14 research outputs found

    Проектирование системы электроснабжения перевалопогрузочного комплекса морского порта

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    Объектом исследования является электрическая часть перевалопогрузочного комплекса ОАО «Восточный порт». Цель работы – проектирование системы электроснабжения перевалопогрузочного комплекса морского порта. В процессе исследования проводился сбор исходных данных в ходе производственной практики на объекте исследования. В результате была спроектирована схема электроснабжения от подстанции энергосистемы, до конечного электроприемника. Были выбраны кабели и провода, коммутационное оборудование. Также был произведен экономический расчет капитальных затрат на сооружение данной схемы, определены условия безопасности и гигиены труда рабочих предприятия.The object of the research is part of an electric perevalopogruzochnogo complex JSC "Vostochny Port". The purpose of the work - design of power supply system perevalopogruzochnogo seaport complex. The study was conducted to collect baseline data in the course of practical training on the subject of the study. As a result, power supply circuit has been designed from the substation grid, appliance, to the end. Cables and wires, switching equipment were chosen. There was also made economic calculation of capital costs for the construction of the scheme, identified the security conditions and hygiene of workers of the enterprise

    Mismatch negativity generation in the human 5HT2A agonist and NMDA antagonist model of psychosis

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    RATIONALE: Many studies have reported deficits of mismatch negativity (MMN) in schizophrenic patients. Pharmacological challenges with hallucinogens in healthy humans are used as models for psychotic states. Previous studies reported a significant reduction of MMN after ketamine (N-methyl-D-aspartate acid [NMDA] antagonist model) but not after psilocybin (5HT2A agonist model). OBJECTIVES: The aim of the present study was to directly compare the two models of psychosis using an intraindividual crossover design. MATERIALS AND METHODS: Fifteen healthy subjects participated in a randomized, double-blind, crossover study with a low and a high dose of the 5HT2A agonist dimethyltryptamine (DMT) and the NMDA antagonist S-ketamine. During electroencephalographic recording, the subjects were performing the AX-version of a continuous performance test (AX-CPT). A source analysis of MMN was performed on the basis of a four-source model of MMN generation. RESULTS: Nine subjects completed both experimental days with the two doses of both drugs. Overall, we found blunted MMN and performance deficits in the AX-CPT after both drugs. However, the reduction in MMN activity was overall more pronounced after S-ketamine intake, and only S-ketamine had a significant impact on the frontal source of MMN. CONCLUSIONS: The NDMA antagonist model and the 5HT2A agonist model of psychosis display distinct neurocognitive profiles. These findings are in line with the view of the two classes of hallucinogens modeling different aspects of psychosis
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