1,386 research outputs found
A single-mode, high index-contrast, lead silicate glass fibre with high nonlinearity, broadband near-zero dispersion at telecommunication wavelengths
We report on the design, fabrication and characterization of a single-mode W-type lead silicate glass fibre with flattened and near-zero dispersion profile at telecom wavelengths and high nonlinearity of 820 W-1km-1 at 1.55 µm
DMRG studies of the effect of constraint release on the viscosity of polymer melts
The scaling of the viscosity of polymer melts is investigated with regard to
the molecular weight. We present a generalization of the Rubinstein-Duke model,
which takes constraint releases into account and calculate the effects on the
viscosity by the use of the Density Matrix Renormalization Group (DMRG)
algorithm. Using input from Rouse theory the rates for the constraint release
are determined in a self consistent way. We conclude that shape fluctuations of
the tube caused by constraint release are not a likely candidate for improving
Doi's crossover theory for the scaling of the polymer viscosity.Comment: 6 pages, 8 figure
The miRNA-kallikrein axis of interaction: a new dimension in the pathogenesis of prostate cancer
Kallikrein-related peptidases (KLKs) are a family of serine proteases that were shown to be useful cancer biomarkers. KLKs have been shown to be dysregulated in prostate cancer (PCa). microRNAs (miRNAs) are short RNA nucleotides that negatively regulate gene expression and have been reportedly dysregulated in PCa. We compiled a comprehensive list of 55 miRNAs that are differentially expressed in PCa from previous microarray analysis and published literature. Target prediction analyses showed that 29 of these miRNAs are predicted to target 10 KLKs. Eight of these miRNAs were predicted to target more than one KLK. Quantitative real-time (qRT)-PCR demonstrated that there was an inverse correlation pattern in the expression (normal vs. cancer) between dysregulated miRNAs and their target KLKs. In addition, we experientially validated the miRNA-KLK interaction by transfecting miR-331-3p and miR-143 into a PCa cell line. Decreased expression of targets KLK4 and KLK10, respectively, and decreased cellular growth were observed. In addition to KLKs, dysregulated miRNAs were predicted to target other genes involved in the pathogenesis of PCa. These data show that miRNAs can contribute to KLK regulation in PCa. The miRNA-KLK axis of interaction projects a new element in the pathogenesis of PCa that may have therapeutic implications
Target Fragmentation in Semi-Inclusive DIS: Fracture Functions, Cut Vertices and the OPE
We discuss semi-inclusive Deep Inelastic Scattering (DIS) in the z -> 1
limit, in particular the relationship between fracture functions, generalised
cut vertices and Green functions of the composite operators arising in the OPE.
The implications, in the spin-polarised case, for testing whether the "proton
spin" effect is target-independent are explored. Explicit calculations in
(phi^3)_6 theory are presented which are consistent with our observations.Comment: 22 pages, 25 figures, LaTeX 2e; uses graphics packag
Hybridization-induced superconductivity from the electron repulsion on a tetramer lattice having a disconnected Fermi surface
Plaquette lattices with each unit cell containing multiple atoms are good
candidates for disconnected Fermi surfaces, which are shown by Kuroki and Arita
to be favorable for spin-flucutation mediated superconductivity from electron
repulsion. Here we find an interesting example in a tetramer lattice where the
structure within each unit cell dominates the nodal structure of the gap
function. We trace its reason to the way in which a Cooper pair is formed
across the hybridized molecular orbitals, where we still end up with a T_c much
higher than usual.Comment: 4 pages, 6 figure
Influence of enhanced melt supply on upper crustal structure at a mid-ocean ridge discontinuity: A three-dimensional seismic tomographic study of 9°N East Pacific Rise
We present a three-dimensional upper crustal model of the 9°03′N overlapping spreading center (OSC) on the East Pacific Rise that assists in understanding the relationship between melt sills and upper crustal structure at a ridge discontinuity with enhanced melt supply at crustal levels. Our P wave velocity model obtained from tomographic inversion of ∼70,000 crustal first arrival travel times suggests that the geometry of extrusive emplacement are significantly different beneath the overlapping spreading limbs. Extrusive volcanic rocks above the western melt sill are inferred to be thin (∼250 m). More extensive accumulation of extrusives is inferred to the west than to the east of the western melt sill. The extrusive layer inferred above the eastern melt sill thickens from ∼350 (at the neovolcanic axis) to 550 m (to the west of the melt sill). Volcanic construction is likely to be significant in the formation of ridge crest morphology at the OSC, particularly at the tip of the eastern limb. On the basis of our interpretation of the velocity model, we propose that enhanced magma supply at crustal levels at the OSC may provide an effective mechanism for the migration of ridge discontinuities. This “dynamic magma supply model” may explain the commonly observed nonsteady migration pattern of ridge discontinuities by attributing this to the temporal fluctuations in melt availability to the overlapping spreading limbs
Superconductivity in quantum-dot superlattices composed of quantum wire networks
Based on calculations using the local density approximation, we propose
quantum wire networks with square and plaquette type lattice structures that
form quantum dot superlattices. These artificial structures are well described
by the Hubbard model. Numerical analysis reveals a superconducting ground state
with transition temperatures of up to 90 mK for the plaquette, which is
more than double the value of 40 mK for the square lattice type and is
sufficiently high to allow for the experimental observation of
superconductivity.Comment: 10 pages, 4 figure
Optical realization of universal quantum cloning
Beyond the no-cloning theorem, the universal symmetric quantum cloning
machine was first addressed by Buzek and Hillery. Here, we realized the
one-to-two qubits Buzek-Hillery cloning machine with linear optical devices.
This method relies on the representation of several qubits by a single photon.
We showed that, the fidelities between the two output qubits and the original
qubit are both 5/6 (which proved to be the optimal fidelity of one-to-two
qubits universal cloner) for arbitrary input pure states.Comment: 5 Pages, 2 Figure
Enhancing gravitational wave astronomy with galaxy catalogues
Joint gravitational wave (GW) and electromagnetic (EM) observations, as a key
research direction in multi-messenger astronomy, will provide deep insight into
the astrophysics of a vast range of astronomical phenomena. Uncertainties in
the source sky location estimate from gravitational wave observations mean
follow-up observatories must scan large portions of the sky for a potential
companion signal. A general frame of joint GW-EM observations is presented by a
multi-messenger observational triangle. Using a Bayesian approach to
multi-messenger astronomy, we investigate the use of galaxy catalogue and host
galaxy information to reduce the sky region over which follow-up observatories
must scan, as well as study its use for improving the inclination angle
estimates for coalescing binary compact objects. We demonstrate our method
using a simulated neutron stars inspiral signal injected into simulated
Advanced detectors noise and estimate the injected signal sky location and
inclination angle using the Gravitational Wave Galaxy Catalogue. In this case
study, the top three candidates in rank have , and posterior
probability of being the host galaxy, receptively. The standard deviation of
cosine inclination angle (0.001) of the neutron stars binary using
gravitational wave-galaxy information is much smaller than that (0.02) using
only gravitational wave posterior samples.Comment: Proceedings of the Sant Cugat Forum on Astrophysics. 2014 Session on
'Gravitational Wave Astrophysics
A step towards testing general relativity using weak gravitational lensing and redshift surveys
Using the linear theory of perturbations in General Relativity, we express a
set of consistency relations that can be observationally tested with current
and future large scale structure surveys. We then outline a stringent
model-independent program to test gravity on cosmological scales. We illustrate
the feasibility of such a program by jointly using several observables like
peculiar velocities, galaxy clustering and weak gravitational lensing. After
addressing possible observational or astrophysical caveats like galaxy bias and
redshift uncertainties, we forecast in particular how well one can predict the
lensing signal from a cosmic shear survey using an over-lapping galaxy survey.
We finally discuss the specific physics probed this way and illustrate how
gravity models would fail such a test.Comment: 12 pages, 10 figure
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