An intrinsically disordered proteins community for ELIXIR.

Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are now recognised as major determinants in cellular regulation. This white paper presents a roadmap for future e-infrastructure developments in the field of IDP research within the ELIXIR framework. The goal of these developments is to drive the creation of high-quality tools and resources to support the identification, analysis and functional characterisation of IDPs. The roadmap is the result of a workshop titled "An intrinsically disordered protein user community proposal for ELIXIR" held at the University of Padua. The workshop, and further consultation with the members of the wider IDP community, identified the key priority areas for the roadmap including the development of standards for data annotation, storage and dissemination; integration of IDP data into the ELIXIR Core Data Resources; and the creation of benchmarking criteria for IDP-related software. Here, we discuss these areas of priority, how they can be implemented in cooperation with the ELIXIR platforms, and their connections to existing ELIXIR Communities and international consortia. The article provides a preliminary blueprint for an IDP Community in ELIXIR and is an appeal to identify and involve new stakeholders

The supernova-nucleosynthesis 40Ca (α,γ) 44Ti reaction

The 44Ti (t1/2 = 59 y) nuclide is considered an important signature of core-collapse supernova (SN) nucleosynthesis and has recently been observed as live radioactivity by γ-ray astronomy from the Cas A SN remnant. We investigated in the laboratory the major 44Ti production reaction 40Ca(α,γ)44Ti (E cm ∼ 0.6-1.2 MeV/u) by off-line counting of 44Ti nuclei using accelerator mass spectrometry. The observed yield is significantly higher than inferred from previous prompt γ-spectroscopy experiments. The present data are interpreted in terms of the BRUSLIB statistical model which incorporates a microscopic model of nuclear level densities and of the γ-ray strength function, and a global α-nucleus optical-model potential and confirm the strong suppression in yield expected for (α,γ) reactions on self-conjugate (N =Z) nuclei. The derived astrophysical rate of the 40Ca(α,γ)44Ti reaction is a factor 5-10 higher than calculated in current models. We will present results of stellar calculations in spherical hydrodynamics using this reaction rate, showing an increase of the calculated SN 44Ti yield by a factor ∼ 2 over current estimates. An increase by a factor of ∼ 2 in 44Ti is found also in the calculated fall back material. The yields calculated by multi-dimensional SN explosion calculations proposed to explain the observed 44Ti yield of Cas A, in which parts of deeper layers can be ejected while some of the outer layers fall back, are expected to be enhanced in 44Ti as well.SCOPUS: cp.pinfo:eu-repo/semantics/publishe

New AMS Method to Measure the Atom Ratio 146Sm/147Sm for a Half-life Determination of 146Sm

info:eu-repo/semantics/publishe

An intrinsically disordered proteins community for ELIXIR.

Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are now recognised as major determinants in cellular regulation. This white paper presents a roadmap for future e-infrastructure developments in the field of IDP research within the ELIXIR framework. The goal of these developments is to drive the creation of high-quality tools and resources to support the identification, analysis and functional characterisation of IDPs. The roadmap is the result of a workshop titled "An intrinsically disordered protein user community proposal for ELIXIR" held at the University of Padua. The workshop, and further consultation with the members of the wider IDP community, identified the key priority areas for the roadmap including the development of standards for data annotation, storage and dissemination; integration of IDP data into the ELIXIR Core Data Resources; and the creation of benchmarking criteria for IDP-related software. Here, we discuss these areas of priority, how they can be implemented in cooperation with the ELIXIR platforms, and their connections to existing ELIXIR Communities and international consortia. The article provides a preliminary blueprint for an IDP Community in ELIXIR and is an appeal to identify and involve new stakeholders

Nucleosynthesis Reactions With The High-intensity Saraf-lilit Neutron Source

International audienceWe present a status report of recent neutron capture experiments performed with the mA-proton beam (1.92 MeV, 3 kW) of the Soreq Applied Research Accelerator Facility (SARAF) and the Liquid-Lithium Target (LiLiT). Experiments and preliminary results for (n) reactions on 36,38Ar, studied for the first time with 30-keV neutrons, on natKr, natCe and on radioactive targets 147Pm and 171Tm are described

Deutsche Forschungsanstalt fuer Luft- und Raumfahrt, Internationales Buero. Jahresbericht 1996

Available from FIZ Karlsruhe / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany)DEGerman