5,028 research outputs found
The well-being of British expatriate retirees in southern Europe
This article examines the personal outcomes of overseas residence in later life, by analysing some findings from the first large-scale, comparative study of the retirement of British citizens to southern Europe. Four study areas are compared: Tuscany in Italy, Malta, the Costa del Sol of Spain, and the Algarve region of Portugal. The analysis focuses on the expressed reasons for moving to and residing in the areas, the reported advantages and disadvantages, and the respondents' predictions of whether they would stay or leave in response to adverse and beneficial events.
Overall the subjects give very positive reports, but there are considerable differences among the four areas. The associations of individual variation in well-being with both a person's ‘temporal commitment’ to the area and to facets of their social integration are analysed. The onset of severe incapacity, sufficient to prevent the continued running of a home, is the event most likely to cause people to leave their adopted areas of residence
Matching the Local and Cosmic Star Formation Histories
Given the many recent advances in our understanding of the star formation
history (SFH) of the Local Group and other nearby galaxies, and in the
evolution of star formation with redshift, we present a new comparison of the
comoving space density of the star formation rate as a function of look-back
time for the Local and Distant Universe. We update the Local SFH derived from
the analysis of resolved stellar populations (``fossil records'') in individual
nearby galaxies, based on our own estimations as well as available in the
literature. While the preliminary comparison of SFHs is found to be broadly
consistent, some discrepancies still remain, including an excess of the Local
SFR density in the most recent epoch.Comment: 4 pages, slightly revised version from a contribution to 'Galaxies in
the Local Volume', Sydney, 8 - 13 July 2007, B. Koribalski and H. Jerjen, ed
Using a cognitive framework with nurses to manage stress
Nursing can be a stressful occupation with many nurses struggling to cope with stress on a day-to-day basis. Considerable evidence suggests that positive coping strategies can be an effective part of stress management education programs. This article describes the theoretical rationale for a cognitive framework for stress management that was developed as part of a well-being educational program for cancer nurses. This framework included an associated mnemonic (www.pst) to assist in the recall and utilization of positive coping strategies. The stress management framework was intended to increase nurses’ perceptions of personal control which is central to stress management. The academic coping literature is complex, jargon laden and often conceptually abstract, and may not easily be understood by a nonacademic audience. The cognitive framework described here is an evidence-based, user-friendly tool that could be used and evaluated by counsellors, educators, and researchers in different settings
Identifying the mechanisms underpinning recognition of structured sequences of action
© 2012 The Experimental Psychology SocietyWe present three experiments to identify the specific information sources that skilled participants use to make recognition judgements when presented with dynamic, structured stimuli. A group of less skilled
participants acted as controls. In all experiments, participants were presented with filmed stimuli containing structured action sequences. In a subsequent recognition phase, participants were presented with new and previously seen stimuli and were required to make judgements as to whether or not each sequence had been presented earlier (or were edited versions of earlier sequences). In Experiment 1,
skilled participants demonstrated superior sensitivity in recognition when viewing dynamic clips compared with static images and clips where the frames were presented in a nonsequential, randomized manner, implicating the importance of motion information when identifying familiar or unfamiliar sequences. In Experiment 2, we presented normal and mirror-reversed sequences in order to distort access to absolute motion information. Skilled participants demonstrated superior recognition sensitivity, but no significant differences were observed across viewing conditions, leading to the suggestion
that skilled participants are more likely to extract relative rather than absolute motion when making such judgements. In Experiment 3, we manipulated relative motion information by occluding several display
features for the duration of each film sequence. A significant decrement in performance was reported when centrally located features were occluded compared to those located in more peripheral positions.
Findings indicate that skilled participants are particularly sensitive to relative motion information when attempting to identify familiarity in dynamic, visual displays involving interaction between numerous features
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An Investigation of the Effects of Quantum Dot Nanoparticles on Photopolymer Resin for Use in PolyJet Direct 3D Printing
The addition of quantum dot (QD) nanoparticles to additive manufacturing (AM) media
provides the opportunity to create artifacts with complex geometry that also have unique optical
characteristics. However, the addition of nanoparticles can significantly alter the rheology of a
material and make it difficult to process in an AM context. In this study, quantum dots were
added to a photopolymer resin in varying mass ratios to photopolymer, and their effects on the
viscosity, surface tension, and jetting ability of the suspension were investigated. Results show
that printability was not significantly affected by the presence of quantum dots in mass
concentrations less than or equal to 0.5%. The nanosuspensions were deposited via inkjet to
demonstrate the feasibility of creating optically-unique artifacts.Mechanical Engineerin
A Nonparametric Method for the Derivation of α/β Ratios from the Effect of Fractionated Irradiations
Multifractionation isoeffect data are commonly analysed under the assumption that cell survival determines the observed tissue or tumour response, and that it follows a linear-quadratic dose dependence. The analysis is employed to derive the α/β ratios of the linear-quadratic dose dependence, and different methods have been developed for this purpose. A common method uses the so-called Fe plot. A more complex but also more rigorous method has been introduced by Lam et al. (1979). Their method, which is based on numerical optimization procedures, is generalized and somewhat simplified in the present study. Tumour-regrowth data are used to explain the nonparametric procedure which provides α/β ratios without the need to postulate analytical expressions for the relationship between cell survival and regrowth delay
Anticipation and visual search behaviour in expert soccer goalkeepers
A novel methodological approach is presented to examine the visual search behaviours employed by expert goalkeepers during simulated penalty kick situations in soccer. Expert soccer goalkeepers were classified as successful or unsuccessful based on their performance on a film-based test of anticipation skill, thereby allowing an intra-group comparison of visual search behaviour on the task. The anticipation test required participants to move a joystick in response to penalty kick situations presented on a large screen. The proportion of penalties saved was assessed as well as the frequency and time of initiation of joystick corrections. Visual search behaviour was examined using a portable eye movement registration system. The successful experts were more accurate in predicting the height and direction of the penalty kick, waited longer before initiating a response and appeared to spend longer periods of time fixating on the non-kicking leg compared with the nonsuccessful experts. © 2005 Taylor & Francis
Learning energy storage in hybrid/electric vehicles: Erasmus Mundus Master Course in Sustainable Transportation & Electrical Power Systems
The "Erasmus Mundus Master Course in Sustainable Transportation & Electrical Power Systems" is supported by three universities, located in Spain, Italy and United Kingdom, and a Polytechnic Institute in Portugal. One of the main goals is the training of qualified staff in areas related to electrical energy management, emphasizing in power systems for electric propulsion vehicles and renewable energies. Among others, the subject "Energy Storage and Recovery in Power Systems and Hybrid/Electric Vehicles" is considered a keystone in the Master. During third semester, the students who follow the technical track, have to develop small projects and tasks related to electric vehicles, battery management, power stages for battery charger and so on. This paper show the goals and the results obtained in these topics. All of these topics are partially collected in one subject, with a high practical content. The students have to learn not only the theoretical topics, but they have to elaborate a project, in a work team and use modern laboratory equipment as well. It should be noted that the students have to work and collaborate in a multicultural environment, with students and professors. This paper describes the subject methodology, and the results obtained
Trends in HIV testing and recording of HIV status in the UK primary care setting: a retrospective cohort study 1995-2005
Objectives: To provide nationally representative data on trends in HIV testing in primary care and to estimate the proportion of diagnosed HIV positive individuals known to general practitioners (GPs). Methods: We undertook a retrospective cohort study between 1995 and 2005 of all general practices contributing data to the UK General Practice Research Database (GPRD), and data on persons accessing HIV care (Survey of Prevalent HIV Infections Diagnosed). We identified all practice-registered patients where an HIV test or HIV positive status is recorded in their general practice records. HIV testing in primary care and prevalence of recorded HIV positive status in primary care were estimated. Results: Despite 11-fold increases in male testing and 19-fold increases in non-pregnant female testing between 1995 and 2005, HIV testing rates remained low in 2005 at 71.3 and 61.2 tests per 100 000 person years for males and females, respectively, peaking at 162.5 and 173.8 per 100 000 person years at 25–34 years of age. Inclusion of antenatal tests yielded a 129-fold increase in women over the 10-year period. In 2005, 50.7% of HIV positive individuals had their diagnosis recorded with a lower proportion in London (41.8%) than outside the capital (60.1%). Conclusion: HIV testing rates in primary care remain low. Normalisation of HIV testing and recording in primary care in antenatal testing has not been accompanied by a step change in wider HIV testing practice. Recording of HIV positive status by GPs remains low and GPs may be unaware of HIV-related morbidity or potential drug interactions
Distinct roles in autophagy and importance in infectivity of the two ATG4 cysteine peptidases of leishmania major
Macroautophagy in Leishmania, which is important for the cellular remodeling required during differentiation, relies upon the hydrolytic activity of two ATG4 cysteine peptidases (ATG4.1 and ATG4.2). We have investigated the individual contributions of each ATG4 to Leishmania major by generating individual gene deletion mutants (Δatg4.1 and Δatg4.2); double mutants could not be generated, indicating that ATG4 activity is required for parasite viability. Both mutants were viable as promastigotes and infected macrophages in vitro and mice, but Δatg4.2 survived poorly irrespective of infection with promastigotes or amastigotes, whereas this was the case only when promastigotes of Δatg4.1 were used. Promastigotes of Δatg4.2 but not Δatg4.1 were more susceptible than wild type promastigotes to starvation and oxidative stresses, which correlated with increased reactive oxygen species levels and oxidatively damaged proteins in the cells as well as impaired mitochondrial function. The antioxidant N-acetylcysteine reversed this phenotype, reducing both basal and induced autophagy and restoring mitochondrial function, indicating a relationship between reactive oxygen species levels and autophagy. Deletion of ATG4.2 had a more dramatic effect upon autophagy than did deletion of ATG4.1. This phenotype is consistent with a reduced efficiency in the autophagic process in Δatg4.2, possibly due to ATG4.2 having a key role in removal of ATG8 from mature autophagosomes and thus facilitating delivery to the lysosomal network. These findings show that there is a level of functional redundancy between the two ATG4s, and that ATG4.2 appears to be the more important. Moreover, the low infectivity of Δatg4.2 demonstrates that autophagy is important for the virulence of the parasite
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