1,822 research outputs found
Water Transport in Onion (Allium cepa L.) Roots (Changes of Axial and Radial Hydraulic Conductivities during Root Development)
Theory of pixel lensing towards M31 I: the density contribution and mass of MACHOs
POINT-AGAPE is an Anglo-French collaboration which is employing the Isaac
Newton Telescope (INT) to conduct a pixel-lensing survey towards M31. In this
paper we investigate what we can learn from pixel-lensing observables about the
MACHO mass and fractional contribution in M31 and the Galaxy for the case of
spherically-symmetric near-isothermal haloes. We employ detailed pixel-lensing
simulations which include many of the factors which affect the observables. For
a maximum MACHO halo we predict an event rate in V of up to 100 per season for
M31 and 40 per season for the Galaxy. However, the Einstein radius crossing
time is generally not measurable and the observed full-width half-maximum
duration provides only a weak tracer of lens mass. Nonetheless, we find that
the near-far asymmetry in the spatial distribution of M31 MACHOs provides
significant information on their mass and density contribution. We present a
likelihood estimator for measuring the fractional contribution and mass of both
M31 and Galaxy MACHOs which permits an unbiased determination to be made of
MACHO parameters, even from data-sets strongly contaminated by variable stars.
If M31 does not have a significant population of MACHOs in the mass range
0.001-1 Solar masses strong limits will result from the first season of INT
observations. Simulations based on currently favoured density and mass values
indicate that, after three seasons, the M31 MACHO parameters should be
constrained to within a factor four uncertainty in halo fraction and an order
of magnitude uncertainty in mass (90% confidence). Interesting constraints on
Galaxy MACHOs may also be possible. For a campaign lasting ten years,
comparable to the lifetime of current LMC surveys, reliable estimates of MACHO
parameters in both galaxies should be possible. (Abridged)Comment: 21 pages, 14 figures. Submitted to MNRA
Stratigraphy and age of the Eocene Igtertivâ Formation basalts, alkaline pebbles and sediments of the Kap Dalton Group in the graben at Kap Dalton, East Greenland
Characterization of a POROS\u3csup\u3eTM\u3c/sup\u3e-fumonisin B1 Affinity Column for Isolating Ceramide Synthase from Rat Liver
Fumonisin B1 is a mycotoxin produced by fungi of the genus Fusarium, common pathogens of corn and other grain plants. Toxic effects associated with fumonisin B1 include equine leukoencephalomacia, porcine pulmonary edema, rat renal carcinoma, and murine hepatocellular carcinoma. Increased risk for esophageal cancer in humans has been epidemiologically associated with consumption of corn contaminated with Fusarium, suggesting that fumonisin B1 may be involved. The biological effects of fumonisin B1 exposure result primarily from disruption of de novo sphingolipid biosynthesis via inhibition of ceramide synthase. Exposure of animals or cultured cells to fumonisin B1 results in the characteristic accumulation of sphinganine, a toxic sphingolipid intermediate, concomitant with depletion of essential complex sphingolipids. Ceramide synthase has not been purified to homogeniety and characterized. We prepared crude ceramide synthase from detergent-extracted rat liver homogenates using PEG-precipitation and cation exchange chromatography. Ceramide synthase activity was then sequestered, using fumonisin B1 covalently coupled to POROS-NH particles, and eluted selectively. The observed 119-fold enrichment in specific activity demonstrates the utility of fumonisin-POROS affinity chromatography in the purification of ceramide synthase
Ultrafast all-optical demultiplexer based on monolithic Mach-Zehnder interferometer with integrated semiconductor optical amplifiers
A monolithically integrated and fully packaged Mach-Zehnder interferometer with semiconductor optical amplifiers (MZI-SOA) is demonstrated as polarisation-independent high-speed demultiplexer for up to 160 Gbit/s optical time division multiplexed (OTDM) data stream
A monoclinic polymorph of N-ethoxycarbonyl-N′-(3-phenyl-1H-1,2,4-triazol-5-yl)thiourea
The title compound, C12H13N5O2S {systematic name: ethyl N-[N-(3-phenyl-1H-1,2,4-triazol-5-yl)carbamothioyl]carbamate}, is a monoclinic polymorph (space group P21/c) which crystallizes with three similar independent molecules in the asymmetric unit. The triazole ring makes dihedral angles of 6.6 (2), 8.4 (2) and 10.6 (2)° with the phenyl ring in the three independent molecules. The structure was previously reported [Dolzhenko et al. (2010a
▶). Acta Cryst., E46, o425] as a triclinic polymorph crystallizing in space group P
. Molecules in both polymorphs possess two S(6) rings generated by intramolecular N—H⋯S and N—H⋯O hydrogen bonds, resulting in similar molecular geometries. However, the two polymorphs differ in the crystal packing. In contrast to the dimers of the triclinic polymorph, molecules of the monoclinic polymorph are connected by intermolecular N—H⋯S and N—H⋯N hydrogen bonds, forming pseudosymmetric trimers arranged in sheets parallel to (302)
Signals for Lorentz Violation in Post-Newtonian Gravity
The pure-gravity sector of the minimal Standard-Model Extension is studied in
the limit of Riemann spacetime. A method is developed to extract the modified
Einstein field equations in the limit of small metric fluctuations about the
Minkowski vacuum, while allowing for the dynamics of the 20 independent
coefficients for Lorentz violation. The linearized effective equations are
solved to obtain the post-newtonian metric. The corresponding post-newtonian
behavior of a perfect fluid is studied and applied to the gravitating many-body
system. Illustrative examples of the methodology are provided using bumblebee
models. The implications of the general theoretical results are studied for a
variety of existing and proposed gravitational experiments, including lunar and
satellite laser ranging, laboratory experiments with gravimeters and torsion
pendula, measurements of the spin precession of orbiting gyroscopes, timing
studies of signals from binary pulsars, and the classic tests involving the
perihelion precession and the time delay of light. For each type of experiment
considered, estimates of the attainable sensitivities are provided. Numerous
effects of local Lorentz violation can be studied in existing or near-future
experiments at sensitivities ranging from parts in 10^4 down to parts in
10^{15}.Comment: 46 pages two-column REVTeX, accepted in Physical Review
Alterations of adiponectin gene expression and DNA methylation in adipose tissues and blood cells are associated with gestational diabetes and neonatal outcome
BACKGROUND: Adiponectin critically contributes to metabolic homeostasis, especially by insulin-sensitizing action. Gestational diabetes mellitus (GDM) is characterized by insulin resistance leading to materno-fetal hyperglycemia and detrimental birth outcomes. By investigating paired subcutaneous (SAT) and visceral adipose tissue (VAT) as well as blood (cell) samples of GDM-affected (n = 25) vs. matched control (n = 30) mother-child dyads of the prospective "EaCH" cohort study, we addressed whether alterations of adiponectin plasma, mRNA, and DNA methylation levels are associated with GDM and offspring characteristics.
RESULTS: Hypoadiponectinemia was present in women with GDM, even after adjustment for body mass index (BMI). This was accompanied by significantly decreased mRNA levels in both SAT and VAT (P < 0.05), independent of BMI. Maternal plasma adiponectin showed inverse relations with glucose and homeostatic model assessment of insulin resistance (both P < 0.01). In parallel to reduced mRNA expression in GDM, significant (P < 0.05) yet small alterations in locus-specific DNA methylation were observed in maternal fat (~ 2%) and blood cells (~ 1%). While newborn adiponectin levels were similar between groups, DNA methylation in GDM offspring was variously altered (~ 1-4%; P < 0.05).
CONCLUSIONS: Reduced adiponectin seems to be a pathogenic co-factor in GDM, even independent of BMI, affecting materno-fetal metabolism. While altered maternal DNA methylation patterns appear rather marginally involved, functional, diagnostic, and/or predictive implications of cord blood DNA methylation should be further evaluated
Lines, Circles, Planes and Spheres
Let be a set of points in , no three collinear and not
all coplanar. If at most are coplanar and is sufficiently large, the
total number of planes determined is at least . For similar conditions and
sufficiently large , (inspired by the work of P. D. T. A. Elliott in
\cite{Ell67}) we also show that the number of spheres determined by points
is at least , and this bound is best
possible under its hypothesis. (By , we are denoting the
maximum number of three-point lines attainable by a configuration of
points, no four collinear, in the plane, i.e., the classic Orchard Problem.)
New lower bounds are also given for both lines and circles.Comment: 37 page
Individual scatterers as microscopic origin of equilibration between spin- polarized edge channels in the quantum Hall regime
The equilibration length between spin-polarized edge states in the Quantum
Hall regime is measured as a function of a gate voltage applied to an electrode
on top of the edge channels. Reproducible fluctuations in the coupling are
observed and interpreted as a mesoscopic fingerprint of single spin-flip
scatterers which are turned on and off. A model to analyze macroscopic edge
state coupling in terms of individual scatterers is developed, and
characteristic values for these scatterers in our samples are extracted. For
all samples investigated, the distance between spin-flip scatterers lies
between the Drude and the quantum scattering length.Comment: 4 pages, 2 figure
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