Upaya Meningkatkan Kemandirian Belajar Siswa melalui Lesson Study di Kelas V SD Negeri Lampageu Aceh Besar

Dalam konteks interaksi belajar mengajar di kelas siswa kurag mandiri, penelitian ini berupaya mengungkapkan upaya peningkatan kemandirian belajar siswa melalui lesson study. Secara khusus penelitian ini bertujuan (1) untuk mengetahui peningkatan kemandirian belajar siswa melalui lesson study di kelass V SD Negeri Lampageu Aceh Besar dan (2) untuk mengetahui aktifitas siswa dan guru dalam proses pembelajaran melalui lesson study di kelas V SD Negeri Lampageu Aceh Besar. Subjek penelitian ini adalah siswa kelas V SD Negeri Lampageu Aceh Besar, sebanyak 15 siswa yang terdiri dari 6 siswa laki-laki dan 9 siswa perempuan. Pelaksanaan lesson study dimulai dari tanggal 05 september 2016 sampai 19 september 2016. Jenis penelitian ini deskriptif dengan menggunakan pendekatan kualitatif, pengumpulan data dilakukan melalui teknik observasi aktifitas siswa dan wawancara guru. Teknik pengumpulan data menggunakan statistic sederhana untuk melihat atau mencari nilai rata-rata jawaban responden. Berdasarkan hasil analisis data observasi belajar siswa memperoleh nilai rata-rata pada pertemuan pertama sebanyak 2,896, kedua 3,413, dan ketiga sebanyak 3,6928. Analisis nilai rata-rata sudah ada peningkatan kemandirian belajar siswa pada setiap pertemuan. Hasil wawancara menunjukkan bahwa siswa senang dan sangat bersemangat dengan kegiatan pembelajaran yang dilakukan. Kesimpulan penelitian ini menunjukkan bahwa siswa kelas V SD Negeri Lampageu Aceh Besar sangat antusias dan bersemangat, sehingga interaksi proses belajar mengajar dapat berlangsung seperti yang diharapkan

In Vivo IS6110 profile changes in a Mycobacterium tuberculosis strain as determined by tracking over 14 years

Transposition and homologous recombination of IS6110 appear in Mycobacterium tuberculosis along in vivo sequential infec- tions. These events were checked in different clones of a successful strain, M. tuberculosis Zaragoza, with the focus on a variant in which integration of a copy of IS6110 in the origin of replication (oriC) region occurred

Assessment of the effect of a new technique for laparoscopic partial closure of the inguinal canal on sperm production and testicular perfusion in stallions

In order to simplify other laparoscopic techniques, a new standing laparoscopic technique for partial closure of inguinal canal (PCIC) has been developed. This technique uses a new anchoring device and can be performed without advanced laparoscopic skills. The aim of this study was to develop a prior evaluation of the effects of this new technique on the stallion reproductive capacity, assessing the sperm production and testicular perfusion. Standing laparoscopic PCIC was performed unilaterally in 8 experimental stallions without evidence of inguinal hernia, using the contralateral canal and testicle as control

Route Towards a Label-free Optical Waveguide Sensing Platform Based on Lossy Mode Resonances

According to recent market studies of the North American company Allied Market Research, the field of photonic sensors is an emerging strategic field for the following years and it is expected to garner $18 billion by 2021. The integration of micro and nanofabrication technologies in the field of sensors has allowed the development of new technological concepts such as lab-on-a-chip, which have achieved extraordinary advances in terms of detection and applicability, for example in the field of biosensors. This continuous development has allowed that equipment consisting of many complex devices that occupied a whole room a few years ago, at present it is possible to handle them in the palm of the hand; that formerly long duration processes are carried out in a matter of milliseconds and that a technology previously dedicated solely to military or scientific uses is available to the vast majority of consumers. The adequate combination of micro and nanostructured coatings with optical fiber sensors has permitted us to develop novel sensing technologies, such as the first experimental demonstration of lossy mode resonances (LMRs) for sensing applications, with more than one hundred citations and related publications in high rank journals and top conferences. In fact, fiber optic LMR-based devices have been proven as devices with one of the highest sensitivity for refractometric applications. Refractive index sensitivity is an indirect and simple indicator of how sensitive the device is to chemical and biological species, topic where this proposal is focused. Consequently, the utilization of these devices for chemical and biosensing applications is a clear opportunity that could open novel and interesting research lines and applications as well as simplify current analytical methodologies. As a result, on the basis of our previous experience with LMR based sensors to attain very high sensitivities, the objective of this paper is presenting the route for the development of label-free optical waveguide sensing platform based on LMRs that enable to explore the limits of this technology for bio-chemosensing applications

Uso de anestesia intravenosa parcial en anestesia equina

La especie equina presenta una alta mortalidad perianestésica, siendo el paro cardíaco y las fracturas a la hora de la recuperación anestésica las causas más frecuentes. Ésto hace que sea necesario buscar alternativas que intenten reducir los riesgos que se asocian a la anestesia general (AG). La adición de agentes intravenosos (IV) a una anestesia general inhalatoria se denomina PIVA (partial intravenous anesthesia, anestesia intravenosa parcial en español). Ésta reduce los requerimientos de gases anestésicos, disminuyendo la depresión cardiorrespiratoria que éstos producen y su acumulación en el organismo, mejorando así la calidad de la recuperación anestésica. Es por ello que se ha realizado una revisión bibliográfica, con el objetivo de profundizar en el uso de esta técnica, además de una encuesta a veterinarios que practican habitualmente procedimientos anestésicos en caballos, con el fin de alcanzar una perspectiva más realista de este tema. Los agentes IV que con mayor frecuencia se utilizan junto con agentes inhalatorios son la lidocaína, la ketamina, los α2-agonistas y los opioides, pudiéndose administrar solos o en combinación. La elección de unos u otros, dependerá de los efectos que interese potenciar en la situación quirúrgica concreta en la que nos encontremos. Los resultados de la encuesta indican que la técnica PIVA está ampliamente extendida entre los anestesistas veterinarios de caballos, los cuales prefieren utilizar un solo agente IV, siendo los α2-agonistas los más utilizados.<br /

Global study of is6110 in a successful mycobacterium tuberculosis strain: Clues for deciphering its behavior and for its rapid detection

The Mycobacterium tuberculosis insertion sequence IS6110, besides being a very useful tool in molecular epidemiology, seems to have an impact on the biology of bacilli. In the present work, we mapped the 12 points of insertion of IS6110 in the genome of a successful strain named M. tuberculosis Zaragoza (which has been referred to as the MTZ strain). This strain, belonging to principal genetic group 3, caused a large unsuspected tuberculosis outbreak involving 85 patients in Zaragoza, Spain, in 2001 to 2004. The mapping of the points of insertion of IS6110 in the genome of the Zaragoza strain offers clues for a better understanding of the adaptability and virulence of M. tuberculosis. Surprisingly, the presence of one copy of IS6110 was found in Rv2286c, as was recently described for a successful Beijing sublineage. As a result of this analysis, a rapid method for detecting this particular M. tuberculosis strain has been designed

Comparison of autologous bone marrow and adipose tissue derived mesenchymal stem cells, and platelet rich plasma, for treating surgically induced lesions of the equine superficial digital flexor tendon

Several therapies have been investigated for equine tendinopathies, but satisfactory long term results have not been achieved consistently and a better understanding of the healing mechanism elicited by regenerative therapies is needed. The aim of this study was to assess the separate effects of autologous bone marrow (BM) and adipose tissue (AT) derived mesenchymal stem cells (MSCs), and platelet rich plasma (PRP), for treating lesions induced in the superficial digital flexor tendon (SDFT) of horses. Lesions were created surgically in both SDFTs of the forelimbs of 12 horses and were treated with BM-MSCs (six tendons), AT-MSCs (six tendons) or PRP (six tendons). The remaining six tendons received lactated Ringer''s solution as control. Serial ultrasound assessment was performed prior to treatment and at 2, 6, 10, 20 and 45 weeks post-treatment. At 45 weeks, histopathology and gene expression analyses were performed. At week 6, the ultrasound echogenicity score in tendons treated with BM-MSCs suggested earlier improvement, whilst all treatment groups reached the same level at week 10, which was superior to the control group. Collagen orientation scores on histological examination suggested a better outcome in treated tendons. Gene expression was indicative of better tissue regeneration after all treatments, especially for BM-MSCs, as suggested by upregulation of collagen type I, decorin, tenascin and matrix metalloproteinase III mRNA. Considering all findings, a clear beneficial effect was elicited by all treatments compared with the control group. Although differences between treatments were relatively small, BM-MSCs resulted in a better outcome than PRP and AT-MSCs

Lorentz and CPT symmetries in commutative and noncommutative spacetime

We investigate the fermionic sector of a given theory, in which massive and charged Dirac fermions interact with an Abelian gauge field, including a non standard contribution that violates both Lorentz and CPT symmetries. We offer an explicit calculation in which the radiative corrections due to the fermions seem to generate a Chern-Simons-like effective action. Our results are obtained under the general guidance of dimensional regularization, and they show that there is no room for Lorentz and CPT violation in both commutative and noncommutative spacetime.Comment: RevTex4, 7 pages, to be published in J. Phys.

Are anti-ganglioside antibodies detectable in serum from patients with critical illness myopathy and polyneuropathy?

Introduction: Critical illness myopathy (CIM) and polyneuropathy (CIP) are the most common cause of acquired weakness in intensive care units (ICU). However, its exact pathogenesis remains unclear. Abnormal excitability of muscle due to a sodium channelopathy is one of the mechanisms proposed. The aim of this study is to test for the presence of anti-ganglioside antibodies in serum from patients with CIM or both combined CIM/CIP, since there is evidence that they can cause reversible dysfunction of voltage-gated sodium channels.Methods: In a prospective way, we studied 35 patients admitted in ICU by weekly EMG. When positive spontaneous activity (PSA) was detected, a muscle biopsy was performed. Twenty patients met criteria of CIM; five of them also developed overlapping CIP. We did not detect any kind of abnormality in 10 patients during the follow up period. Sera were analyzed for the presence of anti-ganglioside antibodies (Ganglioside-profile 2 Euroline, Euroimmun). Results: Overall, positive reactivity against anti-GT1b was found in one patient with CIM, representing 2.8% (1/35) of the total sample.Conclusion: Reduced percentage of patients affected of CIM or CIM/CIP exhibits positive reactive against anti-ganglioside antibodies. Thus, it could be suggested they do not play a primary role in their pathogenesis. Key words: Critical illness myopathy, critical illness polineuropathy, difficult weaning, channelopathy, muscle fiber inexcitability, anti-ganglioside antibodies  DOI: http://dx.doi.org/10.17268/rmt.2020.v15i01.0

Non-alcoholic fatty liver in hereditary fructose intolerance

Background: Non-alcoholic fatty liver disease (NAFLD) is characterized by fat accumulation affecting &gt;5% of the liver volume that is not explained by alcohol abuse. It is known that fructose gives rise to NAFLD and it has been recently described that the ingestion of fructose in low amounts in aldolase B deficient mice is associated with the development of fatty liver. Therefore, it is reasonable that patients with HFI (Hereditary Fructose Intolerance) present fatty liver at diagnosis, but its prevalence in patients treated and with adequate follow-up is not well documented in the literature. The aim of this study is to analyze the association between HFI and NAFLD in treated patients. Methods: A cross-sectional observational study was conducted. The population comprised 16 genetically diagnosed HFI patients aged from 3 years to 48 and in dietary treatment of fructose, sorbitol and sacarose exclusion at least for two years. Blood samples were obtained for analytical studies and anthropometric measurements of each patient were performed. Results: Patients presented a Body Mass Index (BMI) of 17.9 ± 2.9 kg/m 2 . The HOMA index and Quick index were in normal range for our population. The S-adenosyl-methionine (SAM)/S-adenosyl-L-homocysteine (SAH) ratio was increased in the patients in whom this analysis was performed. By imaging techniques it was observed that 9 of the 16 patients presented fatty liver (7 by hepatic MRI). Of these 9 patients, only 3 presented hepatomegaly. 7 of 9 patients affected by the c.448G &gt; C mutation had fatty infiltration, of which three of them presented in addition hepatomegaly. Conclusions: There is a high prevalence of fatty liver in HFI patients and it is not related to obesity and insulin resistance. The diagnosis of fatty liver in HFI patients and, above all, the identification of new therapeutic approaches, can positively impact the quality of life of these patients