Scientific Report Number 2

I. INTRODUCTION The earlier orbits and ephemerides for the Soviet satellites were not sufficiently accurate to be very useful in making observations in Alaska. Extrapolations from our own observations gave better predictions. This merely pointed out the fact that rough observations of meridian transits at high latitudes will give better values of the inclination of the orbit than precision observations at low latitudes. Hence, it was decided to observe visually the meridian transits estimating the altitude by noting the position with respect to the stars or using crude alidade measurements. The times of the earlier observations were observed on a watch or clock and the clock correction obtained from WWV. Later the times were determined with the aid of stop watches, taking time intervals from WWV signals. This rather meager program of optical observations of the Soviet satellites was undertaken to give supplementary data for use of the radio observations, and particularly to assist in the prediction of position of the satellite so that the 61-foot radar of Stanford Research Institute could be set accurately enough to observe it (the beam width at the half-power points is about 3°). This report contains primarily the visual observations made at the Geophysical Institute by various members of the staff, and a series of observations by Olaf Halverson at Nome, Alaska. In addition there is a short discussion of the geometry of the trajectory, the illumination of a circumpolar satellite, and a note on the evaluation of Brouwer's moment factors.Air Force Contract No. AF 30(635)-2887 Project No. 5535 - Task 45774 Rome Air Development Center Griffiss Air Force Base Rome, New YorkI. Introduction -- II. Visual Observations -- III. Geometry of the Trajectory -- IV. Seasonal Illumination of a Circumpolar Earth Satellite at its Extreme Latitude Orbit-Point. -- V. Tentative Evaluation of Brouwer's Moment Factors.Ye

Commerical airlines and the grooved runway concept

Commercial airlines and grooved runway concep

Test experience on an ultrareliable computer communication network

The dispersed sensor processing mesh (DSPM) is an experimental, ultra-reliable, fault-tolerant computer communications network that exhibits an organic-like ability to regenerate itself after suffering damage. The regeneration is accomplished by two routines - grow and repair. This paper discusses the DSPM concept for achieving fault tolerance and provides a brief description of the mechanization of both the experiment and the six-node experimental network. The main topic of this paper is the system performance of the growth algorithm contained in the grow routine. The characteristics imbued to DSPM by the growth algorithm are also discussed. Data from an experimental DSPM network and software simulation of larger DSPM-type networks are used to examine the inherent limitation on growth time by the growth algorithm and the relationship of growth time to network size and topology

Disease-associated mutations in KCNE potassium channel subunits (MiRPs) reveal promiscuous disruption of multiple currents and conservation of mechanism.

KCNE genes encode single transmembrane-domain subunits, the MinK-related peptides (MiRPs), which assemble with pore-forming alpha subunits to establish the attributes of potassium channels in vivo. To investigate whether MinK, MiRP1, and MiRP2 operate similarly with their known native alpha subunit partners (KCNQ1, HERG, and Kv3.4, respectively) two conserved residues associated with human disease and influential in channel function were evaluated. As MiRPs assemble with a variety of alpha subunits in experimental cells and may do so in vivo, each peptide was also assessed with the other two alpha subunits. Inherited mutation of aspartate to asparagine (D --> N) to yield D76N-MinK is linked to cardiac arrhythmia and deafness; the analogs D82N-MiRP1 and D90N-MiRP2 were studied. Mutation of arginine to histidine (R --> H) to yield R83H-MiRP2 is associated with periodic paralysis; the analogs K69H-MinK and K75H-MiRP1 were also studied. Macroscopic and single-channel currents showed that D --> N mutations suppressed a subset of functions whereas R/K --> H changes altered the activity of MinK, MiRP1, and MiRP2 with all three alpha subunits. The findings indicate that the KCNE peptides interact similarly with different alpha subunits and suggest a hypothesis: that clinical manifestations of inherited KCNE point mutations result from disruption of multiple native currents via promiscuous interactions

1. Strengthening International Regulation Through Transnational New Governance: Overcoming the Orchestration Deficit. 2. International Regulation without International Government: Improving IO Performance through Orchestration

1. A new kind of international regulatory system is spontaneously arising out of the failure of international 'Old Governance' (i.e., treaties and intergovernmental organizations) to adequately regulate international business. Nongovernmental organizations, business firms, and other actors, singly and in novel combinations, are creating innovative institutions to apply transnational norms to business. These institutions are predominantly private and operate through voluntary standards. The Authors depict the diversity of these new regulatory institutions on the 'Governance Triangle,' according to the roles of different actors in their operations. To analyze this complex system, we adapt the domestic 'New Governance' model of regulation to the international setting. 'Transnational New Governance' potentially provides many benefits of New Governance and is particularly suitable for international regulation because it demands less of states and intergovernmental organizations (IGOs). However, Transnational New Governance does require states and IGOs to act as orchestrators of the international regulatory system, and that system currently suffers from a significant orchestration deficit. If states and IGOs expanded 'directive' and especially 'facilitative' orchestration of the Transnational New Governance system, they could strengthen high-quality private regulatory standards, improve the international regulatory system, and better achieve their own regulatory goals. 2. International organizations (IOs) have been widely criticized as ineffective. Yet scholars and practitioners assessing IO performance frequently focus on traditional modes of governance such as treaties and inter-state dispute-resolution mechanisms. When they observe poor performance, moreover, they often prescribe a strengthening of those same activities. We call this reliance on traditional state-based mechanisms 'International Old Governance' (IOG). A better way to understand and improve IO performance is to consider the full range of ways in which IOs can and do operate - including, increasingly, by reaching out to private actors and institutions, collaborating with them, and supporting and shaping their activities. Such actions are helping to develop an intricate global network of public, private and mixed institutions and norms, partially orchestrated by IOs, that we call 'Transnational New Governance' (TNG). With proper orchestration by IOs, TNG can ameliorate both 'state failure' - the inadequacies of IOG - and 'market failure' - the problems that result when the creation and evolution of norm-setting institutions is highly decentralized. Orchestration thus provides a significant way for IOs to improve their regulatory performance. Some IOs already engage actively with private actors and institutions - we provide a range of illustrations, highlighting the activities of the UN Environment Programme (UNEP). Yet there remains a significant 'orchestration deficit' that provides real opportunities for IOs. We draw on the lessons of existing IO activities to suggest additional possibilities for improving IO performance. -- 1. Ein internationales regulatorisches System neuer Art entsteht derzeit spontan aus dem Versagen der internationalen 'Old Governance' - also der bestehenden internationalen Verträge und Organisationen - dabei, den internationalen Handel angemessen zu regulieren. Nichtregierungsorganisationen, Unternehmen und andere Akteure - allein und in ganz neuen Kombinationen - schaffen sich neue internationale Einrichtungen, um transnationale Normen auf internationale Geschäftstätigkeit anzuwenden. Es geht dabei vornehmlich um private Einrichtungen, die vor allem über freiwillige Standardbefolgung wirken. In diesem Beitrag werden die unterschiedlichen Regulierungseinrichtungen als Teil eines 'Governance Dreiecks' beschreiben und das geschieht vor allem in Blick darauf, welche Rollen die unterschiedlichen Akteure in ihrer Tätigkeit spielen. Um dieses komplexe System zu untersuchen passen wir das innenpolitische Regulierungsmodell der 'New Governance' an den internationalen Rahmen an. Die 'Transnational New Governance' enthält viele Vorteile der 'New Governance' und sie ist für die internationale Regulierung besonders angemessen, weil sie geringere Anforderungen an die Staatenwelt und an die intergouvernementalen Organisationen, die IGOs, stellen. Allerdings ist es für eine wirksame 'Transnational New Governance' weiterhin erforderlich, dass die Staaten und die IGOs das internationale regulatorische System 'orchestrieren'. Das heutige internationale regulatorische System leidet allerdings unter einem Orchestrierungsdefizit. Würden die Staaten und die IGOs die 'anweisende' und 'ermöglichende' Orchestrierungsfunktion des 'Transnational New Governance System' ausbauen, dann stärkten sie die privaten regulatorischen Standards von hoher Qualität, verbesserten das internationale regulatorische System und könnten ihre eigenen regulatorischen Ziele besser verwirklichen. 2. Internationale Organisationen (IOs) werden vielfach ob Ihrer Ineffizienz kritisiert. Allerdings konzentrieren sich Wissenschaftler und Praktiker bei dieser Bewertung der Leistungsfähigkeit von IOs häufig auf Maßstäbe, die den herkömmlichen Formen von Governance - wie internationalen Verträgen und den Mechanismen für die Schlichtung zwischenstaatlicher Konflikte - entlehnt sind. Soweit eine ungenügende Leistung festgestellt wird, empfehlen sie zudem meist, Tätigkeiten der traditionellen Art zu verstärken. Wir bezeichnen dies als ein Sich-Verlassen auf die herkömmlichen staats-basierten Mechanismen, als 'International Old Governance' (IOG). Man versteht die IOs besser und verbessert ihre Leistungsfähigkeit aber der Situation weitaus angemessener, wenn man die gesamte Vielfalt wirklicher und möglicher IO-Tätigkeiten in den Blick nimmt: Das umfasst vor allem, dass die IOs private Akteure und Organisationen einbeziehen, mit ihnen zusammenarbeiten, ihre Aktivitäten stützen, sie formen und ihnen Richtung geben. Diese Tätigkeiten schaffen ein fein gesponnenes globales Netzwerk von öffentlichen, privaten und gemischten Organisationen und Normen, das seinerseits teilweise durch die IOs orchestriert wird. Dieses Netzwerk bezeichnen wir als 'Transnational New Governance' (TNG). Wenn die Orchestrierung durch IOs gut funktioniert kann sie auch Staatsversagen (state failure) abmildern - also hier die Inadäquanzen von 'International Organization Governance' - und ebenso kann sie Marktversagen ausgleichen, also die Probleme, die sich ergeben wenn Herausbildung und Schaffung normgebender Einrichtungen höchst dezentralisiert verläuft. Über die Orchestrierung können die IOs auch die Leistungsfähigkeit ihrer Regulierungen erhöhen. Einige IOs sind schon jetzt stark zusammen mit privaten Akteuren und Einrichtungen unterwegs; in diesem Beitrag mustern wir das Spektrum solcher Aktivitäten. Wir betonen dabei die Unternehmungen des UN Environment Programme (UNEP), des Umweltprogramms der VN. Allerdings verbleibt ein erhebliches 'Orchestrierungsdefizit', das für die IOs zugleich Herausforderung und Chance ist. Wir stützten uns auf den Erfahrungsschatz der vorgefundenen IO-Aktivitäten, um den Möglichkeitsraum der IOs für die Zukunft auszumessen und Maßnahmen zur Verbesserung der Leistungsfähigkeit von IOs anzuregen.

Parrondo's games with chaotic switching

This paper investigates the different effects of chaotic switching on Parrondo's games, as compared to random and periodic switching. The rate of winning of Parrondo's games with chaotic switching depends on coefficient(s) defining the chaotic generator, initial conditions of the chaotic sequence and the proportion of Game A played. Maximum rate of winning can be obtained with all the above mentioned factors properly set, and this occurs when chaotic switching approaches periodic behavior.Comment: 11 pages, 9 figure

Incidence angle bounds for lip flow separation of three 13.97-centimeter-diameter inlets

Low speed wind tunnel tests were conducted to establish a procedure for determining inlet-lip flow separation and to make preliminary examination of the incidence angle bounds for lip flow separation on inlets intended for the nacelles of STOL (short takeoff and landing) aircraft. Three inlets were tested. Two of the inlets had short centerbodies with lower lip area contraction ratios of 1.30 and 1.44. The third inlet had a cylindrical centerbody extended forward into the inlet throat with a lower lip area contraction ratio of 1.44. The inlets were sized to fit a 13.97 centimeter-diameter fan. For inlet throat Mach numbers less than about 0.43, the lip flow separation angle was increased by either increasing the ratio of throat velocity to freestream velocity (Vt/Vo) or by increasing the lower lip area contraction ratio. For throat Mach numbers greater than a certain value (ranging from 0.43 to 0.52), increasing throat Mach number in some cases resulted in a decrease in the lip flow separation angle. Extending a cylindrical centerbody into the inlet throat increased the flow separation angle for nearly all values of Vt/Vo

Behavior and weight correlates of weight-control efforts in Australian women living in disadvantage : the READI study

BackgroundWith increasing obesity rates worldwide, more and more people are actively attempting to lose weight or avoid weight gain, but relatively little is known about what specific behaviors comprise these efforts and which, if any, are associated with better weight control over time.MethodsThis paper reports relationships between body weight, weight-control efforts and related behaviors over a three-year period in 1,634 Australian women. The women were purposefully recruited from 80 disadvantaged neighborhoods in Victoria, Australia. Weight loss efforts were categorized as trying to lose weight, trying to prevent weight gain and no weight-control efforts. Behavioral correlates examined included different kinds of physical activity and consumption of a number of specific foods types.Results and discussionSelf-reported body weight at baseline was higher in women trying to lose weight. Frequency of consumption of low energy density foods was positively associated with reported weight-control efforts, as was frequency of reported total and leisure-time physical activity. Longitudinal associations between changes in weight-control efforts and changes in behaviors were consistent with the cross-sectional findings. At three-year follow up, however, weight-control efforts were not associated with change in body weight. More detailed analyses of specific food choices suggested that part of the explanation of no effect of reported weight-control efforts and weight over time might be that people are not as well-informed as they should be about the energy density of some common foods. In particular, those reporting engagement in weight-control efforts reported reducing consumption of carbohydrate-containing foods such as bread and potatoes more than is justified by their energy content, while they reported increasing consumption of some high energy density foods (e.g., cheese and nuts).ConclusionIt is tentatively concluded that women living in disadvantaged neighborhoods understand messages about weight-control (more activity and foods with lower fat and lower energy density) but that some foods eaten more by women engaged in weight control may reduce the effectiveness of these efforts.<br /

Phosphorylation and protonation of neighboring MiRP2 sites: function and pathophysiology of MiRP2-Kv3.4 potassium channels in periodic paralysis.

MinK-related peptide 2 (MiRP2) and Kv3.4 subunits assemble in skeletal muscle to create subthreshold, voltage-gated potassium channels. MiRP2 acts on Kv3.4 to shift the voltage dependence of activation, speed recovery from inactivation, suppress cumulative inactivation and increase unitary conductance. We previously found an R83H missense mutation in MiRP2 that segregated with periodic paralysis in two families and diminished the effects of MiRP2 on Kv3.4. Here we show that MiRP2 has a single, functional PKC phosphorylation site at serine 82 and that normal MiRP2-Kv3.4 function requires phosphorylation of the site. The R83H variant does not prevent PKC phosphorylation of neighboring S82; rather, the change shifts the voltage dependence of activation and endows MiRP2-Kv3.4 channels with sensitivity to changes in intracellular pH across the physiological range. Thus, current passed by single R83H channels decreases as internal pH is lowered (pK(a) approximately 7.3, consistent with histidine protonation) whereas wild-type channels are largely insensitive. These findings identify a key regulatory domain in MiRP2 and suggest a mechanistic link between acidosis and episodes of periodic paralysis