3,230 research outputs found

    Latitudinal extension of low-latitude scintillations measured with a network of GPS receivers

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    International audienceA latitudinal-distributed network of GPS receivers has been operating within Colombia, Peru and Chile with sufficient latitudinal span to measure the absolute total electron content (TEC) at both crests of the equatorial anomaly. The network also provides the latitudinal extension of GPS scintillations and TEC depletions. The GPS-based information has been supplemented with density profiles collected with the Jicamarca digisonde and JULIA power maps to investigate the background conditions of the nighttime ionosphere that prevail during the formation and the persistence of plasma depletions. This paper presents case-study events in which the latitudinal extension of GPS scintillations, the maximum latitude of TEC depletion detections, and the altitude extension of radar plumes are correlated with the location and extension of the equatorial anomaly. Then it shows the combined statistics of GPS scintillations, TEC depletions, TEC latitudinal profiles, and bottomside density profiles collected between September 2001 and June 2002. It is demonstrated that multiple sights of TEC depletions from different stations can be used to estimate the drift of the background plasma, the tilt of the plasma plumes, and in some cases even the approximate time and location of the depletion onset. This study corroborates the fact that TEC depletions and radar plumes coincide with intense levels of GPS scintillations. Bottomside radar traces do not seem to be associated with GPS scintillations. It is demonstrated that scintillations/depletions can occur when the TEC latitude profiles are symmetric, asymmetric or highly asymmetric; this is during the absence of one crest. Comparison of the location of the northern crest of the equatorial anomaly and the maximum latitude of scintillations reveals that for 90% of the days, scintillations are confined within the boundaries of the 50% decay limit of the anomaly crests. The crests of the anomaly are the regions where the most intense GPS scintillations and the deepest TEC depletions are encountered. In accord with early results, we observe that GPS scintillations/TEC depletions mainly occur when the altitude of the magnetic equator F-region is above 500km. Nevertheless, in many instances GPS scintillations and TEC depletions are observed to exist when the F-layer is well below 500km or to persist when the F-layer undergoes its typical nighttime descent. Close inspection of the TEC profiles during scintillations/depletions events that occur when the equatorial F-layer peak is below 500km altitude reveals that on these occasions the ratio of the crest-to-equator TEC is above 2, and the crests are displaced 10° or more from the magnetic equator. When the equatorial F-layer is above 500km, neither of the two requirements is needed, as the flux tube seems to be inherently unstable. We discuss these findings in terms of the Rayleigh-Taylor instability (RTI) mechanism for flux-tube integrated quantities. We advance the idea that the seeming control that the reverse fountain effect exerts on inhibiting or suppressing GPS scintillations may be related to the redistribution of the density and plasma transport from the crests of the anomaly toward the equatorial region and then to much lower altitudes, and the simultaneous decrease of the F-region altitude. These two effects originate a decrease in the crest/trough ratio and a reduction of the crests separation, making the whole flux tube more stable to the RTI. The correspondence between crest separation, altitude of the equatorial F-region, the onset of depletions, and the altitude (latitude) extension of plumes (GPS scintillations) can be used to track the fate of the density structures

    A Silvopastoral System in the North Atlantic Zone of Costa Rica: Combining Indigenous Timber Species with Dairy Pasture Swards

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    The objective of this study was to design, establish and monitor a silvo pastoral experiment on a dairy farm in the northern Atlantic region of Costa Rica. Indigenous timber species, Vochysia guatemalensis and Hyeronima alchorneoides were used together with or without the tropical pasture legume, Arachis pintoi in a split plot design with a 4 x 2 x 2 factorial arrangement. First year establishment was good for the tree component (2.3 to 10 % mortality) but poor for A. pintoi (4 to 5 % of sward). Poor legume establishment was attributed to lax grazing management and excess competition from existing Brachiaria sp. A. Pintoi was reestablished in July 1996 after an adjustment of stocking rate. This experimental project is planned for a 10 year period which corresponds to the expected rotation length for harvesting the indigenous timber species

    On extending actions of groups

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    Problems of dense and closed extension of actions of compact transformation groups are solved. The method developed in the paper is applied to problems of extension of equivariant maps and of construction of equivariant compactifications

    Xenoestrogens released from lacquer coatings in food cans

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    We present data showing that some foods preserved in lacquer-coated cans and the liquid in them may acquire estrogenic activity. Hormonal activity was measured using the E-screen bioassay. The biological activity of vegetables packed in cans was a result of plastic monomers used in manufacturing the containers. The plastic monomer bisphenol-A, identified by mass spectrometry, was found as a contaminant not only in the liquid of the preserved vegetables but also in water autoclaved in the cans. The amount of bisphenol-A in the extracts accounted for all the hormonal activity measured. Although the presence of other xenoestrogens cannot be ruled out, it is apparent that all estrogenic activity in these cans was due to bisphenol-A leached from the lacquer coating. The use of plastic in food-packaging materials may require closer scrutiny to determine whether epoxy resins and polycarbonates contribute to human exposure to xenoestrogens.This work was supported by grant 94/1551 from the Fondo de Investigaciones Sanitarias (FIS), Spanish Ministry of Health

    The Phylogeny of Rays and Skates (Chondrichthyes: Elasmobranchii) Based on Morphological Characters Revisited.

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    Elasmobranchii are relatively well-studied. However, numerous phylogenetic uncertainties about their relationships remain. Here, we revisit the phylogenetic evidence based on a detailed morphological re-evaluation of all the major extant batomorph clades (skates and rays), including several holomorphic fossil taxa from the Palaeozoic, Mesozoic and Cenozoic, and an extensive outgroup sampling, which includes sharks, chimaeras and several other fossil chondrichthyans. The parsimony and maximum-likelihood analyses found more resolved but contrasting topologies, with the Bayesian inference tree neither supporting nor disfavouring any of them. Overall, the analyses result in similar clade compositions and topologies, with the Jurassic batomorphs forming the sister clade to all the other batomorphs, whilst all the Cretaceous batomorphs are nested within the remaining main clades. The disparate arrangements recovered under the different criteria suggest that a detailed study of Jurassic taxa is of utmost importance to present a more consistent topology in the deeper nodes, as issues continue to be present when analysing those clades previously recognized only by molecular analyses (e.g., Rhinopristiformes and Torpediniformes). The consistent placement of fossil taxa within specific groups by the different phylogenetic criteria is promising and indicates that the inclusion of more fossil taxa in the present matrix will likely not cause loss of resolution, therefore suggesting that a strong phylogenetic signal can be recovered from fossil taxa

    Dioxinlike properties of a trichloroethylene combustion-generated aerosol.

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    Conventional chemical analyses of incineration by-products identify compounds of known toxicity but often fail to indicate the presence of other chemicals that may pose health risks. In a previous report, extracts from soot aerosols formed during incomplete combustion of trichloroethylene (TCE) and pyrolysis of plastics exhibited a dioxinlike response when subjected to a keratinocyte assay. To verify this dioxinlike effect, the complete extract, its polar and nonpolar fractions, some containing primarily halogenated aromatic hydrocarbons, were evaluated for toxicity using an embryo assay, for antiestrogenicity using primary liver cell cultures, and for the ability to transform the aryl hydrocarbon receptor into its DNA binding form using liver cytosol in a gel retardation assay. Each of these assays detect dioxinlike effects. Medaka (Oryzias latipes) embryos and primary liver cell cultures of rainbow trout (Oncorhynchus mykiss) were exposed to concentrations of extract ranging from 0.05 to 45 micrograms/l. Cardiotoxicity with pericardial, yolk sac, and adjacent peritoneal edema occurred after exposure of embryos to concentrations of 7 micrograms/l or greater. These same exposure levels were associated with abnormal embryo development and, at the higher concentrations, death. Some of the fractions were toxic but none was as toxic as the whole extract. In liver cells, total cellular protein and cellular lactate dehydrogenase activity were not altered by in vitro exposure to whole extract (0.05-25 micrograms/l). However, induction of cytochrome P4501A1 protein and ethoxyresorufin O-deethylase activity occurred. In the presence of whole extract, estradiol-dependent vitellogenin synthesis was reduced. Of the fractions, only fraction 1 (nonpolar) showed a similar trend, although vitellogenin synthesis inhibition was not significant. The soot extract and fractions bound to the Ah receptor and showed a significantly positive result in the gel retardation/DNA binding test. Chemical analyses using GC-MS with detection limits for 2,3,7,8-tetrachlorodibenzo-p-dioxin and dibenzofuran in the picomole range did not show presence of these compounds. Our results indicate that other chemicals associated with TCE combustion and not originally targeted for analysis may also pose health risks through dioxinlike mechanisms

    The crater lake of Ilamatepec (Santa Ana) volcano, El Salvador: insights into lake gas composition and implications for monitoring

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    We here present the first chemical characterization of the volcanic gas plume issuing from the Santa Ana crater lake, a hyper-acidic crater lake (pH of − 0.2 to 2.5) in north-western El Salvador. Our results, obtained during regular surveys in 2017 and 2018 using a Multi-GAS instrument, demonstrate a hydrous gas composition (H2O/SO2 ratios from 32 to 205) and SO2 as the main sulfur species (H2S/SO2 = 0.03–0.1). We also find that gas composition evolved during our investigated period, with the CO2/SO2 ratio decreasing by one order of magnitude from March 2017 (37.2 ± 9.7) to November 2018 (< 3). This compositional evolution toward more magmatic (SO2-rich) compositions is interpreted in the context of the long-term evolution of the volcano following its 2005 and 2007 eruptions. We find that, in spite of reduced (background-level) seismicity, the magmatic gas supply into the lake was one order of magnitude higher in March 2017 (total volatile flux: 20,200–30,200 t/day) than in the following periods (total volatile flux: 900–10,167 t/day). We propose that the elevated magmatic/hydrothermal transport in March 2017, combined with a 15% reduction in precipitation, caused the volume of the lake to decrease, ultimately reducing its sulfur absorbing and scrubbing capacity, and hence causing the gas plume CO2/SO2 ratio to decrease. The recently observed increases in temperature, acidity, and salinity of the lake are consistent with this hypothesis. We conclude that the installation of a continuous, fully-automated Multi-GAS is highly desirable to monitor any future change in lake plume chemistry, and hence the level of degassing activity

    The molecular hallmarks of primary and secondary vitreoretinal lymphoma

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    Vitreoretinal lymphoma (VRL) is a rare subtype of diffuse large B-cell lymphoma (DLBCL) considered a variant of primary central nervous system lymphoma (PCNSL). Diagnosis of VRL requires examination of vitreous fluid, but cytologic differentiation from uveitis remains difficult. Due to its rarity and difficulty in obtaining diagnostic material, little is known about the genetic profile of VRL. The aim of our study was to investigate the mutational profile of a large series of primary and secondary VRL. Targeted next generation sequencing using a custom panel containing the most frequent mutations in PCNSL was performed on 34 vitrectomy samples of 31 patients with VRL and negative controls with uveitis. In a subset of cases, genome-wide copy number alterations (CNA) were assessed using the Oncoscan platform. Mutations in MYD88 (74%), PIM1 (71%), CD79B (55%), IGLL5 (52%), TBL1XR1 (48%), ETV6 (45%) and 9p21/CDKN2A deletions (85%) were the most common alterations, with similar frequencies in primary (15), synchronous (3) or secondary (13) VRL. This mutational spectrum is similar to MYD88mut/CD79Bmut (MCD or cluster 5) DLBCL with activation of Toll-like and B-cell receptor pathways and CDKN2A loss, confirming their close relationship. Oncoscan analysis demonstrated a high number of CNAs (mean 18.6/case). Negative controls lacked mutations or CNAs. Using cell free DNA of vitreous fluid supernatant, mutations present in cellular DNA were reliably detected in all examined cases. Mutational analysis is a highly sensitive and specific tool for the diagnosis of VRL and can also be applied successfully to cell free DNA derived from the vitreous.Copyright © 2021 American Society of Hematology
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