Parental perceptions of their child\u27s weight and health

Childhood obesity is a major health problem facing children in the United States. How parents view their children\u27s weight is an important consideration for health care professionals. The purpose of this study was to explore parental perceptions of their children\u27s weight and health

The Role Of Working Memory And Linguistic Knowledge On Language Performance

The language system is highly flexible and draws on distinct but interconnected cognitive mechanisms, including verbal working memory and long-term linguistic knowledge. Verbal working memory is the ability to manipulate verbal information in mind. Long-term linguistic knowledge refers to our knowledge of the language (i.e., phonology, semantics, syntax), stored in long-term memory. The close interaction between verbal working memory and linguistic knowledge highlights a pressing need to investigate the construct of verbal working memory, its separability and its relationship with linguistic knowledge. To understand the way working memory influences and interacts with language abilities in children and adults, I ask the following questions: Are verbal working memory and language separable constructs? And, does verbal working memory operate within a dynamic network of cognitive systems including the language network? In Chapter 2, I examined whether working memory and linguistic abilities could be teased apart using the same language task, namely a modified Token Test. Indeed, factors related to working memory and linguistic abilities explained performance on our modified Token Test and were differentially related to other language measures. Despite evidence of separability, it must be acknowledged that verbal working memory and language processing are highly intertwined. Chapters 3 and 4 investigated this interrelationship in detail. Specifically, I used experimental tasks to delineate the involvement of phonological and semantic representations in the maintenance of verbal items (words, sentences) in working memory. In Chapter 3, I used a novel word recognition paradigm and found separable phonological and semantic effects on immediate memory, with semantic processing supporting long-term retention. These findings confirmed that both phonological and semantic information were readily activated and accessed when a word is encountered and processed. Chapter 4 further evaluated the interplay between different cognitive processes underlying verbal working memory in the context of sentence recall. Similarly, results supported the idea that multiple representations influence performance, but their contributions differ. Semantic processing was beneficial for both immediate and long-term memory whereas phonological processing had more immediate benefits. Finally, in the concluding chapter, I discuss the importance of these results for models of verbal short-term memory and highlight some potential implications for clinical practice

A multi-microcontroller-based hardware for deploying Tiny machine learning model

The tiny machine learning (TinyML) has been considered to applied on the edge devices where the resource-constrained micro-controller units (MCUs) were used. Finding a good platform to deploy the TinyML effectively is very crucial. The paper aims to propose a multiple micro-controller hardware platform for productively running the TinyML model. The proposed hardware consists of two dual-core MCUs. The first MCU is utilized for acquiring and processing input data, while the second is responsible for executing the trained TinyML network. Two MCUs communicate to each other using the universal asynchronous receiver-transmitter (UART) protocol. The multi-tasking programming technique is mainly applied on the first MCU to optimize the pre-processing new data. A three-phase motors faults classification TinyML model was deployed on the proposed system to evaluate the effectiveness. The experimental results prove that our proposed hardware platform was improved 34.8% the total inference time including pre-processing data of the proposed TinyML model in comparing with single micro-controller hardware platform

LEARNING IDIOMS FOR ENGLISH MAJORS: VIETNAMESE STUDENTS’ PERCEPTIONS OF DIFFICULTIES AND LEARNING STRATEGIES

Learning idioms play an influential role in language generally and in English notably. Comprehending idioms assists language learners in integrating culture, enhancing skills, and ameliorating English levels. Numerous studies have analyzed the function of idioms in second language acquisition (Cieślicka, 2015). This study investigates the difficulties and strategies used in learning idioms by English-majored students at a regional public university (PU) in the south of Vietnam. This paper furnishes data showing learners’ perceptions of facing complications and learning methods. The samples consisted of 150 undergraduate EFL students from English-medium instruction programs. The data was analyzed by utilizing descriptive and inferential statistics. The findings reveal that students struggle to understand idiomatic terms without specific, understandable contexts. Furthermore, the results indicate that the most frequently employed strategies are guessing the meaning of idioms, learning idioms through keywords, and learning from a range of sources, particularly via media. The findings also mentioned that low-proficiency and high-proficiency students encounter identical challenges, with no significant differences. The study's results revealed that the majority of students have difficulty acquiring, recognizing, and interpreting idioms. The findings indicated that guessing the implication of idioms is the most used strategy.  Article visualizations

Comparison between Nanoparticle Encapsulation and Surface Loading for Lysosomal Enzyme Replacement Therapy

Poly(lactide-co-glycolide) (PLGA) nanoparticles (NPs) enhance the delivery of therapeutic enzymes for replacement therapy of lysosomal storage disorders. Previous studies examined NPs encapsulating or coated with enzymes, but these formulations have never been compared. We examined this using hyaluronidase (HAse), deficient in mucopolysaccharidosis IX, and acid sphingomyelinase (ASM), deficient in types A–B Niemann–Pick disease. Initial screening of size, PDI, ζ potential, and loading resulted in the selection of the Lactel II co-polymer vs. Lactel I or Resomer, and Pluronic F68 surfactant vs. PVA or DMAB. Enzyme input and addition of carrier protein were evaluated, rendering NPs having, e.g., 181 nm diameter, 0.15 PDI, −36 mV ζ potential, and 538 HAse molecules encapsulated per NP. Similar NPs were coated with enzyme, which reduced loading (e.g., 292 HAse molecules/NP). NPs were coated with targeting antibodies (> 122 molecules/NP), lyophilized for storage without alterations, and acceptably stable at physiological conditions. NPs were internalized, trafficked to lysosomes, released active enzyme at lysosomal conditions, and targeted both peripheral organs and the brain after i.v. administration in mice. While both formulations enhanced enzyme delivery compared to free enzyme, encapsulating NPs surpassed coated counterparts (18.4- vs. 4.3-fold enhancement in cells and 6.2- vs. 3-fold enhancement in brains), providing guidance for future applications

DIFFICULTIES WITH WORD CHOICE IN ACADEMIC WRITING AND SOLUTIONS: A RESEARCH ON ENGLISH-MAJORED STUDENTS AT CAN THO UNIVERSITY, VIETNAM

Writing, especially academic writing, is highly valued in foreign language acquisition, particularly for English majors. Nevertheless, using academic terminology might be difficult for students still developing their academic language abilities. The purpose of this research is to understand students' difficulties in selecting appropriate words in academic writing and offer solutions to overcome such difficulties. The participants were 78 English majors (high-quality program, course 45) and three lecturers at the Department of English Language and Culture, School of Foreign Languages, Can Tho University. Questionnaires were used to measure their difficulties in word choice in academic writing and semi-structured interviews were utilized to find solutions. The results show that most participants had a basic knowledge of academic vocabulary, which was demonstrated through their ability to select the appropriate word choice. However, students found it difficult to choose the right words in their academic writing. The reasons are that academic words are not easy to remember and not successfully used in the context of the meaning of the word and do not have an effective method of learning academic vocabulary. Based on the results, several specific approaches have been proposed to help students find the most suitable strategies for learning and using academic vocabulary for their writing.  Article visualizations

Antidepressant augmentation versus switch in treatment-resistant geriatric depression

BACKGROUND: The benefits and risks of augmenting or switching antidepressants in older adults with treatment-resistant depression have not been extensively studied. METHODS: We conducted a two-step, open-label trial involving adults 60 years of age or older with treatment-resistant depression. In step 1, patients were randomly assigned in a 1:1:1 ratio to augmentation of existing antidepressant medication with aripiprazole, augmentation with bupropion, or a switch from existing antidepressant medication to bupropion. Patients who did not benefit from or were ineligible for step 1 were randomly assigned in step 2 in a 1:1 ratio to augmentation with lithium or a switch to nortriptyline. Each step lasted approximately 10 weeks. The primary outcome was the change from baseline in psychological well-being, assessed with the National Institutes of Health Toolbox Positive Affect and General Life Satisfaction subscales (population mean, 50; higher scores indicate greater well-being). A secondary outcome was remission of depression. RESULTS: In step 1, a total of 619 patients were enrolled; 211 were assigned to aripiprazole augmentation, 206 to bupropion augmentation, and 202 to a switch to bupropion. Well-being scores improved by 4.83 points, 4.33 points, and 2.04 points, respectively. The difference between the aripiprazole-augmentation group and the switch-to-bupropion group was 2.79 points (95% CI, 0.56 to 5.02; P = 0.014, with a prespecified threshold P value of 0.017); the between-group differences were not significant for aripiprazole augmentation versus bupropion augmentation or for bupropion augmentation versus a switch to bupropion. Remission occurred in 28.9% of patients in the aripiprazole-augmentation group, 28.2% in the bupropion-augmentation group, and 19.3% in the switch-to-bupropion group. The rate of falls was highest with bupropion augmentation. In step 2, a total of 248 patients were enrolled; 127 were assigned to lithium augmentation and 121 to a switch to nortriptyline. Well-being scores improved by 3.17 points and 2.18 points, respectively (difference, 0.99; 95% CI, -1.92 to 3.91). Remission occurred in 18.9% of patients in the lithium-augmentation group and 21.5% in the switch-to-nortriptyline group; rates of falling were similar in the two groups. CONCLUSIONS: In older adults with treatment-resistant depression, augmentation of existing antidepressants with aripiprazole improved well-being significantly more over 10 weeks than a switch to bupropion and was associated with a numerically higher incidence of remission. Among patients in whom augmentation or a switch to bupropion failed, changes in well-being and the occurrence of remission with lithium augmentation or a switch to nortriptyline were similar. (Funded by the Patient-Centered Outcomes Research Institute; OPTIMUM ClinicalTrials.gov number, NCT02960763.)