298 research outputs found
Characterization of extrachromosomal circular DNA (eccDNA) structure, function, and dynamics in a CHO K-1 clone
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Subthreshold dynamics of the neural membrane potential driven by stochastic synaptic input
In the cerebral cortex, neurons are subject to a continuous bombardment of synaptic inputs originating from the network's background activity. This leads to ongoing, mostly subthreshold membrane dynamics that depends on the statistics of the background activity and of the synapses made on a neuron. Subthreshold membrane polarization is, in turn, a potent modulator of neural responses. The present paper analyzes the subthreshold dynamics of the neural membrane potential driven by synaptic inputs of stationary statistics. Synaptic inputs are considered in linear interaction. The analysis identifies regimes of input statistics which give rise to stationary, fluctuating, oscillatory, and unstable dynamics. In particular, I show that (i) mere noise inputs can drive the membrane potential into sustained, quasiperiodic oscillations (noise-driven oscillations), in the absence of a stimulus-derived, intraneural, or network pacemaker; (ii) adding hyperpolarizing to depolarizing synaptic input can increase neural activity (hyperpolarization-induced activity), in the absence of hyperpolarization-activated currents
Quantum-Statistical Correlations and Single Particle Distributions for Slowly Expanding Systems with Temperature Profile
Competition among particle evaporation, temperature gradient and flow is
investigated in a phenomenological manner, based on a simultaneous analysis of
quantum statistical correlations and momentum distributions for a
non-relativistic, spherically symmetric, three-dimensionally expanding, finite
source. The parameters of the model emission function are constrained by fits
to neutron and proton momentum distributions and correlation functions in
intermediate energy heavy-ion collisions. The temperature gradient is related
to the momentum dependence of the radius parameters of the two-particle
correlation function, as well as to the momentum-dependent temperature
parameter of the single particle spectrum, while a long duration of particle
evaporation is found to be responsible for the low relative momentum behavior
of the two-particle correlations.Comment: 20 pages + 5 ps figures, ReVTeX, uses psfig.sty, the description is
extended to include final state interactions, phenomenological evaporation
and to fit intermediate energy heavy ion proton and neutron spectrum and
correlation dat
Measurement of the Positive Muon Lifetime and Determination of the Fermi Constant to Part-per-Million Precision
We report a measurement of the positive muon lifetime to a precision of 1.0
parts per million (ppm); it is the most precise particle lifetime ever
measured. The experiment used a time-structured, low-energy muon beam and a
segmented plastic scintillator array to record more than 2 x 10^{12} decays.
Two different stopping target configurations were employed in independent
data-taking periods. The combined results give tau_{mu^+}(MuLan) =
2196980.3(2.2) ps, more than 15 times as precise as any previous experiment.
The muon lifetime gives the most precise value for the Fermi constant:
G_F(MuLan) = 1.1663788 (7) x 10^-5 GeV^-2 (0.6 ppm). It is also used to extract
the mu^-p singlet capture rate, which determines the proton's weak induced
pseudoscalar coupling g_P.Comment: Accepted for publication in Phys. Rev. Let
Measurement of the Rate of Muon Capture in Hydrogen Gas and Determination of the Proton's Pseudoscalar Coupling
The rate of nuclear muon capture by the proton has been measured using a new
experimental technique based on a time projection chamber operating in
ultra-clean, deuterium-depleted hydrogen gas at 1 MPa pressure. The capture
rate was obtained from the difference between the measured
disappearance rate in hydrogen and the world average for the decay
rate. The target's low gas density of 1% compared to liquid hydrogen is key to
avoiding uncertainties that arise from the formation of muonic molecules. The
capture rate from the hyperfine singlet ground state of the atom is
measured to be , from which the induced
pseudoscalar coupling of the nucleon, , is
extracted. This result is consistent with theoretical predictions for
that are based on the approximate chiral symmetry of QCD.Comment: submitted to Phys.Rev.Let
Effect of Flow on Caloric Curve for Finite Nuclei
In a finite temperature Thomas-Fermi theory, we construct caloric curves for
finite nuclei enclosed in a freeze-out volume few times the normal nuclear
volume, with and without inclusion of flow. Without flow, the caloric curve
indicates a smooth liquid-gas phase transition whereas with flow, the
transition may be very sharp. We discuss these results in the context of two
recent experiments, one for heavy symmetric system (Au + Au at 600A MeV) and
the other for highly asymmetric system (Au + C at 1A GeV) where different
behaviours in the caloric curves are seen.Comment: 11 pages revtex; 4 figs; version to appear in Phys. Rev. Let
Improved Measurement of the Positive Muon Lifetime and Determination of the Fermi Constant
The mean life of the positive muon has been measured to a precision of 11 ppm
using a low-energy, pulsed muon beam stopped in a ferromagnetic target, which
was surrounded by a scintillator detector array. The result, tau_mu =
2.197013(24) us, is in excellent agreement with the previous world average. The
new world average tau_mu = 2.197019(21) us determines the Fermi constant G_F =
1.166371(6) x 10^-5 GeV^-2 (5 ppm). Additionally, the precision measurement of
the positive muon lifetime is needed to determine the nucleon pseudoscalar
coupling g_P.Comment: As published version (PRL, July 2007
Muon Physics: A Pillar of the Standard Model
Since its discovery in the 1930s, the muon has played an important role in
our quest to understand the sub-atomic theory of matter. The muon was the first
second-generation standard-model particle to be discovered, and its decay has
provided information on the (Vector -Axial Vector) structure of the weak
interaction, the strength of the weak interaction, G_F, and the conservation of
lepton number (flavor) in muon decay. The muon's anomalous magnetic moment has
played an important role in restricting theories of physics beyond the standard
standard model, where at present there is a 3.4 standard-deviation difference
between the experiment and standard-model theory. Its capture on the atomic
nucleus has provided valuable information on the modification of the weak
current by the strong interaction which is complementary to that obtained from
nuclear beta decay.Comment: 8 pages, 9 figures. Invited paper for the Journal of Physical Society
in Japan (JPSJ), Special Topics Issue "Frontiers of Elementary Particle
Physics, The Standard Model and beyond
Psychological determinants of whole-body endurance performance
Background: No literature reviews have systematically identified and evaluated research on the psychological determinants of endurance performance, and sport psychology performance-enhancement guidelines for endurance sports are not founded on a systematic appraisal of endurance-specific research.
Objective: A systematic literature review was conducted to identify practical psychological interventions that improve endurance performance and to identify additional psychological factors that affect endurance performance. Additional objectives were to evaluate the research practices of included studies, to suggest theoretical and applied implications, and to guide future research.
Methods: Electronic databases, forward-citation searches, and manual searches of reference lists were used to locate relevant studies. Peer-reviewed studies were included when they chose an experimental or quasi-experimental research design, a psychological manipulation, endurance performance as the dependent variable, and athletes or physically-active, healthy adults as participants.
Results: Consistent support was found for using imagery, self-talk, and goal setting to improve endurance performance, but it is unclear whether learning multiple psychological skills is more beneficial than learning one psychological skill. The results also demonstrated that mental fatigue undermines endurance performance, and verbal encouragement and head-to-head competition can have a beneficial effect. Interventions that influenced perception of effort consistently affected endurance performance.
Conclusions: Psychological skills training could benefit an endurance athlete. Researchers are encouraged to compare different practical psychological interventions, to examine the effects of these interventions for athletes in competition, and to include a placebo control condition or an alternative control treatment. Researchers are also encouraged to explore additional psychological factors that could have a negative effect on endurance performance. Future research should include psychological mediating variables and moderating variables. Implications for theoretical explanations of endurance performance and evidence-based practice are described
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