MyClothes : aplicación Android para la gestión inteligente de la ropa de tu armario

Este proyecto consiste en el desarrollo de una aplicación para dispositivos móviles, con sistema Android, para el control y gestión del vestuario particular de cada usuario, en el que, se recopilan las imágenes de la ropa y el calzado, pudiendo ser clasificadas por varios métodos. La aplicación permite la visualización simultánea de estas prendas, lo cual facilita la creación de conjuntos, los cuales se pueden almacenar en un calendario, de la propia aplicación, asignándolos a una fecha determinada, lo cual evitaría en gran manera la repetición de conjuntos en días específicos. También se facilita la sugerencia de un conjunto determinado para una fecha en concreto, en base a anteriores elecciones del usuario y la climatología actual. Con esto se pretende tener registrada toda la ropa y calzado del usuario, y verlo de una forma rápida y sencilla, en cualquier lugar donde se encuentre, a través de su dispositivo móvil. Por lo que sería muy útil también a la hora de salir de compras, para ver lo que se tiene y lo que se puede necesitar. Por lo que se piensa que esta aplicación puede ser muy interesante, debido al auge de la moda y de los centros comerciales en la actualidad, así como de la venta de dispositivos móviles, de los que casi nadie hoy en día carece.Grado en Ingeniería Informática de Servicios y Aplicacione

The family of DOF transcription factors in Brachypodium distachyon: phylogenetic comparison with rice and barley DOFs and expression profiling

ABSTRACT: Transcription factors (TFs) are proteins that have played a central role both in evolution and in domestication, and are major regulators of development in living organisms. Plant genome sequences reveal that approximately 7% of all genes encode putative TFs. The DOF (DNA binding with One Finger) TF family has been associated with vital processes exclusive to higher plants and to their close ancestors (algae, mosses and ferns). These are seed maturation and germination, light-mediated regulation, phytohormone and plant responses to biotic and abiotic stresses, etc. In Hordeum vulgare and Oryza sativa, 26 and 30 different Dof genes, respectively, have been annotated. Brachypodium distachyon has been the first Pooideae grass to be sequenced and, due to its genomic, morphological and physiological characteristics, has emerged as the model system for temperate cereals, such as wheat and barley. RESULTS: Through searches in the B. distachyon genome, 27 Dof genes have been identified and a phylogenetic comparison with the Oryza sativa and the Hordeum vulgare DOFs has been performed. To explore the evolutionary relationship among these DOF proteins, a combined phylogenetic tree has been constructed with the Brachypodium DOFs and those from rice and barley. This phylogenetic analysis has classified the DOF proteins into four Major Cluster of Orthologous Groups (MCOGs). Using RT-qPCR analysis the expression profiles of the annotated BdDof genes across four organs (leaves, roots, spikes and seeds) has been investigated. These results have led to a classification of the BdDof genes into two groups, according to their expression levels. The genes highly or preferentially expressed in seeds have been subjected to a more detailed expression analysis (maturation, dry stage and germination). CONCLUSIONS: Comparison of the expression profiles of the Brachypodium Dof genes with the published functions of closely related DOF sequences from the cereal species considered here, deduced from the phylogenetic analysis, indicates that although the expression profile has been conserved in many of the putative orthologs, in some cases duplication followed by subsequent divergence may have occurred (neo-functionalization)

QSAR and molecular docking modelling of anti-leishmanial activities of organic selenium and tellurium compounds

Leishmaniasis affects mainly rural areas and the poorest people in the world. A computational study of the antileishmanial activity of organic selenium and tellurium compounds was performed. The 3D structures of the compounds were optimized at the wb97xd/lanl2dz level and used in the quantitative structure-activity relationship (QSAR) analysis. The antileishmanial activity was measured by L. donovani β carbonic anhydrase inhibition (Ki) and the half-maximal inhibitory concentration (IC50) against L. infantum amastigotes. The dataset was divided into training (75%) and test sets (25%) by using a k-means clustering algorithm. For pKi prediction, model M3 with seven 3D topographic descriptors was characterized by the following statistical parameters: r 2 = 0.879, Q 2 LOO = 0.822, and Q 2 ext = 0.840. For pIC50 prediction, model M12 with six attributes was characterized by the following statistical parameters: r 2 = 0.907, Q 2 LOO = 0.824, and Q 2 ext = 0.795. Both models met all the requirements of Tropsha´s test, which implies predictions of pIC50 and pKi activities with high accuracy. Concomitantly, favourable interactions of the sulphonamide group with the Zn atom in the protein were revealed by the docking analysis

The BdGAMYB protein from Brachypodium distachyon interacts with BdDOF24 and regulates transcription of the BdCathB gene upon seed germination

This document is the Accepted manuscript of the following article: González-Calle, V., Iglesias-Fernández, R., Carbonero, P. et al. Planta (2014) 240: 539. The final publication is available at Springer via: https://doi.org/10.1007/s00425-014-2105-3.Main conclusion: BdDOF24 interacting with BdGAMYB regulates the BdCathB gene upon germination. During barley seed germination, hydrolytic enzymes (α-amylases, proteases, etc.) synthesized in the aleurone layer in response to gibberellins (GA), catalyse the mobilization of storage reserves accumulated in the endosperm during seed maturation. In Brachypodium distachyon, the BdCathB gene that encodes a Cathepsin B-like thiol-protease, orthologous to the wheat Al21 and barley HvCathB, is highly induced in germinating seeds and its expression is regulated by transcription factors (TFs) encoded by genes BdGamyb and BdDof24, orthologous to the barley HvGamyb and BPBF-HvDof24, respectively. Transcripts of both TF genes increase during germination and treatments with abscisic acid (ABA) or paclobutrazol (PAC, an inhibitor of GA biosynthesis) decrease mRNA expression of BdGamyb but do not affect that of BdDof24. Besides, proteins BdDOF24 and BdGAMYB interact in yeast-2 hybrid systems and in plant nuclei, and in transient expression assays in aleurone layers BdDOF24 is a transcriptional repressor and BdGAMYB is an activator of the BdCathB promoter, as occurs with the putative orthologous in barley BPBF-HvDOF24 and HvGAMYB. However, when both TFs are co-bombarded, BdDOF24 enhances the activation driven by BdGAMYB while BPBF-HvDOF24 strongly decreases the HvGAMYB-mediated activation of the BdCathB promoter. The different results obtained when BdDOF24 and BPBF-HvDOF24 interact with BdGAMYB and HvGAMYB are discussed.Peer reviewedFinal Accepted Versio

Inclusión de las personas con habilidades especiales y/o limitaciones físicas en la empresa Supermercados Peruanos S.A. – 2017

El presente trabajo de investigación tiene como finalidad dar a conocer al público en general que la empresa supermercados peruanos está optando por incluir en su staff de personal que labora para la empres a personas con habilidades especiales y/o limitaciones físicas, pues esto no es motivo para que las personas mencionadas no puedan desenvolverse. La empresa supermercados peruanos está dando el ejemplo con esta iniciativa quelas personas con habilidades especiales y/o limitaciones físicas, pueden desenvolver labores en la empresa, y así apoyar a estar personas que también necesitan trabajar y superar sus necesidades económicas para el desarrollo del país. Es por esto que la empresa supermercados peruanos quiere liderar con el ejemplo al apoyar a estas personas con habilidades especiales, y crear conciencia de que todos podemos ser útiles para nuestra sociedad y contribuir con el desarrollo de nuestro país.The purpose of this research work is to inform the general public that the Peruvian supermarkets company is choosing to include people with special abilities and / or physical limitations in its staff who work for the company, as this is not a reason so that the people mentioned can not cope. The Peruvian supermarkets company is setting the example with this initiative that people with special abilities and / or physical limitations can carry out tasks in the company, and thus support people who also need to work and overcome their economic needs for the development of the country. This is why the Peruvian supermarkets company wants to lead by example in supporting these people with special skills, and to create awareness that we can all be useful for our society and contribute to the development of our country.Trabajo de investigació

Mannans and endo-β-mannanases (MAN) in Brachypodium distachyon : Expression profiling and possible role of the BdMAN genes during coleorhiza-limited seed germination

© The Author 2015. Published by Oxford University Press on behalf of the Society for Experimental Biology. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.Immunolocalization of mannans in the seeds of Brachypodium distachyon reveals the presence of these polysaccharides in the root embryo and in the coleorhiza in the early stages of germination (12h), decreasing thereafter to the point of being hardly detected at 27h. Concurrently, the activity of endo-β-mannanases (MANs; EC 3.2.1.78) that catalyse the hydrolysis of β-1,4 bonds in mannan polymers, increases as germination progresses. The MAN gene family is represented by six members in the Brachypodium genome, and their expression has been explored in different organs and especially in germinating seeds. Transcripts of BdMAN2, BdMAN4 and BdMAN6 accumulate in embryos, with a maximum at 24-30h, and are detected in the coleorhiza and in the root by in situ hybridization analyses, before root protrusion (germination sensu stricto). BdMAN4 is not only present in the embryo root and coleorhiza, but is abundant in the de-embryonated (endosperm) imbibed seeds, while BdMAN2 and BdMAN6 are faintly expressed in endosperm during post-germination (36-42h). BdMAN4 and BdMAN6 transcripts are detected in the aleurone layer. These data indicate that BdMAN2, BdMAN4 and BdMAN6 are important for germination sensu stricto and that BdMAN4 and BdMAN6 may also influence reserve mobilization. Whether the coleorhiza in monocots and the micropylar endosperm in eudicots have similar functions, is discussed.Peer reviewedFinal Published versio

The family of DOF transcription factors in Brachypodium distachyon: BdDOF24 in germinating seeds

The DOF (DNA binding with One Finger) transcription factor (TF) family is characterized by a binding domain of 52 amino acid residues that is structured as a Cys2/Cys2 Zn2+ finger that recognizes the common core 5?-T/AAAAG-3? in the promoter regions of their target genes. DOF TFs have been associated with biological processes exclusive to higher plants and their close ancestors (algae, mosses and ferns)

Vertical conduction properties of few-layer epitaxial graphene / n-type 4H-SiC heterojunctions at cryogenic temperatures

Vertical diodes of epitaxial graphene on n 4H-SiC were investigated. The graphene Raman spectraexhibited a higher intensity in the G-line than the 2D-line, indicative of a few-layer graphene film.Rectifying properties improved at low temperatures as the reverse leakage decreased over six ordersof magnitude without freeze-out in either material. Carrier concentration of 10 16 cm 3in the SiCremained stable down to 15 K, while accumulation charge decreased and depletion width increasedin forward bias. The low barrier height of 0.08 eV and absence of recombination-induced emissionindicated majority carrier field emission as the dominant conduction mechanism

Pileta Integral. Miradas desde el siglo XXI. Nuevas Tecnologías para una cueva excepcional

La primera presentación, la más exhaustiva y completa del arte prehistórico de La Pileta se debe a Henri Breuil (Breuil et al., 1915). Este autor propone dos grandes fases, una paleolítica, distribuidas en tres ciclos artísticos paleolíticos y una segunda postpaleolítica. A mediados del siglo XX diversos autores realizaron revisiones parciales de algunos paneles (p.ej. F. Jordá o E. Ripoll). Más tarde, y en la década de 1970, Lya y Marcel Dams trabajan durante varios años en La Pileta pero sus calcos son poco fidedignos. Por último, en noviembre de 1985 y en el marco de su tesis doctoral, J.L. Sanchidrián Torti realiza una revisión del arte de La Pileta. Este autor ha publicado diversos trabajos sobre La Pileta (p.ej. Sanchidrián, 1997). La Pileta ha sido objeto de diversas campaña de excavación en la sala de Vacas y de los Murciélagos en 1912 y 1942. No obstante, ninguno de estas excavaciones ha sido presentada en detalle y de los materiales obtenidos no se conservan más que algunos de selección (vid. Cortés y Simón 2007, Cortes et al., 2016). En otro orden de cosas, el primer plano topográfico de la Cueva de la Pileta fue realizado por el cartógrafo Willoughby Verner en 1912 (Breuil et al., 1915). En 1932 se realiza una nueva topografía, probablemente basada en otra muy similar que se encuentra en el Archivo Temboury. Posteriormente, se realiza una topografía por parte de grupos espeleológicos y, años más tarde, se publica el realizado por el Grupo de Espeleólogos Marbellíes. No obstante, los planos topográficos levantados hasta el momento tenían un fin meramente espeleológico y carecían de la resolución y precisión necesarias para un uso arqueológico. A comienzos del siglo XXI, pusimos en marcha una investigación integral de La Pileta de la cual hemos ido avanzando algunas novedades (Cortés y Simón 2007, Cortes et al., 2016, 2019) y que pretendía abordar desde una perspectiva holística la complejidad del yacimiento.Consejería de Cultura de la Junta de Andalucía (España) HAR2013-44269-PConsejería de Cultura de la Junta de Andalucía (España) HAR2016-77789-