13,389 research outputs found

    Air quality monitoring for vulnerable groups in residential environments using a multiple hazard gas detector

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    © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This paper presents a smart “e-nose” device to monitor indoor hazardous air. Indoor hazardous odor is a threat for seniors, infants, children, pregnant women, disabled residents, and patients. To overcome the limitations of using existing non-intelligent, slow-responding, deficient gas sensors, we propose a novel artificial-intelligent-based multiple hazard gas detector (MHGD) system that is mounted on a motor vehicle-based robot which can be remotely controlled. First, we optimized the sensor array for the classification of three hazardous gases, including cigarette smoke, inflammable ethanol, and off-flavor from spoiled food, using an e-nose with a mixing chamber. The mixing chamber can prevent the impact of environmental changes. We compared the classification results of all combinations of sensors, and selected the one with the highest accuracy (98.88%) as the optimal sensor array for the MHGD. The optimal sensor array was then mounted on the MHGD to detect and classify the target gases without a mixing chamber but in a controlled environment. Finally, we tested the MHGD under these conditions, and achieved an acceptable accuracy (70.00%)

    The two-point resistance of a resistor network: A new formulation and application to the cobweb network

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    We consider the problem of two-point resistance in a resistor network previously studied by one of us [F. Y. Wu, J. Phys. A {\bf 37}, 6653 (2004)]. By formulating the problem differently, we obtain a new expression for the two-point resistance between two arbitrary nodes which is simpler and can be easier to use in practice. We apply the new formulation to the cobweb resistor network to obtain the resistance between two nodes in the network. Particularly, our results prove a recently proposed conjecture on the resistance between the center node and a node on the network boundary. Our analysis also solves the spanning tree problem on the cobweb network.Comment: 14 pages, 1 figure, adding one references and discussions of special case

    Retrovirus Integration Database (RID): A public database for retroviral insertion sites into host genomes

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    The NCI Retrovirus Integration Database is a MySql-based relational database created for storing and retrieving comprehensive information about retroviral integration sites, primarily, but not exclusively, HIV-1. The database is accessible to the public for submission or extraction of data originating from experiments aimed at collecting information related to retroviral integration sites including: the site of integration into the host genome, the virus family and subtype, the origin of the sample, gene exons/introns associated with integration, and proviral orientation. Information about the references from which the data were collected is also stored in the database. Tools are built into the website that can be used to map the integration sites to UCSC genome browser, to plot the integration site patterns on a chromosome, and to display provirus LTRs in their inserted genome sequence. The website is robust, user friendly, and allows users to query the database and analyze the data dynamically. Availability: https://rid.ncifcrf.gov; or http://home.ncifcrf.gov/hivdrp/resources.htm

    A rigorous analysis of high order electromagnetic invisibility cloaks

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    There is currently a great deal of interest in the invisibility cloaks recently proposed by Pendry et al. that are based in the transformation approach. They obtained their results using first order transformations. In recent papers Hendi et al. and Cai et al. considered invisibility cloaks with high order transformations. In this paper we study high order electromagnetic invisibility cloaks in transformation media obtained by high order transformations from general anisotropic media. We consider the case where there is a finite number of spherical cloaks located in different points in space. We prove that for any incident plane wave, at any frequency, the scattered wave is identically zero. We also consider the scattering of finite energy wave packets. We prove that the scattering matrix is the identity, i.e., that for any incoming wave packet the outgoing wave packet is the same as the incoming one. This proves that the invisibility cloaks can not be detected in any scattering experiment with electromagnetic waves in high order transformation media, and in particular in the first order transformation media of Pendry et al. We also prove that the high order invisibility cloaks, as well as the first order ones, cloak passive and active devices. The cloaked objects completely decouple from the exterior. Actually, the cloaking outside is independent of what is inside the cloaked objects. The electromagnetic waves inside the cloaked objects can not leave the concealed regions and viceversa, the electromagnetic waves outside the cloaked objects can not go inside the concealed regions. As we prove our results for media that are obtained by transformation from general anisotropic materials, we prove that it is possible to cloak objects inside general crystals.Comment: The final version is now published in Journal of Physics A: Mathematical and Theoretical, vol 41 (2008) 065207 (21 pp). Included in IOP-Selec

    In situ revelation of a zinc-blende InN wetting layer during Stranski-Krastanov growth on GaN(0001) by molecular-beam epitaxy

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    Indium nitride (InN) exists in two different structural phases, the equilibrium wurtzite (w) and the metastable zinc-blende (zb) phases. It is of scientific interest and practical relevance to examine the crystal structure of the epifilms during growth. In this paper, we use Patterson function inversion of low-energy electron diffraction I-V curves to reveal the preferential formation of zinc-blende InN wetting layer during the Stranski-Krastanov growth on GaN(0001). For three-dimensional islands nucleated afterwards on top of the wetting layer and for thick InN films, the equilibrium wurtzite structure is observed instead. This in situ revelation of the InN lattice structure is confirmed by ex situ transmission electron microscopy studies. Finally, the formation of zb-InN layer on w-GaN is explained in terms of the strain in the system. © 2005 The American Physical Society.published_or_final_versio

    Nuclear spin driven quantum relaxation in LiY_0.998Ho_0.002F_4

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    Staircase hysteresis loops of the magnetization of a LiY_0.998Ho_0.002F_4 single crystal are observed at subkelvin temperatures and low field sweep rates. This behavior results from quantum dynamics at avoided level crossings of the energy spectrum of single Ho^{3+} ions in the presence of hyperfine interactions. Enhanced quantum relaxation in constant transverse fields allows the study of the relative magnitude of tunnel splittings. At faster sweep rates, non-equilibrated spin-phonon and spin-spin transitions, mediated by weak dipolar interactions, lead to magnetization oscillations and additional steps.Comment: 5 pages, 5 eps figures, using RevTe

    RNA polymerase II stalling promotes nucleosome occlusion and pTEFb recruitment to drive immortalization by Epstein-Barr virus

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    Epstein-Barr virus (EBV) immortalizes resting B-cells and is a key etiologic agent in the development of numerous cancers. The essential EBV-encoded protein EBNA 2 activates the viral C promoter (Cp) producing a message of ~120 kb that is differentially spliced to encode all EBNAs required for immortalization. We have previously shown that EBNA 2-activated transcription is dependent on the activity of the RNA polymerase II (pol II) C-terminal domain (CTD) kinase pTEFb (CDK9/cyclin T1). We now demonstrate that Cp, in contrast to two shorter EBNA 2-activated viral genes (LMP 1 and 2A), displays high levels of promoter-proximally stalled pol II despite being constitutively active. Consistent with pol II stalling, we detect considerable pausing complex (NELF/DSIF) association with Cp. Significantly, we observe substantial Cp-specific pTEFb recruitment that stimulates high-level pol II CTD serine 2 phosphorylation at distal regions (up to +75 kb), promoting elongation. We reveal that Cp-specific pol II accumulation is directed by DNA sequences unfavourable for nucleosome assembly that increase TBP access and pol II recruitment. Stalled pol II then maintains Cp nucleosome depletion. Our data indicate that pTEFb is recruited to Cp by the bromodomain protein Brd4, with polymerase stalling facilitating stable association of pTEFb. The Brd4 inhibitor JQ1 and the pTEFb inhibitors DRB and Flavopiridol significantly reduce Cp, but not LMP1 transcript production indicating that Brd4 and pTEFb are required for Cp transcription. Taken together our data indicate that pol II stalling at Cp promotes transcription of essential immortalizing genes during EBV infection by (i) preventing promoter-proximal nucleosome assembly and ii) necessitating the recruitment of pTEFb thereby maintaining serine 2 CTD phosphorylation at distal regions

    Doping Fe-based diamond tool matrix composites with a rare-earth element

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    The paper presents the experiments on adding rare-earth element cerium to diamond matrix composites. Based on the doping of rare earth in metal powders including tungsten carbide, a small amount of nickel, iron entirely replacing cobalt in diamond matrix and the process route of rare earth doping is indicated. The performance of matrix composites with and without rare-earth elements has been assessed. The results obtained show that the flexural strength, the hardness, and the impact ductility of matrix composites with rare-earth elements have been improved. The flexural strength and the impact ductility increased correspondently by 10—62 % and about 5 %, as compared to composites free of rare-earth elements. Rare-earth diamond tool matrix composites where Co was replaced with Fe, which provides a good practical service performanc, and a low price, have been successfully studied, corresponding diamond bits and saw blades have been manufactured

    Investigation of profile shifting and subpulse movement in PSR J0344-0901 with FAST

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    We report two phenomena detected in PSR J0344-0901 from two observations conducted at frequency centered at 1.25 GHz using the Five-hundred-meter Aperture Spherical radio Telescope (FAST). The first phenomenon manifests as shifting in the pulse emission to later longitudinal phases and then gradually returns to its original location. The event lasts for about 216 pulse periods, with an average shift of about 0.70.7^\circ measured at the peak of the integrated profile. Changes in the polarization position angle (PPA) are detected around the trailing edge of the profile, together with an increase in the profile width. The second phenomenon is characterized by the apparent movement of subpulses, which results in different subpulse track patterns across the profile window. For the first time in this pulsar, we identify four emission modes, each with unique subpulse movement, and determine the pattern periods for three of the emission modes. Pulse nulling was not detected. Modeling of the changes in the PPA using the rotating vector model gives an inclination angle of 75.12±3.8075.12^\circ \pm 3.80^\circ and an impact parameter of 3.17±5.32-3.17^\circ \pm 5.32^\circ for this pulsar. We speculate that the subpulse movement may be related to the shifting of the pulse emission
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