Keuzes tijdens de pensioenopbouw: de effecten van nudging met volgorde en standaardopties.

Hervorming Sociale Regelgevin

Dutch disease-cum-financialization booms and external balance cycles in developing countries

We formally investigate the medium-to-long-run dynamics emerging out of a Dutch disease-cum-financialization phenomenon. We take inspiration from the most recent Colombian development pattern. The “pure” Dutch disease first causes deindustrialization by permanently appreciating the economy’s exchange rate in the long run. Financialization, i.e. booming capital inflows taking place in a climate of natural resource-led financial over-optimism, causes medium-run exchange rate volatility and macroeconomic instability. This jeopardizes manufacturing development even further by raising macroeconomic uncertainty. We advise the adoption of capital controls and a developmentalist monetary policy to tackle these two distinct but often intertwined phenomena

Clinical longevity of intracoronal restorations made of gold, lithium disilicate, leucite, and indirect resin composite:a systematic review and meta-analysis

OBJECTIVES: The aim of this systematic review and meta-analysis is to assess the comparative clinical success and survival of intracoronal indirect restorations using gold, lithium disilicate, leucite, and indirect composite materials.MATERIAL AND METHODS: This systematic review and meta-analysis were conducted following the Cochrane Handbook for Systematic Reviews of Interventions and PRISMA guidelines. The protocol for this study was registered in PROSPERO (registration number: CRD42021233185). A comprehensive literature search was conducted across various databases and sources, including PubMed/Medline, Embase, Cochrane Library, Web of Science, ClinicalTrials.gov, and gray literature. A total of 7826 articles were screened on title and abstract. Articles were not excluded based on the vitality of teeth, the language of the study, or the observation period. The risk difference was utilized for the analyses, and a random-effects model was applied. All analyses were conducted with a 95% confidence interval (95% CI). The calculated risk differences were derived from the combined data on restoration survival and failures obtained from each individual article. The presence of heterogeneity was assessed using the I2 statistic, and if present, the heterogeneity of the data in the articles was evaluated using the non-parametric chi-squared statistic (p &lt; 0.05).RESULTS: A total of 12 eligible studies were selected, which included 946 restorations evaluated over a minimum observation period of 1 year and a maximum observation period of 7 years. Results of the meta-analysis indicated that intracoronal indirect resin composite restorations have an 18% higher rate of failure when compared to intracoronal gold restorations over 5-7 years of clinical service (risk difference =  - 0.18 [95% CI: - 0.27, - 0.09]; p = .0002; I2 = 0%). The meta-analysis examining the disparity in survival rates between intracoronal gold and leucite restorations could not be carried out due to methodological differences in the studies.CONCLUSIONS: According to the currently available evidence, medium-quality data indicates that lithium disilicate and indirect composite materials demonstrate comparable survival rates in short-term follow-up. Furthermore, intracoronal gold restorations showed significantly higher survival rates, making them a preferred option over intracoronal indirect resin-composite restorations. Besides that, the analysis revealed no statistically significant difference in survival rates between leucite and indirect composite restorations. The short observation period, limited number of eligible articles, and low sample size of the included studies were significant limitations.CLINICAL SIGNIFICANCE: Bearing in mind the limitations of the reviewed literature, this systematic review and meta-analysis help clinicians make evidence-based decisions on how to restore biomechanically compromised posterior teeth.</p

Differential Calculi on Commutative Algebras

A differential calculus on an associative algebra A is an algebraic analogue of the calculus of differential forms on a smooth manifold. It supplies A with a structure on which dynamics and field theory can be formulated to some extent in very much the same way we are used to from the geometrical arena underlying classical physical theories and models. In previous work, certain differential calculi on a commutative algebra exhibited relations with lattice structures, stochastics, and parametrized quantum theories. This motivated the present systematic investigation of differential calculi on commutative and associative algebras. Various results about their structure are obtained. In particular, it is shown that there is a correspondence between first order differential calculi on such an algebra and commutative and associative products in the space of 1-forms. An example of such a product is provided by the Ito calculus of stochastic differentials. For the case where the algebra A is freely generated by `coordinates' x^i, i=1,...,n, we study calculi for which the differentials dx^i constitute a basis of the space of 1-forms (as a left A-module). These may be regarded as `deformations' of the ordinary differential calculus on R^n. For n < 4 a classification of all (orbits under the general linear group of) such calculi with `constant structure functions' is presented. We analyse whether these calculi are reducible (i.e., a skew tensor product of lower-dimensional calculi) or whether they are the extension (as defined in this article) of a one dimension lower calculus. Furthermore, generalizations to arbitrary n are obtained for all these calculi.Comment: 33 pages, LaTeX. Revision: A remark about a quasilattice and Penrose tiling was incorrect in the first version of the paper (p. 14

A cluster of blood-based protein biomarkers associated with decreased cerebral blood flow relates to future cardiovascular events in patients with cardiovascular disease

Biological processes underlying decreased cerebral blood flow (CBF) in patients with cardiovascular disease (CVD) are largely unknown. We hypothesized that identification of protein clusters associated with lower CBF in patients with CVD may explain underlying processes. In 428 participants (74% cardiovascular diseases; 26% reference participants) from the Heart-Brain Connection Study, we assessed the relationship between 92 plasma proteins from the Olink® cardiovascular III panel and normal-appearing grey matter CBF, using affinity propagation and hierarchical clustering algorithms, and generated a Biomarker Compound Score (BCS). The BCS was related to cardiovascular risk and observed cardiovascular events within 2-year follow-up using Spearman correlation and logistic regression. Thirteen proteins were associated with CBF (ρSpearman range: −0.10 to −0.19, pFDR-corrected &lt;0.05), and formed one cluster. The cluster primarily reflected extracellular matrix organization processes. The BCS was higher in patients with CVD compared to reference participants (pFDR-corrected &lt;0.05) and was associated with cardiovascular risk (ρSpearman 0.42, p &lt; 0.001) and cardiovascular events (OR 2.05, p &lt; 0.01). In conclusion, we identified a cluster of plasma proteins related to CBF, reflecting extracellular matrix organization processes, that is also related to future cardiovascular events in patients with CVD, representing potential targets to preserve CBF and mitigate cardiovascular risk in patients with CVD.</p

Classification of bicovariant differential calculi on the Jordanian quantum groups GL_{g,h}(2) and SL_{h}(2) and quantum Lie algebras

We classify all 4-dimensional first order bicovariant calculi on the Jordanian quantum group GL_{h,g}(2) and all 3-dimensional first order bicovariant calculi on the Jordanian quantum group SL_{h}(2). In both cases we assume that the bicovariant bimodules are generated as left modules by the differentials of the quantum group generators. It is found that there are 3 1-parameter families of 4-dimensional bicovariant first order calculi on GL_{h,g}(2) and that there is a single, unique, 3-dimensional bicovariant calculus on SL_{h}(2). This 3-dimensional calculus may be obtained through a classical-like reduction from any one of the three families of 4-dimensional calculi on GL_{h,g}(2). Details of the higher order calculi and also the quantum Lie algebras are presented for all calculi. The quantum Lie algebra obtained from the bicovariant calculus on SL_{h}(2) is shown to be isomorphic to the quantum Lie algebra we obtain as an ad-submodule within the Jordanian universal enveloping algebra U_{h}(sl(2)) and also through a consideration of the decomposition of the tensor product of two copies of the deformed adjoint module. We also obtain the quantum Killing form for this quantum Lie algebra.Comment: 33 pages, AMSLaTeX, misleading remark remove

Preoperative MRI brain phenotypes are related to postoperative delirium in older individuals

Ophthalmic researc