Vertex reconstruction framework and its implementation for CMS

The class framework developed for vertex reconstruction in CMS is described. We emphasize how we proceed to develop a flexible, efficient and reliable piece of reconstruction software. We describe the decomposition of the algorithms into logical parts, the mathematical toolkit, and the way vertex reconstruction integrates into the CMS reconstruction project ORCA. We discuss the tools that we have developed for algorithm evaluation and optimization and for code release.Comment: Talk from the 2003 Computing in High Energy and Nuclear Physics (CHEP03), La Jolla, Ca, USA, March 2003, 4 pages, LaTeX, no figures. PSN TULT01

New vertex reconstruction algorithms for CMS

The reconstruction of interaction vertices can be decomposed into a pattern recognition problem (``vertex finding'') and a statistical problem (``vertex fitting''). We briefly review classical methods. We introduce novel approaches and motivate them in the framework of high-luminosity experiments like at the LHC. We then show comparisons with the classical methods in relevant physics channelsComment: Talk from the 2003 Computing in High Energy and Nuclear Physics (CHEP03), La Jolla, Ca, USA, March 2003, 5 pages, LaTeX, 3 eps figures. PSN TULT01

Fine Structure of the Oocyst Walls of \u3ci\u3eIsospora serini\u3c/i\u3e and \u3ci\u3eIsospora canaria\u3c/i\u3e and Excystation of \u3ci\u3eIsospora serini\u3c/i\u3e From the Canary, \u3ci\u3eSerinus canarius\u3c/i\u3e L.

Oocysts of Isospora serini and Isospora canaria, from the canary Serinus canarius, were broken, added to a cell suspension, fixed in Karnovsky\u27s fluid, and studied in the electron microscope. The oocyst wall of each species had an electron- lucent inner layer, a more osmiophilic middle layer and an outer layer of electron-lucent (I. serini) or electron-dense material interspersed with some electron-lucent material (I. canaria). A few, relatively large lipid-like bodies were present in the outer or middle layer of the oocyst wall of I. canaria. As many as 9 membranes were present in the oocyst wall of I. canaria and 3 in that of I. serini. When exposed to a trypsin-sodium taurocholate fluid, sporozoites of I. serini excysted from 5-month-old sporocysts in vitro, but not from sporocysts stored for more than 6 months. No excystation occurred in l5-month-old I. canaria sporocysts. Similarities and differences in excystation between I. serini and other Isospora, Eimeria, and Sarcocystis species are discussed

A Look-Ahead Feature - Sow Stalls for Indiviudal Feeding

Overfeeding sows and gilts during gestation is a common mismanagement practice. Here\u27s how concrete stalls were built for individual feeding to assure a minimum, but adequate, amount of feed for each animal

IFN-γ and TNF-α synergize to inhibit CTGF expression in human lung endothelial cells.

Connective tissue growth factor (CTGF/CCN2) is an angiogenetic and profibrotic factor, acting downstream of TGF-β, involved in both airway- and vascular remodeling. While the T-helper 1 (Th1) cytokine interferon-gamma (IFN-γ) is well characterized as immune-modulatory and anti-fibrotic cytokine, the role of IFN-γ in lung endothelial cells (LEC) is less defined. Tumour necrosis factor alpha (TNF-α) is another mediator that drives vascular remodeling in inflammation by influencing CTGF expression. In the present study we investigated the influence of IFN-γ and TNF-α on CTGF expression in human LEC (HPMEC-ST1.6R) and the effect of CTGF knock down on human LEC. IFN-γ and TNF-α down-regulated CTGF in human LEC at the promoter-, transcriptional- and translational-level in a dose- and time-dependent manner. The inhibitory effect of IFN-γ on CTGF-expression could be almost completely compensated by the Jak inhibitor AG-490, showing the involvement of the Jak-Stat signaling pathway. Besides the inhibitory effect of IFN-γ and TNF-α alone on CTGF expression and LEC proliferation, these cytokines had an additive inhibitory effect on proliferation as well as on CTGF expression when administered together. To study the functional role of CTGF in LEC, endogenous CTGF expression was down-regulated by a lentiviral system. CTGF silencing in LEC by transduction of CTGF shRNA reduced cell proliferation, but did not influence the anti-proliferative effect of IFN-γ and TNF-α. In conclusion, our data demonstrated that CTGF was negatively regulated by IFN-γ in LEC in a Jak/Stat signaling pathway-dependent manner. In addition, an additive effect of IFN-γ and TNF-α on inhibition of CTGF expression and cell proliferation could be found. The inverse correlation between IFN-γ and CTGF expression in LEC could mean that screwing the Th2 response to a Th1 response with an additional IFN-γ production might be beneficial to avoid airway remodeling in asthma

An off-shell I.R. regularization strategy in the analysis of collinear divergences

We present a method for the analysis of singularities of Feynman amplitudes based on the Speer sector decomposition of the Schwinger parametric integrals combined with the Mellin-Barnes transform. The sector decomposition method is described in some details. We suggest the idea of applying the method to the analysis of collinear singularities in inclusive QCD cross sections in the mass-less limit regularizing the forward amplitudes by an off-shell choice of the initial particle momenta. It is shown how the suggested strategy works in the well known case of the one loop corrections to Deep Inelastic Scattering.Comment: 25 pages, 3 figure

Pathways to Empowerment in Substance Abuse Prevention: Citizen Participation, Sense of Community, and Police Responsiveness in an Urban U.S. Setting

Community-based substance abuse prevention initiatives often rely on the empowerment of community residents. Few studies, however, have examined predictors of empowerment in substance abuse prevention contexts. This study tested a path model that included two environment-related variables (i.e., residents’ awareness of community substance abuse problems and perceived incivilities in their community), two variables representing residents’ perceptions of their community (i.e., sense of community and perceived police responsiveness to drug crime) and citizen participation as predictors of the intrapersonal component of psychological empowerment. The model was found to provide a good fit to the data from a random sample of urban residents (n=283) who participated in an evaluation of a National Institute of Justice community policing initiative in the Southwestern United States. Findings suggest that empowerment-based interventions aimed at preventing substance abuse and its related harmful consequences should incorporate activities that specifically address sense of community and police responsiveness to drug crime. Limitations and directions for future research are discussed

Pathways to Empowerment in Substance Abuse Prevention: Citizen Participation, Sense of Community, and Police Responsiveness in an Urban U.S. Setting

Community-based substance abuse prevention initiatives often rely on the empowerment of community residents. Few studies, however, have examined predictors of empowerment in substance abuse prevention contexts. This study tested a path model that included two environment-related variables (i.e., residents’ awareness of community substance abuse problems and perceived incivilities in their community), two variables representing residents’ perceptions of their community (i.e., sense of community and perceived police responsiveness to drug crime) and citizen participation as predictors of the intrapersonal component of psychological empowerment. The model was found to provide a good fit to the data from a random sample of urban residents (n=283) who participated in an evaluation of a National Institute of Justice community policing initiative in the Southwestern United States. Findings suggest that empowerment-based interventions aimed at preventing substance abuse and its related harmful consequences should incorporate activities that specifically address sense of community and police responsiveness to drug crime. Limitations and directions for future research are discussed