515 research outputs found
Defining an age cut-off for older offenders: a systematic review of literature
PurposeIn the literature, 65 years is commonly used as the age to designate an older person in the community. When studying older prisoners, there is much variation. The purpose of this paper is to investigate how researchers define older offenders and for what reasons.Design/methodology/approachThe authors reviewed articles on health and well-being of older offenders to assess terminology used to describe this age group, the chosen age cut-offs distinguishing younger offenders from older offenders, the arguments provided to support this choice as well as the empirical base cited in this context.FindingsThe findings show that the age cut-off of 50 years and the term "older" were most frequently used by researchers in the field. The authors find eight main arguments given to underscore the use of specific age cut-offs delineating older offenders. They outline the reasoning provided for each argument and evaluate it for its use to define older offenders.Originality/valueWith this review, it is hoped to stimulate the much-needed discussion advancing towards a uniform definition of the older offender. Such a uniform definition would make future research more comparable and ensure that there is no ambiguity when researchers state that the study population is "older offenders"
'The medical gaze and the watchful eye' : the treatment, prevention and epidemiology of venereal diseases in New South Wales c.1901 - 1925
From Federation in 1901 through the first three decades of the twentieth century there was a perceptible shift in modes of rule in New South Wales (NSW) related to the management of venereal diseases. At the beginning of the twentieth century a medicopenal approach was central. By 1925, persuasion and âresponsibilisationâ were becoming important modes, and young people rather than âcase-hardened prostitutes' were assessed as being a âvenerealâ risk. Framing this period were three important legislative developments which informed, and were informed by, these shifts: the NSW Prisoners Detention Act 1909, the NSW Select Committee into the Prevalence of Venereal Diseases 1915 and the NSW Venereal Diseases Act 1918. At its core this thesis is concerned with examining shifting modes of rule. This thesis closely examines each. I suggest that these modes of rule can be viewed through the lens of biopolitics, and following Foucault, deploy the âmedical gazeâ and the âwatchful eyeâ as constructs to examine the relationship between the government of self, government of others and government of the state. I use the medical gaze to describe not only the individual venereal patient attending a hospital and the body of the patient diagnosed with syphilis and/or gonorrhoea, but most importantly to describe the power relationship between the medical practitioner, the teaching hospital and the patient. I use the watchful eye in a more overarching way to suggest the suite of techniques and apparatus deployed by government to monitor and regulate the venereal body politic, both the populations perceived to be posing a venereal risk, and populations at risk of venereal infection. In relation to the venereal body and the venereal body politic, I analyse three fundamental aspects of the management of venereal diseases: treatment, prevention and epidemiology. Treatment: Over this period, treatment moved from lock institutions to outpatient clinics. Embodied in this change was a widespread institutional ambivalence towards treating venereal patients. I contend that treatment of venereal diseases was painful, prolonged and punitive precisely because of the moral sickness perceived to be at the iv heart of venereal infection. I track this ambivalence to a systemic fear of institutional âvenerealisationâ, which decreased perceptibly across the period. Closely analysing surviving patient records, I argue that in their conduct, venereal patients were often compliant, conscientious and responsible. Prevention: I argue that preventative approaches to venereal diseases became increasingly complex, and operated in three domains â preventative medicine (diagnosis, treatment and vaccination); public health prevention (notification, isolation and disinfection); and prevention education (social purity campaigns and sex hygiene). An emerging plethora of community-based organisations and campaigns began to shift the sites and practices of power. Epidemiology: I suggest that there was a shift from danger to risk in the conceptualisation of venereal diseases. This shift necessitated a focus on factors affecting populations, as opposed to factors affecting individuals. This in turn led to the deployment of various techniques to monitor the conduct of venereal populations. The NSW Venereal Diseases Act 1918 created two important new venereal categories: the ânotified personâ and the âdefaulter,â both of which came to permeate renditions of venereal patients throughout the 20th century
Local category-specific gamma band responses in the visual cortex do not reflect conscious perception
Which neural processes underlie our conscious experience? One theoretical view argues that the neural correlates of consciousness (NCC) reside in local activity in sensory cortices. Accordingly, local category-specific gamma band responses in visual cortex correlate with conscious perception. However, as most studies manipulated conscious perception by altering the amount of sensory evidence, it is possible that they reflect prerequisites or consequences of consciousness rather than the actual NCC. Here we directly address this issue by developing a new experimental paradigm in which conscious perception is modulated either by sensory evidence or by previous exposure of the images while recording intracranial EEG from the higher-order visual cortex of human epilepsy patients. A clear prediction is that neural processes directly reflecting conscious perception should be present regardless of how it comes about. In contrast, we observed that although subjective reports were modulated both by sensory evidence and by previous exposure, gamma band responses solely reflected sensory evidence. This result contradicts the proposal that local gamma band responses in the higher-order visual cortex reflect conscious perception
Factors Associated with Increased Analgesic Use in German Women with Endometriosis during the COVID-19 Pandemic
(1) Background: Endometriosis is a frequent chronic pain condition in women of fertile
age. Pain management with analgesics is frequently used by women with endometriosis. During the
COVID-19 pandemic, access to health services was temporarily restricted in various countries for
persons without serious conditions, resulting in increased physical and mental health issues. The
present study was conducted in order to assess the risk factors predicting increased analgesic intake
by women with endometriosis during the COVID-19 pandemic. (2) Methods: The increased intake
of over-the-counter (OTC) and prescription-only (PO) analgesics was assessed with an anonymous
online questionnaire, along with demographic, pandemic-specific, disease-specific, and mental health
characteristics. Anxiety and depression were assessed with the Generalized Anxiety Disorder Scale
(GAD-2) and the Patient Health Questionnaire for Depression (PHQ-2), respectively. Pain-induced
disability was assessed with the pain-induced disability index (PDI). (3) Results: A high educational
level (OR 2.719; 95% CI 1.137â6.501; p = 0.025) and being at higher risk for depressive disorders, as
measured by PHQ-2 â„ 3 (OR 2.398; 95% CI 1.055â5.450; p = 0.037), were independent risk factors
for an increased intake of OTC analgesics. Current global pain-induced disability (OR 1.030; 95% CI
1.007â1.054; p = 0.010) was identified as a risk factor for an increased intake of PO pain medication.
The degree of reduction in social support and in social networks were independent predictors of an
increased intake of PO analgesics in a univariate logistic regression analysis, but lost significance
when adjusted for additional possible influencing factors. (4) Conclusions: In this population, an
increased intake of OTC analgesics was related to a higher educational level and having a depressive
disorder, while a higher pain-induced disability was an independent risk factor for an increased
intake of PO analgesics. Pandemic-specific factors did not significantly and independently influence
an increased intake of analgesics in women with endometriosis during the first wave of the COVID19 pandemic in Germany. Healthcare providers should be aware of the possible factors related to
increased analgesic use in women with endometriosis in order to identify persons at risk for the
misuse of pain medication and to prevent potential adverse effects
Determinants of Pain-Induced Disability in German Women with Endometriosis during the COVID-19 Pandemic
(1) Background: The main aim of this research was to examine the factors leading to pain induced disability by assessing the impact of demographic, endometriosis-specific, pandemic-specific,
and mental health factors. (2) Methods: Women with endometriosis who attended online support
groups were invited to respond to an online survey during the first wave of the COVID-19 pandemic in
Germany. The Pain Disability Index (PDI) was employed to assess disability-related daily functioning.
Independent predictors of pain-induced disability were determined using univariate and multivariate
logistic regression analyses. (3) Results: The mean PDI score of the study population was 31.61
(SD = 15.82), which was significantly higher (p < 0.001) than that reported in a previously published
normative study of the German population. In the present study, a high level of pain-induced
disability, as defined by scores equal to or higher than the median of the study population, older age
(OR 1.063, 95% CI 1.010â1.120, p = 0.020), dysmenorrhea (OR 1.015, 95% CI 1.005â1.026, p = 0.005),
dysuria (OR 1.014; 95% CI 1.001â1.027, p = 0.029), lower back pain (OR 1.018, 95% CI 1.007â1.029,
p = 0.001), and impaired mental health (OR 1.271, 95% CI 1.134â1.425, p < 0.001) were found to be
independent risk factors. Pandemic-specific factors did not significantly influence the pain-induced
disability of the participants in this study. (4) Conclusions: The level of pain-induced disability was
significantly higher among the women with endometriosis than among women in the normative
German validation study. Our findings identified risk factors for experiencing a high level of pain induced disability, such as demographic and specific pain characteristics. Pandemic-specific factors
did not significantly and independently influence the pain-induced disability during the first wave
of the COVID-19 pandemic in Germany. Impaired mental health negatively influenced functioning
during daily activities. Thus, women with endometriosis should be managed by a multidisciplinary
team of healthcare professionals to prevent negative effects of pain-induced disability on their
quality of life
Lunar Outgassing, Transient Phenomena and The Return to The Moon, I: Existing Data
Herein the transient lunar phenomena (TLP) report database is subjected to a
discriminating statistical filter robust against sites of spurious reports, and
produces a restricted sample that may be largely reliable. This subset is
highly correlated geographically with the catalog of outgassing events seen by
the Apollo 15, 16 and Lunar Prospector alpha-particle spectrometers for
episodic Rn-222 gas release. Both this robust TLP sample and even the larger,
unfiltered sample are highly correlated with the boundary between mare and
highlands, as are both deep and shallow moonquakes, as well as Po-210, a
long-lived product of Rn-222 decay and a further tracer of outgassing. This
offers another significant correlation relating TLPs and outgassing, and may
tie some of this activity to sagging mare basalt plains (perhaps mascons).
Additionally, low-level but likely significant TLP activity is connected to
recent, major impact craters (while moonquakes are not), which may indicate the
effects of cracks caused by the impacts, or perhaps avalanches, allowing
release of gas. The majority of TLP (and Rn-222) activity, however, is confined
to one site that produced much of the basalt in the Procellarum Terrane, and it
seems plausible that this TLP activity may be tied to residual outgassing from
the formerly largest volcanic ffusion sites from the deep lunar interior. With
the coming in the next few years of robotic spacecraft followed by human
exploration, the study of TLPs and outgassing is both promising and imperiled.
We will have an unprecedented pportunity to study lunar outgassing, but will
also deal with a greater burden of anthropogenic lunar gas than ever produced.
There is a pressing need to study lunar atmosphere and its sources while still
pristine. [Abstract abridged.]Comment: 35 pages, 3 figures, submitted to Icarus. Other papers in series
found at http://www.astro.columbia.edu/~arlin/TLP
Safety and Efficacy of the Selective Progesterone Receptor Modulator Asoprisnil for Heavy Menstrual Bleeding With Uterine Fibroids: Pooled Analysis of Two 12-Month, Placebo-Controlled, Randomized Trials
Community annotation and bioinformatics workforce development in concertâLittle Skate Genome Annotation Workshops and Jamborees
Recent advances in high-throughput DNA sequencing technologies have equipped biologists with a powerful new set of tools for advancing research goals. The resulting flood of sequence data has made it critically important to train the next generation of scientists to handle the inherent bioinformatic challenges. The North East Bioinformatics Collaborative (NEBC) is undertaking the genome sequencing and annotation of the little skate (Leucoraja erinacea) to promote advancement of bioinformatics infrastructure in our region, with an emphasis on practical education to create a critical mass of informatically savvy life scientists. In support of the Little Skate Genome Project, the NEBC members have developed several annotation workshops and jamborees to provide training in genome sequencing, annotation and analysis. Acting as a nexus for both curation activities and dissemination of project data, a project web portal, SkateBase (http://skatebase.org) has been developed. As a case study to illustrate effective coupling of community annotation with workforce development, we report the results of the Mitochondrial Genome Annotation Jamborees organized to annotate the first completely assembled element of the Little Skate Genome Project, as a culminating experience for participants from our three prior annotation workshops. We are applying the physical/virtual infrastructure and lessons learned from these activities to enhance and streamline the genome annotation workflow, as we look toward our continuing efforts for larger-scale functional and structural community annotation of the L. erinacea genome
Globalization, multinationals and institutional diversity
This article aims to explore the impact of globalization and in particular multinationals on diversity within national varieties of capitalism. Do the actions of multinationals create more diversity within national systems, do they reduce diversity or do they have relatively little impact on diversity within national systems? The article argues that there are distinctive structures of institutional diversity across different national systems. Therefore, the question is not how do MNCs impact on institutional diversity per se but how do they impact on these different structures of diversity? In order to develop this argument, the paper also differentiates types of multinational. The article uses distinction between market-seeking, resource-seeking, efficiency-seeking and strategic asset-seeking in order to identify a range of different MNC activity across manufacturing, professional and financial sectors. These different sorts of MNC activity vary across time and contexts in terms of their significance. The article looks in detail at four different models of capitalism and examines how the entry of different sorts of multinationals with distinctive objectives impacts on the relationships between key social actors which underpin and reinforce these models. In this way, it suggests how institutional diversity within different types of capitalism may evolve under the impact of MNCs and globalization
Tectonic Controls on Gas Hydrate Distribution off SW Taiwan
The northern part of the South China Sea is characterized by widespread occurrence of bottom simulating reflectors (BSR) indicating the presence of marine gas hydrate. Because the area covers both a tectonically inactive passive margin and the termination of a subduction zone, the influence of tectonism on the dynamics of gas hydrate systems can be studied in this region. Geophysical data show that there are multiple thrust faults on the active margin while much fewer and smaller faults exist in the passive margin. This tectonic difference matches with a difference in the geophysical characteristics of the gas hydrate systems. High hydrate saturation derived from ocean bottom seismometer data and controlled source electromagnetic data and conspicuous highâamplitude reflections in PâCable 3D seismic data above the BSR are found in the anticlinal ridges of the active margin. In contrast all geophysical evidence for the passive margin points to normal to low hydrate saturations. Geochemical analyses of gas samples collected at seep sites on the active margin show methane with heavy ÎŽ13C isotope composition, while gas collected at the passive margin shows light carbon isotope composition. Thus, we interpret the passive margin as a typical gas hydrate province fuelled by biogenic production of methane and the active margin gas hydrate system as a system that is fuelled not only by biogenic gas production but also by additional advection of thermogenic methane from the subduction system
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