Transfer 2.0 and Beyond! An Update

Presentation given at the Charleston Conference on November 3, 2011. Information about Project Transfer (v. 2.0) for librarians and publishers

The Spectral and Statistical Properties of Turbulence Generated by a Vortex/Blade-Tip Interaction

The perpendicular interaction of a streamwise vortex with the tip of a lifting blade was studied in incompressible flow to provide information useful to the accurate prediction of helicopter rotor noise and the understanding of vortex dominated turbulent flows. The vortex passed 0.3 chord lengths to the suction side of the blade tip, providing a weak interaction. Single and two-point turbulence measurements were made using sub-miniature four sensor hot-wire probes 15 chord lengths downstream of the blade trailing edge; revealing the mean velocity and Reynolds stress tensor distributions of the turbulence, as well as its spanwise length scales as a function of frequency. The single point measurements show the flow downstream of the blade to be dominated by the interaction of the original tip vortex and the vortex shed by the blade. These vortices rotate about each other under their mutual induction, winding up the turbulent wakes of the blades. This interaction between the vortices appears to be the source of new turbulence in their cores and in the region between them. This turbulence appears to be responsible for some decay in the core of the original vortex, not seen when the blade is removed. The region between the vortices is not only a region of comparatively large stresses, but also one of intense turbulence production. Velocity autospectra measured near its center suggests the presence quasi-periodic large eddies with axes roughly parallel to a line joining the vortex cores. Detailed two-point measurements were made on a series of spanwise cuts through the flow so as to reveal the turbulence scales as they would be seen along the span of an intersecting airfoil. The measurements were made over a range of probe separations that enabled them to be analyzed not only in terms of coherence and phase spectra but also in terms of wave-number frequency (kappa-omega) spectra, computed by transforming the measured cross-spectra with respect to the spanwise separation of the probes. These data clearly show the influence of the coherent eddies in the spiral wake and the turbulent region between the cores. These eddies produce distinct peaks in the upwash velocity kappa-omega spectra, and strong anisotropy manifested both in the decay of the kappa-omega spectrum at larger wave-numbers and in differences between the kappa-omega spectra of different components. None of these features are represented in the von Karman spectrum for isotropic turbulence that is often used in broadband noise computations. Wave-number frequency spectra measured in the cores appear to show some evidence that the turbulence outside sets tip core waves, as has previously been hypothesized. These spectra also provide for the first time a truly objective method for distinguishing velocity fluctuations produced by core wandering from other motions

Bio-inspired canopies for the reduction of roughness noise

This work takes inspiration from the structure of the down covering the flight feathers of larger species of owls, which contributes to their ability to fly almost silently at frequencies above 1.6 kHz. Microscope photographs of the down show that it consists of hairs that form a structure similar to that of a forest. The hairs initially rise almost perpendicular to the feather surface but then bend over in the flow direction to form a canopy with an open area ratio of about 70 percent. Experiments have been performed to examine the noise radiated by a large open area ratio canopy suspended above a surface. The canopy is found to dramatically reduce pressure fluctuations on the underlying surface. While the canopy can produce its own sound, particularly at high frequencies, the reduction in surface pressure fluctuations can reduce the noise scattered from an underlying rough surface at lower frequencies. A theoretical model is developed which characterizes the mechanism of surface pressure reduction as a result of the mixing layer instability of flow over forest canopies.Office of Naval Research (Grant IDs: N00014-13-1-0244, N00014-14-1-0242

Numerical Investigation of Bio-Inspired Blade Designs at High Reynolds Numbers for Ultra-Quiet Aircraft and Wind Turbines

This paper presents numerical analysis of an airfoil geometry inspired by the down coat of the night owl. The objective is to understand the mechanisms of airfoil trailing edge noise reduction that has been observed with such designs in previous experiments. The NACA 0012 airfoil is selected as the baseline airfoil. The bioinspired geometry consists of an array of “finlets” that are applied near the trailing edge of the baseline airfoil and are aligned with the flow direction. Wall-resolved large eddy simulations (LES) are performed over the baseline and the bioinspired airfoil geometries and the aerodynamic and aeroacoustic performance of the two geometries are contrasted. Both models are simulated at chordbased Reynolds number Rec = 5 × 105 , flow Mach number, M∞ = 0.2, and angle of attack, α = 0◦ . The simulations are tripped in order to compare with experiments that are at much higher Rec (of the order of 2 M). Tripping is achieved using a geometry-resolved trip wire, placed at x/c = 0.05 from the airfoil leading edge. Comparisons with experimental data show good agreement for aerodynamic pressure coefficient (Cp) distribution for the baseline airfoil. Skin friction coefficient (Cf ) and Cp distributions are also found to compare well with XFOIL results obtained by similarly tripping the boundary layer. Surface pressure spectra comparisons between the baseline and the bioinspired airfoil near the airfoil trailing edge show reductions with the finlets of the order of 3 dB at high frequencies. Two hypotheses of noise reduction mechanisms are investigated: (1) reduction in spanwise correlation length, and (2) increase in source-’scattering edge’ separation distance. The simulations show insignificant difference in spanwise coherence between the two geometries, but clearly show that the finlets lift turbulence eddies away from the airfoil trailing edge hence reducing scattering efficiency

Three-dimensional instability during vortex merging

4 p.The interaction of two parallel vortices of equal circulation is observed experimentally. For low Reynolds numbers ($Re$), the vortices remain two-dimensional and merge into a single one, when their time-dependent core size exceeds approximately 30\% of the vortex separation distance. At higher $Re$, a three-dimensional instability is discovered, showing the characteristics of an elliptic instability of the vortex cores. The instability rapidly generates small-scale turbulent motion, which initiates merging for smaller core sizes and produces a bigger final vortex than for laminar 2D flow

Bioinspired trailing-edge noise control

Strategies for trailing edge noise control have been inspired by the downy canopy that covers the surface of exposed flight feathers of many owl species. Previous wind tunnel measurements demonstrate that canopies of similar characteristics can reduce pressure fluctuations on the underlying surface by as much as 30dB, and significantly attenuate roughness noise generated by that surface. In the present work, surface treatments are designed to replicate the effects of the canopy in a form suitable for application to an airfoil. These treatments are installed directly upstream of the trailing edge to modify the boundary layer turbulence prior to acoustic scattering by the edge. Over 20 variants of these designs have been tested by performing aeroacoustic wind tunnel measurements on a tripped DU96-W180 airfoil at chord Reynolds numbers of up to 3 million. Compared to the unmodified airfoil, the treatments provided up to 10dB of broadband attenuation of trailing edge noise. The effectiveness of the treatment is not highly dependent on a particular geometry, but there appears to be strong potential for optimization. The surface treatments remain effective over an angle of attack range that extends over 9 degrees from zero lift. Aerodynamic impact of the treatment appears minimal.Office of Naval Research (Grant IDs: N00014-13-1-0244, N00014-14-1-0242, N62909-12-1-7116 (NICOP)), College of Engineering at Virginia Tech, AVEC Incorporate

The rheumatoid arthritis treat-to-target trial: a cluster randomized trial within the Corrona rheumatology network

BACKGROUND: The treat-to-target (T2T) approach to the care of patients with rheumatoid arthritis involves using validated metrics to measure disease activity, frequent follow-up visits for patients with moderate to high disease activity, and escalation of therapy when patients have inadequate therapeutic response as assessed by standard disease activity scores. The study described is a newly launched cluster-randomized behavioral intervention to assess the feasibility and effectiveness of the T2T approach in US rheumatology practices. It is designed to identify patient and provider barriers to implementing T2T management. This initial paper focuses on the novel study design and methods created to provide these insights. METHODS/DESIGN: This trial cluster-randomizes rheumatology practices from the existing Corrona network of private and academic sites rather than patients within sites or individual investigators to provide either T2T or usual care (UC) for qualified patients who meet the 2010 revised American College of Rheumatology criteria for the diagnosis of rheumatoid arthritis and have moderate to high disease activity. Specific medication choices are left to the investigator and patient, rather than being specified in the protocol. Enrollment is expected to be completed by the end of 2013, with 30 practices randomized and enrolling a minimum of 530 patients. During the 12-month follow-up, visits are mandated as frequently as monthly in patients with active disease in the T2T group and every 3 months for the UC group. Safety data are collected at each visit. The coprimary endpoints include a comparison of the proportion of patients achieving low disease activity in the T2T and UC groups and assessment of the feasibility of implementing T2T in rheumatology practices, specifically assessment of the rates of treatment acceleration, frequency of visits, time to next visit conditional on disease activity, and probability of acceleration conditional on disease activity in the 2 groups. DISCUSSION: This cluster-randomized behavioral intervention study will provide valuable insights on the outcomes and feasibility of employing a T2T treatment approach in clinical practice in the United States. TRIAL REGISTRATION: NCT01407419

PS Integrins and Laminins: Key Regulators of Cell Migration during Drosophila Embryogenesis

During embryonic development, there are numerous cases where organ or tissue formation depends upon the migration of primordial cells. In the Drosophila embryo, the visceral mesoderm (vm) acts as a substrate for the migration of several cell populations of epithelial origin, including the endoderm, the trachea and the salivary glands. These migratory processes require both integrins and laminins. The current model is that αPS1βPS (PS1) and/or αPS3βPS (PS3) integrins are required in migrating cells, whereas αPS2βPS (PS2) integrin is required in the vm, where it performs an as yet unidentified function. Here, we show that PS1 integrins are also required for the migration over the vm of cells of mesodermal origin, the caudal visceral mesoderm (CVM). These results support a model in which PS1 might have evolved to acquire the migratory function of integrins, irrespective of the origin of the tissue. This integrin function is highly specific and its specificity resides mainly in the extracellular domain. In addition, we have identified the Laminin α1,2 trimer, as the key extracellular matrix (ECM) component regulating CVM migration. Furthermore, we show that, as it is the case in vertebrates, integrins, and specifically PS2, contributes to CVM movement by participating in the correct assembly of the ECM that serves as tracks for migration