On Stone sublattices of the lattice of totally local Fitting classes

Totally local Fitting classes with a Stone lattice of totally local Fitting subclasses are described

Leonid Shemetkov. His entire life devotion

It is given a short scientific biography of Professor L.A. Shemetkov

Investigating social class inequalities in educational attainment : The effects of schools and the validity of free school meal status as a proxy for scio-economic status

EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Development of Compositions and Production Technology for Gels with a Solid Dispersal of Nitrofural

Compositions of gels with solid dispersions of nitrofural at a concentration of 0.04% were screened. Studies of the organoleptic properties, identity, assay of active ingredient, pH, and release led to selection of four compositions. The shelf life was determined (two years) and the storage conditions for the gel compositions developed here were identified. The proposed production technology for gels with solid dispersals of nitrofural yielded stable compositions with an active ingredient concentration of 0.04%, providing higher levels of nitrofural release than the currently available 0.2% furacillin ointment due to greater solubility and a greater rate of dissolution of active ingredient. © 2020, Springer Science+Business Media, LLC, part of Springer Nature

Dissolution of Ketoprofen from Poly(Ethylene Glycol) Solid Dispersions

The effect of solid dispersions (SDs) on the solubility of the nonsteroidal anti-inflammatory drug ketoprofen was determined. Ketoprofen and its SDs with poly(ethylene glycol) PEG-400, -1000, -1500, -2000, and -3000 were studied. Dissolution of ketoprofen from the SDs increased by 1.2 – 1.8 times; the dissolution rate, by 1.7 – 2.4 times. The improved release of ketoprofen from the SDs was proposed to be due to several factors such as solubilization and amorphization of the compound and formation of intermolecular H-bonds. The results could be used to develop rapidly dissolving ketoprofen solid dosage forms. © 2019, Springer Science+Business Media, LLC, part of Springer Nature

Solubility of Diclofenac Acid Form from Solid Dispersions

The influence of solid dispersions (SD) on diclofenac solubility was determined by studying diclofenac (acid form) and its SD with polyethyleneglycol-1500 (PEG) and polyvinylpyrrolidone-10000 (PVP). SD formation increased the solubility and dissolution rate of the non-steroidal anti-inflammatory drug (NSAID). Diclofenac solubility from the SD with PVP increased by 2.5 times; from the SD with PEG (solvent evaporation method), by 8 times compared with diclofenac drug substance. A combination of physicochemical methods showed that the improved release of diclofenac from the SD occurred because of reduced crystallinity, formation of drug solid solutions in the polymer matrix, and formation of a colloidal drug solution. © 2015, Springer Science+Business Media New York

Preparation and Investigation of Tabletted Medicinal Formulations of a Solid Dispersion of Rutin

Asolid dispersion of rutin based on polyvinylpyrrolidone had greater solubility than rutin substance, which is valuable for creating effective formulations based on this material. We describe here the preparation of tableted medicinal formulations of a solid dispersion of rutin prepared by direct pressing and moist granulation. A comparative analysis of the resulting granulates and tablets in terms of the main physical-technical characteristics is presented. © 2015, Springer Science+Business Media New York

Preparation and Investigation of Tabletted Medicinal Formulations of a Solid Dispersion of Rutin

Asolid dispersion of rutin based on polyvinylpyrrolidone had greater solubility than rutin substance, which is valuable for creating effective formulations based on this material. We describe here the preparation of tableted medicinal formulations of a solid dispersion of rutin prepared by direct pressing and moist granulation. A comparative analysis of the resulting granulates and tablets in terms of the main physical-technical characteristics is presented. © 2015, Springer Science+Business Media New York

Solubility of Diclofenac Acid Form from Solid Dispersions

The influence of solid dispersions (SD) on diclofenac solubility was determined by studying diclofenac (acid form) and its SD with polyethyleneglycol-1500 (PEG) and polyvinylpyrrolidone-10000 (PVP). SD formation increased the solubility and dissolution rate of the non-steroidal anti-inflammatory drug (NSAID). Diclofenac solubility from the SD with PVP increased by 2.5 times; from the SD with PEG (solvent evaporation method), by 8 times compared with diclofenac drug substance. A combination of physicochemical methods showed that the improved release of diclofenac from the SD occurred because of reduced crystallinity, formation of drug solid solutions in the polymer matrix, and formation of a colloidal drug solution. © 2015, Springer Science+Business Media New York