Properties of ρ\rho and ω\omega Mesons at Finite Temperature and Density as Inferred from Experiment

The mass shift, width broadening, and spectral density for the $\rho$ and $\omega$ mesons in a heat bath of nucleons and pions are calculated using a general formula which relates the self-energy to the real and imaginary parts of the forward scattering amplitude. We use experimental data to saturate the scattering amplitude at low energies with resonances and include a background Pomeron term, while at high energies a Regge parameterization is used. The real part obtained directly is compared with the result of a dispersion integral over the imaginary part. The peaks of the spectral densities are little shifted from their vacuum positions, but the widths are considerably increased due to collisional broadening. Where possible we compare with the UrQMD model and find quite good agreement. At normal nuclear matter density and a temperature of 150 MeV the spectral density of the $\rho$ meson has a width of 345 MeV, while that for the $\omega$ is in the range 90--150 MeV.Comment: 21 pages revtex + 9 postscript figure

Spectrum and Variability of Mrk501 as observed by the CAT Imaging Telescope

The CAT Imaging Telescope has observed the BL Lac object Markarian 501 between March and August 1997. We report here on the variability over this time including several large flares. We present also preliminary spectra for all these data, for the low emission state, and for the largest flare.Comment: 4 pages, 4 figures, Late

Observation of the Crab Nebula Gamma-Ray Emission Above 220 Gev by the Cat Cherenkov Imaging Telescope

The CAT imaging telescope, recently built on the site of the former solar plant Themis (French Pyrenees), observed gamma-rays from the Crab nebula from October 1996 to March 1997. This steady source, often considered as the standard candle of very-high-energy gamma-ray astronomy, is used as a test-beam to probe the performances of the new telescope, particularly its energy threshold (220 GeV at 20 degrees zenith angle) and the stability of its response. Due to the fine-grain camera, an accurate analysis of the longitudinal profiles of shower images is performed, yielding the source position in two dimensions for each individual shower.Comment: 5 pages, 3 figures, Tex, contribution to 25th ICRC Durba

Detection of Vhe Gamma-Rays from MRK 501 with the Cat Imaging Telescope

The CAT imaging telescope on the site on the former solar plant Themis has been observing gamma-rays from Mrk501 above 220 GeV in March and April 1997. This source is shown to be highly variable and the light curve is presented. The detected gamma-ray rate for the most intense flare is in excess of 10 per minute.Comment: 5 pages, 4 figures, Tex, contribution to 25th ICRC Durba

Delta rho pi interaction leading to N* and Delta* resonances

We have performed a calculation for the three body $\Delta \rho \pi$ system by using the fixed center approximation to Faddeev equations, taking the interaction between $\Delta$ and $\rho$, $\Delta$ and$\pi$, and $\rho$ and $\pi$ from the chiral unitary approach. We find several peaks in the modulus squared of the three-body scattering amplitude, indicating the existence of resonances, which can be associated to known $I=1/2, 3/2$ and $J^P=1/2^+, 3/2^+$ and $5/2^+$ baryon states.Comment: Presented at the 21st European Conference on Few-Body Problems in Physics, Salamanca, Spain, 30 August - 3 September 201

Model dependence of single-energy fits to pion photoproduction data

Model dependence of multipole analysis has been explored through energy-dependent and single-energy fits to pion photoproduction data. The MAID energy-dependent solution has been used as input for an event generator producing realistic pseudo data. These were fitted using the SAID parametrization approach to determine single-energy and energy-dependent solutions over a range of lab photon energies from 200 to 1200 MeV. The resulting solutions were found to be consistent with the input amplitudes from MAID. Fits with a $\chi$-squared per datum of unity or less were generally achieved. We discuss energy regions where consistent results are expected, and explore the sensitivity of fits to the number of included single- and double-polarization observables. The influence of Watson's theorem is examined in detail.Comment: 12 pages, 8 figure

Genetic risk for schizophrenia and psychosis in Alzheimer disease

Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent in Alzheimer disease (AD), affecting ~40 to 60% of individuals with AD (AD with psychosis (AD+P)). In comparison with AD subjects without psychosis, AD+P subjects have more rapid cognitive decline and poor outcomes. Prior studies have estimated the heritability of psychosis in AD at 61%, but the underlying genetic sources of this risk are not known. We evaluated a Discovery Cohort of 2876 AD subjects with (N=1761) or without psychosis (N=1115). All subjects were genotyped using a custom genotyping array designed to evaluate single-nucleotide polymorphisms (SNPs) with evidence of genetic association with AD+P and include SNPs affecting or putatively affecting risk for schizophrenia and AD. Results were replicated in an independent cohort of 2194 AD subjects with (N=734) or without psychosis (N=1460). We found that AD+P is associated with polygenic risk for a set of novel loci and inversely associated with polygenic risk for schizophrenia. Among the biologic pathways identified by the associations of schizophrenia SNPs with AD+P are endosomal trafficking, autophagy and calcium channel signaling. To the best of our knowledge, these findings provide the first clear demonstration that AD+P is associated with common genetic variation. In addition, they provide an unbiased link between polygenic risk for schizophrenia and a lower risk of psychosis in AD. This provides an opportunity to leverage progress made in identifying the biologic effects of schizophrenia alleles to identify novel mechanisms protecting against more rapid cognitive decline and psychosis risk in AD