Supplier-contractor collaboration in the construction industry:A taxonomic approach to the literature of the 2000-2009 decade

Purpose – Recent developments in the construction industry resulted in an increased importance of collaboration with and managing of suppliers by prime contractors. The focus of this study is on getting insights into existing knowledge on this topic and the gaps in this knowledge base. The goals of this study are threefold: to verify the current state of, to gain insights into, and to provide suggestions for supplier-contractor research. Design/methodology/approach – The current state of supplier-contractor research in the construction industry is verified through a taxonomic approach to the literature on buyer-supplier research over the last decade (2000-2009). The method followed consists of the following three steps: journal selection, initial article selection and final article selection. Findings – Supplier-contractor research in the construction industry is still a relatively under-researched phenomenon. The major topics discussed in the identified articles are aspects of partnering (conditions, characteristics and barriers/obstacles) and (sub)contracting/procurement issues (practices, selection criteria, performance and characteristics). Research limitations/implications – This study concludes that future research should focus on longitudinal studies, testing organisational barriers to partnering, the benefits of partnering in practice, conditions under which the formation of collaborative relationships between suppliers and contractors takes place, and experiences with this formation process. Practical implications – In practice, contractors do see a need to develop closer and more collaborative relationships with their suppliers. This study highlights the topics that need to be addressed to achieve these goals. Originality/value – This study is a literature overview of relatively scarce research on collaborative relationships between suppliers and contractors in the construction industry

Function of the Endolysosomal Network in Cholesterol Homeostasis and Metabolic Associated Fatty Liver Disease (MAFLD)

BACKGROUND: Metabolic associated fatty liver disease (MAFLD), also known as non-alcoholic fatty liver disease, has become the leading cause of chronic liver disease worldwide. Besides hepatic accumulation of triglycerides, dysregulated cholesterol metabolism is an important contributor to the pathogenesis of MAFLD. Maintenance of cholesterol homeostasis is highly dependent on cellular cholesterol uptake, and subsequently cholesterol transport to other membrane compartments, such as the endocytic reticulum (ER). SCOPE OF REVIEW: The endolysosomal network is key for regulating cellular homeostasis and adaptation, and emerging evidence has shown that the endolysosomal network is crucial to maintain metabolic homeostasis. In this review, we will summarize our current understanding of the role of the endolysosomal network in cholesterol homeostasis and its implications in MAFLD pathogenesis. MAJOR CONCLUSIONS: Although multiple endolysosomal proteins have been identified in the regulation of cholesterol uptake, intracellular transport, and degradation, their physiological role is incompletely understood. Further research should elucidate their role in controlling metabolic homeostasis and development of fatty liver disease

Normal stresses in semiflexible polymer hydrogels

Biopolymer gels such as fibrin and collagen networks are known to develop tensile axial stress when subject to torsion. This negative normal stress is opposite to the classical Poynting effect observed for most elastic solids including synthetic polymer gels, where torsion provokes a positive normal stress. As recently shown, this anomalous behavior in fibrin gels depends on the open, porous network structure of biopolymer gels, which facilitates interstitial fluid flow during shear and can be described by a phenomenological two-fluid model with viscous coupling between network and solvent. Here we extend this model and develop a microscopic model for the individual diagonal components of the stress tensor that determine the axial response of semi-flexible polymer hydrogels. This microscopic model predicts that the magnitude of these stress components depends inversely on the characteristic strain for the onset of nonlinear shear stress, which we confirm experimentally by shear rheometry on fibrin gels. Moreover, our model predicts a transient behavior of the normal stress, which is in excellent agreement with the full time-dependent normal stress we measure.Comment: 12 pages, 8 figure

Assessment of the pollution status of alluvial plains : a case study for the dredged sediment-derived soils along the Leie River

The concept of an integrated multifunctional river management is gaining importance. For major rivers, restoring the contact between rivers and alluvial plains is an important goal, as riparian areas have a specific role for several riverine processes. However, former and current human activities are an obstruction or a limitation for river restoration. We studied the influence of former dredging activities along the river Leie on the alluvial plain quality. A soil survey and an archive query for reconstructing the history of dredging operations were conducted simultaneously. The geographical impact expressed as topographical changes and covering of the original soil profile and related processes and biota was large. The pollution status of dredged sediment-derived soils was found to be far from negligible: concentrations of Cd, Cr, and Zn were, in 10% of the cases, higher than 20, 480, and 2800 mg kg(-1) DM, respectively. Both agriculture and nature rehabilitation on dredged sediment-derived soils can only be accepted after profound risk assessment, and management should focus on ecological risk reduction. Results indicate the importance of soil quality assessment in alluvial plains for an integrated river management, rather than a priori assuming pristine soil conditions. The collected "off-line" sediment data can be used as a reconstruction of past sediment pollution, especially when long-term sediment monitoring programs are not available

Kleine deeltjes, grote kwesties: Een issueanalyse van de maatschappelijke dialoog nanotechnologie

Dit artikel beantwoordt de vraag welke kwesties aan bod zijn gekomen in de Maatschappelijke Dialoog Nanotechnologie en in hoeverre deze dialoog heeft bijgedragen aan verbreding van het debat. Is het gelukt naast een technologisch ook een maatschappelijk perspectief neer te zetten? Naast de issueanalyse is ook onderzocht welke organisaties hierbij betrokken zijn geweest en de mogelijkheden die zij boden voor publieksinbren

Distinguished Brief

The Government of the Republic of Bretoria and the Kingdom of Pagonia have agreed to submit by Special Agreement the present controversy for final solution to the International Court of Justice pursuant to Article 36, paragraph 1 of the Statute of the International Court of Justice, in relation to Article 40, paragraph 1, of the Statute of the Court