An isotropic magnetic-field transducer based on the giant magnetic impedance effect

A comparative analysis of the giant magnetoimpedance effect and the results of a mathe- matic simulation are presented. This simulation was used for optimizing the topology of a wide-angle magnetic transducer equipped with a sensitive element that consists of two crossed Fe3Co 67Cr3Si15B12 amorphous ribbons that form different angles between them. © 2013 Pleiades Publishing, Ltd

Laser cooling of a magnetically guided ultra cold atom beam

We report on the transverse laser cooling of a magnetically guided beam of ultra cold chromium atoms. Radial compression by a tapering of the guide is employed to adiabatically heat the beam. Inside the tapered section heat is extracted from the atom beam by a two-dimensional optical molasses perpendicular to it, resulting in a significant increase of atomic phase space density. A magnetic offset field is applied to prevent optical pumping to untrapped states. Our results demonstrate that by a suitable choice of the magnetic offset field, the cooling beam intensity and detuning, atom losses and longitudinal heating can be avoided. Final temperatures below 65 microkelvin have been achieved, corresponding to an increase of phase space density in the guided beam by more than a factor of 30.Comment: 9 pages, 4 figure

Thin film magnetoimpedance sensor for detection of stray fields in 3D-configuration

This work was performed under financial support of The Ministry of Education and Science of the Russian Federation, project № 2582

Transferability of the PRS estimates for height and BMI obtained from the European ethnic groups to the Western Russian populations

Genetic data plays an increasingly important role in modern medicine. Decrease in the cost of sequencing with subsequent increase in imputation accuracy, and the accumulation of large amounts of high-quality genetic data enable the creation of polygenic risk scores (PRSs) to perform genotype–phenotype associations. The accuracy of phenotype prediction primarily depends on the overall trait heritability, Genome-wide association studies cohort size, and the similarity of genetic background between the base and the target cohort. Here we utilized 8,664 high coverage genomic samples collected across Russia by “Evogen”, a Russian biomedical company, to evaluate the predictive power of PRSs based on summary statistics established on cohorts of European ancestry for basic phenotypic traits, namely height and BMI. We have demonstrated that the PRSs calculated for selected traits in three distinct Russian populations, recapitulate the predictive power from the original studies. This is evidence that GWAS summary statistics calculated on cohorts of European ancestry are transferable onto at least some ethnic groups in Russia

Magnetic and magnetoimpedance properties of rapidly quenched ribbons of modified alloys based on FINEMET

Amorphous and nanocrystalline materials are attractive systems for basic research and technological applications. In a view of the energy economy and global warming concepts there is a request to search for soft magnetic materials for sensor applications, which do not request additional heat treatments and can be produced in most simple technological scheme. In this work the structure, static magnetic properties and magnetoimpedance (MI) were studied for FINEMET-type materials both with classic composition and for compositions with 10 % of iron substitution by Co, Ni, or Mn in initial state, i.e. without any additional heat treatmnet. The best MI responses were obtained for Mn-doped rapidly quenched ribbons. © Published under licence by IOP Publishing Ltd.Ministry of Education and Science of the Russian Federation, Minobrnauka: 3.6121.2017/8.9The results were obtained under financial support of the state task of the Ministry of Education and Science of Russia 3.6121.2017/8.9. We thank D. Schishkin for special support

Five problems in legal maintenance of IT projects

Objective: to assess the compliance of traditional approaches to IT projects legal maintenance with the modern methods of organizing the process of digital products development, to identify the existing problems in this area and suggest possible ways to resolve them. Methods: the research used the logical method and the method of analyzing judicial practice, the inductive method, the method of comparison, and the method of scientific abstraction. Results: digitalization facilitated the development of the services market for IT projects and their maintenance. Legal maintenance of such projects often faces a significant discrepancy between the positions of the customer and the contractor, especially when part of the project is accomplished. Based on the analysis of judicial practice of IT projects using the Agile methodology, the most significant and problematic legal aspects of implementation were identified, and conflict situations between customers and performers of IT projects were analyzed.Scientific novelty: five key problems of IT projects legal maintenance that use flexible management methods are identified. A universal model for implementing legal functions in Agile projects is proposed.Practical significance: the proposed scheme of legal maintenance of IT projects can be used to regulate the legal relationships of their participants and may help to reduce the conflict level and speed up the process of digital products development using the Agile methodology

Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations

The taxonomy of the family Filoviridae (marburgviruses and ebolaviruses) has changed several times since the discovery of its members, resulting in a plethora of species and virus names and abbreviations. The current taxonomy has only been partially accepted by most laboratory virologists. Confusion likely arose for several reasons: species names that consist of several words or which (should) contain diacritical marks, the current orthographic identity of species and virus names, and the similar pronunciation of several virus abbreviations in the absence of guidance for the correct use of vernacular names. To rectify this problem, we suggest (1) to retain the current species names Reston ebolavirus, Sudan ebolavirus, and Zaire ebolavirus, but to replace the name Cote d'Ivoire ebolavirus [sic] with Taï Forest ebolavirus and Lake Victoria marburgvirus with Marburg marburgvirus; (2) to revert the virus names of the type marburgviruses and ebolaviruses to those used for decades in the field (Marburg virus instead of Lake Victoria marburgvirus and Ebola virus instead of Zaire ebolavirus); (3) to introduce names for the remaining viruses reminiscent of jargon used by laboratory virologists but nevertheless different from species names (Reston virus, Sudan virus, Taï Forest virus), and (4) to introduce distinct abbreviations for the individual viruses (RESTV for Reston virus, SUDV for Sudan virus, and TAFV for Taï Forest virus), while retaining that for Marburg virus (MARV) and reintroducing that used over decades for Ebola virus (EBOV). Paying tribute to developments in the field, we propose (a) to create a new ebolavirus species (Bundibugyo ebolavirus) for one member virus (Bundibugyo virus, BDBV); (b) to assign a second virus to the species Marburg marburgvirus (Ravn virus, RAVV) for better reflection of now available high-resolution phylogeny; and (c) to create a new tentative genus (Cuevavirus) with one tentative species (Lloviu cuevavirus) for the recently discovered Lloviu virus (LLOV). Furthermore, we explain the etymological derivation of individual names, their pronunciation, and their correct use, and we elaborate on demarcation criteria for each taxon and virus.S

MAGNETODYNAMIC STUDY OF THE FERROLIQUID CURRENT IN BLOOD VESSELS OF COMPLEX GEOMETRY: FOCUS ON MAGNETIC DETECTION SYSTEMS

The aim of this work is to develop a computer model of the hemodynamic flow in real blood vessels with magnetic nanoparticles, to assess the possibility of using a magnetic sensor based on the effect of giant magnetoimpedance for visualization of the structure of arterial system.Работа выполнена при поддержке гранта РНФ 18-19-00090

Effects of constant magnetic field to the proliferation rate of human fibroblasts grown onto different substrates: Tissue culture polystyrene, polyacrylamide hydrogel and ferrogels γ-fe2o3 magnetic nanoparticles

The static magnetic field was shown to affect the proliferation, adhesion and differentiation of various types of cells, making it a helpful tool for regenerative medicine, though the mechanism of its impact on cells is not completely understood. In this work, we have designed and tested a magnetic system consisting of an equidistant set of the similar commercial permanent magnets (6 × 4 assay) in order to get insight on the potential of its experimental usage in the biological studies with cells culturing in a magnetic field. Human dermal fibroblasts, which are widely applied in regenerative medicine, were used for the comparative study of their proliferation rate on tissue culture polystyrene (TCPS) and on the polyacrylamide ferrogels with 0.00, 0.63 and 1.19 wt % concentrations of γ-Fe2O3 magnetic nanoparticles obtained by the well-established technique of laser target evaporation. We used either the same batch as in previously performed but different biological experiments or the same fabrication conditions for fabrication of the nanoparticles. This adds special value to the understanding of the mechanisms of nanoparticles contributions to the processes occurring in the living systems in their presence. The magnetic field increased human dermal fibroblast cell proliferation rate on TCPS, but, at the same time, it suppressed the growth of fibroblasts on blank gel and on polyacrylamide ferrogels. However, the proliferation rate of cells on ferrogels positively correlated with the concentration of nanoparticles. Such a dependence was observed both for cell proliferation without the application of the magnetic field and under the exposure to the constant magnetic field. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.The Russian Scientific Foundation (grant 18-19-00090) supported the experimental parts of this study, including the design, performance and analysis of experiments