662 research outputs found
Constant curvature solutions of Grassmannian sigma models: (1) Holomorphic solutions
We present a general formula for the Gaussian curvature of curved holomorphic
2-spheres in Grassmannian manifolds G(m, n). We then show how to construct such
solutions with constant curvature. We also make some relevant conjectures for
the admissible constant curvatures in G(m, n) and give some explicit
expressions, in particular, for G(2, 4) and G(2, 5).Comment: 14 page
Quantum Locality
It is argued that while quantum mechanics contains nonlocal or entangled
states, the instantaneous or nonlocal influences sometimes thought to be
present due to violations of Bell inequalities in fact arise from mistaken
attempts to apply classical concepts and introduce probabilities in a manner
inconsistent with the Hilbert space structure of standard quantum mechanics.
Instead, Einstein locality is a valid quantum principle: objective properties
of individual quantum systems do not change when something is done to another
noninteracting system. There is no reason to suspect any conflict between
quantum theory and special relativity.Comment: Introduction has been revised, references added, minor corrections
elsewhere. To appear in Foundations of Physic
Gene expression identifies metabolic and functional differences between intramuscular and subcutaneous adipocytes in cattle
Background
This study used a genome-wide screen of gene expression to better understand the metabolic and functional differences between commercially valuable intramuscular fat (IMF) and commercially wasteful subcutaneous (SC) fat depots in Bos taurus beef cattle.
Results
We confirmed many findings previously made at the biochemical level and made new discoveries. The fundamental lipogenic machinery, such as ACACA and FASN encoding the rate limiting Acetyl CoA carboxylase and Fatty Acid synthase were expressed at 1.6–1.8 fold lower levels in IMF, consistent with previous findings. The FA elongation pathway including the rate limiting ELOVL6 was also coordinately downregulated in IMF compared to SC as expected. A 2-fold lower expression in IMF of ACSS2 encoding Acetyl Coenzyme A synthetase is consistent with utilisation of less acetate for lipogenesis in IMF compared to SC as previously determined using radioisotope incorporation. Reduced saturation of fat in the SC depot is reflected by 2.4 fold higher expression of the SCD gene encoding the Δ9 desaturase enzyme. Surprisingly, CH25H encoding the cholesterol 25 hydroxylase enzyme was ~ 36 fold upregulated in IMF compared to SC. Moreover, its expression in whole muscle tissue appears representative of the proportional representation of bovine marbling adipocytes. This suite of observations prompted quantification of a set of oxysterols (oxidised forms of cholesterol) in the plasma of 8 cattle exhibiting varying IMF. Using Liquid Chromatography-Mass Spectrometry (LC-MS) we found the levels of several oxysterols were significantly associated with multiple marbling measurements across the musculature, but (with just one exception) no other carcass phenotypes.
Conclusions
These data build on our molecular understanding of ruminant fat depot biology and suggest oxysterols represent a promising circulating biomarker for cattle marbling
Updated tests of scaling and universality for the spin-spin correlations in the 2D and 3D spin-S Ising models using high-temperature expansions
We have extended, from order 12 through order 25, the high-temperature series
expansions (in zero magnetic field) for the spin-spin correlations of the
spin-S Ising models on the square, simple-cubic and body-centered-cubic
lattices. On the basis of this large set of data, we confirm accurately the
validity of the scaling and universality hypotheses by resuming several tests
which involve the correlation function, its moments and the exponential or the
second-moment correlation-lengths.Comment: 21 pages, 8 figure
The Quantum Mechanical Arrows of Time
The familiar textbook quantum mechanics of laboratory measurements
incorporates a quantum mechanical arrow of time --- the direction in time in
which state vector reduction operates. This arrow is usually assumed to
coincide with the direction of the thermodynamic arrow of the quasiclassical
realm of everyday experience. But in the more general context of cosmology we
seek an explanation of all observed arrows, and the relations between them, in
terms of the conditions that specify our particular universe. This paper
investigates quantum mechanical and thermodynamic arrows in a time-neutral
formulation of quantum mechanics for a number of model cosmologies in fixed
background spacetimes. We find that a general universe may not have well
defined arrows of either kind. When arrows are emergent they need not point in
the same direction over the whole of spacetime. Rather they may be local,
pointing in different directions in different spacetime regions. Local arrows
can therefore be consistent with global time symmetry.Comment: 9 pages, 4 figures, revtex4, typos correcte
An emerging viral pathogen truncates population age structure in a European amphibian and may reduce population viability
Infectious diseases can alter the demography of their host populations, reducing their viability even in the absence of mass mortality. Amphibians are the most threatened group of vertebrates globally, and emerging infectious diseases play a large role in their continued population declines. Viruses belonging to the genus Ranavirus are responsible for one of the deadliest and most widespread of these diseases. To date, no work has used individual level data to investigate how ranaviruses affect population demographic structure. We used skeletochronology and morphology to evaluate the impact of ranaviruses on the age structure of populations of the European common frog (Rana temporaria) in the UK. We compared ecologically similar populations that differed most notably in their historical presence or absence of ranavirosis (the acute syndrome caused by ranavirus infection). Our results suggest that ranavirosis may truncate the age structure of R. temporaria populations. One potential explanation for such a shift might be increased adult mortality and subsequent shifts in the life history of younger age classes that increase reproductive output earlier in life. Additionally, we constructed population projection models which indicated that such increased adult mortality could heighten the vulnerability of frog populations to stochastic environmental challenges
A cognitive framework for the categorisation of auditory objects in urban soundscapes
Categorisation is a fundamental cognitive process that plays a central role in
everyday behaviour and action. Whereas previous studies have investigated the
categorisation of isolated everyday sounds, this paper presents an experiment to
investigate the cognitive categorisation of everyday sounds within their original
context. A group of eighteen expert and non-expert listeners took part in a free
sorting task using 110 sounds identified within ambisonic reproductions of urban
soundscapes. The participants were asked to sort the objects into groups of
sounds that served a similar purpose in the overall perception of the soundscape.
Following this, the participants were asked to provide descriptive labels for the
groups they had formed. The results were analysed using hierarchical agglomerative
clustering and non-metric multidimensional scaling (MDS) to explore
both the structure and dimensionality of the data. The resulting hierarchical
clustering of objects show three top level categories relating to transient sounds,
continuous sounds, and speech and vocalisations. Sub-categories were identified
in each of the top level categories which included harmonic and non-harmonic
continuous sounds, clear speech, unintelligible speech, vocalisations, transient
sounds that indicate actions, and non-salient transient sounds. The first two
dimensions revealed by the MDS analysis relate to temporal extent and intelligibility
respectively. Interpretation of the third dimension is less clear, but may be related to harmonic content
Low Q^2 Jet Production at HERA and Virtual Photon Structure
The transition between photoproduction and deep-inelastic scattering is
investigated in jet production at the HERA ep collider, using data collected by
the H1 experiment. Measurements of the differential inclusive jet
cross-sections dsigep/dEt* and dsigmep/deta*, where Et* and eta* are the
transverse energy and the pseudorapidity of the jets in the virtual
photon-proton centre of mass frame, are presented for 0 < Q2 < 49 GeV2 and 0.3
< y < 0.6. The interpretation of the results in terms of the structure of the
virtual photon is discussed. The data are best described by QCD calculations
which include a partonic structure of the virtual photon that evolves with Q2.Comment: 20 pages, 5 Figure
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