Inhibition of Protease Activity in Muscle Extracts and Surimi from Pacific Whiting, Merluccius productus, and Arrowtooth Flounder, Atheresthes stomias

Muscle extracts of Pacific whiting, Merluccius productus, and arrowtooth flounder, Atheresthes stomias, were assayed for proteolytic activity using azocasein as a substrate. Pacific whiting extracts showed maximum activity at pH 5.0-5.2 and a temperature of 50°C, while arrowtooth flounder extracts had maximum activity at pH 5.5 and 55°C. Three sources of inhibitors (potatoes, egg white, beef plasma protein) were evaluated in vitro for inhibition of protease activity. All three were found to be effective inhibitors in crude muscle extracts. Further studies utilizing these inhibitors in surimi showed that potato was equivalent to both egg white and beef plasma protein in preserving the gel forming characteristics ofheated kamaboko in both species

Production of massive stable particles in inflaton decay

We point out that inflaton decays can be a copious source of stable or long--lived particles $\chi$ with mass exceeding the reheat temperature $T_R$. Once higher order processes are included, this statement is true for any $\chi$ particle with renormalizable (gauge or Yukawa) interactions. This contribution to the $\chi$ density often exceeds the contribution from thermal $\chi$ production, leading to significantly stronger constraints on model parameters than those resulting from thermal $\chi$ production alone. For example, we all but exclude models containing stable charged particles with mass less than half the mass of the inflaton.Comment: 4 revtex pages, 1 figure (uses axodraw). Slightly modified for better clarification, few changes in references. Final verssion published in Phys. Rev. Let

Drastic enhancement of magnon thermal conductivity in the Bose-Einstein condensed state of TlCuCl3_3

We have measured the thermal conductivity of a TlCuCl$_3$ single crystal in magnetic fields up to 14 T. It has been found that the temperature dependence of the thermal conductivity exhibits a sharp peak at 4 K in zero field, which is suppressed by the application of magnetic fields up to 7 T. The peak is concluded to be attributable to the enhancement of the thermal conductivity due to phonons because of the formation of a spin-gap state. In high magnetic fields above 7 T, on the other hand, another sharp peak appears around 4 K and this is enhanced with increasing magnetic field. This peak is regarded as being attributable to the enhancement of the thermal conductivity due to magnons and/or phonons because of the drastic extension of the mean free path of magnons and/or phonons in the Bose-Einstein condensed state.Comment: 4 pages, 4 figure

Thermal conductivity of anisotropic and frustrated spin-1/2 chains

We analyze the thermal conductivity of anisotropic and frustrated spin-1/2 chains using analytical and numerical techniques. This includes mean-field theory based on the Jordan-Wigner transformation, bosonization, and exact diagonalization of systems with N<=18 sites. We present results for the temperature dependence of the zero-frequency weight of the conductivity for several values of the anisotropy \Delta. In the gapless regime, we show that the mean-field theory compares well to known results and that the low-temperature limit is correctly described by bosonization. In the antiferromagnetic and ferromagnetic gapped regime, we analyze the temperature dependence of the thermal conductivity numerically. The convergence of the finite-size data is remarkably good in the ferromagnetic case. Finally, we apply our numerical method and mean-field theory to the frustrated chain where we find a good agreement of these two approaches on finite systems. Our numerical data do not yield evidence for a diverging thermal conductivity in the thermodynamic limit in case of the antiferromagnetic gapped regime of the frustrated chain.Comment: 4 pages REVTeX4 including 6 figures; published version, main modification: added emphasis that the data of our Fig. 3 point to a vanishing of the thermal Drude weight in the thermodynamic limit in this cas

Techniques for Studying Decoding of Single Cell Dynamics

Cells must be able to interpret signals they encounter and reliably generate an appropriate response. It has long been known that the dynamics of transcription factor and kinase activation can play a crucial role in selecting an individual cell's response. The study of cellular dynamics has expanded dramatically in the last few years, with dynamics being discovered in novel pathways, new insights being revealed about the importance of dynamics, and technological improvements increasing the throughput and capabilities of single cell measurements. In this review, we highlight the important developments in this field, with a focus on the methods used to make new discoveries. We also include a discussion on improvements in methods for engineering and measuring single cell dynamics and responses. Finally, we will briefly highlight some of the many challenges and avenues of research that are still open

The Role of Lattice Coupling in Establishing Electronic and Magnetic Properties in Quasi-One-Dimensional Cuprates

High resolution resonant inelastic x-ray scattering has been performed to reveal the role of lattice-coupling in a family of quasi-1D insulating cuprates, Ca$_{2+5x}$Y$_{2-5x}$Cu$_5$O$_{10}$. Site-dependent low energy excitations arising from progressive emissions of a 70 meV lattice vibrational mode are resolved for the first time, providing a direct measurement of electron-lattice coupling strength. We show that such electron-lattice coupling causes doping-dependent distortions of the Cu-O-Cu bond angle, which sets the intra-chain spin exchange interactions. Our results indicate that the lattice degrees of freedom are fully integrated into the electronic behavior in low dimensional systems.Comment: 5 pages, 4 figur

Non-dissipative thermal transport in the massive regimes of the XXZ chain

We present exact results on the thermal conductivity of the one-dimensional spin-1/2 XXZ model in the massive antiferromagnetic and ferromagnetic regimes. The thermal Drude weight is calculated by a lattice path integral formulation. Numerical results for wide ranges of temperature and anisotropy as well as analytical results in the low and high temperature limits are presented. At finite temperature, the thermal Drude weight is finite and hence there is non-dissipative thermal transport even in the massive regime. At low temperature, the thermal Drude weight behaves as $D(T)\sim \exp(-\delta/T)/\sqrt{T}$ where $\delta$ is the one-spinon (respectively one-magnon) excitation energy for the antiferromagnetic (respectively ferromagnetic) regime.Comment: 16 page

Conformational spread as a mechanism for cooperativity in the bacterial flagellar switch

The bacterial flagellar switch that controls the direction of flagellar rotation during chemotaxis has a highly cooperative response. This has previously been understood in terms of the classic two-state, concerted model of allosteric regulation. Here, we used high-resolution optical microscopy to observe switching of single motors and uncover the stochastic multistate nature of the switch. Our observations are in detailed quantitative agreement with a recent general model of allosteric cooperativity that exhibits conformational spread—the stochastic growth and shrinkage of domains of adjacent subunits sharing a particular conformational state. We expect that conformational spread will be important in explaining cooperativity in other large signaling complexes