Probing Color Response - Wakes in a Color Plasma

The wake induced in a hot QCD medium by a high momentum parton (jet precursor) is calculated in the framework of linear response theory. Two different scenarios are discussed: a weakly coupled quark gluon plasma (pQGP) as described by hard-thermal loop (HTL) perturbation theory and a strongly cupled QGP (sQGP) with the properties of a quantum liquid. In the latter case the wake could exhibit a pronounced Mach cone structure. This physical mechanism could be important for the understanding of preliminary data from the PHENIX and STAR experiments at RHIC on the angular distribution of low-pt secondaries stemming from the away-side jet which indicate maxima at $\Delta\phi=\pi \pm 1.1$.Comment: Prepared for: Workshop on Correlations and Fluctuations in Relativistic Nuclear Collisions, MIT, Cambridge, Massachusetts, USA, 21-23 April 200

Exploring wind direction and SO2 concentration by circular-linear density estimation

The study of environmental problems usually requires the description of variables with different nature and the assessment of relations between them. In this work, an algorithm for flexible estimation of the joint density for a circular-linear variable is proposed. The method is applied for exploring the relation between wind direction and SO2 concentration in a monitoring station close to a power plant located in Galicia (NW-Spain), in order to compare the effectiveness of precautionary measures for pollutants reduction in two different years.Comment: 17 pages, 7 figures, 2 table

Shift invariant preduals of ℓ₁(ℤ)

The Banach space ℓ<sub>1</sub>(ℤ) admits many non-isomorphic preduals, for example, C(K) for any compact countable space K, along with many more exotic Banach spaces. In this paper, we impose an extra condition: the predual must make the bilateral shift on ℓ<sub>1</sub>(ℤ) weak<sup>*</sup>-continuous. This is equivalent to making the natural convolution multiplication on ℓ<sub>1</sub>(ℤ) separately weak*-continuous and so turning ℓ<sub>1</sub>(ℤ) into a dual Banach algebra. We call such preduals <i>shift-invariant</i>. It is known that the only shift-invariant predual arising from the standard duality between C<sub>0</sub>(K) (for countable locally compact K) and ℓ<sub>1</sub>(ℤ) is c<sub>0</sub>(ℤ). We provide an explicit construction of an uncountable family of distinct preduals which do make the bilateral shift weak<sup>*</sup>-continuous. Using Szlenk index arguments, we show that merely as Banach spaces, these are all isomorphic to c<sub>0</sub>. We then build some theory to study such preduals, showing that they arise from certain semigroup compactifications of ℤ. This allows us to produce a large number of other examples, including non-isometric preduals, and preduals which are not Banach space isomorphic to c<sub>0</sub>

A comparative study of Jet-quenching Schemes

The four major approximation schemes devised to study the modification of jets in dense matter are outlined. The comparisons are restricted to basic assumptions and approximations made in each case and the calculation methodology used. Emergent underlying similarities between apparently disparate methods brought about by the approximation schemes are exposed. Parameterizations of the medium in each scheme are discussed in terms of the transport coefficient $\hat{q}$. Discrepancies between the estimates obtained from the four schemes are discussed. Recent developments in the basic theory and phenomenology of energy loss are highlighted.Comment: 12 pages, 10 figures, latex, plenary presentation at the 19th International Conference on Ultra-Relativistic Nucleus-Nucleus Collisions (QM2006), Shanghai, China Nov. 14-20, 200

Improved catalytic activity of ruthenium–arene complexes in the reduction of NAD+

A series of neutral Ru-II half-sandwich complexes of the type [(eta(6)-arene)Ru(N,N')Cl] where the arene is para-cymene (p-cym), hexamethylbenzene (hmb), biphenyl (bip), or benzene (bn) and N,N' is N-(2-aminoethyl) -4-(trifluoromethyl)benzenesulfonamide (TfEn), N-(2-aminoethyl)-4-toluenesulfonamide (TsEn), or N-(2-aminoethyl)-methylenesulfonamide (MsEn) were synthesized and characterized. X-ray crystal structures of [(p-cym)Ru(MsEn)Cl] (1), [(hmb)Ru(TsEn)Cl] (5), [(hmb)Ru(TfEn)Cl] (6), [(bip)Ru(MsEn)Cl] (7), and [(bip)Ru(TsEn)Cl] (8) have been determined. The complexes can regioselectively catalyze the transfer hydrogenation of NAD(+) to give 1,4-NADH in the presence of formate. The turnover frequencies (TOF) when the arene is varied decrease in the order bn > bip > p-cym > hmb for complexes with the same N,N' chelating ligand. The TOF decreased with variation in the N,N' chelating ligand in the order TfEn > TsEn > MsEn for a given arene. [(bn)Ru(TfEn)Cl] (12) was the most active, with a TOP of 10.4 h(-1). The effects of NAD(+) and formate concentration on the reaction rates were determined for [(p-cym)Ru(TsEn)Cl] (2). Isotope studies implicated the formation of [(arene)Ru(N,N')(H)] as the rate-limiting step. The coordination of formate and subsequent CO2 elimination to generate the hydride were modeled computationally by density functional theory (DFT). CO2 elimination occurs via a two-step process with the coordinated formate first twisting to present its hydrogen toward the metal center. The computed barriers for CO2 release for arene = benzene follow the order MsEn > TsEn > TfEn, and for the Ms En system the barrier followed bn < hmb, both consistent with the observed rates. The effect of methanol on transfer hydrogenation rates in aqueous solution was investigated. A study of pH dependence of the reaction in D2O gave the optimum pH* as 7.2 with a TOF of 1.58 h(-1) for 2. The series of compounds reported here show an improvement in the catalytic activity by an order of magnitude compared to the ethylenediamine analogues

A comprehensive description of multiple observables in heavy-ion collisions at SPS

Combining and expanding on work from previous publications, a model for the evolution of ultrarelativistic heavy-ion collisions at the CERN SPS for 158 AGeV beam energy is presented. Based on the assumption of thermalization and a parametrization of the space-time expansion of the produced matter, this model is able to describe a large set of observables including hadronic momentum spectra, correlations and abundancies, the emission of real photons, dilepton radiation and the suppression pattern of charmonia. Each of these obervables provides unique capabilities to study the reaction dynamics and taken together they form a strong and consistent picture of the evolving system. Based on the emission of hard photons, we argue that a strongly interacting, hot and dense system with temperatures above 250 MeV has to be created early in the reaction. Such a system is bound to be different from hadronic matter and likely to be a quark-gluon plasma, and we find that this assumption is in line with the subsequent evolution of the system that is reflected in other observables.Comment: 21 pages, 10 figures, submitted to J. Phys.

Mach Cones in Quark Gluon Plasma

The experimental azimuthal dihadron distributions at RHIC show a double peak structure in the away side ($\Delta \phi = \pi \pm 1.2$ rad.) for intermediate $p_t$ particles. A variety of models have appeared trying to describe this modification. We will review most of them, with special emphasis in the Conical Flow scenario in which the observed shape is a consequence of the emission of sound by a supersonic high momentum particle propagating in the Quark Gluon Plasma.Comment: 8 pages, 3 figures, Invited plenary talk given at the 19th International Conference on Ultrarelativistic Nucleus-Nucleus Collisions: Quark Matter 2006 (QM 2006), Shanghai, China, 14-20 Nov 200

Qualitative Robustness of Bootstrap Approximations for Kernel Based Methods

status: publishe

Hadronic observables from SIS to SPS energies - anything strange with strangeness ?

We calculate $p, \pi^\pm, K^\pm$ and $\Lambda$(+$\Sigma^0$) rapidity distributions and compare to experimental data from SIS to SPS energies within the UrQMD and HSD transport approaches that are both based on string, quark, diquark ($q, \bar{q}, qq, \bar{q}\bar{q}$) and hadronic degrees of freedom. The two transport models do not include any explicit phase transition to a quark-gluon plasma (QGP). It is found that both approaches agree rather well with each other and with the experimental rapidity distributions for protons, $\Lambda$'s, $\pi^\pm$ and $K^\pm$. Inspite of this apparent agreement both transport models fail to reproduce the maximum in the excitation function for the ratio $K^+/\pi^+$ found experimentally between 11 and 40 A$\cdot$GeV. A comparison to the various experimental data shows that this 'failure' is dominantly due to an insufficient description of pion rapidity distributions rather than missing 'strangeness'. The modest differences in the transport model results -- on the other hand -- can be attributed to different implementations of string formation and fragmentation, that are not sufficiently controlled by experimental data for the 'elementary' reactions in vacuum.Comment: 46 pages, including 15 eps figures, to be published in Phys. Rev.

Efficacy and safety of the anti-IL-12/23 p40 monoclonal antibody, ustekinumab, in patients with active psoriatic arthritis despite conventional non-biological and biological anti-tumour necrosis factor therapy: 6-month and 1-year results of the phase 3, multicentre, double-blind, placebo-controlled, randomised PSUMMIT 2 trial

Objective: Assess ustekinumab efficacy (week 24/week 52) and safety (week 16/week 24/week 60) in patients with active psoriatic arthritis (PsA) despite treatment with conventional and/or biological anti-tumour necrosis factor (TNF) agents. Methods: In this phase 3, multicentre, placebo-controlled trial, 312 adults with active PsA were randomised (stratified by site, weight (&#8804;100 kg/&#62;100 kg), methotrexate use) to ustekinumab 45 mg or 90 mg at week 0, week 4, q12 weeks or placebo at week 0, week 4, week 16 and crossover to ustekinumab 45 mg at week 24, week 28 and week 40. At week 16, patients with &#60;5% improvement in tender/swollen joint counts entered blinded early escape (placebo→45 mg, 45 mg→90 mg, 90 mg→90 mg). The primary endpoint was &#8805;20% improvement in American College of Rheumatology (ACR20) criteria at week 24. Secondary endpoints included week 24 Health Assessment Questionnaire-Disability Index (HAQ-DI) improvement, ACR50, ACR70 and &#8805;75% improvement in Psoriasis Area and Severity Index (PASI75). Efficacy was assessed in all patients, anti-TNF-naïve (n=132) patients and anti-TNF-experienced (n=180) patients. Results: More ustekinumab-treated (43.8% combined) than placebo-treated (20.2%) patients achieved ACR20 at week 24 (p&#60;0.001). Significant treatment differences were observed for week 24 HAQ-DI improvement (p&#60;0.001), ACR50 (p&#8804;0.05) and PASI75 (p&#60;0.001); all benefits were sustained through week 52. Among patients previously treated with &#8805;1 TNF inhibitor, sustained ustekinumab efficacy was also observed (week 24 combined vs placebo: ACR20 35.6% vs 14.5%, PASI75 47.1% vs 2.0%, median HAQ-DI change −0.13 vs 0.0; week 52 ustekinumab-treated: ACR20 38.9%, PASI75 43.4%, median HAQ-DI change −0.13). No unexpected adverse events were observed through week 60. Conclusions: The interleukin-12/23 inhibitor ustekinumab (45/90 mg q12 weeks) yielded significant and sustained improvements in PsA signs/symptoms in a diverse population of patients with active PsA, including anti-TNF-experienced PsA patients