3,354 research outputs found

    RG Flow from ϕ4\phi^4 Theory to the 2D Ising Model

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    We study 1+1 dimensional ϕ4\phi^4 theory using the recently proposed method of conformal truncation. Starting in the UV CFT of free field theory, we construct a complete basis of states with definite conformal Casimir, C\mathcal{C}. We use these states to express the Hamiltonian of the full interacting theory in lightcone quantization. After truncating to states with CCmax\mathcal{C} \leq \mathcal{C}_{\max}, we numerically diagonalize the Hamiltonian at strong coupling and study the resulting IR dynamics. We compute non-perturbative spectral densities of several local operators, which are equivalent to real-time, infinite-volume correlation functions. These spectral densities, which include the Zamolodchikov CC-function along the full RG flow, are calculable at any value of the coupling. Near criticality, our numerical results reproduce correlation functions in the 2D Ising model.Comment: 31+12 page

    Midlatitude, Rayleigh-Mie-Raman Lidar for Observations from 15 to 120 km

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    Rayleigh lidar opened a portion of the atmosphere, from 30 to 90 km, to ground-based observations. Rayleigh-scatter observations were made at the Atmospheric Lidar Observatory (ALO) at Utah State University (USU) from 1993–2004 between 45 and 90 km. The lidar consisted of a 0.44-m diameter mirror, a frequency-doubled Nd:YAG laser opera\u27ng at 532-nm at 30- Hz at either 18- or 24-W, giving power- aperture products (PAPs) of 2.7- or 3.6- Wm2, respec\u27vely, and one detector channel. An example of what was accomplished with this system is shown as part of Fig. 1. The temperature climatology was based on ~5000 hours of observa\u27ons carried out over ~900 nights. The temperatures, with 3-km al\u27tude resolu\u27on, were averaged over periods of 31 days by 11 years. The ALO Rayleigh lidar is currently being upgraded, as indicated, as indicated in Fig. 1, to extend observations upward into the lower thermosphere and downward to the lower stratosphere

    Mid-Latiude Rayleigh-Mie-Raman Lidar for Observations from 15 to 120 km

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    Rayleigh lidar opened a portion of the atmosphere, from 30 to 90 km, to ground-based observations. Rayleigh-scatter observations were made at the Atmospheric Lidar Observatory (ALO) at Utah State University (USU) from 1993–2004 between 45 and 90 km. The lidar consisted of a 0.44-m diameter mirror, a frequency-doubled Nd:YAG laser opera\u27ng at 532-nm at 30- Hz at either 18- or 24-W, giving power- aperture products (PAPs) of 2.7- or 3.6- Wm2, respec\u27vely, and one detector channel. An example of what was accomplished with this system is shown as part of Fig. 1. The temperature climatology was based on ~5000 hours of observa\u27ons carried out over ~900 nights. The temperatures, with 3-km al\u27tude resolu\u27on, were averaged over periods of 31 days by 11 years. The ALO Rayleigh lidar is currently being upgraded, as indicated, as indicated in Fig. 1, to extend observations upward into the lower thermosphere and downward to the lower stratosphere

    Rayleigh Lidar Temperature Studies in the Upper Mesosphere and Lower Thermosphere

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    Rayleigh lidar technology opened the middle atmosphere (from 30–90 km) to ground-based observations. The upgraded system at the Atmospheric Lidar Observatory (ALO) on the campus of Utah State University (41.74, 111.81) has shown that these ground-based observations can be extended to 109 km, with the goal of reaching 120 km. The resultant study of short and long-term temperature trends, using Rayleigh lidar, contributes immensely to the overall understanding of the properties and dominant physical processes in the middle atmosphere and Mesosphere-Lower Thermosphere (MLT) region. Temperature variations on short time scales, from minutes to days, give insight into the effects of waves (gravity waves, tides, planetary waves), while climatological studies of temperatures can help in the study of global change throughout the atmosphere

    Gallus GBrowse: a unified genomic database for the chicken

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    Gallus GBrowse (http://birdbase.net/cgi-bin/gbrowse/gallus/) provides online access to genomic and other information about the chicken, Gallus gallus. The information provided by this resource includes predicted genes and Gene Ontology (GO) terms, links to Gallus In Situ Hybridization Analysis (GEISHA), Unigene and Reactome, the genomic positions of chicken genetic markers, SNPs and microarray probes, and mappings from turkey, condor and zebra finch DNA and EST sequences to the chicken genome. We also provide a BLAT server (http://birdbase.net/cgi-bin/webBlat) for matching user-provided sequences to the chicken genome. These tools make the Gallus GBrowse server a valuable resource for researchers seeking genomic information regarding the chicken and other avian species

    Targeting Ribosome Assembly Factors Selectively Protects p53 Positive Cells from Chemotherapeutic Agents

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    Many chemotherapeutic agents act in a nondiscriminatory fashion, targeting both cancerous and noncancerous cells in Sphase and Mphase. One approach to reduce the toxic side effects in normal tissue is to exploit the differences in p53 functionality between cancerous and noncancerous cells. For example, activating p53 signaling by nongenotoxic means can transiently arrest noncancerous p53 positive cells in G1 phase and protect them from the cytotoxic effects of chemotherapeutic drugs. However, since most cancerous cells have faulty p53 signaling, they will proceed to cycle, and continue to be affected by the drug. In this study we asked if this G1‐phase arrest and cytoprotection can be achieved by targeting ribosome biogenesis. Through the expression of a dominant negative mutant ribosome assembly factor Bop1, we were able to transiently inhibit rRNA maturation. Using this genetic model, we have shown that inhibition of rRNA maturation protects 3T3 cells from chemotherapeutic agents camptothecin and methotrexate
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