Lattice fence and hedge barriers around an apiary increase honey bee flight height and decrease stings to people nearby

Urban beekeeping is becoming more popular in the UK. One of the challenges faced by urban beekeepers is finding a suitable apiary location. Honey bees are often perceived as a nuisance, mainly due to their stinging behaviour. Here, we experimentally test the assumption that barriers around an apiary such as walls or fences, force the bees to fly above human height, thereby reducing collisions with people and, consequently, stinging. The experiment was conducted in two apiaries using two common types of barrier: a lattice fence (trellis) and hedge. Barriers were 2 m high, which is taller than > 99% of humans and is also the maximum height allowed by UK planning regulations for garden fences or walls. We found that barriers were effective at both raising the mean honey bee flight height and reducing stinging. However, the effects were only seen when the barrier had been in place for a few days, not immediately after the barrier was put in place. Although this raises interesting questions regarding honey bee navigation and memory, it is not a problem for beekeepers, as any barrier placed around an apiary will be permanent. The effect of the barriers on raising bee flight height to a mean of c. 2.2-2.5 m was somewhat weak and inconsistent, probably because the bees flew high, mean of c. 1.6-2.0 m, even in the absence of a barrier. As barriers can also reduce wind exposure, improve security and are inexpensive, we recommend their use around urban apiaries in places such as private gardens or allotments, where nuisance to humans is likely to be a problem

Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway

Pseudomonas aeruginosa (Pa) infection is a major cause of airway inflammation in immunocompromised and cystic fibrosis (CF) patients. Mitogen-activated protein (MAP) and tyrosine kinases are integral to inflammatory responses and are therefore potential targets for novel anti-inflammatory therapies. We have determined the involvement of specific kinases in Pa-induced inflammation. The effects of kinase inhibitors against p38MAPK, MEK 1/2, JNK 1/2, Syk or c-Src, a combination of a p38MAPK with Syk inhibitor, or a novel narrow spectrum kinase inhibitor (NSKI), were evaluated against the release of the proinflammatory cytokine/chemokine, IL-6 and CXCL8 from BEAS-2B and CFBE41o- epithelial cells by Pa. Effects of a Syk inhibitor against phosphorylation of the MAPKs were also evaluated. IL-6 and CXCL8 release by Pa were significantly inhibited by p38MAPK and Syk inhibitors (p<0.05). Phosphorylation of HSP27, but not ERK or JNK, was significantly inhibited by Syk kinase inhibition. A combination of p38MAPK and Syk inhibitors showed synergy against IL-6 and CXCL8 induction and an NSKI completely inhibited IL-6 and CXCL8 at low concentrations. Pa-induced inflammation is dependent on p38MAPK primarily, and Syk partially, which is upstream of p38MAPK. The NSKI suggests that inhibiting specific combinations of kinases is a potent potential therapy for Pa-induced inflammation

Efficient routing of single photons by one atom and a microtoroidal cavity

Single photons from a coherent input are efficiently redirected to a separate output by way of a fiber-coupled microtoroidal cavity interacting with individual Cesium atoms. By operating in an overcoupled regime for the input-output to a tapered fiber, our system functions as a quantum router with high efficiency for photon sorting. Single photons are reflected and excess photons transmitted, as confirmed by observations of photon antibunching (bunching) for the reflected (transmitted) light. Our photon router is robust against large variations of atomic position and input power, with the observed photon antibunching persisting for intracavity photon number 0.03 \lesssim n \lesssim 0.7

The Opacity of Spiral Galaxy Disks V: dust opacity, HI distributions and sub-mm emission

The opacity of spiral galaxy disks, from counts of distant galaxies, is compared to HI column densities. The opacity measurements are calibrated using the ``Synthetic Field Method'' from Gonzalez et al (1998) and Holwerda et al. (2005a). When compared for individual disks, the HI column density and dust opacity do not seem to be correlated as HI and opacity follow different radial profiles. To improve statistics, an average radial opacity profile is compared to an average HI profile. Compared to dust-to-HI estimates from the literature, more extinction is found in this profile. This difference may be accounted for by an underestimate of the dust in earlier measurements due to their dependence on dust temperature. Since the SFM is insensitive to the dust temperature, the ratio between the SFM opacity and HI could very well be indicative of the true ratio. Earlier claims for a radially extended cold dust disk were based on sub-mm observations. A comparison between sub-mm observations and counts of distant galaxies is therefore desirable. We present the best current example of such a comparison, M51, for which the measurements seem to agree. However, this remains an area where improved counts of distant galaxies, sub-mm observations and our understanding of dust emissivity are needed.Comment: 8 pages, 5 figures, 1 table, accepted by A&

Probing lepton flavour violation in νμ+N→τ+...\nu_{\mu} + N \to \tau + ... scattering and μ→tau\mu \to tau conversion on nucleons

We study lepton flavour-violating interactions which could result in the $\tau$-lepton production in the $\nu_{\mu}N$ scattering or in $\mu \to \tau$ conversion on nucleons at high energies. Phenomenological bounds on the strength of $\bar{\tau}\nu_{\mu}\bar{q}q^{'}$ interactions are extracted from the combined result of the NOMAD and CHORUS experiments on searching for $\nu_{\mu} - \nu_{\tau}$ oscillations. Some of these bounds supersede limits from rare decays. We also propose a ``missing energy'' type experiment searching for $\mu - \tau$ conversion on nucleons. The experiment can be performed at a present accelerator or at a future neutrino factory.Comment: 13 pages, 4 figure

The Origin of the Dust Arch in the Halo of NGC 4631: An Expanding Superbubble?

We study the nature and the origin of the dust arch in the halo of the edge-on galaxy NGC 4631 detected by Neininger & Dumke (1999). We present CO observations made using the new On-The-Fly mapping mode with the FCRAO 14m telescope, and find no evidence for CO emission associated with the dust arch. Our examination of previously published HI data shows that if previous assumptions about the dust temperature and gas/dust ratio are correct, then there must be molecular gas associated with the arch, below our detection threshold. If this is true, then the molecular mass associated with the dust arch is between 1.5 x 10^8 M(sun)and 9.7 x 10^8 M(sun), and likely towards the low end of the range. A consequence of this is that the maximum allowed value for the CO-to-H_2 conversion factor is 6.5 times the Galactic value, but most likely closer to the Galactic value. The kinematics of the HI apparently associated with the dust arch reveal that the gas here is not part of an expanding shell or outflow, but is instead two separate features (a tidal arm and a plume of HI sticking out into the halo) which are seen projected together and appear as a shell. Thus there is no connection between the dust "arch" and the hot X-ray emitting gas that appears to surround the galaxy Wang et al. (2001).Comment: 14 pages, including 4 figures. Accepted by A.J. for March 200

Computational Design of High Efficiency Release Targets for Use at ISOL Facilities

This report describes efforts made at the Oak Ridge National Laboratory to design high-efficiency-release targets that simultaneously incorporate the short diffusion lengths, high permeabilities, controllable temperatures, and heat removal properties required for the generation of useful radioactive ion beam (RIB) intensities for nuclear physics and astrophysics research using the isotope separation on-line (ISOL) technique. Short diffusion lengths are achieved either by using thin fibrous target materials or by coating thin layers of selected target material onto low-density carbon fibers such as reticulated vitreous carbon fiber (RVCF) or carbon-bonded-carbon-fiber (CBCF) to form highly permeable composite target matrices. Computational studies which simulate the generation and removal of primary beam deposited heat from target materials have been conducted to optimize the design of target/heat-sink systems for generating RIBs. The results derived tlom diffusion release-rate simulation studies for selected targets and thermal analyses of temperature distributions within a prototype target/heat-sink system subjected to primary ion beam irradiation will be presented in this report

The Opacity of Spiral Galaxy Disks VI: Extinction, stellar light and color

In this paper we explore the relation between dust extinction and stellar light distribution in disks of spiral galaxies. Extinction influences our dynamical and photometric perception of disks, since it can distort our measurement of the contribution of the stellar component. To characterize the total extinction by a foreground disk, Gonzalez et al. (1998) proposed the ``Synthetic Field Method'' (SFM), which uses the calibrated number of distant galaxies seen through the foreground disk as a direct indication of extinction. The method is described in Gonzalez et al. (1998) and Holwerda et al. (2005a). To obtain good statistics, the method was applied to a set of HST/WFPC2 fields Holwerda et al. (2005b) and radial extinction profiles were derived, based on these counts. In the present paper, we explore the relation of opacity with surface brightness or color from 2MASS images, as well as the relation between the scalelengths for extinction and light in the I band. We find that there is indeed a relation between the opacity (A_I) and the surface brightness, particularly at the higher surface brightnesses. No strong relation between near infrared (H-J, H-K) color and opacity is found. The scalelengths of the extinction are uncertain for individual galaxies but seem to indicate that the dust distribution is much more extended than the stellar light. The results from the distant galaxy counts are also compared to the reddening derived from the Cepheids light-curves Freedman et al. (2001). The extinction values are consistent, provided the selection effect against Cepheids with higher values of A_I is taken into account. The implications from these relations for disk photometry, M/L conversion and galaxy dynamical modeling are briefly discussed.Comment: 9 pages, 2 tables, 10 figures, accepted by A&