864 research outputs found
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Microwave Analysis of the Damped Detuned Accelerator Structure
Damped and detuned accelerating structures (DDS), designed to minimize the effects of long range wakefields excited by bunchtrains, are presently under investigations at SLAC. The authors report the first studies of beam-induced microwave signals in a prototype DDS. The DDS is a 206 cell, nearly constant gradient structure, employing Gaussian detuning, and four symmetrically placed waveguide manifolds to damp the first-band dipole modes. They describe the manifold and output coupler design, bench measurements, and measurements with beam during the ASSET experiment. Dipole mode signals have been used to steer the beam to the structure center and minimize the wakefield kick
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1.2 MW klystron for Asymmetric Storage Ring B Factory
A cw klystron operating at 476 MHz has been developed jointly by SLAC and Varian Associates. The unique set of characteristics of this tube were strongly guided by requirements of the fast feedback necessary to prevent oscillations of the storage ring beams caused by the detuned accelerating cavity. This requires a combination of bandwidth and short group delay within the klystron. The RF feedback stabilization scheme also requires amplitude modulation making it necessary to operate the klystron about 10% below saturation. Performance specifications and initial operating results are presented
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RF breakdown studies in X-Band klystron cavities
RF breakdown studies are presently being carried out at SLAC with klystron cavities in a traveling wave resonator (TWR). Different kinds of fabrication methods and several kinds of semiconducting and insulating coatings have been applied to X-Band TM{sub 010} cavities. RF breakdown thresholds up to 250 MV/m have been obtained. Dark current levels were found to be depressed on TiN-coated and single-point diamond turned cavities. A new TM{sub 020} cavity with demountable electrodes has been designed and will be used to test a variety of materials, coatings, and processes. Recent tests of klystron output windows at 119 MW are also presented in this paper
Wetting and bonding characteristics of selected liquid-metals with a high power diode laser treated alumina bioceramic
Changes in the wettability characteristics of an alumina bioceramic occasioned by high power diode laser (HPDL) surface treatment were apparent from the observed reduction in the contact angle. Such changes were due to the HPDL bringing about reductions the surface roughness, increases in the surface O2 content and increases in the polar component of the surface energy. Additionally, HPDL treatment of the alumina bioceramic surface was found to effect an improvement in the bonding characteristics by increasing the work of adhesion. An electronic approach was used to elucidate the bonding characteristics of the alumina bioceramic before and after HPDL treatment. It is postulated that HPDL induced changes to the alumina bioceramic produced a surface with a reduced bandgap energy which consequently increased the work of adhesion by increasing the electron transfer at the metal/oxide interface and thus the metal-oxide interactions. Furthermore, it is suggested that the increase in the work of adhesion of the alumina bioceramic after HPDL treatment was due to a correlation existing between the wettability and ionicity of the alumina bioceramic; for it is believed that the HPDL treated surface is less ionic in nature than the untreated surface and therefore exhibits better wettability characteristics
The relationship between aortic wall distensibility and rupture of infrarenal abdominal aortic aneurysm
AbstractObjective: A more accurate means of prediction of abdominal aortic aneurysm (AAA) rupture would improve the clinical and cost effectiveness of prophylactic repair. The purpose of this study was to determine whether AAA wall distensibility can be used to predict time to rupture independently of other recognized risk factors. Methods: A prospective, six-center study of 210 patients with AAA in whom blood pressure (BP), maximum AAA diameter (Dmax), and AAA distensibility (pressure strain elastic modulus [Ep] and stiffness [β]) were measured at 6 months with an ultrasound scan-based echo-tracking technique. A stepwise, time-dependent, Cox proportional hazards model was used to determine the effect on time to rupture of age, gender, BP, Dmax, BP, Ep, β, and change in Dmax, Ep, and β adjusted for time between follow-up visits. Results: Median (interquartile range) AAA diameter was 48 mm (41 to 54 mm), median age was 72 years (68 to 77 years), and median follow-up period was 19 months (9 to 30 months). In the Cox model, female gender (hazards ratio [HR], 2.78; 95% CI, 1.23 to 6.28; P =.014), larger Dmax (HR, 1.36 for 10% increase in Dmax; 95% CI, 1.12 to 1.66; P =.002), higher diastolic BP (HR, 1.13 for 10% increase in BP; 95% CI, 1.13 to 1.92; P =.004), and a decrease in Ep (increase in distensibility) over time (HR, 1.38 for 10% decrease in Ep over 6 months; 95% CI, 1.08 to 1.78; P =.010) significantly reduced the time to rupture (had a shorter time to rupture). Conclusion: Women have a shorter time to AAA rupture. The measurement of AAA distensibility, diastolic BP, and diameter may provide a more accurate assessment of rupture risk than diameter alone. (J Vasc Surg 2003;37:112-7.
Modeling Micro-Porous Surfaces for Secondary Electron Emission Control to Suppress Multipactor
This work seeks to understand how the topography of a surface can be engineered to control secondary electron emission (SEE) for multipactor suppression. Two unique, semi-empirical models for the secondary electron yield (SEY) of a micro-porous surface are derived and compared. The first model is based on a two-dimensional (2D) pore geometry. The second model is based on a three-dimensional (3D) pore geometry. The SEY of both models is shown to depend on two categories of surface parameters: chemistry and topography. An important parameter in these models is the probability of electron emissions to escape the surface pores. This probability is shown by both models to depend exclusively on the aspect ratio of the pore (the ratio of the pore height to the pore diameter). The increased accuracy of the 3D model (compared to the 2D model) results in lower electron escape probabilities with the greatest reductions occurring for aspect ratios less than two. In order to validate these models, a variety of micro-porous gold surfaces were designed and fabricated using photolithography and electroplating processes. The use of an additive metal-deposition process (instead of the more commonly used subtractive metal-etch process) provided geometrically ideal pores which were necessary to accurately assess the 2D and 3D models. Comparison of the experimentally measured SEY data with model predictions from both the 2D and 3D models illustrates the improved accuracy of the 3D model. For a micro-porous gold surface consisting of pores with aspect ratios of two and a 50% pore density, the 3D model predicts that the maximum total SEY will be one. This provides optimal engineered surface design objectives to pursue for multipactor suppression using gold surfaces
The relationship between aortic wall distensibility and rupture of infrarenal abdominal aortic aneurysm
AbstractObjective: A more accurate means of prediction of abdominal aortic aneurysm (AAA) rupture would improve the clinical and cost effectiveness of prophylactic repair. The purpose of this study was to determine whether AAA wall distensibility can be used to predict time to rupture independently of other recognized risk factors. Methods: A prospective, six-center study of 210 patients with AAA in whom blood pressure (BP), maximum AAA diameter (Dmax), and AAA distensibility (pressure strain elastic modulus [Ep] and stiffness [β]) were measured at 6 months with an ultrasound scan-based echo-tracking technique. A stepwise, time-dependent, Cox proportional hazards model was used to determine the effect on time to rupture of age, gender, BP, Dmax, BP, Ep, β, and change in Dmax, Ep, and β adjusted for time between follow-up visits. Results: Median (interquartile range) AAA diameter was 48 mm (41 to 54 mm), median age was 72 years (68 to 77 years), and median follow-up period was 19 months (9 to 30 months). In the Cox model, female gender (hazards ratio [HR], 2.78; 95% CI, 1.23 to 6.28; P =.014), larger Dmax (HR, 1.36 for 10% increase in Dmax; 95% CI, 1.12 to 1.66; P =.002), higher diastolic BP (HR, 1.13 for 10% increase in BP; 95% CI, 1.13 to 1.92; P =.004), and a decrease in Ep (increase in distensibility) over time (HR, 1.38 for 10% decrease in Ep over 6 months; 95% CI, 1.08 to 1.78; P =.010) significantly reduced the time to rupture (had a shorter time to rupture). Conclusion: Women have a shorter time to AAA rupture. The measurement of AAA distensibility, diastolic BP, and diameter may provide a more accurate assessment of rupture risk than diameter alone. (J Vasc Surg 2003;37:112-7.
Individual variation in levels of haptoglobin-related protein in children from Gabon
Background: Haptoglobin related protein (Hpr) is a key component of trypanosome lytic factors (TLF), a subset of highdensity lipoproteins (HDL) that form the first line of human defence against African trypanosomes. Hpr, like haptoglobin (Hp) can bind to hemoglobin (Hb) and it is the Hpr-Hb complexes which bind to these parasites allowing uptake of TLF. This unique form of innate immunity is primate-specific. To date, there have been no population studies of plasma levels of Hpr, particularly in relation to hemolysis and a high prevalence of ahaptoglobinemia as found in malaria endemic areas. Methods and Principal Findings: We developed a specific enzyme-linked immunosorbent assay to measure levels of plasma Hpr in Gabonese children sampled during a period of seasonal malaria transmission when acute phase responses (APR), malaria infection and associated hemolysis were prevalent. Median Hpr concentration was 0.28 mg/ml (range 0.03-1.1). This was 5-fold higher than that found in Caucasian children (0.049 mg/ml, range 0.002-0.26) with no evidence of an APR. A general linear model was used to investigate associations between Hpr levels, host polymorphisms, parasitological factors and the acute phase proteins, Hp, C-reactive protein (CRP) and albumin. Levels of Hpr were associated with Hp genotype, decreased with age and were higher in females. Hpr concentration was strongly correlated with that of Hp, but not CRP
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