An 8-cm ion thruster characterization

The performance of the Ion Auxiliary Propulsion System (IAPS) thruster was increased to thrust T = 32 mN, specific impulse I sub sp = 4062 s, and thrust-to-power ratio T/P = 33 mN/kW. This performance was obtained by increasing the discharge power, accelerating voltage, propellant flow rate, and chamber magnetic field. Adding a plenum and main vaporizer for propellant distribution was the only major change required in the thruster. The modified thruster characterization is presented. A cathode magnet assembly did not improve performance. A simplified power processing unit was designed and evaluated. This unit decreased the parts count of the IAPS power processing unit by a factor of ten

The generic mapping tools version 6

The Generic Mapping Tools (GMT) software is ubiquitous in the Earth and ocean sciences. As a cross-platform tool producing high-quality maps and figures, it is used by tens of thousands of scientists around the world. The basic syntax of GMT scripts has evolved very slowly since the 1990s, despite the fact that GMT is generally perceived to have a steep learning curve with many pitfalls for beginners and experienced users alike. Reducing these pitfalls means changing the interface, which would break compatibility with thousands of existing scripts. With the latest GMT version 6, we solve this conundrum by introducing a new "modern mode" to complement the interface used in previous versions, which GMT 6 now calls "classic mode." GMT 6 defaults to classic mode and thus is a recommended upgrade for all GMT 5 users. Nonetheless, new users should take advantage of modern mode to make shorter scripts, quickly access commonly used global data sets, and take full advantage of the new tools to draw subplots, place insets, and create animations.Funding Agency National Science Foundation (NSF) Appeared in article as U.S. National Science Foundation MSU Geological Sciences Endowmentinfo:eu-repo/semantics/publishedVersio

Field-Induced Magnetic Order in Quantum Spin Liquids

We study magnetic field-induced three-dimensional ordering transitions in low-dimensional quantum spin liquids, such as weakly coupled, antiferromagnetic spin-1/2 Heisenberg dimers and ladders. Using stochastic series expansion quantum Monte Carlo simulations, thermodynamic response functions are obtained down to ultra-low temperatures. We extract the critical scaling exponents which dictate the power-law dependence of the transition temperature on the applied magnetic field. These are compared with recent experiments on candidate materials and with predictions for the Bose-Einstein condensation of magnons obtained in mean-field theory.Comment: RevTex, 4 pages with 5 figure

Modeling association between DNA copy number and gene expression with constrained piecewise linear regression splines

DNA copy number and mRNA expression are widely used data types in cancer studies, which combined provide more insight than separately. Whereas in existing literature the form of the relationship between these two types of markers is fixed a priori, in this paper we model their association. We employ piecewise linear regression splines (PLRS), which combine good interpretation with sufficient flexibility to identify any plausible type of relationship. The specification of the model leads to estimation and model selection in a constrained, nonstandard setting. We provide methodology for testing the effect of DNA on mRNA and choosing the appropriate model. Furthermore, we present a novel approach to obtain reliable confidence bands for constrained PLRS, which incorporates model uncertainty. The procedures are applied to colorectal and breast cancer data. Common assumptions are found to be potentially misleading for biologically relevant genes. More flexible models may bring more insight in the interaction between the two markers.Comment: Published in at http://dx.doi.org/10.1214/12-AOAS605 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org

Development of an experimental 10 T Nb3Sn dipole magnet for the CERN LHC

An experimental 1-m long twill aperture dipole magnet developed using a high-current Nb3Sn conductor in order to attain a magnetic field well beyond 10 T at 4.2 K is described. The emphasis in this Nb3Sn project is on the highest possible field within the known Large Hadron Collider (LHC) twin-aperture configuration. A design target of 11.5 T was chosen

Spatial periodic and homogeneous transverse stress loading on ITER TF Nb3Sn bronze and internal tin strand

The transport properties of the superconducting Nb3Sn layers in the strands strongly depend on the strain state. Knowledge of the influence of axial strain, periodic bending and contact stress on the critical current (Ic) of the used Nb3Sn strands is inevitable to gain sufficient confidence in an economic design and stable operation of ITER CICCs. In the past years we have measured the Ic and n-value of various ITER Nb3Sn strands with different layout in the TARSIS facility, when subjected to spatial periodic contact stress at a temperature of 4.2 K and in a magnet field of 12 T. Recently we have made the setup suitable for application of homogeneous load along the length of the wire (125 mm) in order to evaluate possible differences related to spatial stress and possible current distribution. We present an overview of the results obtained so far on an ITER TF bronze and internal tin strand.Comment: to be published in IEEE Trans Appl Supercon

Harmonically mode-locked Ti:Er:LiNbO3 waveguide laser

Active mode locking of an Er-diffusion-doped Ti:LiNbO3 waveguide laser by intracavity phase modulation to as high as the fourth harmonic (5.12 GHz) of the axial-mode frequency spacing is reported. The diode-pumped, pigtailed, and fully packaged laser with a monolithically integrated intracavity phase modulator has a threshold of 9 mW (incident pump power Ep jj c) and emits transform-limited pulses of >3.8-ps width and <5.6-pJ pulse energy (gain-switched mode locking) at 1602-nm wavelength (Es jj c). The relative change of the mode-locking frequency with the temperature is 3.65 3 1025y±C. The mode-locking acceptance bandwidth is 675 kHz near the axial-mode frequency spacing at approximately five times the threshold pump power

The muscle fiber type–fiber size paradox: hypertrophy or oxidative metabolism?

An inverse relationship exists between striated muscle fiber size and its oxidative capacity. This relationship implies that muscle fibers, which are triggered to simultaneously increase their mass/strength (hypertrophy) and fatigue resistance (oxidative capacity), increase these properties (strength or fatigue resistance) to a lesser extent compared to fibers increasing either of these alone. Muscle fiber size and oxidative capacity are determined by the balance between myofibrillar protein synthesis, mitochondrial biosynthesis and degradation. New experimental data and an inventory of critical stimuli and state of activation of the signaling pathways involved in regulating contractile and metabolic protein turnover reveal: (1) higher capacity for protein synthesis in high compared to low oxidative fibers; (2) competition between signaling pathways for synthesis of myofibrillar proteins and proteins associated with oxidative metabolism; i.e., increased mitochondrial biogenesis via AMP-activated protein kinase attenuates the rate of protein synthesis; (3) relatively higher expression levels of E3-ligases and proteasome-mediated protein degradation in high oxidative fibers. These observations could explain the fiber type–fiber size paradox that despite the high capacity for protein synthesis in high oxidative fibers, these fibers remain relatively small. However, it remains challenging to understand the mechanisms by which contractile activity, mechanical loading, cellular energy status and cellular oxygen tension affect regulation of fiber size. Therefore, one needs to know the relative contribution of the signaling pathways to protein turnover in high and low oxidative fibers. The outcome and ideas presented are relevant to optimizing treatment and training in the fields of sports, cardiology, oncology, pulmonology and rehabilitation medicine

Synthesis of Alkaline Earth Diazenides MAEN2 (MAE = Ca, Sr, Ba) by Controlled Thermal Decomposition of Azides under High Pressure

The alkaline earth diazenides MAEN2 with MAE = Ca, Sr and Ba were synthesized by a novel synthetic approach, namely, a controlled decomposition of the corresponding azides in a multianvil press at highpressure/ high-temperature conditions. The crystal structure of hitherto unknown calcium diazenide (space group I4/mmm (no. 139), a = 3.5747(6) Å, c = 5.9844(9) Å, Z = 2, wRp = 0.078) was solved and refined on the basis of powder X-ray diffraction data as well as that of SrN2 and BaN2. Accordingly, CaN2 is isotypic with SrN2 (space group I4/mmm (no. 139), a = 3.8054(2) Å, c = 6.8961(4) Å, Z = 2, wRp = 0.057) and the corresponding alkaline earth acetylenides (MAEC2) crystallizing in a tetragonally distorted NaCl structure type. In accordance with literature data, BaN2 adopts a more distorted structure in space group C2/c (no. 15) with a = 7.1608(4) Å, b = 4.3776(3) Å, c = 7.2188(4) Å, β = 104.9679(33)°, Z = 4 and wRp = 0.049). The N−N bond lengths of 1.202(4) Å in CaN2 (SrN2 1.239(4) Å, BaN2 1.23(2) Å) correspond well with a double-bonded dinitrogen unit confirming a diazenide ion [N2]2−. Temperature-dependent in situ powder X-ray diffractometry of the three alkaline earth diazenides resulted in formation of the corresponding subnitrides MAE2N (MAE = Ca, Sr, Ba) at higher temperatures. FTIR spectroscopy revealed a band at about 1380 cm−1 assigned to the N−N stretching vibration of the diazenide unit. Electronic structure calculations support the metallic character of alkaline earth diazenides