Sequential and co-tunneling behavior in the temperature-dependent thermopower of few-electron quantum dots

We have studied the temperature dependent thermopower of gate-defined, lateral quantum dots in the Coulomb blockade regime using an electron heating technique. The line shape of the thermopower oscillations depends strongly on the contributing tunneling processes. Between 1.5 K and 40 mK a crossover from a pure sawtooth- to an intermitted sawtooth-like line shape is observed. The latter is attributed to the increasing dominance of cotunneling processes in the Coulomb blockade regime at low temperatures.Comment: 4 pages, 4 figures, submitted to Phys. Rev.

Thermopower of a Kondo-correlated quantum dot

The thermopower of a Kondo-correlated gate-defined quantum dot is studied using a current heating technique. In the presence of spin correlations the thermopower shows a clear deviation from the semiclassical Mott relation between thermopower and conductivity. The strong thermopower signal indicates a significant asymmetry in the spectral density of states of the Kondo resonance with respect to the Fermi energies of the reservoirs. The observed behavior can be explained within the framework of an Anderson-impurity model. Keywords: Thermoelectric and thermomagnetic effects, Coulomb blockade, single electron tunneling, Kondo-effect PACS Numbers: 72.20.Pa, 73.23.HkComment: 4 pages, 4 figures, revised version, changed figure

Measuring Temperature Gradients over Nanometer Length Scales

When a quantum dot is subjected to a thermal gradient, the temperature of electrons entering the dot can be determined from the dot's thermocurrent if the conductance spectrum and background temperature are known. We demonstrate this technique by measuring the temperature difference across a 15 nm quantum dot embedded in a nanowire. This technique can be used when the dot's energy states are separated by many kT and will enable future quantitative investigations of electron-phonon interaction, nonlinear thermoelectric effects, and the effciency of thermoelectric energy conversion in quantum dots.Comment: 6 pages, 5 figure

Characteristic molecular properties of one-electron double quantum rings under magnetic fields

The molecular states of conduction electrons in laterally coupled quantum rings are investigated theoretically. The states are shown to have a distinct magnetic field dependence, which gives rise to periodic fluctuations of the tunnel splitting and ring angular momentum in the vicinity of the ground state crossings. The origin of these effects can be traced back to the Aharonov-Bohm oscillations of the energy levels, along with the quantum mechanical tunneling between the rings. We propose a setup using double quantum rings which shows that Aharonov-Bohm effects can be observed even if the net magnetic flux trapped by the carriers is zero.Comment: 16 pages (iopart format), 10 figures, accepted in J.Phys.Cond.Mat

Ultrafast optical control of entanglement between two quantum dot spins

The interaction between two quantum bits enables entanglement, the two-particle correlations that are at the heart of quantum information science. In semiconductor quantum dots much work has focused on demonstrating single spin qubit control using optical techniques. However, optical control of entanglement of two spin qubits remains a major challenge for scaling from a single qubit to a full-fledged quantum information platform. Here, we combine advances in vertically-stacked quantum dots with ultrafast laser techniques to achieve optical control of the entangled state of two electron spins. Each electron is in a separate InAs quantum dot, and the spins interact through tunneling, where the tunneling rate determines how rapidly entangling operations can be performed. The two-qubit gate speeds achieved here are over an order of magnitude faster than in other systems. These results demonstrate the viability and advantages of optically controlled quantum dot spins for multi-qubit systems.Comment: 24 pages, 5 figure

Harmonic Sums and Mellin Transforms up to two-loop Order

A systematic study is performed on the finite harmonic sums up to level four. These sums form the general basis for the Mellin transforms of all individual functions $f_i(x)$ of the momentum fraction $x$ emerging in the quantities of massless QED and QCD up to two--loop order, as the unpolarized and polarized splitting functions, coefficient functions, and hard scattering cross sections for space and time-like momentum transfer. The finite harmonic sums are calculated explicitly in the linear representation. Algebraic relations connecting these sums are derived to obtain representations based on a reduced set of basic functions. The Mellin transforms of all the corresponding Nielsen functions are calculated.Comment: 44 pages Latex, contract number adde

Rectification of electronic heat current by a hybrid thermal diode

We report the realization of an ultra-efficient low-temperature hybrid heat current rectifier, thermal counterpart of the well-known electric diode. Our design is based on a tunnel junction between two different elements: a normal metal and a superconducting island. Electronic heat current asymmetry in the structure arises from large mismatch between the thermal properties of these two. We demonstrate experimentally temperature differences exceeding $60$ mK between the forward and reverse thermal bias configurations. Our device offers a remarkably large heat rectification ratio up to $\sim 140$ and allows its prompt implementation in true solid-state thermal nanocircuits and general-purpose electronic applications requiring energy harvesting or thermal management and isolation at the nanoscale.Comment: 8 pages, 6 color figure

Discovery and Physical Characterization of a Large Scattered Disk Object at 92 au

We report the observation and physical characterization of the possible dwarf planet 2014. UZ224 ("DeeDee"), a dynamically detached trans-Neptunian object discovered at 92 au. This object is currently the second-most distant known trans-Neptunian object with reported orbital elements, surpassed in distance only by the dwarf planet Eris. The object was discovered with an r-band magnitude of 23.0 in data collected by the Dark Energy Survey between 2014 and 2016. Its 1140 year orbit has (a, e, i)=(109 au, 0.65, 26 degrees.8). It will reach its perihelion distance of 38 au in the year 2142. Integrations of its orbit show it to be dynamically stable on Gyr timescales, with only weak interactions with Neptune. We have performed follow-up observations with ALMA, using 3 hr of on-source integration time to measure the object's thermal emission in the Rayleigh-Jeans tail. The signal is detected at 7 sigma significance, from which we determine a V-band albedo of 13.1(-2.4)(+3.3)(stat)sys percent and a diameter of 635(-61)(+57)(stat)(-39)(+32)(sys) km assuming a spherical body with uniform surface properties

Discovery and physical characterization of a large scattered disk object at 92 au

We report the observation and physical characterization of the possible dwarf planet 2014 UZ224 ("DeeDee"), a dynamically detached trans-Neptunian object discovered at 92 au. This object is currently the second-most distant known trans-Neptunian object with reported orbital elements, surpassed in distance only by the dwarf planet Eris. The object was discovered with an r-band magnitude of 23.0 in data collected by the Dark Energy Survey between 2014 and 2016. Its 1140 year orbit has (a,e,i)=(109 au,0.65,26.8. It will reach its perihelion distance of 38 au in the year 2142. Integrations of its orbit show it to be dynamically stable on Gyr timescales, with only weak interactions with Neptune. We have performed follow-up observations with ALMA, using 3 hr of on-source integration time to measure the object's thermal emission in the Rayleigh–Jeans tail. The signal is detected at 7σ significance, from which we determine a V-band albedo of 13.1 -2.4+3.3(stat) -1.4+2.0(sys) percent and a diameter of 635 -61+57(stat) -39+32(sys) km, assuming a spherical body with uniform surface properties

Inhibitors of dihydroorotate dehydrogenase synergize with the broad antiviral activity of 4′-fluorouridine

RNA viruses present a constant threat to human health, often with limited options for vaccination or therapy. Notable examples include influenza viruses and coronaviruses, which have pandemic potential. Filo- and henipaviruses cause more limited outbreaks, but with high case fatality rates. All RNA viruses rely on the activity of a virus-encoded RNA-dependent RNA polymerase (RdRp). An antiviral nucleoside analogue, 4′-Fluorouridine (4′-FlU), targets RdRp and diminishes the replication of several RNA viruses, including influenza A virus and SARS-CoV-2, through incorporation into nascent viral RNA and delayed chain termination. However, the effective concentration of 4′-FlU varied among different viruses, raising the need to fortify its efficacy. Here we show that inhibitors of dihydroorotate dehydrogenase (DHODH), an enzyme essential for pyrimidine biosynthesis, can synergistically enhance the antiviral effect of 4′-FlU against influenza A viruses, SARS-CoV-2, henipaviruses, and Ebola virus. Even 4′-FlU-resistant mutant influenza A virus was re-sensitized towards 4′-FlU by DHODH inhibition. The addition of uridine rescued influenza A virus replication, strongly suggesting uridine depletion as a mechanism of this synergy. 4′-FlU was also highly effective against SARS-CoV-2 in a hamster model of COVID. We propose that the impairment of endogenous uridine synthesis by DHODH inhibition enhances the incorporation of 4′-FlU into viral RNAs. This strategy may be broadly applicable to enhance the efficacy of pyrimidine nucleoside analogues for antiviral therapy