A model approach for in- and outflow calculation of upper lake constance —An investigation of a 60 year time span and observations about the flood of 1999

AbstractThe revised empirical model for in- and outflow calculation of Upper Lake Constance has provided satisfying results supported by measured values. The given model was implemented to simulate total water inputs of the lake during the period from 1941 to 2000 with emphasis on the flood conditions of 1999. Analysis of annual water input development reveals a tendency toward slight increases until the 1960s. Thereafter, a reduction in inputs can be noted. This trend probably continues to hold true to present. Weather conditions of given individual years have caused distinct fluctuations to the water budget.Unusual meteorological conditions led to extreme flooding in early May of 1999. Daily water inputs of up to 200 mio m3 generated the highest water levels ever observed for this time of the year. Continual extraordinarily high water inputs occurring from February until July and then again from September until the end of 1999 resulted in the second largest annual total water input recorded since 1941

Speech Synthesis Evaluation—State-of-the-Art Assessment and Suggestion for a Novel Research Program

Wagner P, Beskow J, Betz S, et al. Speech Synthesis Evaluation—State-of-the-Art Assessment and Suggestion for a Novel Research Program. In: Proceedings of the 10th Speech Synthesis Workshop (SSW10). 2019.Speech synthesis applications have become an ubiquity, in navigation systems, digital assistants or as screen or audio book readers. Despite their impact on the acceptability of the systems in which they are embedded, and despite the fact that different applications probably need different types of TTS voices, TTS evaluation is still largely treated as an isolated problem. Even though there is strong agreement among researchers that the mainstream approaches to Text-to-Speech (TTS) evaluation are often insufficient and may even be misleading, there exist few clear-cut suggestions as to (1) how TTS evaluations may be realistically improved on a large scale, and (2) how such improvements may lead to an informed feedback for system developers and, ultimately, better systems relying on TTS. This paper reviews the current state-of-the-art in TTS evaluation, and suggests a novel user-centered research program for this area

Cell Origin of Human Mesenchymal Stem Cells Determines a Different Healing Performance in Cardiac Regeneration

The possible different therapeutic efficacy of human mesenchymal stem cells (hMSC) derived from umbilical cord blood (CB), adipose tissue (AT) or bone marrow (BM) for the treatment of myocardial infarction (MI) remains unexplored. This study was to assess the regenerative potential of hMSC from different origins and to evaluate the role of CD105 in cardiac regeneration. Male SCID mice underwent LAD-ligation and received the respective cell type (400.000/per animal) intramyocardially. Six weeks post infarction, cardiac catheterization showed significant preservation of left ventricular functions in BM and CD105+-CB treated groups compared to CB and nontreated MI group (MI-C). Cell survival analyzed by quantitative real time PCR for human GAPDH and capillary density measured by immunostaining showed consistent results. Furthermore, cardiac remodeling can be significantly attenuated by BM-hMSC compared to MI-C. Under hypoxic conditions in vitro, remarkably increased extracellular acidification and apoptosis has been detected from CB-hMSC compared to BM and CD105 purified CB-derived hMSC. Our findings suggests that hMSC originating from different sources showed a different healing performance in cardiac regeneration and CD105+ hMSC exhibited a favorable survival pattern in infarcted hearts, which translates into a more robust preservation of cardiac function

XI concurso internacional de canto Francisco Viñas

Programa del XI concurs internacional de cant Francesc Viñas celebrada el novembre de 1973 amb l'Orquestra del Gran Teatre del Liceu dirigida per G. Pérez Busquier. Al jurat hi havia R. Vuataz, C. A. Pizzini, J. Arnau, C. Badia, K. Borg, M. Favero, Y. Le Marc-Hadour, J. Micheau, E. Muñez, J. Pich Santasusana, N. Procter, H. Reutter i L. Prats. Els concursants van ser R. M. Buttkus, H. Clemens, H. Eckels, K. J. Kemper, J. Tomás, M. Fontana, L. Lima, M. Boateng-Toncar, H. Schwenzer, M. Baeta, V. De Kanel, M. Wunder Louzada, A. Bagdassarian, G. Duplessis, E. Blahova, M. Clarke, C. Decamp, D. González, A. Molero, J. L. Ochando, J. Poch, M. Ribas, M. Rodrigo, J. Ruiz, A. Anderson, J. Bardi, L. Clark-Anderson, E. Colón, P. Goldstein, R. Harris, V. Paton, I. Bernard, M. H. Burger, M. Lapierre, J. Manric, H. Legito, M. Parker, M. Spark, M. Barbacini, G. Cianella, R. Guiso, G. Pastorello, E. Maruyama, M. Cosmescu, A. Covali, A. Nemes, C. Pop, C. Zaharia, M. Bliss, E. Bill, M. Schendemann, R. Naleiro. Van interpretar fragments de "La Creació" de J. Haydn, "La donzella de neu" de N. Rimskij-Korsakov, "Madama Butterfly" de G. Puccini, "La Traviata" de G. Verdi, "Lohengrin" de R. Wagner, "Carmen" de G. Bizet i l'"Ave Maria" de F. Schubert, entre altres. També van cantar obres de G. Donizetti, W. A. Mozart, E. Grieg, J. Turina, E. Toldrà, F. Mendelssohn, J. Brahms, L. V. Beethoven, Granados, V. Bellini, G. Rossini, G. Fauré, C. Gounod i G. MahlerOrquestra del Gran Teatre del Liceu dirigida per G. Pérez BusquierDe cada obra s'ha digitalitzat un programa sencer. De la resta s'han digitalitzat les parts que són diferents

Ueber die Erziehung des Willens

vom Prorector Wagne