37 research outputs found

    Black Populations and Economic Growth: An Extreme Bounds Analysis of Mississippi County-Level Data

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    We use Mississippi county-level data on (per capita) income and the percentages of populations that are Black (henceforth "Black") to examine the relationship between race and economic growth. The analysis is also conditioned on 40 other economic and socio-demographic variables. Given a negative and statistically significant partial correlation between income growth and Black, we ask if it is robust to exhaustive combinations of other conditioning variables (taken 3 at a time). The evidence suggests yes. Since even robust correlation does not imply causation, we then ask if other robust correlates with income growth play a roll in accounting for Black in the data. The answer “yes” is obtained for only one other robust correlate of the "right" sign: the percentage of a population that is below the poverty level

    Aurora A depletion reveals centrosome-independent polarization mechanism in Caenorhabditis elegans

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    How living systems break symmetry in an organized manner is a fundamental question in biology. In wild-type Caenorhabditis elegans zygotes, symmetry breaking during anterior-posterior axis specification is guided by centrosomes, resulting in anterior-directed cortical flows and a single posterior PAR-2 domain. We uncover that C. elegans zygotes depleted of the Aurora A kinase AIR-1 or lacking centrosomes entirely usually establish two posterior PAR-2 domains, one at each pole. We demonstrate that AIR-1 prevents symmetry breaking early in the cell cycle, whereas centrosomal AIR-1 instructs polarity initiation thereafter. Using triangular microfabricated chambers, we establish that bipolarity of air-1(RNAi) embryos occurs effectively in a cell-shape and curvature-dependent manner. Furthermore, we develop an integrated physical description of symmetry breaking, wherein local PAR-2-dependent weakening of the actin cortex, together with mutual inhibition of anterior and posterior PAR proteins, provides a mechanism for spontaneous symmetry breaking without centrosomes

    DLF Privacy and Ethics in Technology Working Group

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    More information about the Working Group can be found here: https://wiki.diglib.org/Technologies_of_Surveillanc
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