321 research outputs found

    Hervorming van die Suid-Afrikaanse huweliksgoederereg* II

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    “Seen in the global context, the South African Law of husband and wife has, for better or worse, fallen behind developments overseas. Legal equality of husband and wife is by now firmly enshrined in the laws of Germany, France, the Netherlands, the United States of America and other Western countries”1)

    Comparison of forward and reverse single-file reciprocation for root canal instrumentation in curved mandibular molar canals - a Micro-CT analysis

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    To compare (i) canal centering ability and transportation of Primary WaveOne Gold in combination with WaveOne Gold Glider with ProTaper Next X2 in combination with ProGlider using Micro-CT, and (ii) difference in final preparation times between these two preparation groups. Mesiobuccal canals of 50 mandibular first molars were used. Teeth were randomly divided into two preparation groups. Results were analysed using a one-way analysis of variance (ANOVA). Apically, ProGlider/ProTaper Next X2 demonstrated better centering ratio values and lower transportation values compared to WaveOne Gold Glider/Primary WaveOne Gold (p<.05). No differences were found in the mean combined centering ratios and transportation values between groups (p>.05). No statistically significant differences between the canal preparation times were found (p<.06). The combination of ProGlider /ProTaper Next X2 yields better results for transportation and centering ability apically compared to WaveOne Gold Glider in combination with Primary Wave-One Gold

    Factors influencing apical debris extrusion during endodontic treatment - A review of the literature

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    The primary cause of a periapical inflammatory lesion is intra-radicular microbial infection. Prevention and elimination of apical periodontitis is achieved through successful endodontic treatment. Endodontic treatment is designed to maintain and restore the health of the periapical tissues and prevent periapical disease. It may be defined as the combination of mechanical instrumentation of the root canal system with bactericidal irrigation and obturation with an inert material. Technically, the goal of instrumentation and irrigation is to debride and entirely remove infected tissue debris from the root canal system and create a uniform conical shape that allows medicament delivery and adequate obturation. Microbiologically, the goal of instrumentation and irrigation is to eliminate micro-organisms, reduce their survival in the root canal system and neutralise any antigenic potential of the microbial components remaining in the canal

    Evaluation of preparation times of WaveOne Gold reciprocating instruments compared to two analogous counterparts

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    Manufacturers are constantly developing new products to optimise endodontic treatment. These newer file systems are often associated with increasing expenditure of instrumentation and can affect the cost effectiveness of root canal treatment. Recently, companies have emerged that claim to have successfully reproduced many of the more established endodontic file systems manufactured by Dentsply Sirona (Ballaigues, Switzerland). EdgeEndo (Albuquerque, New Mexico, USA) and PacDent (Brea, CA, USA), which manufacture files similar in design to that of Dentsply Sirona, claim that they are similar and sell them at a lower price. A performance comparison of the replica file systems to their original is of clinical importance. The aim of this ex vivo study was to compare the total glide path and canal preparation times of WaveOne Gold Glider (Dentsply Sirona) combined with the Primary WaveOne Gold (Dentsply Sirona), Edge GlidePath (Edge Endo, Albuquerque, New Mexico, USA) followed by the Primary EdgeOne Fire (EdgeEndo); and One File G Glide Path (Pac-Dent, Brea, CA, USA) file combined with the Primary One File G (Pac-Dent) Shaping file. Sixty curved untreated canals of extracted, human, mandibular molars were randomly divided into three groups of 20 canals each for mechanical glide path enlargement and root canal shaping. Group 1 (WaveOne Gold Glider + Primary WaveOne Gold); Group 2 (Edge GlidePath + Primary EdgeOne Fire); and Group 3 (One File G Reciprocating Glide Path File + Primary One File G Reciprocating shaping file). The total time taken to prepare a glide path and to complete the root canal preparation of each canal was recorded (in seconds) by means of an iPhone stopwatch (Apple Inc., Cupertino, California). The time taken to change files was not recorded. Throughout the instrumentation process, RC Prep was used as a lubricant, and5 mL 3% sodium hypochlorite was used as irrigation solution. Mean and standard deviations were determined for each group, and analysis of variance was used to statistically compare the mean glide path preparation times for the three groups. The fastest final canal preparation time was achieved by WOGG/PWOG (41.78 ± 10.58 s), followed by OFGP/ POFS (42.02 ± 12.16 s) and then EGP/PEOF (42.49 ± 10.44 s). There were no statistically significant differences between the canal preparation times of the three combination groups (p>0.05)

    Shaping ability of WaveOne Gold reciprocating instruments compared to two analogous counterparts

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    The aim of this study was to evaluate and compare canalcentering ability and transportation of three analogous reciprocating shaping instruments after glide path preparation. Radiographs were used to select sixty untreated mesiobuccal canals with curvatures of 25° to 35° from extracted, human, mandibular molars. The canals were randomly divided into three groups for glide path preparation and shaping (n = 20): Group TWOG (WaveOne Gold Glider + Primary WaveOne Gold); Group TEF (Edge GlidePath + Primary EdgeOne Fire); and Group TOFG (One File G Reciprocating Glide Path File + Primary Shaping file). Pre- and post-preparation micro-CT scans were compared at levels 7 mm (coronal), 5 mm (midroot), and 3 mm (apical) from the apex to evaluate transportation and centering ratios. There were no significant differences in centering ratios at the coronal and midroot levels (P > 0.05). Transportation values were similar at the coronal level and for the combined  mean values (P > 0.05). Transportation values for TEF and TWOG were similar (P = 0.98) at the midroot level but significantly lower than TOFG (P = 0.04). Apically, TEF remained significantly more centered with significantly lower transportation values than TWOG and TOFG (P < 0.05). Combined results showed that TEF was significantly more centered than TWOG but similar to TOFG (P = 0.017). Centering ratios and transportation values were more favorable in the apical region after use of TEF. All three groups evaluated in this study proved to be safe for the preparation of moderately curved root canals

    Spatially resolved XMM-Newton analysis and a model of the nonthermal emission of MSH 15-52

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    We present an X-ray analysis and a model of the nonthermal emission of the pulsar wind nebula (PWN) MSH15-52. We analyzed XMM-Newton data to obtain the spatially resolved spectral parameters around the pulsar PSRB1509-58. A steepening of the fitted power-law spectra and decrease in the surface brightness is observed with increasing distance from the pulsar. In the second part of this paper, we introduce a model for the nonthermal emission, based on assuming the ideal magnetohydrodynamic limit. This model is used to constrain the parameters of the termination shock and the bulk velocity of the leptons in the PWN. Our model is able to reproduce the spatial variation of the X-ray spectra. The parameter ranges that we found agree well with the parameter estimates found by other authors with different approaches. In the last part of this paper, we calculate the inverse Compton emission from our model and compare it to the emission detected with the H.E.S.S. telescope system. Our model is able to reproduce the flux level observed with H.E.S.S., but not the spectral shape of the observed TeV {\gamma}-ray emission.Comment: Accepted for publication in A&A, 9 pages, 15 figure

    Impulse control disorders in dopamine agonist-treated hyperprolactinemia: Prevalence and risk factors

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    Context: There are growing reports of dopamine agonist (DA)-induced impulse control disorders (ICDs) in hyperprolactinemic patients. However, the magnitude of this risk and predictive factors remain uncertain. Objective: To determine ICD prevalence and risk factors in DA-treated hyperprolactinemic patients compared to community controls. Design, Setting and Participants: Multicenter cross-sectional analysis of 113 patients and 99 healthy controls. Main Outcome Measures: Participants completed a neuropsychological questionnaire consisting of the Depression Anxiety Stress Scale (DASS21), Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s disease (QUIP-S), Hypersexual Behavior Inventory (HBI), Hypersexual Behavior Consequences Scale and Social Desirability Response Set Scale. Demographic and clinical data were collated to determine ICD risk factors. Patients testing positive for an ICD were offered a semi-structured psychological interview. Results: Patients were more likely than controls to test positive by QUIP-S for any ICD (61.1 vs 42.4%, P=0.01), hypersexuality (22.1 vs 8.1%, P=0.009), compulsive buying (15.9 vs 6.1%, P=0.041) and punding (18.6 vs 6.1%, P=0.012), and by HBI for hypersexuality (8.0 vs 0.0%, P=0.004). Independent risk factors were male sex (OR 13.85), eugonadism (OR 7.85), Hardy’s tumor score, and psychiatric comorbidity (OR 6.86) for hypersexuality; and age (OR 0.95) for compulsive buying. DASS21 subset scores were higher in patients vs controls, and in patients with vs without different ICDs. Only 19/51 (37.3%) interviewed patients were aware of the relationship between DAs and ICDs before the study. Conclusions: DA therapy poses a high, previously underestimated risk of ICDs, especially in the form of hypersexuality in eugonadal men

    Prevalence of comorbidities in women with and without breast cancer in Soweto South Africa: Results from the SABC study

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    Background. Comorbidities occurring concurrently in breast cancer patients can be burdensome, as they may negatively influence time and stage of presentation.Objectives. To describe the comorbid health conditions among South African (SA) black women with and without breast cancer and to determine factors associated with advanced-stage presentation of breast cancer.Methods. A population-based case-control study on breast cancer was conducted in black women in Soweto, SA, the SABC (South Africa Breast Cancer) study. Lifestyle information and blood samples were collected from 399 women with histologically confirmed new cases of invasive primary breast cancer, recruited prior to any therapy, and 399 age- and neighbourhood-matched controls without breast cancer. We compared self-reported metabolic diseases, depression, anthropometric measurements, blood pressure, HIV status and point-of-care lipid and glucose levels between patients with breast cancer and the control group.Results. In the whole population, the mean (standard deviation) age was 54.6 (12.9) years, the majority (81.2%) of the participants were overweight or obese, 85.3% had abdominal adiposity, 61.3% were hypertensive, 47.1% had impaired fasting plasma glucose, 8.4% had elevated total cholesterol, 74.8% had low high-density lipoprotein and 10.9% were assessed to be depressed. Ninety-one percent of the whole cohort had at least one metabolic disease. In the breast cancer group, 72.2% had one or more metabolic diseases only (HIV-negative and no evidence of depression), compared with 64.7% of the control group. From a multivariate logistic regression adjusted model, higher household socioeconomic status conferred a 19% reduction in the odds of having advanced-stage breast cancer at diagnosis, while hypertension, dyslipidaemia and HIV were not significantly associated with stage at breast cancer diagnosis in the adjusted model.Conclusions. A large proportion of women experience several comorbidities, highlighting the need to address the chronic non-communicable disease epidemic in SA and to co-ordinate multidisciplinary primary-, secondary- and tertiary-level care in the country’s complex healthcare system for better outcome.Â
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