471 research outputs found
Properties of Exotic Matter for Heavy Ion Searches
We examine the properties of both forms of strange matter, small lumps of
strange quark matter (strangelets) and of strange hadronic matter (Metastable
Exotic Multihypernuclear Objects: MEMOs) and their relevance for present and
future heavy ion searches. The strong and weak decays are discussed separately
to distinguish between long-lived and short-lived candidates where the former
ones are detectable in present heavy ion experiments while the latter ones in
future heavy ion experiments, respectively. We find some long-lived strangelet
candidates which are highly negatively charged with a mass to charge ratio like
a anti deuteron (M/Z=-2) but masses of A=10 to 16. We predict also many
short-lived candidates, both in quark and in hadronic form, which can be highly
charged. Purely hyperonic nuclei are bound and have a negative charge while
carrying a positive baryon number. We demonstrate also that multiply charmed
exotics (charmlets) might be bound and can be produced at future heavy ion
colliders.Comment: 10 pages, 4 figures, uses IOP style and epsf.sty, to be published in
Journal of Physics, Proceedings of the International Symposium on Strangeness
in Quark Matter 1997, April 14-18, Thera (Santorini), Hellas. Corrected
typos, added comment about bag constant
Inhomogeneous Nucleation of Quark-Gluon Plasma in High Energy Nuclear Collisions
We estimate the probability that a hard nucleon-nucleon collision is able to
nucleate a seed of quark--gluon plasma in the surrounding hot and dense
hadronic matter formed during a central collision of two large nuclei at AGS
energies. The probability of producing at least one such seed is on the order
of 1-100\%. We investigate the influence of quark--gluon plasma formation on
the observed multiplicity distribution and find that it may lead to noticable
structure in the form of a bump or shoulder.Comment: 16 pages, latex and 12 ps figures available on reques
Designing creative spaces: An experimental examination of the effect of a nature poster on divergent thinking
This paper reports the results of an independent samples experiment designed to examine the effects of the presence of a large poster depicting a natural woodland scene on individual performance on two Divergent Thinking tasks. In comparison to the no-poster control condition, the presentation of a large poster depicting a nature scene was found to lead to greater levels of creativity as rated by judges who were blind to the experimental design. The effects of the large poster on Divergent Thinking were found to hold when controlling for Openness-to-Experience and Mood. Exploratory analyses of participant ratings of room characteristics indicated that the mechanism underlying the postersâ effect related to elevated stimulation
Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists
Using the available structural information of the chemokine receptor CXCR4, we present hit finding and hit exploration studies that make use of virtual fragment screening, design, synthesis and structure-activity relationship (SAR) studies. Fragment 2 was identified as virtual screening hit and used as a starting point for the exploration of 31âŻN-substituted piperidin-4-yl-methanamine derivatives to investigate and improve the interactions with the CXCR4 binding site. Additionally, subtle structural ligand changes lead to distinct interactions with CXCR4 resulting in a full to partial displacement of CXCL12 binding and competitive and/or non-competitive antagonism. Three-dimensional quantitative structure-activity relationship (3D-QSAR) and binding model studies were used to identify important hydrophobic interactions that determine binding affinity and indicate key ligand-receptor interactions
Hexokinase isoenzymes of RIN-m5F insulinoma cells. Expression of glucokinase gene in insulin-producing cells
Louis I. Kahn and Richard Kelly: collaborative design in creation of the luminous environment
As one of the most prominent architects of the twentieth century, Louis I. Kahn aspired to use natural light to shape his architecture. The lighting designer Richard Kelly, one of his close collaborators, had significant influence on modern architectural lighting design in the twentieth century. Kahn and Kelly designed the luminous environments in three art-gallery and museum buildings, The Yale University Art Gallery, the Kimbell Art Museum and the Yale Center for British Art. Collaboration between the architect and the lighting designer resulted in well-resolved lighting solutions. This research investigated the collaboration between Louis I. Kahn and Richard Kelly from both theoretical and pragmatic perspectives. In terms of the theoretical perspective, a detailed overview of their collaborative work is provided through literature review. In terms of the pragmatic perspective, the background of their cooperation and the technical details are presented. In addition, daylighting performance analysis of these three buildings through digital modelling was undertaken. This study found that the lighting design solutions produced together by Louis I. Kahn and Richard Kelly, especially the way of using daylight, have had significant impact on architectural space and the luminous environment. More importantly, this kind of collaborative working method could provide a useful reference and guidance for contemporary architecture and lighting design
Shared decision making in designing new healthcare environmentsâtime to begin improving quality
Empathy, engagement, entrainment: the interaction dynamics of aesthetic experience
A recent version of the view that aesthetic experience is based in empathy as inner
imitation explains aesthetic experience as the automatic simulation of actions,
emotions, and bodily sensations depicted in an artwork by motor neurons in the brain. Criticizing the simulation theory for committing to an erroneous concept of empathy and failing to distinguish regular from aesthetic experiences of art, I advance an alternative, dynamic approach and claim that aesthetic experience is enacted and skillful, based in the recognition of othersâ experiences as distinct from oneâs own. In combining insights from mainly psychology, phenomenology, and cognitive science, the dynamic approach aims to explain the emergence of aesthetic experience in terms of the reciprocal interaction between viewer and artwork. I argue that aesthetic experience emerges by participatory sense-making and revolves around movement as a means for creating meaning. While entrainment merely plays a preparatory part in this, aesthetic engagement constitutes the phenomenological side of coupling to an artwork and provides the context for exploration, and eventually for moving, seeing, and feeling with art. I submit that aesthetic experience emerges from bodily and emotional engagement with works of art via the complementary processes of the perceptionâaction and motionâemotion loops. The former involves the embodied
visual exploration of an artwork in physical space, and progressively structures and organizes visual experience by way of perceptual feedback from body movements made in response to the artwork. The latter concerns the movement qualities and shapes of implicit and explicit bodily responses to an artwork that cue emotion and thereby modulate over-all affect and attitude. The two processes cause the viewer to bodily and emotionally move with and be moved by individual works of art, and consequently to recognize another psychological orientation than her own, which explains how art can cause feelings of insight or awe and disclose aspects of life that are unfamiliar or novel to the viewer
Development of atypical parental behavior during an inpatient family preservation intervention program
Since failed reunification is a detrimental outcome for children, particularly infants and toddlers, the aim of this study was to gain insight into support to families in multiple-problem situations to help them achieve sustainable good-enough parenting. Therefore, we examined outcomes of an assessment-based inpatient family preservation program. We prepared a thorough target-population description (n = 70) using file analysis. Next, we examined atypical parental behavior during the intervention using the Atypical Maternal Behavior Instrument for Assessment and Classification with a repeated measures design (n = 30). The family files revealed a great number of issues at the family, parent, and child levels, such as practical matters, problems in parent functioning and between parents, and difficulties in the broader environment. We found a significant decline in three dimensions of atypical parental behavior over time. This program has great potential in supporting vulnerable families in their pursuit of family preservation
- âŠ