757 research outputs found

    Eurasianist Trends in Russian Foreign Policy: A Critical Analysis

    Get PDF
    This paper examines and illustrates the presence of a powerful Eurasianist doctrine currently informing Russian foreign policy. It first presents the historical evolution of Eurasianism, its most recent incarnation present in contemporary Russia, and later seeks to explicate its development. The emergence of this particular doctrine was the result of a gradual process that began in 2000 when Vladimir Putin first became President of the Russian Federation although its historical roots are traced back to the 19th century. Over the course of the past decade a new brand of Eurasianism has emerged which this study identifies as \u27Geopolitical Eurasianism\u27. Various external and internal factors have led to the rise of this paradigm which now dominates the formulation and implementation of Russian foreign policy. Ultimately Geopolitical Eurasianism is shown to be the principle doctrine guiding Russian foreign policy over the past decade and demonstrates that Russia will most likely continue on this current trajectory

    Perceptions of Occupational erapy Students and Faculty of Compressed Courses: A Pilot Study

    Get PDF
    As occupational therapists, our mandate is to be client centered, yet in academic settings there is little information regarding student or faculty preferences about curriculum and course design. This study investigated the perceptions of occupational therapy students and faculty regarding the delivery of content in a compressed course format, thus reducing the number of courses taken at any given time. The authors discuss how the results inform the feasibility of incorporating this format into future curriculum design. A descriptive survey design was used for this study. The participants were 33 entry-level graduate students and two faculty who completed post-course surveys for two courses. The results show that overall perceptions of students and faculty were positive regarding the compressed course format. The students had fewer courses to focus on and faculty had increased time to devote to other responsibilities. This study provides preliminary evidence for the feasibility of alternative curriculum design in the future and lays the foundation for further research in occupational therapy curriculum design. It directly responds to the needs identified by the American Occupational Therapy Association in the occupational therapy education research agenda

    The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fission

    Get PDF
    Yeast mitochondrial fission is a multistep process during which the dynamin-related GTPase, Dnm1p, assembles into punctate structures that associate with the outer mitochondrial membrane and mediate mitochondrial division. Steps in the Dnm1p-dependent process of fission are regulated by the actions of the WD repeat protein, Mdv1p, and the mitochondrial outer membrane protein, Fis1p. Our previous studies suggested a model where Mdv1p functions to regulate fission at a post-Dnm1p assembly step and Fis1p functions at two distinct steps, at an early point, to regulate Dnm1p assembly, and later, together with Mdv1p, to facilitate Dnm1p-dependent mitochondrial fission. To test this model, we have examined the physical and functional relationship between Mdv1p and Fis1p and present genetic, biochemical, and two-hybrid data indicating that a Fis1p–Mdv1p complex is required to regulate mitochondrial fission. To further define the role of Mdv1p in fission, we examined the structural features of Mdv1p required for its interactions with Dnm1p and Fis1p. Data from two-hybrid analyses and GFP-tagged domains of Mdv1p indicate that it contains two functionally distinct domains that enable it to function as a molecular adaptor to regulate sequential interactions between Dnm1p and Fis1p and catalyze a rate-limiting step in mitochondrial fission

    Hybrid analytical and numerical approach for modeling fluid flow in simplified three-dimensional fracture networks

    Get PDF
    <jats:p>Modeling fluid flow in three-dimensional fracture networks is required in a wide variety of applications related to fractured rocks. Numerical approaches developed for this purpose rely on either simplified representations of the physics of the considered problem using mesh-free methods at the fracture scale or complex meshing of the studied systems resulting in considerable computational costs. Here, we derive an alternative approach that does not rely on a full meshing of the fracture network yet maintains an accurate representation of the modeled physical processes. This is done by considering simplified fracture networks in which the fractures are represented as rectangles that are divided into rectangular subfractures such that the fracture intersections are defined on the borders of these subfractures. Two-dimensional analytical solutions for the Darcy-scale flow problem are utilized at the subfracture scale and coupled at the fracture-network scale through discretization nodes located on the subfracture borders. We investigate the impact of parameters related to the location and number of the discretization nodes on the results obtained, and we compare our results with those calculated using reference solutions, which are an analytical solution for simple configurations and a standard finite-element modeling approach for complex configurations. This work represents a first step towards the development of 3D hybrid analytical and numerical approaches where the impact of the surrounding matrix will be eventually considered.</jats:p&gt
    corecore