Quantification of folate catabolites in fasted spot urine seems suitable as a non-invasive alternative to blood or 24 hour urine analysis for evaluation of folate status in populations consuming habitual diet. In non-steady-state conditions (folic acid supplementation) correlations between folate marker (RCF, PF, urinary catabolites) decrease due to differing kinetics

    Epigenetic associations in relation to cardiovascular prevention and therapeutics

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    Josef Pieper como filósofo social

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    Intelligent Design—Fundamentalismus oder unbequeme Herausforderung? [Intelligent Design—Fundamentalism or Uncomfortable Challenge?]

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    Order and change in nature have been for a long time understood in philosophy and theology as founded in divine reason. In the neo-Darwinist theory of evolution, their explanation is reduced to material change without reason. Molecular biologists like M. Behe and W. Demski argue that any reductionist explanation of living beings must be wrong. The evolution of irreducible complex structures is impossible on the basis of random variation and natural selection alone, and must be the result of intelligent design. The article argues that ID-theory, unlike Biblical Creationism, is a challenge for neo-Darwinism and for modern theology as well—for, unlike the Roman magisterium, many Catholic theologians try to harmonize reductive explanation with the notion of creation
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