297,067 research outputs found

    Simplifying the mosaic description of DNA sequences

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    By using the Jensen-Shannon divergence, genomic DNA can be divided into compositionally distinct domains through a standard recursive segmentation procedure. Each domain, while significantly different from its neighbours, may however share compositional similarity with one or more distant (non--neighbouring) domains. We thus obtain a coarse--grained description of the given DNA string in terms of a smaller set of distinct domain labels. This yields a minimal domain description of a given DNA sequence, significantly reducing its organizational complexity. This procedure gives a new means of evaluating genomic complexity as one examines organisms ranging from bacteria to human. The mosaic organization of DNA sequences could have originated from the insertion of fragments of one genome (the parasite) inside another (the host), and we present numerical experiments that are suggestive of this scenario.Comment: 16 pages, 1 figure, Accepted for publication in Phys. Rev.

    Rectifying "nanohomo" contacts of W-Ga-C composite pad and nanowire fabricated by focused-ion-beam induced chemical vapour deposition

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    We prepared W-Ga-C composite contacts on W-Ga-C composite nanowires by focused-ion-beam-induced chemical vapor deposition using a dual-beam scanning electron microscope/focused-ion-beam system. The current-voltage (I-V) characteristics of wires were found to change from nonlinear to linear with increasing wire thickness. For wires with small dimensions, which result in strong nonlinear I-V behavior at room temperature, pairs of contacts were fabricated along the wire under different ion energies and scanning modes. Nonlinear and asymmetric rectifying I-V characteristics were observed. The results suggest that nanoscaled W-Ga-C nanowires may behave similarly to semiconductors and that the contact characteristics may be modified using different deposition conditions. Furthermore, ohmiclike junctions could be formed through the use of specific deposition conditions for the contact pads and nanowires

    Status Quo Analysis of the Flathead River Conflict

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    Status quo analysis algorithms developed within the paradigm of the graph model for conflict resolution are applied to an international river basin conflict involving the United States and Canada to assess the likeliness of various compromise resolutions. The conflict arose because the state of Montana feared that further expansion of the Sage Creek Coal Company facilities in Canada would pollute the Flathead River, which flows from British Columbia into Montana. Significant insights not generally available from a static stability analysis are obtained about potential resolutions of the conflict under study and about how decision makers’ interactions may direct the conflict to distinct resolutions. Analyses also show how political considerations may affect a particular decision maker’s choice, thereby influencing the evolution of the conflict
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