pH and acid phosphatase determinations after growth of Aspergillus nidulans on solid medium

pH and acid phosphatase determinations after growth of Aspergillus nidulans on solid mediu

The levels of mRNA expressed by gene palF of A. nidulans do not appear to be pH regulated

Although pal genes are putative members of a signaling cascade involved in ambient pH sensing and in the consecutive activation of PacC protein, recent findings show that most of them (palA, B, C, H and I) do not respond to ambient pH at the transcriptional level. Here, we show that mRNA levels of the remainding palF gene are also constant at various growth pH values

Chiral Fermions on the Lattice

An expression for the lattice effective action induced by chiral fermions in any even dimensions in terms of an overlap of two states is shown to have promising properties in two dimensions: The correct abelian anomaly is reproduced and instantons are suppressed.Comment: 9p, Postscript file, RU--93--3

Presynaptic partner selection during retinal circuit reassembly varies with timing of neuronal regeneration in vivo

Whether neurons can restore their original connectivity patterns during circuit repair is unclear. Taking advantage of the regenerative capacity of zebrafish retina, we show here the remarkable specificity by which surviving neurons reassemble their connectivity upon regeneration of their major input. H3 horizontal cells (HCs) normally avoid red and green cones, and prefer ultraviolet over blue cones. Upon ablation of the major (ultraviolet) input, H3 HCs do not immediately increase connectivity with other cone types. Instead, H3 dendrites retract and re-extend to contact new ultraviolet cones. But, if regeneration is delayed or absent, blue-cone synaptogenesis increases and ectopic synapses are made with red and green cones. Thus, cues directing synapse specificity can be maintained following input loss, but only within a limited time period. Further, we postulate that signals from the major input that shape the H3 HC's wiring pattern during development persist to restrict miswiring after damage

Toward a global description of the nucleus-nucleus interaction

Extensive systematization of theoretical and experimental nuclear densities and of optical potential strengths exctracted from heavy-ion elastic scattering data analyses at low and intermediate energies are presented.The energy-dependence of the nuclear potential is accounted for within a model based on the nonlocal nature of the interaction.The systematics indicate that the heavy-ion nuclear potential can be described in a simple global way through a double-folding shape,which basically depends only on the density of nucleons of the partners in the collision.The poissibility of extracting information about the nucleon-nucleon interaction from the heavy-ion potential is investigated.Comment: 12 pages,12 figure

Soft Photons in Hadron-Hadron Collisions: Synchrotron Radiation from the QCD Vacuum?

We discuss the production of soft photons in high energy hadron-hadron collisions. We present a model where quarks and antiquarks in the hadrons emit ``synchrotron light'' when being deflected by the chromomagnetic fields of the QCD vacuum, which we assume to have a nonperturbative structure. This gives a source of prompt soft photons with frequencies $\omega <= 300 MeV$ in the c.m. system of the collision in addition to hadronic bremsstrahlung. In comparing the frequency spectrum and rate of ``synchrotron'' photons to experimental results we find some supporting evidence for their existence. We make an exclusive--inclusive connection argument to deduce from the ``synchrotron'' effect a behaviour of the neutron electric formfactor $G_E^n(Q^2)$ proportional to $(Q^2)^{1/6}$ for $Q^2 < 20 fm^{-2}$. We find this to be consistent with available data. In our view, soft photon production in high energy hadron-hadron and lepton-hadron collisions as well as the behaviour of electromagnetic hadron formfactors for low $Q^2$ are thus sensitive probes of the nonperturbative structure of the QCD vacuum.Comment: Heidelberg preprint HD-THEP-94-36, 31 pages, LaTeX + ZJCITE.sty (included), 12 figures appended as uuencoded compressed ps-fil

ERP evidence suggests executive dysfunction in ecstasy polydrug users

Background: Deficits in executive functions such as access to semantic/long-term memory have been shown in ecstasy users in previous research. Equally, there have been many reports of equivocal findings in this area. The current study sought to further investigate behavioural and electro-physiological measures of this executive function in ecstasy users. Method: Twenty ecstasy–polydrug users, 20 non-ecstasy–polydrug users and 20 drug-naïve controls were recruited. Participants completed background questionnaires about their drug use, sleep quality, fluid intelligence and mood state. Each individual also completed a semantic retrieval task whilst 64 channel Electroencephalography (EEG) measures were recorded. Results: Analysis of Variance (ANOVA) revealed no between-group differences in behavioural performance on the task. Mixed ANOVA on event-related potential (ERP) components P2, N2 and P3 revealed significant between-group differences in the N2 component. Subsequent exploratory univariate ANOVAs on the N2 component revealed marginally significant between-group differences, generally showing greater negativity at occipito-parietal electrodes in ecstasy users compared to drug-naïve controls. Despite absence of behavioural differences, differences in N2 magnitude are evidence of abnormal executive functioning in ecstasy–polydrug users